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2009 Journal Article Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease miceRhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M., Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Drose, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Gotz, Jurgen and Eckert, Anne (2009). Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, 106 (47), 20057-20062. doi: 10.1073/pnas.0905529106 |
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2009 Journal Article Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's diseaseKe, Yazi D., Delerue, Fabien, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2009). Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS ONE, 4 (11) e7917, e7917.1-e7917.7. doi: 10.1371/journal.pone.0007917 |
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2009 Journal Article Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'Götz, Jürgen, Ittner, Lars M. and Lim, Yun-An (2009). Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'. Cellular and Molecular Life Sciences, 66 (17), 2945-2945. doi: 10.1007/s00018-009-0073-8 |
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2009 Journal Article Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer diseaseIttner, Lars M., Ke, Yazi D. and Gotz, Jurgen (2009). Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. Journal of Biological Chemistry, 284 (31), 20909-20916. doi: 10.1074/jbc.M109.014472 |
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2009 Conference Publication Axonal transport in tau transgenic mouse modelsGoetz, J. and Ittner, L. M. (2009). Axonal transport in tau transgenic mouse models. 4th European-Society-for-Neurochemistry Conference on Advances in Molecular Mechanisms of Neurological Disorders, Leipzig Germany, Jul 11-14, 2009. WILEY-BLACKWELL PUBLISHING, INC. |
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2009 Journal Article Common features between diabetes mellitus and Alzheimer's diseaseGötz, J., Ittner, L. M. and Lim, Y. A. (2009). Common features between diabetes mellitus and Alzheimer's disease. Cellular and Molecular Life Sciences, 66 (8), 1321-1325. doi: 10.1007/s00018-009-9070-1 |
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2009 Journal Article Substrate-specific reduction of PP2A activity exaggerates tau pathologyDeters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2009). Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and Biophysical Research Communications, 379 (2), 400-405. doi: 10.1016/j.bbrc.2008.12.140 |
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2009 Journal Article Primary support cultures of hippocampal and substantia nigra neuronsFath, Thomas, Ke, Yazi D., Gunning, Peter, Gotz, Jürgen and Ittner, Lars M. (2009). Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols, 4 (1), 78-85. doi: 10.1038/nprot.2008.199 |
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2009 Journal Article Alzheimer's disease selective vulnerability and modeling in transgenic MiceGotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009). Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 (2), 243-251. doi: 10.3233/JAD-2009-1143 |
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2009 Journal Article Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brainsvan Eersel, Janet, Bi, Mian, Ke, Yazi D., Hodges, John R., Xuereb, John H., Gregory, Gillian C., Halliday, Glenda M., Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2009). Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of Neural Transmission, 116 (10), 1243-1251. doi: 10.1007/s00702-009-0293-y |
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2009 Conference Publication Neurofibrillary pathology in the brainstem of the tau mutant pR5 mouseSchroeder, H., Goetz, J., Pilz, K., Kuhlage, S., de Vos, R. A. I., Bauer, T., Selzer, A. and Koehler, C. (2009). Neurofibrillary pathology in the brainstem of the tau mutant pR5 mouse. 9th International Conference on Alzheimers and Parkinson's Diseases (AD/PD), Prague Czech Republic, Mar 11-15, 2009. Bologna, Italy: Medimond. |
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2008 Journal Article An update on the toxicity of A-beta in Alzheimer's diseaseGötz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008). An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 (6), 1033-1042. doi: 10.2147/NDT.S3016 |
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2008 Journal Article Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementiaIttner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter and Gotz, Jurgen (2008). Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America, 105 (41), 15997-16002. doi: 10.1073/pnas.0808084105 |
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2008 Journal Article Pathogenetic mechanisms in Down SyndromeEinfeld, S., Goetz, J. and Holsinger, R. M. D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52 (10), 813-813. doi: 10.1111/j.1365-2788.2008.01119_7.x |
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2008 Conference Publication Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer's disease miceRhein, Virginie, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Droese, Stefan, Brandt, Ulrich, Mueller-Spahn, Franz, Czech, Christian, Goetz, Jurgen and Eckert, Anne (2008). Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer's disease mice. 15th European Bioenergetic Conference, Dublin Ireland, Jul 19-24, 2008. ELSEVIER SCIENCE BV. doi: 10.1016/j.bbabio.2008.05.335 |
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2008 Journal Article Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical culturesLim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008). Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 (15), 2188-2194. doi: 10.1016/j.febslet.2008.05.006 |
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2008 Journal Article Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytesBaur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008). Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 (6), 3099-3108. doi: 10.1128/JVI.02479-07 |
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2008 Conference Publication Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein responseGotz, J., David, D., Hoerndli, F., Ke, Y. D., Schonrock, N., Wiesner, A., Fath, T., Bokhari, L., Lim, Y.-A., Deters, N. and Ittner, L. M. (2008). Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response. Basel, Switzerland: S Karger. doi: 10.1159/000113696 |
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2008 Conference Publication Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic miceEckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Rhein, Virginie, Muller-Spahn, Franz, Gotz, Jürgen and Muller, Walter E. (2008). Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Basel, Switzerland: S Karger AG. doi: 10.1159/000113689 |
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2008 Journal Article Divergent phosphorylation pattern of tau in P301L tau transgenic miceDeters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x |
