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1994

Journal Article

Expression of modified human cytochrome P450 1A1 in Escherichia coli: Effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties

Guo, ZY, Gillam, Emj, Ohmori, S, Tukey, RH and Guengerich, FP (1994). Expression of modified human cytochrome P450 1A1 in Escherichia coli: Effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties. Archives of Biochemistry and Biophysics, 312 (2), 436-446. doi: 10.1006/abbi.1994.1330

Expression of modified human cytochrome P450 1A1 in Escherichia coli: Effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties

1993

Journal Article

Expression of human cytochrome P450 enzymes in yeast and bacteria and relevance to studies on catalytic specificity

Guengerich, FP, Gillam, Emj, Ohmori, S, Sandhu, P, Brian, WR, Sari, MA and Iwasaki, M (1993). Expression of human cytochrome P450 enzymes in yeast and bacteria and relevance to studies on catalytic specificity. Toxicology, 82 (1-3), 21-37. doi: 10.1016/0300-483X(93)90057-Y

Expression of human cytochrome P450 enzymes in yeast and bacteria and relevance to studies on catalytic specificity

1993

Journal Article

EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450 3A4 IN ESCHERICHIA-COLI AND PURIFICATION AND RECONSTITUTION OF THE ENZYME

GILLAM, EMJ, BABA, T, KIM, BR, OHMORI, S and GUENGERICH, FP (1993). EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450 3A4 IN ESCHERICHIA-COLI AND PURIFICATION AND RECONSTITUTION OF THE ENZYME. Archives of Biochemistry and Biophysics, 305 (1), 123-131. doi: 10.1006/abbi.1993.1401

EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450 3A4 IN ESCHERICHIA-COLI AND PURIFICATION AND RECONSTITUTION OF THE ENZYME

1993

Conference Publication

3-Alpha-Hydroxylation and 8,9-Epoxidation of Aflatoxin-B(1) by Cytochrome-P450-3A4 - Evidence for Allosteric Behavior in Microsomal-Membranes and a Recombinant Enzyme

Kim, BR, Baba, T, Gillam, Emj and Guengerich, FP (1993). 3-Alpha-Hydroxylation and 8,9-Epoxidation of Aflatoxin-B(1) by Cytochrome-P450-3A4 - Evidence for Allosteric Behavior in Microsomal-Membranes and a Recombinant Enzyme. BETHESDA: FEDERATION AMER SOC EXP BIOL.

3-Alpha-Hydroxylation and 8,9-Epoxidation of Aflatoxin-B(1) by Cytochrome-P450-3A4 - Evidence for Allosteric Behavior in Microsomal-Membranes and a Recombinant Enzyme

1993

Conference Publication

Expression of Human Cytochrome-P450 Enzymes in Escherichia-Coli, Purification, and Reconstitution of Catalytic Activity

Sandhu, P, Gillam, Emj, Baba, T, Kim, BR and Guengerich, FP (1993). Expression of Human Cytochrome-P450 Enzymes in Escherichia-Coli, Purification, and Reconstitution of Catalytic Activity. BETHESDA: FEDERATION AMER SOC EXP BIOL.

Expression of Human Cytochrome-P450 Enzymes in Escherichia-Coli, Purification, and Reconstitution of Catalytic Activity

1992

Conference Publication

Expression of Human Cytochrome-P-450-3A4 and Cytochrome-P450-2E1 in the Bacterium Escherichia-Coli

Gillam, Emj, Omori, S, Sandhu, P and Guengerich, FP (1992). Expression of Human Cytochrome-P-450-3A4 and Cytochrome-P450-2E1 in the Bacterium Escherichia-Coli. BETHESDA: FEDERATION AMER SOC EXP BIOL.

Expression of Human Cytochrome-P-450-3A4 and Cytochrome-P450-2E1 in the Bacterium Escherichia-Coli

1991

Conference Publication

Spectral Studies Investigating the Binding of Cyclosporine-A to Hepatic Cytochromes-P450

Gillam, Emj and Harvey, DJ (1991). Spectral Studies Investigating the Binding of Cyclosporine-A to Hepatic Cytochromes-P450. 4Th International Symp On the Biological Oxidation of Nitrogen in Organic Molecules, Munich Fed Rep Ger, Sep 17-21, 1989. STUTTGART: GUSTAV FISCHER VERLAG.

