2015 Journal Article An approach to more accurate model systems for purple acid phosphatases (PAPs)Bernhardt, Paul V., Bosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Mereacre, Valeriu, Noble, Christopher J., Powell, Annie K., Schenk, Gerhard and Wadepohl, Hubert (2015). An approach to more accurate model systems for purple acid phosphatases (PAPs). Inorganic Chemistry, 54 (15), 7249-7263. doi: 10.1021/acs.inorgchem.5b00628 |
2015 Journal Article A Heterodinuclear Fe<sup>III</sup>Zn<sup>II</sup> Complex as a Mimic for Purple Acid Phosphatase with Site-Specific Zn<sup>II</sup> BindingRoberts, Asha E, Schenk, Gerhard and Gahan, Lawrence R (2015). A Heterodinuclear FeIIIZnII Complex as a Mimic for Purple Acid Phosphatase with Site-Specific ZnII Binding. European Journal of Inorganic Chemistry, 2015 (19), 3076-3086. doi: 10.1002/ejic.201500351 |
2015 Journal Article Altering the substrate specificity of methyl parathion hydrolase with directed evolutionNg, Tee-Kheang, Gahan, Lawrence R., Schenk, Gerhard and Ollis, David L. (2015). Altering the substrate specificity of methyl parathion hydrolase with directed evolution. Archives of Biochemistry and Biophysics, 573, 59-68. doi: 10.1016/j.abb.2015.03.012. |
2015 Journal Article Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ionsQuiñones, Matías, Cofre, Jaime, Benítez, José, García, David, Romero, Nicol, González, Arlette, Carvajal, Nelson, García, María, López, Vasthi, Schenk, Gerhard and Uribe, Elena (2015). Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ions. Journal of Inorganic Biochemistry, 145, 65-69. doi: 10.1016/j.jinorgbio.2015.01.008 |
2015 Journal Article Inteins—A focus on the biotechnological applications of splicing-promoting proteinsMiraula, Manfredi, Enculescu, Charmaine, Schenk, Gerhard and Mitić, Nataša (2015). Inteins—A focus on the biotechnological applications of splicing-promoting proteins. American Journal of Molecular Biology, 05 (02), 42-56. doi: 10.4236/ajmb.2015.52005 |
2015 Journal Article β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human healthMiraula, Manfredi, Whitaker, Jacob J, Schenk, Gerhard and Mitic, Natasa (2015). β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health. Journal of Biological Inorganic Chemistry, 20 (4), 639-651. doi: 10.1007/s00775-015-1250-x |
2015 Journal Article Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stressRibeiro, Thales P., Fernandes, Christiane, Melo, Karen V., Ferreira, Sarah S., Lessa, Josane A., Franco, Roberto W A., Schenk, Gerhard, Pereira, Marcos D. and Horn, Adolfo (2015). Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stress. Free Radical Biology and Medicine, 80, 67-76. doi: 10.1016/j.freeradbiomed.2014.12.005 |
2014 Journal Article A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanismGuilfoyle, Amy P., Deshpande, Chandrika N., Font Sadurni, Josep, Ash, Miriam-Rose, Tourle, Samuel, Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanism. Biophysical Journal, 107 (12), L45-L48. doi: 10.1016/j.bpj.2014.10.064 |
2014 Journal Article Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP releaseGuilfoyle, Amy P., Deshpande, Chandrika N., Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release. Bioscience Reports, 34 (6) e00158, 789-796. doi: 10.1042/BSR20140152 |
2014 Journal Article X-ray absorption spectroscopy of dinuclear metallohydrolasesTierney, David L. and Schenk, Gerhard (2014). X-ray absorption spectroscopy of dinuclear metallohydrolases. Biophysical Journal, 107 (6), 1263-1272. doi: 10.1016/j.bpj.2014.07.066 |
2014 Journal Article Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase modelsBosch, Simone, Comba, Peter, Gahan, Lawrence R. and Schenk, Gerhard (2014). Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models. Inorganic Chemistry, 53 (17), 9036-9051. doi: 10.1021/ic5009945 |
2014 Journal Article Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).Pedroso, Marcelo M., Ely, Fernanda, Mitic, Natasa, Carpenter, Margaret C., Gahan, Lawrence R., Wilcox, Dean E., Larrabee, James L., Ollis, David L. and Schenk, Gerhard (2014). Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).. Journal of Biological Inorganic Chemistry, 19 (8), 1263-1275. doi: 10.1007/s00775-014-1183-9 |
2014 Journal Article Metallo-β-lactamases: a major threat to human healthPhelan, Emer K., Miraula, Manfred, Selleck, Christopher, Ollis, David L., Schenk, Gerhard and Mitic, Natasa (2014). Metallo-β-lactamases: a major threat to human health. American Journal of Molecular Biology, 4 (3), 89-104. doi: 10.4236/ajmb.2014.43011 |
2014 Journal Article Metallo-beta-lactamases and their biomimetic complexesDaumann, Lena J., Schenk, Gerhard and Gahan, Lawrence R. (2014). Metallo-beta-lactamases and their biomimetic complexes. European Journal of Inorganic Chemistry, 2014 (18), 2869-2885. doi: 10.1002/ejic.201402203 |
2014 Journal Article Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groupsFernandes, Christiane, Horn, Adolfo, Vieira-Da-Motta, Olney, Kanashiro, Milton M., Rocha, Michelle R., Moreira, Rafaela O., Morcelli, Samila R., Lopes, Bruna F., Mathias, Luciana da S., Borges, Franz V., Borges, Layla J. H., Freitas, William R., Visentin, Lorenzo C., Almeida, Joao C. de A. and Schenk, Gerhard (2014). Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups. Inorganica Chimica Acta, 416, 35-48. doi: 10.1016/j.ica.2014.02.040 |
2014 Journal Article Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rateGuilfoyle, Amy P., Deshpande, Chandrika N., Vincent, Kimberley, Pedroso, Marcelo M., Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate. FEBS Journal, 281 (9), 2254-2265. doi: 10.1111/febs.12779 |
2014 Journal Article The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginasesMcGeary, Ross P., Schenk, Gerhard and Guddat, Luke W. (2014). The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginases. European Journal of Medicinal Chemistry, 76, 132-144. doi: 10.1016/j.ejmech.2014.02.008 |
2014 Journal Article Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetryPedroso, Marcelo M., Ely, Fernanda, Lonhienne, Thierry, Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2014). Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. Journal of Biological Inorganic Chemistry, 19 (3), 389-398. doi: 10.1007/s00775-013-1079-0 |
2014 Journal Article Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymesHou, Chun-Feng D., Phelan, Emer K., Miraula, Manfredi, Ollis, David L., Schenk, Gerhard and Mitić, Nataša (2014). Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymes. American Journal of Molecular Biology, 4 (1), 11-15. doi: 10.4236/ajmb.2014.41002 |
2014 Conference Publication Characterization of novel metallo-beta-lactamases from the B3 subgroupMiraula, Manfredi, Schenk, Gerhard and Mitić, Nataša (2014). Characterization of novel metallo-beta-lactamases from the B3 subgroup. EuroBIC 12: 12th European Biological Inorganic Chemistry Conference, Zurich, Switzerland, 24-28 August, 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00775-014-1164-z |