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2016

Journal Article

Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease

Liu, Chang, Song, Xiaomin, Nisbet, Rebecca and Goetz, Juergen (2016). Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease. Journal of Biological Chemistry, 291 (15), 8173-8188. doi: 10.1074/jbc.M115.641902

Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease

2016

Journal Article

A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

Baker, Sian and Götz, Jürgen (2016). A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. Acta Neuropathologica Communications, 4 (1) 32, 32.1-32.13. doi: 10.1186/s40478-016-0300-0

A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

2016

Journal Article

Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia

Van der Jeugd, Ann, Vermaercke, Ben, Halliday, Glenda M., Staufenbiel, Matthias and Gotz, Jürgen (2016). Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiology of Learning and Memory, 130, 34-43. doi: 10.1016/j.nlm.2016.01.007

Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia

2016

Journal Article

The frontotemporal dementia-motor neuron disease continuum

Burrell, James R., Halliday, Glenda M., Kril, Jillian J., Ittner, Lars M., Gotz, Jurgen, Kiernan, Matthew C. and Hodges, John R. (2016). The frontotemporal dementia-motor neuron disease continuum. The Lancet, 388 (10047), 919-931. doi: 10.1016/S0140-6736(16)00737-6

The frontotemporal dementia-motor neuron disease continuum

2016

Journal Article

Ultrasound treatment of neurological diseases — current and emerging applications

Leinenga, Gerhard, Langton, Christian, Nisbet, Rebecca and Gotz, Jurgen (2016). Ultrasound treatment of neurological diseases — current and emerging applications. Nature Reviews Neurology, 12 (3), 161-174. doi: 10.1038/nrneurol.2016.13

Ultrasound treatment of neurological diseases — current and emerging applications

2016

Conference Publication

The many facets of dementia - basic science and translational strategies

Gotz, Jurgen (2016). The many facets of dementia - basic science and translational strategies. Unknown, Unknown, Unknown. HOBOKEN: WILEY-BLACKWELL.

The many facets of dementia - basic science and translational strategies

2016

Conference Publication

Scanning Focused Ultrasound disruption of the blood-brain barrier as an Alzheimer’s disease therapy

Leinenga, Gerhard, Nisbet, Rebecca, Hatch, Robert, Van der Jeugd, Anneke, Evans, Harrison and Götz, Jürgen (2016). Scanning Focused Ultrasound disruption of the blood-brain barrier as an Alzheimer’s disease therapy. 5th International Symposium on Focused Ultrasound, Bethesda, MD United States, 28 August - 1 September 2016. London, United Kingdom: BioMed Central. doi: 10.1186/s40349-016-0076-5

Scanning Focused Ultrasound disruption of the blood-brain barrier as an Alzheimer’s disease therapy

2016

Journal Article

Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice

Baker, Sian, Polanco, Juan Carlos and Gotz, Juergen (2016). Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice. Journal of Alzheimer's Disease, 54 (3), 1207-1217. doi: 10.3233/JAD-160371

Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice

2016

Journal Article

Glutamate receptors in alzheimer's disease: mechanisms and therapies

Anggono, Victor, Tsai, Li-Huei and Goetz, Juergen (2016). Glutamate receptors in alzheimer's disease: mechanisms and therapies. Neural Plasticity, 2016 8256196, 8256196-2. doi: 10.1155/2016/8256196

Glutamate receptors in alzheimer's disease: mechanisms and therapies

2016

Conference Publication

SPECIFIC ALTERATIONS OF TAU PHOSPHORYLATION AND NEURONAL SIGNALING INDUCED BY THE AMYLOID-beta OLIGOMER A beta*56

Lesne, Sylvain, Amar, Fatou, Sherman, Mathew, Rush, Travis, Larson, Megan, Chang, Liu, Gotz, Jurgen, Schneider, Julie, Bennett, David, Ashe, Karen and Buisson, Alain (2016). SPECIFIC ALTERATIONS OF TAU PHOSPHORYLATION AND NEURONAL SIGNALING INDUCED BY THE AMYLOID-beta OLIGOMER A beta*56. 14th International Athens/Springfield Symposium on Advances In Alzheimer Therapy, Athens, Greece, Mar 09-12, 2016. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.neurobiolaging.2016.01.117

