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2008

Journal Article

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

2008

Journal Article

Animal models of Alzheimer's disease and frontotemporal dementia

Gotz, Jurgen and Ittner, Lars M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 (7), 532-544. doi: 10.1038/nrn2420

Animal models of Alzheimer's disease and frontotemporal dementia

2008

Journal Article

Neuroproteomics as a promising tool in Parkinson's disease research

Pienaar, Ilse S., Daniels, William M. U. and Gotz, Jurgen (2008). Neuroproteomics as a promising tool in Parkinson's disease research. Journal of Neural Transmission, 115 (10), 1413-1430. doi: 10.1007/s00702-008-0070-3

Neuroproteomics as a promising tool in Parkinson's disease research

2008

Journal Article

Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma

Ittner, Lars M., Schwerdtfeger, Kerstin, Kunz, Thomas H., Muff, Roman, Husmann, Knut, Grimm, Christian, Hafezi, Farhad, Langh, Karl S., Kurrer, Michael O., Gotz, Jurgen, Born, Walter and Fischer, Jan A. (2008). Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical Science, 114 (1-2), 49-58. doi: 10.1042/CS20070163

Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma

2008

Journal Article

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Drose, Stefan, Brandt, Ulrich, Fandrich, Marcus, Muller, Walter E. and Gotz, Jürgen (2008). Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine, 86 (11), 1255-1267. doi: 10.1007/s00109-008-0391-6

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

2007

Journal Article

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

Habicht G., Haupt C., Friedrich R.P., Hortschansky P., Sachse C., Meinhardt J., Wieligmann K., Gellermann G.P., Brodhun M., Gotz J., Halbhuber K.-J., Rocken C., Horn U. and Fandrich M. (2007). Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils. Proceedings of the National Academy of Sciences of the United States of America, 104 (49), 19232-19237. doi: 10.1073/pnas.0703793104

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

2007

Book Chapter

Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture models

Götz, Jürgen, David, Della C. and Ittner, Lars M. (2007). Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture models. Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. (pp. 198-215) London: Springer London. doi: 10.1007/978-1-84628-440-3_12

Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture models

2007

Journal Article

Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry

Hoerndli, Frederic J., Pelech, Steven, Papassotiropoulos, Andreas and Gotz, Juergen (2007). Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. European Journal of Neuroscience, 26 (1), 60-72. doi: 10.1111/j.1460-9568.2007.05618.x

Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry

2007

Journal Article

Possibilities for the prevention and treatment of cognitive impairment and dementia

Burke, David, Hickie, Ian, Breakspear, Michael and Gotz, Juergen (2007). Possibilities for the prevention and treatment of cognitive impairment and dementia. British Journal of Psychiatry, 190 (5), 371-372. doi: 10.1192/bjp.bp.106.033407

Possibilities for the prevention and treatment of cognitive impairment and dementia

2007

Conference Publication

A decade of tau transgenic animal models and beyond

Gotz J., Deters N., Doldissen A., Bokhari L., Ke Y., Wiesner A., Schonrock N. and Ittner L.M. (2007). A decade of tau transgenic animal models and beyond. doi: 10.1111/j.1750-3639.2007.00051.x

A decade of tau transgenic animal models and beyond

2007

Conference Publication

Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles

Rhein, V, Baysang, G., Meier, F., Ozmen, L., Bluethmann, H., Savaskan, E., Mueller-Spahn, F., Czech, C., Goetz, J. and Eckert, A. (2007). Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles. 25th Symposium of the Arbeitsgemeinschaft-Neuropsychopharmakologie-und-Pharmakopsychiatrie, Munich, Germany, 3-6 October 2007. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-2007-991813

Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles

2007

Journal Article

Loosening of a total hip arthroplasty due to metastasis Metastatisch bedingte lockerung einer hüfttotalendoprothese

Götz, Jürgen, Beckmann, J., Perlick, L., Handel, M. and Grifka, J. (2007). Loosening of a total hip arthroplasty due to metastasis Metastatisch bedingte lockerung einer hüfttotalendoprothese. Zeitschrift fur Orthopadie und Unfallchirurgie, 145 (6), 760-762. doi: 10.1055/s-2007-989300

Loosening of a total hip arthroplasty due to metastasis Metastatisch bedingte lockerung einer hüfttotalendoprothese

2007

Journal Article

Pronuclear injection for the production of transgenic mice

Ittner, Lars M. and Gotz, Juergen (2007). Pronuclear injection for the production of transgenic mice. Nature Protocols, 2 (5), 1206-1215. doi: 10.1038/nprot.2007.145

Pronuclear injection for the production of transgenic mice

2006

Journal Article

β-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes

David, Della C., Ittner, Lars M., Gehrig, Peter, Nergenau, Denise, Shepherd, Claire, Halliday, Glenda and Gotz, Juergen (2006). β-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes. Proteomics, 6 (24), 6566-6577. doi: 10.1002/pmic.200600634

β-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes

2006

Journal Article

Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation

Schild, Andreas, Schmidt, Karsten, Lim, Yun-An, Ke, Yazi, Ittner, Lars M., Hemmings, Brian A. and Gotz, Juergen (2006). Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation. International Journal of Developmental Neuroscience, 24 (7), 437-443. doi: 10.1016/j.ijdevneu.2006.08.005

Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation

2006

Journal Article

Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?

Goetz, Juergen, Ittner, Lars M. and Schonrock, Nicole (2006). Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?. Medical Journal of Australia, 185 (7), 381-384. doi: 10.5694/j.1326-5377.2006.tb00615.x

Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?

2006

Journal Article

Improvement of patient's therapy with acute coronary syndrome in rural areas: Importance of a medical network Verbesserung der Behandlung von Patienten mit akutem Koronarsyndrom durch Aufbau einer Netzwerkstruktur im ländlichen Raum

Härtel, D., Christel, E., Brockmeier, J., Cuneo, A., Zellerhoff, C., Götz, J., Hundhausen, T., Dammann, T. and Tebbe, U. (2006). Improvement of patient's therapy with acute coronary syndrome in rural areas: Importance of a medical network Verbesserung der Behandlung von Patienten mit akutem Koronarsyndrom durch Aufbau einer Netzwerkstruktur im ländlichen Raum. Notfall und Rettungsmedizin, 10 (6), 423-431. doi: 10.1007/s10049-007-0938-z

Improvement of patient's therapy with acute coronary syndrome in rural areas: Importance of a medical network Verbesserung der Behandlung von Patienten mit akutem Koronarsyndrom durch Aufbau einer Netzwerkstruktur im ländlichen Raum

2006

Journal Article

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

Götz, Jürgen, Ittner, Lars M. and Kins, Stefan (2006). Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?. Journal of Neurochemistry, 98 (4), 993-1006. doi: 10.1111/j.1471-4159.2006.03955.x

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

2006

Journal Article

Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice

Pennanen, L., Wolfer, D. P., Nitsch, R. M. and Gotz, J. (2006). Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice. Genes, Brain and Behavior, 5 (5), 369-379. doi: 10.1111/j.1601-183X.2005.00165.x

Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice

2006

Journal Article

Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice

Schild, Andreas, Ittner, Lars M. and Gotz, Juergen (2006). Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochemical and Biophysical Research Communications, 343 (4), 1171-1178. doi: 10.1016/j.bbrc.2006.03.066

Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice