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2013 Journal Article Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosisPinto, Rachel, Leotta, Lisa, Shanahan, Erin R., West, Nicholas P., Leyh, Thomas S., Britton, Warwick and Triccas, James A. (2013). Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis. Journal of Infectious Diseases, 207 (5), 778-785. doi: 10.1093/infdis/jis751 |
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2012 Journal Article Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration StrategyAnh Thu Tran, West, Nicholas P., Britton, Warwick J. and Payne, Richard J. (2012). Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy. Chemmedchem, 7 (6), 1031-1043. doi: 10.1002/cmdc.201100606 |
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2012 Journal Article The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in MiceKao, Fan F., Mahmuda, Sultana, Pinto, Rachel, Triccas, James A., West, Nicholas P. and Britton, Warwick J. (2012). The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in Mice. PLoS One, 7 (5) e34991, e34991. doi: 10.1371/journal.pone.0034991 |
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2012 Journal Article Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active siteManos-Turvey, Alexandra, Cergol, Katie M., Salam, Noeris K., Bulloch, Esther M. M., Chi, Gamma, Pang, Angel, Britton, Warwick J., West, Nicholas P., Baker, Edward N., Lott, J. Shaun and Payne, Richard J. (2012). Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site. Organic and Biomolecular Chemistry, 10 (46), 9223-9236. doi: 10.1039/c2ob26736e |
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2011 Journal Article Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosisWest, Nicholas P., Thomson, Scott A., Triccas, James A., Medveczky, C. Jill, Ramshaw, Ian A. and Britton, Warwick J. (2011). Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis. Vaccine, 29 (44), 7759-7765. doi: 10.1016/j.vaccine.2011.07.109 |
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2011 Journal Article Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug LeadsAnh Thu Tran, Cergol, Katie M., West, Nicholas P., Randall, Elizabeth J., Britton, Warwick J., Bokhari, Syed Ali Imran, Ibrahim, Musadiq, Lapthorn, Adrian J. and Payne, Richard J. (2011). Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug Leads. Chemmedchem, 6 (2), 262-265. doi: 10.1002/cmdc.201000399 |
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2011 Journal Article Immunity to mycobacterium tuberculosisTriccas, James A., Winter, Nathalie, Feng, Carl G. and West, Nicholas P. (2011). Immunity to mycobacterium tuberculosis. Clinical & Developmental Immunology, 2011 (406549) 406549, 1-2. doi: 10.1155/2011/406549 |
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2011 Journal Article Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leadsWest, Nicholas P., Cergol, Katie M., Xue, Millie, Randall, Elizabeth J., Britton, Warwick J. and Payne, Richard J. (2011). Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads. Chemical Communications, 47 (18), 5166-5168. doi: 10.1039/c0cc05635a |
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2010 Journal Article Tetrahydrolipstatin Inhibition, Functional Analyses, and Three-dimensional Structure of a Lipase Essential for Mycobacterial ViabilityCrellin, Paul K., Vivian, Julian P., Scoble, Judith, Chow, Frances M., West, Nicholas P., Brammananth, Rajini, Proellocks, Nicholas I., Shahine, Adam, Le Nours, Jerome, Wilce, Matthew C. J., Britton, Warwick J., Coppel, Ross L., Rossjohn, Jamie and Beddoe, Travis (2010). Tetrahydrolipstatin Inhibition, Functional Analyses, and Three-dimensional Structure of a Lipase Essential for Mycobacterial Viability. Journal of Biological Chemistry, 285 (39), 30050-30060. doi: 10.1074/jbc.M110.150094 |
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2010 Journal Article Modulation of Shigella virulence in response to available oxygen in vivoMarteyn, Benoit, West, Nicholas P., Browning, Douglas F., Cole, Jeffery A., Shaw, Jonathan G., Palm, Fredrik, Mounier, Joelle, Prevost, Marie-Christine, Sansonetti, Philippe and Tang, Christoph M. (2010). Modulation of Shigella virulence in response to available oxygen in vivo. Nature, 465 (7296), 355-358+2. doi: 10.1038/nature08970 |
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2010 Journal Article Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccineShanahan, Erin R., Pinto, Rachel, Triccas, James A., Britton, Warwick J. and West, Nicholas P. (2010). Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccine. Vaccine, 28 (5), 1341-1346. doi: 10.1016/j.vaccine.2009.11.010 |
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2009 Journal Article Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identificationWest, Nicholas P., Chow, Frances M. E., Randall, Elizabeth J., Wu, Jing, Chen, Jian, Ribeiro, Jose M. C. and Britton, Warwick J. (2009). Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. Faseb Journal, 23 (6), 1694-1704. doi: 10.1096/fj.08-114421 |
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2008 Journal Article Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosisWest, Nicholas P., Wozniak, Teresa M., Valenzuela, Jesus, Feng, Carl G., Sher, Alan, Ribeiro, Jose M. C. and Britton, Warwick J. (2008). Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis. Vaccine, 26 (31), 3853-3859. doi: 10.1016/j.vaccine.2008.05.007 |
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2005 Journal Article Available carbon source influences the resistance of Neisseria meningitidis against complementExley, RM, Shaw, J, Mowe, E, Sun, YH, West, NP, Williamson, M, Botto, M, Smith, H and Tang, CM (2005). Available carbon source influences the resistance of Neisseria meningitidis against complement. Journal of Experimental Medicine, 201 (10), 1637-1645. doi: 10.1084/jem.20041548 |
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2005 Journal Article Optimization of virulence functions through glucosylation of Shigella LPSWest, NP, Sansonetti, P, Mounier, J, Exley, RM, Parsot, C, Guadagnini, S, Prevost, MC, Prochnicka-Chalufour, A, Delepierre, M, Tanguy, M and Tang, CM (2005). Optimization of virulence functions through glucosylation of Shigella LPS. Science, 307 (5713), 1313-1317. doi: 10.1126/science.1108472 |
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2003 Journal Article Finding your niche: what has been learnt from STM studies on GI colonizationWest, NP, Sansonetti, PJ, Frankel, G and Tang, CM (2003). Finding your niche: what has been learnt from STM studies on GI colonization. Trends in Microbiology, 11 (7), 338-344. doi: 10.1016/S0966-842X(03)00154-9 |
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2003 Journal Article An aromatic amino acid auxotrophic mutant of Bordetella bronchiseptica is attenuated and immunogenic in a mouse model of infectionMcArthur, JD, West, NP, Cole, JN, Jungnitz, H, Guzman, CA, Chin, J, Lehrbach, PR, Djordjevic, SP and Walker, MJ (2003). An aromatic amino acid auxotrophic mutant of Bordetella bronchiseptica is attenuated and immunogenic in a mouse model of infection. Fems Microbiology Letters, 221 (1), 7-16. doi: 10.1016/S0378-1097(03)00162-9 |
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2002 Journal Article High throughput in vivo screens: Signature-tagged mutagenesisWest, N, Sansonetti, P and Tang, CM (2002). High throughput in vivo screens: Signature-tagged mutagenesis. Functional Microbial Genomics, 33, 153-165. |
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2000 Journal Article Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulenceWest, Nicholas P., Jungnitz, Heidrun, Fitter, John T., McArthur, Jason D., Guzman, Carlos A. and Walker, Mark J. (2000). Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence. Infection and Immunity, 68 (8), 4673-4680. doi: 10.1128/IAI.68.8.4673-4680.2000 |
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1998 Journal Article A second two-component regulatory system of Bordetella bronchiseptica required for bacterial resistance to oxidative stress, production of acid phosphatase, and in vivo persistenceJungnitz, Heidrun, West, Nicholas P., Walker, Mark J., Chhatwal, Gursharan S. and Guzman, Carlos A. (1998). A second two-component regulatory system of Bordetella bronchiseptica required for bacterial resistance to oxidative stress, production of acid phosphatase, and in vivo persistence. Infection and Immunity, 66 (10), 4640-4650. |
