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2010

Journal Article

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme

Foo, Jee‑Loon, Jackson, Colin J., Carr, Paul D., Kim, Hye‑Kyung, Schenk, Gerhard, Gahan, Lawrence R. and Ollis, David L. (2010). Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochemical Journal, 429 (2), 313-321. doi: 10.1042/BJ20100233

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme

2010

Journal Article

The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis

Mitic, Natasa, Hadler, Kieran S., Gahan, Lawrence R., Hengge, Alvan C. and Schenk, Gerhard (2010). The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. Journal of the American Chemical Society, 132 (20), 7049-7054. doi: 10.1021/ja910583y

The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis

2010

Journal Article

Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes

Hadler, Kieran S., Mitic, Natasa, Yip, Sylvia Hsu-Chen, Gahan, Lawrence R., Ollis, David L., Schenk, Gerhard and Larrabee, James A. (2010). Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorganic Chemistry, 49 (6), 2727-2734. doi: 10.1021/ic901950c

Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes

2010

Conference Publication

Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR Spectroscopy

Noble, Christopher J., Gahan, Lawrence R., Schenk, Gerhard and Hanson, Graeme R. (2010). Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR Spectroscopy. World Wide Magnetic Resonance 2010: Joint Euromar 2010 and 17th ISMAR Conference (WWMR2010 ), Florence, Italy, 4-9 July 2010. Florence, Italy: Worldwide Magnetic Resonance Conference.

Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR Spectroscopy

2010

Journal Article

Catalytic promiscuity: Catecholase-like activity and hydrolytic DNA cleavage promoted by a mixed-valence Fe(III)Fe(II) complex

Neves, Ademir, Bortoluzzi, Adailton J., Jovito, Rafael, Peralta, Rosely A., de Souza, Bernardo, Szpoganicz, Bruno, Joussef, Antônio C., Terenzi, Hernán, Severino, Patricia C., Fischer, Franciele L., Schenk, Gerhard, Riley, Mark J., Smith, Sarah J. and Gahan, Lawrence R. (2010). Catalytic promiscuity: Catecholase-like activity and hydrolytic DNA cleavage promoted by a mixed-valence Fe(III)Fe(II) complex. Journal of the Brazilian Chemical Society, 21 (7), 1201-1212. doi: 10.1590/S0103-50532010000700007

Catalytic promiscuity: Catecholase-like activity and hydrolytic DNA cleavage promoted by a mixed-valence Fe(III)Fe(II) complex

2010

Book Chapter

Manganese Metalloproteins

Smith, Sarah J., Hadler, Kieran S., Schenk, Gerhard, Hanson, Graeme R. and Mitic, Nataša (2010). Manganese Metalloproteins. Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes. (pp. 273-341) edited by Graeme Hanson and Lawrence Berliner. New York, USA: Springer. doi: 10.1007/978-1-4419-1139-1_9

Manganese Metalloproteins

2010

Conference Publication

Metal ion mutagenesis – conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site

Mitic, Natasa, Noble, Christopher, Gahan, Lawrence R., Hanson, Graeme R. and Schenk, Gerhard (Gary) (2010). Metal ion mutagenesis – conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site. EPR 2010. A Joint Conference of the 14th In Vivo ESR/EPR Spectroscopy & Imaging and the 11th International EPR Spin Trapping/Spin Labeling, San Juan, Puerto Rico, 2-6 May 2010.

Metal ion mutagenesis – conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site

2010

Conference Publication

Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR spectroscopy

Noble, Christopher, Mitic, Natasa, Park, Ah Young, Gahan, Lawrence R., Schenk, Gerhard, Dixon, Nicholas E. and Hanson, Graeme R. (2010). Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR spectroscopy. 7th Asia-Pacific EPR/ESR Symposium (APES2010), Jeju Island, Republic of Korea, 10-14 October 2010. Daegu, Republic of Korea: Asia-Pacific EPR/ESR Society.

Insights into metal ion mutagenesis and catalysis of dinuclear Mn metallohydrolyases utilizing EPR spectroscopy

2009

Journal Article

Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

Jackson, C. J., Foo, J.-L., Tokuriki, N., Afriat, L., Carr, P. D., Kim, H.-K., Schenk, G., Tawfik, D. S. and Ollis, D. L. (2009). Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase. Proceedings of the National Academy of Sciences, 106 (51), 21631-21636. doi: 10.1073/pnas.0907548106

Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

2009

Journal Article

Flexible and promiscuous!

Schenk, G., Ollis, D. L., Hanson, G. R. and Gahan, L. R. (2009). Flexible and promiscuous!. Chemistry in Australia, 76 (10), 10-11.

Flexible and promiscuous!

