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2014 Journal Article Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteomeLiang, Vanessa, Ullrich, Milena, Lam, Hong, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Kassiou, Michael, Gotz, Jürgen and Nicholas, Hannah R. (2014). Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome. Cellular and Molecular Life Sciences, 71 (17), 3339-3361. doi: 10.1007/s00018-014-1558-7 |
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2014 Journal Article Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegansUllrich, Milena, Liang, Vanessa, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Lam, Hong, Berber, Slavica, Kassiou, Michael, Nicholas, Hannah R. and Goetz, Juergen (2014). Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 9 (9), 2237-2255. doi: 10.1038/nprot.2014.150 |
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2014 Journal Article Tau-targeting passive immunization modulates aspects of pathology in tau transgenic miceIttner, Arne, Bertz, Josefine, Suh, Lisa S., Stevens, Claire H., Gotz, Jurgen and Ittner, Lars M. (2014). Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. Journal of Neurochemistry, 132 (1), 1-11. doi: 10.1111/jnc.12821 |
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2014 Journal Article Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomousChew, Yee Lian, Fan, Xiaochen, Gotz, Jurgen and Nicholas, Hannah R. (2014). Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous. Scientific Reports, 4 (1) 5185, 5185. doi: 10.1038/srep05185 |
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2014 Journal Article Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of FynXia, Di and Gotz, Jurgen (2014). Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn. Frontiers in Molecular Neuroscience, 7 (MAY) 40, 1-11. doi: 10.3389/fnmol.2014.00040 |
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2014 Journal Article Visualizing the microtubule-associated protein tau in the nucleusLu, Jing, Li, Ting, He, RongQiao, Bartlett, Perry F. and Gotz, Jürgen (2014). Visualizing the microtubule-associated protein tau in the nucleus. Science China Life Sciences, 57 (4), 422-431. doi: 10.1007/s11427-014-4635-0 |
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2014 Journal Article The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cellsChen, JinYan, Sun, MengRu, Wang, XingHua, Lu, Jing, Wei, Yan, Tan, Yan, Liu, Ying, Gotz J., He, RongQiao and Hua, Qian (2014). The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells. Science China Life Sciences, 57 (4), 412-421. doi: 10.1007/s11427-014-4643-0 |
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2013 Journal Article Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleusLiu, Chang and Goetz, Juergen (2013). Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PloS One, 8 (12) e84849, e84849. doi: 10.1371/journal.pone.0084849 |
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2013 Journal Article March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's diseaseEckert, Anne, Nisbet, Rebecca, Grimm, Amandine and Götz, Jürgen (2013). March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease. Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease, 1842 (8), 1258-1266. doi: 10.1016/j.bbadis.2013.08.013 |
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2013 Journal Article Aging in the nervous system of Caenorhabditis elegansChew, Yee Lian, Fan, Xiaochen, Goetz, Juergen and Nicholas, Hannah R. (2013). Aging in the nervous system of Caenorhabditis elegans. Communicative and Integrative Biology, 6 (5) e25288, e25288.1-e25288.6. doi: 10.4161/cib.25288 |
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2013 Journal Article Lessons from two prevalent amyloidoses-what amylin and A beta have in commonGoetz, Juergen, Lim, Yun-An and Eckert, Anne (2013). Lessons from two prevalent amyloidoses-what amylin and A beta have in common. Frontiers in Aging Neuroscience, 5 (AUG) Article 38, 38.1-38.9. doi: 10.3389/fnagi.2013.00038 |
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2013 Journal Article Proximal interphalangeal joint replacement with an unconstrained pyrocarbon prosthesis (Ascension®): a long-term follow-upHeers, G., Springorum, H. R., Baier, C., Götz, J., Grifka, J. and Renkawitz, T. (2013). Proximal interphalangeal joint replacement with an unconstrained pyrocarbon prosthesis (Ascension®): a long-term follow-up. Journal of Hand Surgery: European Volume, 38 (6), 680-685. doi: 10.1177/1753193412469898 |
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2013 Journal Article What renders TAU toxicGoetz, Juergen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian and Nicholas, Hannah R. (2013). What renders TAU toxic. Frontiers in Neurology, 4 Article 72, 72.1-72.10. doi: 10.3389/fneur.2013.00072 |
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2013 Journal Article Why size matters - balancing mitochondrial dynamics in Alzheimer's diseaseDuBoff, Brian, Feany, Mel and Goetz, Juergen (2013). Why size matters - balancing mitochondrial dynamics in Alzheimer's disease. Trends in Neurosciences, 36 (6), 325-335. doi: 10.1016/j.tins.2013.03.002 |
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2013 Journal Article PTL-1 regulates neuronal integrity and lifespan in C-elegansChew, Yee Lian, Fan, Xiaochen, Goetz, Juergen and Nicholas, Hannah R. (2013). PTL-1 regulates neuronal integrity and lifespan in C-elegans. Journal of Cell Science, 126 (9), 2079-2091. doi: 10.1242/jcs.jcs124404 |
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2013 Journal Article Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylationNilsen, Linn Hege, Rae, Caroline, Ittner, Lars M., Goetz, Juergen and Sonnewald, Ursula (2013). Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation. Journal of Cerebral Blood Flow and Metabolism, 33 (5), 684-691. doi: 10.1038/jcbfm.2012.212 |
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2013 Journal Article Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic miceKoehler, Christoph, Dinekov, Maja and Goetz, Juergen (2013). Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice. Neurobiology of Aging, 34 (5), 1369-1379. doi: 10.1016/j.neurobiolaging.2012.11.010 |
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2013 Journal Article Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic miceMorcinek, Kerstin, Köhler, Christoph, Goetz, Juergen and Schröder, Hannsjorg (2013). Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice. Brain Research, 1497, 73-84. doi: 10.1016/j.brainres.2012.12.016 |
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2013 Journal Article Single nucleotide variants (SNVs) define senescence-accelerated SAMP8 mice, a model of a geriatric conditionDelerue, Fabien, Sjollema, Geoff, Whittle, Belinda, Krueger, Sarah, Andrews, Dan and Goetz, Juergen (2013). Single nucleotide variants (SNVs) define senescence-accelerated SAMP8 mice, a model of a geriatric condition. Journal of Alzheimers Disease, 36 (2), 349-363. doi: 10.3233/JAD-130089 |
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2013 Journal Article How it all started: Tau and protein phosphatase 2ALiu, Chang and Goetz, Juergen (2013). How it all started: Tau and protein phosphatase 2A. Journal of Alzheimer's Disease, 37 (3), 483-494. doi: 10.3233/jad-130503 |
