2014 Journal Article PrefaceGillam, Elizabeth M.J., Copp, Janine N. and Ackerley, David F. (2014). Preface. Methods in Molecular Biology, 1179. |
2014 Conference Publication Cyp2E1 and Cyp2U1 Protein Expression in Human Amygdala and Prefrontal Cortex: Influence of Alcoholism and SmokingToselli, Francesca, Worrall, Simon, Wilce, Peter A., Dodd, Peter R. and Gillam, Elizabeth M. J. (2014). Cyp2E1 and Cyp2U1 Protein Expression in Human Amygdala and Prefrontal Cortex: Influence of Alcoholism and Smoking. 10th International Meeting of the International Society for the Study of Xenobiotics (ISSX), Toronto, Canada, 29 September - 03 October 2013. New York, NY United States: Informa Healthcare. |
2014 Book Directed Evolution Library Creation: methods and protocolsElizabeth M.J. Gillam, Janine N. Copp and David F. Ackerley eds. (2014). Directed Evolution Library Creation: methods and protocols. 2nd ed. Methods in Molecular Biology, New York, NY United States: Springer. doi: 10.1007/978-1-4939-1053-3 |
2014 Book Chapter Computational tools for directed evolution: a comparison of prospective and retrospective strategiesZaugg, Julian, Gumulya, Yosephine, Gillam, Elizabeth M. J. and Bodén, Mikael (2014). Computational tools for directed evolution: a comparison of prospective and retrospective strategies. Directed evolution library creation: methods and protocols. (pp. 315-333) edited by Elizabeth M. J. Gillam, Janine N. Copp and David F. Ackerley. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1053-3_21 |
2014 Book Chapter PrefaceGillam, Elizabeth M. J., Copp, Janine N. and Ackerley, David F. (2014). Preface. Directed evolution library creation: methods and protocols. (pp. v-vi) edited by Elizabeth M.J. Gillam, Janine N. Copp and David Ackerley. New York, NY United States: Humana Press. |
2013 Journal Article The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and developmentGillam, Elizabeth M. J. and Hayes, Martin A. (2013). The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development. Current Topics in Medicinal Chemistry, 13 (18), 2254-2280. doi: 10.2174/15680266113136660158 |
2013 Journal Article Differential expression of human cytochrome P450 enzymes from the CYP3A subfamily in the brains of alcoholic subjects and drug-free controlsDepaz, Iris M. Booth, Toselli, Francesca, Wilce, Peter A. and Gillam, Elizabeth M. J. (2013). Differential expression of human cytochrome P450 enzymes from the CYP3A subfamily in the brains of alcoholic subjects and drug-free controls. Drug Metabolism and Disposition, 41 (6), 1187-1194. doi: 10.1124/dmd.113.051359 |
2013 Journal Article Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticidesCheesman, Matthew J., Traylor, Matthew. J., Hilton, Margaret E., Richards, Katelyn E., Taylor, Matthew C., Daborn, Philip J., Russell, Robyn J., Gillam, Elizabeth M. J. and Oakeshott, John G. (2013). Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides. Insect Biochemistry and Molecular Biology, 43 (5), 455-465. doi: 10.1016/j.ibmb.2013.02.003 |
2013 Book Chapter DNA shuffling of cytochrome P450 enzymesBehrendorff, James B. Y. H., Johnston, Wayne A. and Gillam, Elizabeth M. J. (2013). DNA shuffling of cytochrome P450 enzymes. Cytochrome P450 protocols. (pp. 177-188) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_16 |
2013 Book Chapter Measurement of P450 difference spectra using intact cellsJohnston, Wayne A. and Gillam, Elizabeth M. J. (2013). Measurement of P450 difference spectra using intact cells. Cytochrome P450 protocols. (pp. 189-204) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_17 |
2012 Journal Article Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coliBehrendorff, James B. Y. H., Moore, Chad D., Kim, Keon-Hee, Kim, Dae-Hwan, Smith, Christopher A., Johnston, Wayne A., Yun, Chui-Ho, Yost, Garold S. and Gillam, Elizabeth M. J. (2012). Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli. Chemical Research in Toxicology, 25 (9), 1964-1974. doi: 10.1021/tx300281g |
