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2009 Journal Article Membrane integration of recombinant human P450 formsShukla, A., Huang, W., Depaz, I. M. and Gillam, E. M. J. (2009). Membrane integration of recombinant human P450 forms. Xenobiotica, 39 (7), 495-507. doi: 10.1080/00498250902934884 |
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2009 Journal Article Echinacea metabolism and drug interactions: The case for standardization of a complementary medicineToselli, F., Matthias, A. and Gillam, E. M. J. (2009). Echinacea metabolism and drug interactions: The case for standardization of a complementary medicine. Life Sciences, 85 (3-4), 97-106. doi: 10.1016/j.lfs.2009.04.023 |
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2008 Journal Article Re-engineering of CYP2C9 to probe acid-base substrate selectivityTai, Guoying, Dickmann, Leslie J., Matovic, Nicholas, DeVoss, James J., Gillam, Elizabeth M. J. and Rettie, Allan E. (2008). Re-engineering of CYP2C9 to probe acid-base substrate selectivity. Drug Metabolism and Disposition, 36 (10), 1992-1997. doi: 10.1124/dmd.108.022186 |
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2008 Journal Article Quantitative whole-cell cytochrome P450 measurement suitable for high-throughput applicationJohnston, Wayne A., Huang, Weiliang, De Voss, James J., Hayes, Martin A. and Gillam, Elizabeth M.J. (2008). Quantitative whole-cell cytochrome P450 measurement suitable for high-throughput application. Journal of Biomolecular Screening, 13 (2), 135-141. doi: 10.1177/1087057107312780 |
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2008 Journal Article Engineering cytochrome P450 enzymesGillam, E. M. J. (2008). Engineering cytochrome P450 enzymes. Chemical Research in Toxicology, 21 (1), 220-231. doi: 10.1021/tx7002849 |
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2008 Journal Article A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descentHo, M. K., Mwenifumbo, J. C., Zhao, B., Gillam, E. M. J. and Tyndale, R. F. (2008). A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent. Pharmacogenetics and Genomics, 18 (1), 67-75. doi: 10.1097/FPC.0b013e3282f3606e |
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2008 Conference Publication Metabolism of Echinacea alkamides by human recombinant P450 enzymesToselli, F., Matthias, A., Bone, K. M., Gillam, E. M. J. and Lehmann, R. P. (2008). Metabolism of Echinacea alkamides by human recombinant P450 enzymes. 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, 3-8 August, 2008. Stuttgart, Germany: Thieme. doi: 10.1055/s-0028-1083940 |
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2007 Journal Article Chemical defense and exploitation, biotransformation of xenobiotics by cytochrome P450 enzymesGillam, Elizabeth M. J. and Hunter, Dominic J. B. (2007). Chemical defense and exploitation, biotransformation of xenobiotics by cytochrome P450 enzymes. Metal Ions in Life Sciences, 3, 477-560. |
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2007 Journal Article A shuffled CYP1A library shows both structural integrity and functional diversityJohnston, Wayne A., Huang, Weiliang, De Voss, James J., Hayes, Martin A. and Gillam, Elizabeth M.J. (2007). A shuffled CYP1A library shows both structural integrity and functional diversity. Drug Metabolism And Disposition, 35 (12), 2177-2185. doi: 10.1124/dmd.107.017939 |
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2007 Journal Article A shuffled CYP2C library with a high degree of structural integrity and functional versatilityHuang, Weiliang, Johnston, Wayne A., Hayes, Martin A., De Voss, James J. and Gillam, Elizabeth M.J. (2007). A shuffled CYP2C library with a high degree of structural integrity and functional versatility. Archives of Biochemistry And Biophysics, 467 (2), 193-205. doi: 10.1016/j.abb.2007.08.023 |
