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1998 Conference Publication Expression of human cytochrome P4501B1 in bacteriaGuengerich, FP, Shimada, T, Gillam, EMJ, Sutter, TR and Wunsch, RM (1998). Expression of human cytochrome P4501B1 in bacteria. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1998 Conference Publication Analysis of cytochrome P450 2D6 : substrate interactions by site-directed mutagenesisHanna, IH, Gillam, EMJ and Guengerich, FP (1998). Analysis of cytochrome P450 2D6 : substrate interactions by site-directed mutagenesis. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1998 Journal Article Bacterial expression of two human aryl sulfotransferasesBidwell, L. M., Gillam, E. M. J., Gaedigk, A., Zhu, X., Grant, D. and McManus, M. E. (1998). Bacterial expression of two human aryl sulfotransferases. Chemico-biological Interactions, 109 (1-3), 137-141. doi: 10.1016/S0009-2797(97)00128-2 |
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1997 Journal Article Expression of cytochrome P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductaseGillam, EMJ, Wunsch, RM, Ueng, YF, Shimada, T, Reilly, PEB, Kamataki, T and Guengerich, FP (1997). Expression of cytochrome P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductase. Archives of Biochemistry and Biophysics, 346 (1), 81-90. doi: 10.1006/abbi.1997.0286 |
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1997 Journal Article Bioactivation of Phenytoin by Human Cytochrome P450: Characterization of the Mechanism and Targets of Covalent Adduct FormationMunns, Andrew J., De Voss, James J., Hooper, Wayne D., Dickinson, Ronald G. and Gillam, Elizabeth M. J. (1997). Bioactivation of Phenytoin by Human Cytochrome P450: Characterization of the Mechanism and Targets of Covalent Adduct Formation. Chemical Research In Toxicology, 10 (9), 1049-1058. doi: 10.1021/tx9700836 |
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1997 Journal Article Drug metabolism by Escherichia coli expressing human cytochromes P450Parikh, A, Gillam, EMJ and Guengerich, FP (1997). Drug metabolism by Escherichia coli expressing human cytochromes P450. Nature Biotechnology, 15 (8), 784-788. doi: 10.1038/nbt0897-784 |
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1997 Conference Publication Comparison of reconstitution conditions for recombinant human P450 2C9 with systems containing P450S 1A1, 1A2, 2D6, 2E1, and 3A4. Effects of P450-P450 and P450-b(5) interactionsYamazaki, H, Gillam, EMJ, Dong, MS, Johnson, WW, Guengerich, FP and Shimada, T (1997). Comparison of reconstitution conditions for recombinant human P450 2C9 with systems containing P450S 1A1, 1A2, 2D6, 2E1, and 3A4. Effects of P450-P450 and P450-b(5) interactions. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1997 Conference Publication Expression of P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of the recombinant enzymeGillam, EMJ, Wunsch, RM, Ueng, YF, Shimada, T, Parikh, A, Kamataki, T and Guengerich, FP (1997). Expression of P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of the recombinant enzyme. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1997 Journal Article Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: Effects of cytochrome P450-P450 and cytochrome P450-b5 interactionsYamazaki, H, Gillam, EMJ, Dong, MS, Johnson, WW, Guengerich, FP and Shimada, T (1997). Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: Effects of cytochrome P450-P450 and cytochrome P450-b5 interactions. Archives of Biochemistry and Biophysics, 342 (2), 329-337. doi: 10.1006/abbi.1997.0125 |
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1997 Journal Article Oxidation of xenobiotics by recombinant human cytochrome P450 1B1Shimada, T., Gillam, E. M. J., Sutter, T. R., Strickland, P. T., Guengerich, F. P. and Yamazaki, H. (1997). Oxidation of xenobiotics by recombinant human cytochrome P450 1B1. Drug Metabolism and Disposition, 25 (5), 617-622. |
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1996 Journal Article Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomesYamazaki, H, Nakano, M, Gillam, EMJ, Bell, LC, Guengerich, FP and Shimada, T (1996). Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes. Biochemical Pharmacology, 52 (2), 301-309. doi: 10.1016/0006-2952(96)00208-0 |