2009

Journal Article

The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis

Hadler, Kieran S., Gahan, Lawrence R., Ollis, David L. and Schenk, Gerhard (2009). The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis. Journal of Inorganic Biochemistry, 104 (2), 211-213. doi: 10.1016/j.jinorgbio.2009.10.012

The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis

2009

Journal Article

Structural and catalytic characterization of a heterovalent Mn(II)Mn(III) complex that mimics purple acid phosphatases

Sarah Sarah J., Riley, Mark J., Noble, Christopher J., Hanson, Graeme R., Stranger, Robert, Jayaratne, Vidura, Cavigliasso, German, Schenk, Gerhard and Gahan, Lawrence R. (2009). Structural and catalytic characterization of a heterovalent Mn(II)Mn(III) complex that mimics purple acid phosphatases. Inorganic Chemistry, 48 (21), 10036-10048. doi: 10.1021/ic9005086

Structural and catalytic characterization of a heterovalent Mn(II)Mn(III) complex that mimics purple acid phosphatases

2009

Journal Article

Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis

Hadler, Kieran S., Mitic, Natasa, Ely, Fernanda, Hanson, Graeme R., Gahan, Lawrence R., Larrabee, James A., Ollis, David L. and Schenk, Gerhard (2009). Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis. Journal of the American Chemical Society, 131 (33), 11900-11908. doi: 10.1021/ja903534f

Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis

2009

Journal Article

Unsymmetrical FeIIICoIII and GaIIICoII complexes as chemical hydrolases: Biomimetic models for purple acid phosphatases (PAPs)

Xavier, Fernando R., Neves, Ademir, Casellato, Annelise, Peralta, Rosely A., Bortoluzzi, Adailton J., Szpoganicz, Bruno, Severino, Patricia C., Terenzi, Hernan, Tomkowicz, Zbigniew, Ostrovsky, Sergei, Haase, Wolfgang, Ozarowski, Andrew, Krzystek, Jerzy, Telser, Joshua, Schenk, Gerhard and Gahan, Lawrence R. (2009). Unsymmetrical FeIIICoIII and GaIIICoII complexes as chemical hydrolases: Biomimetic models for purple acid phosphatases (PAPs). Inorganic Chemistry, 48 (16), 7905-7921. doi: 10.1021/ic900831q

Unsymmetrical FeIIICoIII and GaIIICoII complexes as chemical hydrolases: Biomimetic models for purple acid phosphatases (PAPs)

2009

Journal Article

Metal-ion mutagenesis: Conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site

Mitić, Nataša, Noble, Christopher J., Gahan, Lawrence R., Hanson, Graeme R. and Schenk, Gerhard (2009). Metal-ion mutagenesis: Conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site. Journal of the American Chemical Society, 131 (23), 8173-8179. doi: 10.1021/ja900797u

Metal-ion mutagenesis: Conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent MnIIMnII active site

2009

Journal Article

Phosphate ester hydrolysis: Metal complexes as purple acid phosphatase and phosphotriesterase analogues

Gahan, Lawrence R., Smith, Sarah J., Neves, Ademir and Schenk, Gerhard (2009). Phosphate ester hydrolysis: Metal complexes as purple acid phosphatase and phosphotriesterase analogues. European Journal of Inorganic Chemistry, 2009 (19), 2745-2758. doi: 10.1002/ejic.200900231

Phosphate ester hydrolysis: Metal complexes as purple acid phosphatase and phosphotriesterase analogues

2009

Journal Article

Catalase vs peroxidase activity of a manganese(II) compound: Identification of a Mn(III)-(mu-O)(2)-Mn(IV) reaction intermediate by electrospray ionization mass spectrometry and electron paramagnetic resonance spectroscopy

Lessa, Josane A., Horn, Adolfo Jr., Bull, Érika S., Rocha, Michelle R., Benassi, Mario, Catharino, Rodrigo R., Eberlin, Marcos N., Casellato, Annelise, Noble, Christopher J., Hanson, Graeme R., Schenk, Gerhard, Silva, Giselle C., Antunes, O. A. C. and Fernandes, Christiane (2009). Catalase vs peroxidase activity of a manganese(II) compound: Identification of a Mn(III)-(mu-O)(2)-Mn(IV) reaction intermediate by electrospray ionization mass spectrometry and electron paramagnetic resonance spectroscopy. Inorganic Chemistry, 48 (10), 4569-4579. doi: 10.1021/ic801969c

Catalase vs peroxidase activity of a manganese(II) compound: Identification of a Mn(III)-(mu-O)(2)-Mn(IV) reaction intermediate by electrospray ionization mass spectrometry and electron paramagnetic resonance spectroscopy

2009

Journal Article

GpdQ: a clever enzymatic bioremediator

Schenk, Gerhard (2009). GpdQ: a clever enzymatic bioremediator. Chemistry in Australia, 76 (1), 32-33.

GpdQ: a clever enzymatic bioremediator

2009

Book Chapter

Binuclear non-heme iron enzymes

Mitić, Nataša, Schenk, Gerhard and Hanson, Graeme R. (2009). Binuclear non-heme iron enzymes. High resolution EPR: applications to metalloenzymes and metals in medicine. (pp. 269-395) edited by Graeme Hanson and Lawrence Berliner. New York, NY, United States: Springer. doi: 10.1007/978-0-387-84856-3_7

Binuclear non-heme iron enzymes

2009

Journal Article

Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids

McGeary, Ross P., Vella, Peter, Mak, Jeffery Y. W., Guddat, Luke W. and Schenk, Gerhard (2009). Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorganic & Medicinal Chemistry Letters, 19 (1), 163-166. doi: 10.1016/j.bmcl.2008.10.125

Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids