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2017 Journal Article Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?Cummins, Nadia and Götz, Jürgen (2017). Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?. Cellular and Molecular Life Sciences, 75 (7), 1-12. doi: 10.1007/s00018-017-2692-9 |
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2017 Journal Article A corticostriatal deficit promotes temporal distortion of automatic action in ageingMatamales, Miriam, Skrbis, Zala, Bailey, Matthew R, Balsam, Peter D, Balleine, Bernard W, Götz, Jürgen and Bertran-Gonzalez, Jesus (2017). A corticostriatal deficit promotes temporal distortion of automatic action in ageing. eLife, 6 e29908. doi: 10.7554/eLife.29908 |
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2017 Journal Article Tau-based therapies in neurodegeneration: opportunities and challengesLi, Chuanzhou and Götz, Jürgen (2017). Tau-based therapies in neurodegeneration: opportunities and challenges. Nature Reviews Drug Discovery, 16 (12), 863-883. doi: 10.1038/nrd.2017.155 |
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2017 Journal Article Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation.Li, Chuanzhou and Götz, Jürgen (2017). Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation.. EMBO Journal, 36 (17), 3120-3138. doi: 10.15252/embj.201797724 |
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2017 Journal Article Ultrasound as a treatment modality for neurological diseasesLeinenga, Gerhard, Nisbet, Rebecca M. and Gotz, Jurgen (2017). Ultrasound as a treatment modality for neurological diseases. Medical Journal of Australia, 206 (11), 470-471. doi: 10.5694/mja16.01013 |
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2017 Journal Article The amyloid-β oligomer Aβ∗56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregationAmar, Fatou, Sherman, Mathew A., Rush, Travis, Larson, Megan, Boyle, Gabriel, Chang, Liu, Gotz, Jurgen, Buisson, Alain and Lesne, Sylvain E. (2017). The amyloid-β oligomer Aβ∗56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Science Signaling, 10 (478) aal2021, eaal2021. doi: 10.1126/scisignal.aal2021 |
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2017 Journal Article Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segmentHatch, Robert John, Wei, Yan, Xia, Di and Gotz, Jürgen (2017). Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment. Acta Neuropathologica, 133 (5), 717-730. doi: 10.1007/s00401-017-1674-1 |
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2017 Journal Article Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse modelNisbet, Rebecca M., Van der Jeugd, Ann, Leinenga, Gerhard, Evans, Harrison T., Janowicz, Phillip W. and Goetz, Juergen (2017). Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model. Brain, 140 (5), 1220-1230. doi: 10.1093/brain/awx052 |
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2017 Journal Article Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatologyAhmed, Rebekah M., Irish, Muireann, van Eersel, Janet, Ittner, Arne, Ke, Yazi D., Volkerling, Alexander, van der Hoven, Julia, Tanaka, Kimi, Karl, Tim, Kassiou, Michael, Kril, Jillian J., Piguet, Olivier, Goetz, Juergen, Kiernan, Matthew C., Halliday, Glenda M., Hodges, John R. and Ittner, Lars M. (2017). Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatology. Neuroscience and Biobehavioral Reviews, 74 (A), 126-138. doi: 10.1016/j.neubiorev.2017.01.004 |
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2017 Journal Article Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse modelBodea, Liviu-Gabriel, Evans, Harrison Tudor, Van der Jeugd, Ann, Ittner, Lars M., Delerue, Fabien, Kril, Jillian, Halliday, Glenda, Hodges, John, Kiernan, Mathew C. and Goetz, Juergen (2017). Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model. Aging Cell, 16 (2), 377-386. doi: 10.1111/acel.12565 |
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2016 Journal Article Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type miceHatch, Robert John, Leinenga, Gerhard and Götz, Jürgen (2016). Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice. PloS One, 11 (10) e0164278, e0164278. doi: 10.1371/journal.pone.0164278 |
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2016 Journal Article Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's diseaseJiao, S. -S., Shen, L. -L., Zhu, C., Bu, X. -L., Liu, Y. -H., Liu, C. -H., Yao, X. -Q., Zhang, L. -L., Zhou, H. -D., Walker, D. G., Tan, J., Goetz, J., Zhou, X. -F. and Wang, Y. -J. (2016). Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease. Translational Psychiatry, 6 (10) e907, e907-e907. doi: 10.1038/tp.2016.186 |
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2016 Journal Article Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregationChai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016 |
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2016 Journal Article Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'Brandt, Roland and Goetz, Juergen (2016). Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'. Brain Research Bulletin, 126 (3), 213-216. doi: 10.1016/j.brainresbull.2016.08.003 |
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2016 Journal Article Motor cortical function determines prognosis in sporadic ALSShibuya, Kazumoto, Park, Susanna B., Geevasinga, Nimeshan, Menon, Parvathi, Howells, James, Simon, Neil G., Huynh, William, Noto, Yu-ichi, Gotz, Jurgen, Kril, Jillian J., Ittner, Lars M., Hodges, John, Halliday, Glenda, Vucic, Steve and Kiernan, Matthew C. (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87 (5), 513-520. doi: 10.1212/WNL.0000000000002912 |
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2016 Journal Article Tau physiology and pathomechanisms in frontotemporal lobar degenerationBodea, Liviu-Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier and Götz, Juergen (2016). Tau physiology and pathomechanisms in frontotemporal lobar degeneration. Journal of Neurochemistry, 138 (S1), 71-94. doi: 10.1111/jnc.13600 |
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2016 Journal Article Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauXia, Di, Gutmann, Julia M. and Gotz, Jurgen (2016). Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau. Scientific Reports, 6 (1) 29074, 29074. doi: 10.1038/srep29074 |
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2016 Journal Article Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatumMatamales, Miriam, Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatum. PLoS One, 11 (6) e0157682, 1-13. doi: 10.1371/journal.pone.0157682 |
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2016 Journal Article Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent mannerPolanco, Juan Carlos, Scicluna, Benjamin James, Hill, Andrew Francis and Gotz, Jurgen (2016). Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent manner. Journal of Biological Chemistry, 291 (24), 12445-12466. doi: 10.1074/jbc.M115.709485 |
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2016 Journal Article Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selectionMatamales, Miriam, Skrbis, Zala, Hatch, Robert J., Balleine, Bernard W., Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selection. Neuron, 90 (2), 362-373. doi: 10.1016/j.neuron.2016.03.006 |