2012 Conference Publication Quantification of cytochromes P450, ABC transporters and their main transcription factors in the brains of alcoholics, smokers and drug-free controls by QRT-PCRToselli, Francesca, De Waziers, I., Wilce, P., Gillam, M. J. and Loriot, M. A. (2012). Quantification of cytochromes P450, ABC transporters and their main transcription factors in the brains of alcoholics, smokers and drug-free controls by QRT-PCR. 18th North American Regional International-Society-for-the-Study-of-Xenobiotics (ISSX) Meeting, Dallas, TX, United States, 14-18 October 2012. New York, NY, United States: Informa Healthcare. doi: 10.3109/03602532.2012.744573 |
2012 Journal Article Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry classRowland, Susan L., Lawrie, Gwen A., Behrendorff, James B. Y. H. and Gillam, Elizabeth M. J. (2012). Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry class. Biochemistry and Molecular Biology Education, 40 (1), 46-62. doi: 10.1002/bmb.20576 |
2011 Journal Article Cytochrome P450 is present in both ferrous and ferric forms in the resting state within intact Escherichia coli and hepatocytesJohnston, Wayne A., Hunter, Dominic J. B., Noble, Christopher J., Hanson, Graeme R., Stok, Jeanette E., Hayes, Martin A., De Voss, James J. and Gillam, Elizabeth M.J. (2011). Cytochrome P450 is present in both ferrous and ferric forms in the resting state within intact Escherichia coli and hepatocytes. Journal of Biological Chemistry, 286 (47), 40750-40759. doi: 10.1074/jbc.M111.300871 |
2011 Journal Article Facile production of minor metabolites for drug development using a CYP3A shuffled libraryHunter, D.J.B., Behrendorff, J.B.Y.H., Johnston, W.A., Hayes, P.Y., Huang, W., Bonn, B., Hayes, M.A., De Voss, J.J. and Gillam, E.M.J (2011). Facile production of minor metabolites for drug development using a CYP3A shuffled library. Metabolic Engineering, 13 (6), 682-693. doi: 10.1016/j.ymben.2011.09.001 |
2011 Journal Article The concept lens diagram: A new mechanism for presenting biochemistry content in terms of "big ideas"Rowland, Susan L., Smith, Christopher A., Gillam, Elizabeth M. A. and Wright, Tony (2011). The concept lens diagram: A new mechanism for presenting biochemistry content in terms of "big ideas". Biochemistry and Molecular Biology Education, 39 (4), 267-279. doi: 10.1002/bmb.20517 |
2010 Journal Article Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomesToselli, F, Matthias, A, Bone, KM, Gillam, EMJ and Lehmann, RP (2010). Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes. Phytotherapy Research, 24 (8), 1195-1201. doi: 10.1002/ptr.3111 |
2010 Conference Publication Rebuilding a generalist biochemistry course around core concepts rather than heavy content: Painting the big picture for a large mixed-learner cohortRowland, S., Gillam, E. M. J., Hamilton, S. E., Ramakrishna, M., Reid, A., Smith, C., Ward, L. C., Wood, I. and Wright, A. (2010). Rebuilding a generalist biochemistry course around core concepts rather than heavy content: Painting the big picture for a large mixed-learner cohort. 21st Biennial Conference on Chemistry Education, Denton, TX, U.S.A., 1-5 August 2010. |
2010 Book Chapter Directed evolution of enzymesJackson, Colin J., Gillam, Elizabeth M. J. and Ollis, David L. (2010). Directed evolution of enzymes. Comprehensive natural products II chemistry and biology. (pp. 723-749) edited by Lewis Mander and Hung-Wen Liu. Oxford, England, Unied Kingdom: Elsevier. |
2009 Journal Article In silico characterization of protein chimeras: Relating sequence and function within the same foldBuske, Fabian A., Their, Ricarda, Gillam, Elizabeth M. J. and Boden, Mikael (2009). In silico characterization of protein chimeras: Relating sequence and function within the same fold. Proteins: Structure, Function, and Bioinformatics, 77 (1), 111-120. doi: 10.1002/prot.22422 |