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2015

Journal Article

Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatases

Bosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Noble, Christopher, Schenk, Gerhard and Wadepohl, Hubert (2015). Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatases. Chemistry - A European Journal, 21 (50), 18269-18279. doi: 10.1002/chem.201503348

Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatases

2015

Journal Article

Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimetics

Larrabee, James A., Schenk, Gerhard, Mitic, Natasa and Riley, Mark J. (2015). Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimetics. European Biophysics Journal, 44 (6), 393-415. doi: 10.1007/s00249-015-1053-6

Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimetics

2015

Journal Article

An approach to more accurate model systems for purple acid phosphatases (PAPs)

Bernhardt, Paul V., Bosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Mereacre, Valeriu, Noble, Christopher J., Powell, Annie K., Schenk, Gerhard and Wadepohl, Hubert (2015). An approach to more accurate model systems for purple acid phosphatases (PAPs). Inorganic Chemistry, 54 (15), 7249-7263. doi: 10.1021/acs.inorgchem.5b00628

An approach to more accurate model systems for purple acid phosphatases (PAPs)

2015

Journal Article

A Heterodinuclear Fe<sup>III</sup>Zn<sup>II</sup> Complex as a Mimic for Purple Acid Phosphatase with Site-Specific Zn<sup>II</sup> Binding

Roberts, Asha E, Schenk, Gerhard and Gahan, Lawrence R (2015). A Heterodinuclear FeIIIZnII Complex as a Mimic for Purple Acid Phosphatase with Site-Specific ZnII Binding. European Journal of Inorganic Chemistry, 2015 (19), 3076-3086. doi: 10.1002/ejic.201500351

A Heterodinuclear Fe<sup>III</sup>Zn<sup>II</sup> Complex as a Mimic for Purple Acid Phosphatase with Site-Specific Zn<sup>II</sup> Binding

2015

Journal Article

Altering the substrate specificity of methyl parathion hydrolase with directed evolution

Ng, Tee-Kheang, Gahan, Lawrence R., Schenk, Gerhard and Ollis, David L. (2015). Altering the substrate specificity of methyl parathion hydrolase with directed evolution. Archives of Biochemistry and Biophysics, 573, 59-68. doi: 10.1016/j.abb.2015.03.012.

Altering the substrate specificity of methyl parathion hydrolase with directed evolution

2015

Journal Article

Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ions

Quiñones, Matías, Cofre, Jaime, Benítez, José, García, David, Romero, Nicol, González, Arlette, Carvajal, Nelson, García, María, López, Vasthi, Schenk, Gerhard and Uribe, Elena (2015). Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ions. Journal of Inorganic Biochemistry, 145, 65-69. doi: 10.1016/j.jinorgbio.2015.01.008

Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ions

2015

Journal Article

Inteins—A focus on the biotechnological applications of splicing-promoting proteins

Miraula, Manfredi, Enculescu, Charmaine, Schenk, Gerhard and Mitić, Nataša (2015). Inteins—A focus on the biotechnological applications of splicing-promoting proteins. American Journal of Molecular Biology, 05 (02), 42-56. doi: 10.4236/ajmb.2015.52005

Inteins—A focus on the biotechnological applications of splicing-promoting proteins

2015

Journal Article

β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health

Miraula, Manfredi, Whitaker, Jacob J, Schenk, Gerhard and Mitic, Natasa (2015). β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health. Journal of Biological Inorganic Chemistry, 20 (4), 639-651. doi: 10.1007/s00775-015-1250-x

β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health

2015

Journal Article

Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stress

Ribeiro, Thales P., Fernandes, Christiane, Melo, Karen V., Ferreira, Sarah S., Lessa, Josane A., Franco, Roberto W A., Schenk, Gerhard, Pereira, Marcos D. and Horn, Adolfo (2015). Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stress. Free Radical Biology and Medicine, 80, 67-76. doi: 10.1016/j.freeradbiomed.2014.12.005

Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stress

2014

Journal Article

A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanism

Guilfoyle, Amy P., Deshpande, Chandrika N., Font Sadurni, Josep, Ash, Miriam-Rose, Tourle, Samuel, Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanism. Biophysical Journal, 107 (12), L45-L48. doi: 10.1016/j.bpj.2014.10.064

A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanism

2014

Journal Article

Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release

Guilfoyle, Amy P., Deshpande, Chandrika N., Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release. Bioscience Reports, 34 (6) e00158, 789-796. doi: 10.1042/BSR20140152

Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release

2014

Journal Article

X-ray absorption spectroscopy of dinuclear metallohydrolases

Tierney, David L. and Schenk, Gerhard (2014). X-ray absorption spectroscopy of dinuclear metallohydrolases. Biophysical Journal, 107 (6), 1263-1272. doi: 10.1016/j.bpj.2014.07.066

X-ray absorption spectroscopy of dinuclear metallohydrolases

2014

Journal Article

Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models

Bosch, Simone, Comba, Peter, Gahan, Lawrence R. and Schenk, Gerhard (2014). Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models. Inorganic Chemistry, 53 (17), 9036-9051. doi: 10.1021/ic5009945

Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models

2014

Journal Article

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).

Pedroso, Marcelo M., Ely, Fernanda, Mitic, Natasa, Carpenter, Margaret C., Gahan, Lawrence R., Wilcox, Dean E., Larrabee, James L., Ollis, David L. and Schenk, Gerhard (2014). Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).. Journal of Biological Inorganic Chemistry, 19 (8), 1263-1275. doi: 10.1007/s00775-014-1183-9

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).

2014

Journal Article

Metallo-β-lactamases: a major threat to human health

Phelan, Emer K., Miraula, Manfred, Selleck, Christopher, Ollis, David L., Schenk, Gerhard and Mitic, Natasa (2014). Metallo-β-lactamases: a major threat to human health. American Journal of Molecular Biology, 4 (3), 89-104. doi: 10.4236/ajmb.2014.43011

Metallo-β-lactamases: a major threat to human health

2014

Journal Article

Metallo-beta-lactamases and their biomimetic complexes

Daumann, Lena J., Schenk, Gerhard and Gahan, Lawrence R. (2014). Metallo-beta-lactamases and their biomimetic complexes. European Journal of Inorganic Chemistry, 2014 (18), 2869-2885. doi: 10.1002/ejic.201402203

Metallo-beta-lactamases and their biomimetic complexes

2014

Journal Article

Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups

Fernandes, Christiane, Horn, Adolfo, Vieira-Da-Motta, Olney, Kanashiro, Milton M., Rocha, Michelle R., Moreira, Rafaela O., Morcelli, Samila R., Lopes, Bruna F., Mathias, Luciana da S., Borges, Franz V., Borges, Layla J. H., Freitas, William R., Visentin, Lorenzo C., Almeida, Joao C. de A. and Schenk, Gerhard (2014). Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups. Inorganica Chimica Acta, 416, 35-48. doi: 10.1016/j.ica.2014.02.040

Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups

2014

Journal Article

Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate

Guilfoyle, Amy P., Deshpande, Chandrika N., Vincent, Kimberley, Pedroso, Marcelo M., Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate. FEBS Journal, 281 (9), 2254-2265. doi: 10.1111/febs.12779

Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate

2014

Journal Article

The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginases

McGeary, Ross P., Schenk, Gerhard and Guddat, Luke W. (2014). The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginases. European Journal of Medicinal Chemistry, 76, 132-144. doi: 10.1016/j.ejmech.2014.02.008

The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginases

2014

Journal Article

Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry

Pedroso, Marcelo M., Ely, Fernanda, Lonhienne, Thierry, Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2014). Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. Journal of Biological Inorganic Chemistry, 19 (3), 389-398. doi: 10.1007/s00775-013-1079-0

Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry