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2014

Journal Article

Preface

Gillam, Elizabeth M.J., Copp, Janine N. and Ackerley, David F. (2014). Preface. Methods in Molecular Biology, 1179.

Preface

2014

Conference Publication

Cyp2E1 and Cyp2U1 Protein Expression in Human Amygdala and Prefrontal Cortex: Influence of Alcoholism and Smoking

Toselli, Francesca, Worrall, Simon, Wilce, Peter A., Dodd, Peter R. and Gillam, Elizabeth M. J. (2014). Cyp2E1 and Cyp2U1 Protein Expression in Human Amygdala and Prefrontal Cortex: Influence of Alcoholism and Smoking. 10th International Meeting of the International Society for the Study of Xenobiotics (ISSX), Toronto, Canada, 29 September - 03 October 2013. New York, NY United States: Informa Healthcare.

Cyp2E1 and Cyp2U1 Protein Expression in Human Amygdala and Prefrontal Cortex: Influence of Alcoholism and Smoking

2014

Book

Directed Evolution Library Creation: methods and protocols

Elizabeth M.J. Gillam, Janine N. Copp and David F. Ackerley eds. (2014). Directed Evolution Library Creation: methods and protocols. 2nd ed. Methods in Molecular Biology, New York, NY United States: Springer. doi: 10.1007/978-1-4939-1053-3

Directed Evolution Library Creation: methods and protocols

2014

Book Chapter

Computational tools for directed evolution: a comparison of prospective and retrospective strategies

Zaugg, Julian, Gumulya, Yosephine, Gillam, Elizabeth M. J. and Bodén, Mikael (2014). Computational tools for directed evolution: a comparison of prospective and retrospective strategies. Directed evolution library creation: methods and protocols. (pp. 315-333) edited by Elizabeth M. J. Gillam, Janine N. Copp and David F. Ackerley. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1053-3_21

Computational tools for directed evolution: a comparison of prospective and retrospective strategies

2014

Book Chapter

Preface

Gillam, Elizabeth M. J., Copp, Janine N. and Ackerley, David F. (2014). Preface. Directed evolution library creation: methods and protocols. (pp. v-vi) edited by Elizabeth M.J. Gillam, Janine N. Copp and David Ackerley. New York, NY United States: Humana Press.

Preface

2013

Journal Article

The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development

Gillam, Elizabeth M. J. and Hayes, Martin A. (2013). The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development. Current Topics in Medicinal Chemistry, 13 (18), 2254-2280. doi: 10.2174/15680266113136660158

The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development

2013

Journal Article

Differential expression of human cytochrome P450 enzymes from the CYP3A subfamily in the brains of alcoholic subjects and drug-free controls

Depaz, Iris M. Booth, Toselli, Francesca, Wilce, Peter A. and Gillam, Elizabeth M. J. (2013). Differential expression of human cytochrome P450 enzymes from the CYP3A subfamily in the brains of alcoholic subjects and drug-free controls. Drug Metabolism and Disposition, 41 (6), 1187-1194. doi: 10.1124/dmd.113.051359

Differential expression of human cytochrome P450 enzymes from the CYP3A subfamily in the brains of alcoholic subjects and drug-free controls

2013

Journal Article

Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides

Cheesman, Matthew J., Traylor, Matthew. J., Hilton, Margaret E., Richards, Katelyn E., Taylor, Matthew C., Daborn, Philip J., Russell, Robyn J., Gillam, Elizabeth M. J. and Oakeshott, John G. (2013). Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides. Insect Biochemistry and Molecular Biology, 43 (5), 455-465. doi: 10.1016/j.ibmb.2013.02.003

Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides

2013

Book Chapter

DNA shuffling of cytochrome P450 enzymes

Behrendorff, James B. Y. H., Johnston, Wayne A. and Gillam, Elizabeth M. J. (2013). DNA shuffling of cytochrome P450 enzymes. Cytochrome P450 protocols. (pp. 177-188) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_16

DNA shuffling of cytochrome P450 enzymes

2013

Book Chapter

Measurement of P450 difference spectra using intact cells

Johnston, Wayne A. and Gillam, Elizabeth M. J. (2013). Measurement of P450 difference spectra using intact cells. Cytochrome P450 protocols. (pp. 189-204) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_17

Measurement of P450 difference spectra using intact cells

2012

Journal Article

Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli

Behrendorff, James B. Y. H., Moore, Chad D., Kim, Keon-Hee, Kim, Dae-Hwan, Smith, Christopher A., Johnston, Wayne A., Yun, Chui-Ho, Yost, Garold S. and Gillam, Elizabeth M. J. (2012). Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli. Chemical Research in Toxicology, 25 (9), 1964-1974. doi: 10.1021/tx300281g

Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli

2012

Conference Publication

Quantification of cytochromes P450, ABC transporters and their main transcription factors in the brains of alcoholics, smokers and drug-free controls by QRT-PCR

Toselli, Francesca, De Waziers, I., Wilce, P., Gillam, M. J. and Loriot, M. A. (2012). Quantification of cytochromes P450, ABC transporters and their main transcription factors in the brains of alcoholics, smokers and drug-free controls by QRT-PCR. 18th North American Regional International-Society-for-the-Study-of-Xenobiotics (ISSX) Meeting, Dallas, TX, United States, 14-18 October 2012. New York, NY, United States: Informa Healthcare. doi: 10.3109/03602532.2012.744573

Quantification of cytochromes P450, ABC transporters and their main transcription factors in the brains of alcoholics, smokers and drug-free controls by QRT-PCR

2012

Journal Article

Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry class

Rowland, Susan L., Lawrie, Gwen A., Behrendorff, James B. Y. H. and Gillam, Elizabeth M. J. (2012). Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry class. Biochemistry and Molecular Biology Education, 40 (1), 46-62. doi: 10.1002/bmb.20576

Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry class

2011

Journal Article

Cytochrome P450 is present in both ferrous and ferric forms in the resting state within intact Escherichia coli and hepatocytes

Johnston, Wayne A., Hunter, Dominic J. B., Noble, Christopher J., Hanson, Graeme R., Stok, Jeanette E., Hayes, Martin A., De Voss, James J. and Gillam, Elizabeth M.J. (2011). Cytochrome P450 is present in both ferrous and ferric forms in the resting state within intact Escherichia coli and hepatocytes. Journal of Biological Chemistry, 286 (47), 40750-40759. doi: 10.1074/jbc.M111.300871

Cytochrome P450 is present in both ferrous and ferric forms in the resting state within intact Escherichia coli and hepatocytes

2011

Journal Article

Facile production of minor metabolites for drug development using a CYP3A shuffled library

Hunter, D.J.B., Behrendorff, J.B.Y.H., Johnston, W.A., Hayes, P.Y., Huang, W., Bonn, B., Hayes, M.A., De Voss, J.J. and Gillam, E.M.J (2011). Facile production of minor metabolites for drug development using a CYP3A shuffled library. Metabolic Engineering, 13 (6), 682-693. doi: 10.1016/j.ymben.2011.09.001

Facile production of minor metabolites for drug development using a CYP3A shuffled library

2011

Journal Article

The concept lens diagram: A new mechanism for presenting biochemistry content in terms of "big ideas"

Rowland, Susan L., Smith, Christopher A., Gillam, Elizabeth M. A. and Wright, Tony (2011). The concept lens diagram: A new mechanism for presenting biochemistry content in terms of "big ideas". Biochemistry and Molecular Biology Education, 39 (4), 267-279. doi: 10.1002/bmb.20517

The concept lens diagram: A new mechanism for presenting biochemistry content in terms of "big ideas"

2010

Journal Article

Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes

Toselli, F, Matthias, A, Bone, KM, Gillam, EMJ and Lehmann, RP (2010). Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes. Phytotherapy Research, 24 (8), 1195-1201. doi: 10.1002/ptr.3111

Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes

2010

Conference Publication

Rebuilding a generalist biochemistry course around core concepts rather than heavy content: Painting the big picture for a large mixed-learner cohort

Rowland, S., Gillam, E. M. J., Hamilton, S. E., Ramakrishna, M., Reid, A., Smith, C., Ward, L. C., Wood, I. and Wright, A. (2010). Rebuilding a generalist biochemistry course around core concepts rather than heavy content: Painting the big picture for a large mixed-learner cohort. 21st Biennial Conference on Chemistry Education, Denton, TX, U.S.A., 1-5 August 2010.

Rebuilding a generalist biochemistry course around core concepts rather than heavy content: Painting the big picture for a large mixed-learner cohort

2010

Book Chapter

Directed evolution of enzymes

Jackson, Colin J., Gillam, Elizabeth M. J. and Ollis, David L. (2010). Directed evolution of enzymes. Comprehensive natural products II chemistry and biology. (pp. 723-749) edited by Lewis Mander and Hung-Wen Liu. Oxford, England, Unied Kingdom: Elsevier.

Directed evolution of enzymes

2009

Journal Article

In silico characterization of protein chimeras: Relating sequence and function within the same fold

Buske, Fabian A., Their, Ricarda, Gillam, Elizabeth M. J. and Boden, Mikael (2009). In silico characterization of protein chimeras: Relating sequence and function within the same fold. Proteins: Structure, Function, and Bioinformatics, 77 (1), 111-120. doi: 10.1002/prot.22422

In silico characterization of protein chimeras: Relating sequence and function within the same fold