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2008 Journal Article Pathogenetic mechanisms in Down SyndromeEinfeld, S., Goetz, J. and Holsinger, R. M. D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52 (10), 813-813. doi: 10.1111/j.1365-2788.2008.01119_7.x |
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2008 Conference Publication Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer's disease miceRhein, Virginie, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Droese, Stefan, Brandt, Ulrich, Mueller-Spahn, Franz, Czech, Christian, Goetz, Jurgen and Eckert, Anne (2008). Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer's disease mice. 15th European Bioenergetic Conference, Dublin Ireland, Jul 19-24, 2008. ELSEVIER SCIENCE BV. doi: 10.1016/j.bbabio.2008.05.335 |
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2008 Journal Article Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical culturesLim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008). Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 (15), 2188-2194. doi: 10.1016/j.febslet.2008.05.006 |
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2008 Journal Article Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytesBaur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008). Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 (6), 3099-3108. doi: 10.1128/JVI.02479-07 |
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2008 Conference Publication Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein responseGotz, J., David, D., Hoerndli, F., Ke, Y. D., Schonrock, N., Wiesner, A., Fath, T., Bokhari, L., Lim, Y.-A., Deters, N. and Ittner, L. M. (2008). Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response. Basel, Switzerland: S Karger. doi: 10.1159/000113696 |
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2008 Conference Publication Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic miceEckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Rhein, Virginie, Muller-Spahn, Franz, Gotz, Jürgen and Muller, Walter E. (2008). Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Basel, Switzerland: S Karger AG. doi: 10.1159/000113689 |
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2008 Journal Article Neuroproteomics as a promising tool in Parkinson's disease researchPienaar, Ilse S., Daniels, William M. U. and Gotz, Jurgen (2008). Neuroproteomics as a promising tool in Parkinson's disease research. Journal of Neural Transmission, 115 (10), 1413-1430. doi: 10.1007/s00702-008-0070-3 |
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2008 Journal Article Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucomaIttner, Lars M., Schwerdtfeger, Kerstin, Kunz, Thomas H., Muff, Roman, Husmann, Knut, Grimm, Christian, Hafezi, Farhad, Langh, Karl S., Kurrer, Michael O., Gotz, Jurgen, Born, Walter and Fischer, Jan A. (2008). Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical Science, 114 (1-2), 49-58. doi: 10.1042/CS20070163 |
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2008 Journal Article Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic miceEckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Drose, Stefan, Brandt, Ulrich, Fandrich, Marcus, Muller, Walter E. and Gotz, Jürgen (2008). Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine, 86 (11), 1255-1267. doi: 10.1007/s00109-008-0391-6 |
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2008 Journal Article Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?Goetz, Juergen, Ittner, Lars M., Faendrich, Marcus and Schonrock, Nicole (2008). Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?. Journal of Alzheimers Disease, 14 (4), 423-429. doi: 10.3233/JAD-2008-14410 |
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2008 Journal Article Divergent phosphorylation pattern of tau in P301L tau transgenic miceDeters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x |
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2008 Journal Article Animal models of Alzheimer's disease and frontotemporal dementiaGotz, Jurgen and Ittner, Lars M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 (7), 532-544. doi: 10.1038/nrn2420 |
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2007 Journal Article Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrilsHabicht G., Haupt C., Friedrich R.P., Hortschansky P., Sachse C., Meinhardt J., Wieligmann K., Gellermann G.P., Brodhun M., Gotz J., Halbhuber K.-J., Rocken C., Horn U. and Fandrich M. (2007). Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils. Proceedings of the National Academy of Sciences of the United States of America, 104 (49), 19232-19237. doi: 10.1073/pnas.0703793104 |
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2007 Book Chapter Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture modelsGötz, Jürgen, David, Della C. and Ittner, Lars M. (2007). Impact of β-amyloid on the tau pathology in tau transgenic mouse and tissue culture models. Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. (pp. 198-215) London: Springer London. doi: 10.1007/978-1-84628-440-3_12 |
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2007 Journal Article Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entryHoerndli, Frederic J., Pelech, Steven, Papassotiropoulos, Andreas and Gotz, Juergen (2007). Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. European Journal of Neuroscience, 26 (1), 60-72. doi: 10.1111/j.1460-9568.2007.05618.x |
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2007 Journal Article Possibilities for the prevention and treatment of cognitive impairment and dementiaBurke, David, Hickie, Ian, Breakspear, Michael and Gotz, Juergen (2007). Possibilities for the prevention and treatment of cognitive impairment and dementia. British Journal of Psychiatry, 190 (5), 371-372. doi: 10.1192/bjp.bp.106.033407 |
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2007 Journal Article Pronuclear injection for the production of transgenic miceIttner, Lars M. and Gotz, Juergen (2007). Pronuclear injection for the production of transgenic mice. Nature Protocols, 2 (5), 1206-1215. doi: 10.1038/nprot.2007.145 |
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2007 Conference Publication A decade of tau transgenic animal models and beyondGotz J., Deters N., Doldissen A., Bokhari L., Ke Y., Wiesner A., Schonrock N. and Ittner L.M. (2007). A decade of tau transgenic animal models and beyond. doi: 10.1111/j.1750-3639.2007.00051.x |
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2007 Conference Publication Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tanglesRhein, V, Baysang, G., Meier, F., Ozmen, L., Bluethmann, H., Savaskan, E., Mueller-Spahn, F., Czech, C., Goetz, J. and Eckert, A. (2007). Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles. 25th Symposium of the Arbeitsgemeinschaft-Neuropsychopharmakologie-und-Pharmakopsychiatrie, Munich, Germany, 3-6 October 2007. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-2007-991813 |
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2007 Journal Article Loosening of a total hip arthroplasty due to metastasis Metastatisch bedingte lockerung einer hüfttotalendoprotheseGötz, Jürgen, Beckmann, J., Perlick, L., Handel, M. and Grifka, J. (2007). Loosening of a total hip arthroplasty due to metastasis Metastatisch bedingte lockerung einer hüfttotalendoprothese. Zeitschrift fur Orthopadie und Unfallchirurgie, 145 (6), 760-762. doi: 10.1055/s-2007-989300 |