Spectral Studies Investigating the Binding of Cyclosporine-A to Hepatic Cytochromes-P450

1990

Journal Article

Propranolol Oxidation by Human Liver-Microsomes - the Use of Cumene Hydroperoxide to Probe Isoenzyme Specificity and Regioselectivity and Stereoselectivity

Otton, SV, Gillam, Emj, Lennard, MS, Tucker, GT and Woods, HF (1990). Propranolol Oxidation by Human Liver-Microsomes - the Use of Cumene Hydroperoxide to Probe Isoenzyme Specificity and Regioselectivity and Stereoselectivity. British Journal of Clinical Pharmacology, 30 (5), 751-760. doi: 10.1111/j.1365-2125.1990.tb03846.x

Propranolol Oxidation by Human Liver-Microsomes - the Use of Cumene Hydroperoxide to Probe Isoenzyme Specificity and Regioselectivity and Stereoselectivity

1990

Journal Article

Immunotoxic Side-Effects of Drug Therapy

Mitchell, JA, Gillam, Emj, Stanley, LA and Sim, E (1990). Immunotoxic Side-Effects of Drug Therapy. Drug Safety, 5 (3), 168-178. doi: 10.2165/00002018-199005030-00002

Immunotoxic Side-Effects of Drug Therapy

1988

Journal Article

Differential Inhibition of Human-Liver Phenacetin O-Deethylation by Histamine and 4 Histamine H-2-Receptor Antagonists

Reilly, Peb, Mason, SR and Gillam, Emj (1988). Differential Inhibition of Human-Liver Phenacetin O-Deethylation by Histamine and 4 Histamine H-2-Receptor Antagonists. Xenobiotica, 18 (4), 381-387.

Differential Inhibition of Human-Liver Phenacetin O-Deethylation by Histamine and 4 Histamine H-2-Receptor Antagonists

1988

Journal Article

Phenacetin o-deethylation by human liver microsomes: Kinetics and propranolol inhibition

Gillam, Elizabeth M. J. and Reilly, Paul E. B. (1988). Phenacetin o-deethylation by human liver microsomes: Kinetics and propranolol inhibition. Xenobiotica, 18 (1), 95-104. doi: 10.3109/00498258809055140

Phenacetin o-deethylation by human liver microsomes: Kinetics and propranolol inhibition

1988

Journal Article

Phenacetin O-Deethylation by Human-Liver Microsomes - Kinetics and Propranolol Inhibition

Gillam, Emj and Reilly, Peb (1988). Phenacetin O-Deethylation by Human-Liver Microsomes - Kinetics and Propranolol Inhibition. Xenobiotica, 18 (1), 95-104.

Phenacetin O-Deethylation by Human-Liver Microsomes - Kinetics and Propranolol Inhibition

1988

Journal Article

Differential inhibition of human liver phenacetin o-deethylation by histamine and four histamine h2-receptor antagonists

Reilly, P. E B, Mason, S. R. and Gillam, E. M J (1988). Differential inhibition of human liver phenacetin o-deethylation by histamine and four histamine h2-receptor antagonists. Xenobiotica, 18 (4), 381-387. doi: 10.3109/00498258809041674

Differential inhibition of human liver phenacetin o-deethylation by histamine and four histamine h2-receptor antagonists

1987

Journal Article

Physical partitioning as the major source of metoprolol uptake by hepatic microsomes

Bogeyevitch, MA, Gillam, Emj, Reilly, Peb and Winzor, DJ (1987). Physical partitioning as the major source of metoprolol uptake by hepatic microsomes. Biochemical Pharmacology, 36 (23), 4167-4168. doi: 10.1016/0006-2952(87)90576-4

Physical partitioning as the major source of metoprolol uptake by hepatic microsomes

1986

Journal Article

Cellular-Energy Charge in the Heart and Liver of the Rat - the Effects of Ethanol and Acetaldehyde

Gillam, E and Ward, LC (1986). Cellular-Energy Charge in the Heart and Liver of the Rat - the Effects of Ethanol and Acetaldehyde. International Journal of Biochemistry, 18 (11), 1031-1038. doi: 10.1016/0020-711X(86)90249-1

Cellular-Energy Charge in the Heart and Liver of the Rat - the Effects of Ethanol and Acetaldehyde