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1996 Journal Article New applications of bacterial systems to problems in toxicologyGuengerich, FP, Gillam, EMJ and Shimada, T (1996). New applications of bacterial systems to problems in toxicology. Critical Reviews in Toxicology, 26 (5), 551-583. doi: 10.3109/10408449609037477 |
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1995 Journal Article Expression of Cytochrome P450 2D6 in Escherichia coli, Purification, and Spectral and Catalytic CharacterizationGillam, Emj, Guo, ZY, Martin, MV, Jenkins, CM and Guengerich, FP (1995). Expression of Cytochrome P450 2D6 in Escherichia coli, Purification, and Spectral and Catalytic Characterization. Archives of Biochemistry and Biophysics, 319 (2), 540-550. doi: 10.1006/abbi.1995.1329 |
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1995 Journal Article Expression of Cytochrome-P450-3A5 in Escherichia-Coli - Effects of 5' Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities (Vol 317, Pg 374, 1995)Gillam, Emj, Guo, ZY, Ueng, YF, Yamazaki, H, Cock, I, Reilly, Peb, Hooper, WD and Guengerich, FP (1995). Expression of Cytochrome-P450-3A5 in Escherichia-Coli - Effects of 5' Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities (Vol 317, Pg 374, 1995). Archives of Biochemistry and Biophysics, 318 (2), 498-498. doi: 10.1006/abbi.1995.1259 |
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1995 Conference Publication Retention of N-Formylmethionine in Recombinant Bacterial Cytochrome-P450 Enzymes Containing the N-Terminal Sequence MalllavflDong, MS, Guo, Z, Philips, DR, Bell, LC, Howard, E, Blair, IA, Gillam, Emj, Baba, T, Waterman, MR and Guengerich, FP (1995). Retention of N-Formylmethionine in Recombinant Bacterial Cytochrome-P450 Enzymes Containing the N-Terminal Sequence Malllavfl. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1995 Journal Article Expression of cytochrome-p450-3a5 in escherichia coli: Effects of 5′ modification, purification, spectral characterization, reconstitution conditions, and catalytic activitiesGillam, Elizabeth M. J., Guo, Zuyu, Ueng, Yune-Fang, Yamazaki, Hiroshi, Cock, Ian, Reilly, Paul E. B., Hooper, Wayne D. and Guengerich, F. Peter (1995). Expression of cytochrome-p450-3a5 in escherichia coli: Effects of 5′ modification, purification, spectral characterization, reconstitution conditions, and catalytic activities. Archives of Biochemistry and Biophysics, 317 (2), 374-384. doi: 10.1006/abbi.1995.1177 |
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1994 Journal Article Activation of Procarcinogens by Human Cytochrome-P450 Enzymes Expressed in Escherichia-Coli - Simplified Bacterial Systems for Genotoxicity AssaysShimada, T, Gillam, Emj, Sandhu, P, Guo, ZY, Tukey, RH and Guengerich, FP (1994). Activation of Procarcinogens by Human Cytochrome-P450 Enzymes Expressed in Escherichia-Coli - Simplified Bacterial Systems for Genotoxicity Assays. Carcinogenesis, 15 (11), 2523-2529. doi: 10.1093/carcin/15.11.2523 |
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1994 Conference Publication Expression and Purification of Human Cytochrome-P450 Enzymes From Escherichia-ColiGuo, Z, Sandhu, P, Gillam, Emj, Martin, MV and Guengerich, FP (1994). Expression and Purification of Human Cytochrome-P450 Enzymes From Escherichia-Coli. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1994 Journal Article Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic propertiesGillam, Emj, Guo, ZY and Guengerich, FP (1994). Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties. Archives of Biochemistry and Biophysics, 312 (1), 59-66. doi: 10.1006/abbi.1994.1280 |
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1994 Conference Publication Mechanisms of Enhancement and Inhibition of Cytochrome-P450 Catalytic ActivitiesGuengerich, FP, Kim, BR, Gillam, Emj and Shimada, T (1994). Mechanisms of Enhancement and Inhibition of Cytochrome-P450 Catalytic Activities. 8th International Conference on Cytochrome P450: Biochemistry, Biophysics and Molecular Biology, Lisbon Portugal, Oct 24-28, 1993. MONTROUGE: JOHN LIBBEY EUROTEXT LTD. |