SPECIFIC ALTERATIONS OF TAU PHOSPHORYLATION AND NEURONAL SIGNALING INDUCED BY THE AMYLOID-beta OLIGOMER A beta*56

2016

Conference Publication

Scanning ultrasound as a treatment tool of proteinopathies including Alzheimer’s disease

Götz, Jürgen, Nisbet, Rebecca, Van der Jeugd, Ann, Evans, Harrison and Leinenga, Gerhard (2016). Scanning ultrasound as a treatment tool of proteinopathies including Alzheimer’s disease. 5th International Symposium on Focused Ultrasound, Bethesda, MD, USA, 28 August - 1 September 2016. London, United Kingdom: BioMed Central. doi: 10.1186/s40349-016-0076-5

Scanning ultrasound as a treatment tool of proteinopathies including Alzheimer’s disease

2015

Journal Article

No full admission for tau to the exclusive prion club yet

Polanco, Juan Carlos and Götz, Jürgen (2015). No full admission for tau to the exclusive prion club yet. EMBO Journal, 34 (24), 2990-2992. doi: 10.15252/embj.201593311

No full admission for tau to the exclusive prion club yet

2015

Journal Article

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

Grimm, Amandine, Biliouris, Emily E., Lang, Undine E., Gotz, Jurgen, Mensah-Nyagan, Ayikoe Guy and Eckert, Anne (2015). Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein. Cellular and Molecular Life Sciences, 73 (1), 201-215. doi: 10.1007/s00018-015-1988-x

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

2015

Journal Article

FTD and ALS—translating mouse studies into clinical trials

Ittner, Lars M., Halliday, Glenda M., Kril, Jillian J., Götz, Jürgen, Hodges, John R. and Kiernan, Matthew C. (2015). FTD and ALS—translating mouse studies into clinical trials. Nature Reviews Neurology, 11 (6), 360-366. doi: 10.1038/nrneurol.2015.65

FTD and ALS—translating mouse studies into clinical trials

2015

Journal Article

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

Xia, Di, Li, Chuanzhou and Gotz, Jurgen (2015). Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852 (5), 913-924. doi: 10.1016/j.bbadis.2014.12.017

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

2015

Journal Article

Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease

Cummins, Nadia and Götz, Jurgen (2015). Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease. Australian Biochemist, 46 (1), 4-7.

Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease

2015

Journal Article

Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model

Leinenga, Gerhard and Götz, Jürgen (2015). Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model. Science Translational Medicine, 7 (278) 278ra33, 278ra33.1-278ra33.12. doi: 10.1126/scitranslmed.aaa2512

Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model

2015

Journal Article

Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress

Chew, Yee Lian, Gotz, Jurgen and Nicholas, Hannah R. (2015). Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress. Aging Cell, 14 (1), 148-151. doi: 10.1111/acel.12285

Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress

2015

Journal Article

What we can learn from animal models about cerebral multi-morbidity

Baker, Sian and Gotz, Jurgen (2015). What we can learn from animal models about cerebral multi-morbidity. Alzheimer's Research and Therapy, 7 (11) 11, 11. doi: 10.1186/s13195-015-0097-2

What we can learn from animal models about cerebral multi-morbidity

2015

Conference Publication

Striatal deficits underlie conflicted patterns of action selection in ageing

Matamales, M., Skrbis, Z., Balleine, B., Goetz, J. and Bertran-Gonzalez, J. (2015). Striatal deficits underlie conflicted patterns of action selection in ageing. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188

Striatal deficits underlie conflicted patterns of action selection in ageing