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2017 Journal Article Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse modelNisbet, Rebecca M., Van der Jeugd, Ann, Leinenga, Gerhard, Evans, Harrison T., Janowicz, Phillip W. and Goetz, Juergen (2017). Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model. Brain, 140 (5), 1220-1230. doi: 10.1093/brain/awx052 |
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2017 Journal Article Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatologyAhmed, Rebekah M., Irish, Muireann, van Eersel, Janet, Ittner, Arne, Ke, Yazi D., Volkerling, Alexander, van der Hoven, Julia, Tanaka, Kimi, Karl, Tim, Kassiou, Michael, Kril, Jillian J., Piguet, Olivier, Goetz, Juergen, Kiernan, Matthew C., Halliday, Glenda M., Hodges, John R. and Ittner, Lars M. (2017). Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatology. Neuroscience and Biobehavioral Reviews, 74 (A), 126-138. doi: 10.1016/j.neubiorev.2017.01.004 |
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2017 Journal Article Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse modelBodea, Liviu-Gabriel, Evans, Harrison Tudor, Van der Jeugd, Ann, Ittner, Lars M., Delerue, Fabien, Kril, Jillian, Halliday, Glenda, Hodges, John, Kiernan, Mathew C. and Goetz, Juergen (2017). Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model. Aging Cell, 16 (2), 377-386. doi: 10.1111/acel.12565 |
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2016 Journal Article Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type miceHatch, Robert John, Leinenga, Gerhard and Götz, Jürgen (2016). Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice. PloS One, 11 (10) e0164278, e0164278. doi: 10.1371/journal.pone.0164278 |
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2016 Journal Article Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's diseaseJiao, S. -S., Shen, L. -L., Zhu, C., Bu, X. -L., Liu, Y. -H., Liu, C. -H., Yao, X. -Q., Zhang, L. -L., Zhou, H. -D., Walker, D. G., Tan, J., Goetz, J., Zhou, X. -F. and Wang, Y. -J. (2016). Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease. Translational Psychiatry, 6 (10) e907, e907-e907. doi: 10.1038/tp.2016.186 |
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2016 Journal Article Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregationChai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016 |
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2016 Journal Article Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'Brandt, Roland and Goetz, Juergen (2016). Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'. Brain Research Bulletin, 126 (3), 213-216. doi: 10.1016/j.brainresbull.2016.08.003 |
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2016 Journal Article Motor cortical function determines prognosis in sporadic ALSShibuya, Kazumoto, Park, Susanna B., Geevasinga, Nimeshan, Menon, Parvathi, Howells, James, Simon, Neil G., Huynh, William, Noto, Yu-ichi, Gotz, Jurgen, Kril, Jillian J., Ittner, Lars M., Hodges, John, Halliday, Glenda, Vucic, Steve and Kiernan, Matthew C. (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87 (5), 513-520. doi: 10.1212/WNL.0000000000002912 |
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2016 Journal Article Tau physiology and pathomechanisms in frontotemporal lobar degenerationBodea, Liviu-Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier and Götz, Juergen (2016). Tau physiology and pathomechanisms in frontotemporal lobar degeneration. Journal of Neurochemistry, 138 (S1), 71-94. doi: 10.1111/jnc.13600 |
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2016 Journal Article Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauXia, Di, Gutmann, Julia M. and Gotz, Jurgen (2016). Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau. Scientific Reports, 6 (1) 29074, 29074. doi: 10.1038/srep29074 |
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2016 Journal Article Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatumMatamales, Miriam, Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatum. PLoS One, 11 (6) e0157682, 1-13. doi: 10.1371/journal.pone.0157682 |
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2016 Journal Article Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent mannerPolanco, Juan Carlos, Scicluna, Benjamin James, Hill, Andrew Francis and Gotz, Jurgen (2016). Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent manner. Journal of Biological Chemistry, 291 (24), 12445-12466. doi: 10.1074/jbc.M115.709485 |
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2016 Journal Article Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selectionMatamales, Miriam, Skrbis, Zala, Hatch, Robert J., Balleine, Bernard W., Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selection. Neuron, 90 (2), 362-373. doi: 10.1016/j.neuron.2016.03.006 |
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2016 Journal Article Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in diseaseLiu, Chang, Song, Xiaomin, Nisbet, Rebecca and Goetz, Juergen (2016). Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease. Journal of Biological Chemistry, 291 (15), 8173-8188. doi: 10.1074/jbc.M115.641902 |
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2016 Journal Article A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regionsBaker, Sian and Götz, Jürgen (2016). A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. Acta Neuropathologica Communications, 4 (1) 32, 32.1-32.13. doi: 10.1186/s40478-016-0300-0 |
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2016 Journal Article Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementiaVan der Jeugd, Ann, Vermaercke, Ben, Halliday, Glenda M., Staufenbiel, Matthias and Gotz, Jürgen (2016). Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiology of Learning and Memory, 130, 34-43. doi: 10.1016/j.nlm.2016.01.007 |
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2016 Journal Article The frontotemporal dementia-motor neuron disease continuumBurrell, James R., Halliday, Glenda M., Kril, Jillian J., Ittner, Lars M., Gotz, Jurgen, Kiernan, Matthew C. and Hodges, John R. (2016). The frontotemporal dementia-motor neuron disease continuum. The Lancet, 388 (10047), 919-931. doi: 10.1016/S0140-6736(16)00737-6 |
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2016 Journal Article Ultrasound treatment of neurological diseases — current and emerging applicationsLeinenga, Gerhard, Langton, Christian, Nisbet, Rebecca and Gotz, Jurgen (2016). Ultrasound treatment of neurological diseases — current and emerging applications. Nature Reviews Neurology, 12 (3), 161-174. doi: 10.1038/nrneurol.2016.13 |
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2016 Conference Publication The many facets of dementia - basic science and translational strategiesGotz, Jurgen (2016). The many facets of dementia - basic science and translational strategies. Unknown, Unknown, Unknown. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Scanning Focused Ultrasound disruption of the blood-brain barrier as an Alzheimer’s disease therapyLeinenga, Gerhard, Nisbet, Rebecca, Hatch, Robert, Van der Jeugd, Anneke, Evans, Harrison and Götz, Jürgen (2016). Scanning Focused Ultrasound disruption of the blood-brain barrier as an Alzheimer’s disease therapy. 5th International Symposium on Focused Ultrasound, Bethesda, MD United States, 28 August - 1 September 2016. London, United Kingdom: BioMed Central. doi: 10.1186/s40349-016-0076-5 |