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2007 Journal Article Extending the diversity of cytochrome P450 enzymes by DNA family shufflingRosic, Nedeljka N., Huang, Weiliang, Johnston, Wayne A., DeVoss, James J. and Gillam, Elizabeth M.J. (2007). Extending the diversity of cytochrome P450 enzymes by DNA family shuffling. Gene, 395 (1-2), 40-48. doi: 10.1016/j.gene.2007.01.031 |
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2007 Journal Article Formation of the indigo precursor indican in genetically engineered tobacco plants and cell culturesWarzecha, H, Frank, A, Peer, M, Gillam, EMJ, Guengerich, FP and Unger, M (2007). Formation of the indigo precursor indican in genetically engineered tobacco plants and cell cultures. Plant Biotechnology Journal, 5 (1), 185-191. doi: 10.1111/j.1467-7652.2006.00231.x |
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2007 Book Chapter Chemical Defence and Exploitation: Biotransformation of Xenobiotics by Cytochrome P450 EnzymesGillam, E. M. J. and Hunter, D. J. B. (2007). Chemical Defence and Exploitation: Biotransformation of Xenobiotics by Cytochrome P450 Enzymes. Metal Ions in Life Sciences. (pp. 477-560) edited by Astrid Sigel, Helmut Sigel and Roland K. O. Sigel. West Sussex: John Wiley and sons. doi: 10.1002/9780470028155.ch15 |
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2007 Journal Article Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide eliminationElliot, DJ, Suharjono, Lewis, BC, Gillam, EMJ, Birkett, DJ, Gross, AS and Miners, JO (2007). Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination. British Journal of Clinical Pharmacology, 64 (4), 450-457. doi: 10.1111/j.1365-2125.2007.02943.x |
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2007 Journal Article Extending the capabilities of nature's most versatile catalysts: Directed evolution of mammalian xenobiotic-metabolizing P450sGillam, EMJ (2007). Extending the capabilities of nature's most versatile catalysts: Directed evolution of mammalian xenobiotic-metabolizing P450s. Archives of Biochemistry And Biophysics, 464 (2), 176-186. doi: 10.1016/j.abb.2007.04.033 |
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2006 Journal Article Direct electrochemistry of human and rat NADPH cytochrome P450 reductaseShukla, Alka, Gillam, Elizabeth M. J. and Bernhardt, Paul V. (2006). Direct electrochemistry of human and rat NADPH cytochrome P450 reductase. Electrochemistry Communications, 8 (12), 1845-1849. doi: 10.1016/j.elecom.2006.08.020 |
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2006 Journal Article Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolitesAvent, Kathryn M., DeVoss, J. J. and Gillam, Elizabeth M. J. (2006). Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. Chemical Research In Toxicology, 19 (7), 914-920. doi: 10.1021/tx0600090 |
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2006 Conference Publication Dna family shuffling of mammalian P450s from CYP2A and CYP3A subfamiliesGillam, Elizabeth M. J., Johnston, W. A., DeVoss, J. J., Soucek, Pavel and Hunter, D. J. B. (2006). Dna family shuffling of mammalian P450s from CYP2A and CYP3A subfamilies. 14th North American Meeting of the International-Society-for-the-Study-of-Xenobiotics, Rio Grande, Puerto Rico, 22-26 October 2006. Philadelphia, PA USA: Taylor & Francis. |
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2006 Journal Article An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazidPolasek, TM, Elliot, DJ, Somogyi, AA, Gillam, EMJ, Lewis, BC and Miners, JO (2006). An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid. British Journal of Clinical Pharmacology, 61 (5), 570-584. doi: 10.1111/j.1365-2125.2006.02627.x |
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2006 Journal Article STAR: predicting recombination sites from amino acid sequenceBauer, Denis C., Boden, Mikael, Thier, Ricarda and Gillam, Elizabeth M. (2006). STAR: predicting recombination sites from amino acid sequence. BMC Bioinformatics, 7 (437) 437, 437. doi: 10.1186/1471-2105-7-437 |
