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2017 Journal Article Insights into an evolutionary strategy leading to antibiotic resistanceHou, Chun-Feng D., Liu, Jian-wei, Collyer, Charles, Mitić, Natasha, Pedroso, Marcelo Monteiro, Schenk, Gerhard and Ollis, David L. (2017). Insights into an evolutionary strategy leading to antibiotic resistance. Scientific Reports, 7 (1) 40357, 40357.1-40357.13. doi: 10.1038/srep40357 |
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2017 Conference Publication Polymorphisms in Gabra and Rgs Genes Are Associated with Alcoholism and a Secondary Diagnosis of Liver Cirrhosis: Results Are Sex-LinkedEnculescu, C. V., Ho, A. M. C., Rueda, A. V., Fortes, M. R. S., Shamsollahi, G., James, D. P., Schenk, G., Camarini, R., Dodd, P. R. and Stadlin, A. (2017). Polymorphisms in Gabra and Rgs Genes Are Associated with Alcoholism and a Secondary Diagnosis of Liver Cirrhosis: Results Are Sex-Linked. 40th Annual Scientific Meeting of the Research-Society-on-Alcoholism (RSA), Denver CO, United States, 24-28 June 2017. Hoboken, NJ United States: Wiley. |
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2017 Journal Article Mammalian agmatinases constitute unusual members in the family of Mn2+-dependent ureahydrolasesRomero, Nicol, Benitez, José, Garcia, David, Gonzalez, Arlette, Bennun, Leonardo, Garcia-Robles, María A., Lopez, Vasthi, Wilson, Liam A., Schenk, Gerhard, Carvajal, Nelson and Uribe, Elena (2017). Mammalian agmatinases constitute unusual members in the family of Mn2+-dependent ureahydrolases. Journal of Inorganic Biochemistry, 166, 122-125. doi: 10.1016/j.jinorgbio.2016.11.015 |
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2017 Conference Publication Ketol-acid-reductoisomerase, an emerging target for herbicides and novel antimicrobial agentsSchenk, Gerhard and Guddat, Luke W. (2017). Ketol-acid-reductoisomerase, an emerging target for herbicides and novel antimicrobial agents. 18th International Conference on Biological Inorganic Chemistry (ICBIC), Florianopolis Brazil, 31 July - 4 August 2017. New York, NY United States: Springer. |
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2016 Journal Article AIM-1: an antibiotic-degrading metallohydrolase that displays mechanistic flexibilitySelleck, Christopher, Larrabee James A., Harmer, Jeffrey, Guddat, Luke W., Mitić, Natasa, Helweh, Waleed, Ollis, David L., Craig, Whitney R., Tierney, David L., Monteiro Pedroso, Marcelo and Schenk, Gerhard (2016). AIM-1: an antibiotic-degrading metallohydrolase that displays mechanistic flexibility. Chemistry, 22 (49), 17704-17714. doi: 10.1002/chem.201602762 |
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2016 Journal Article Product release is rate-limiting for catalytic processing by the Dengue virus proteaseShannon, A. E., Pedroso, M. M., Chappell, K. J., Watterson, D., Liebscher, S., Kok, W. M., Fairlie, D. P., Schenk, G. and Young, P. R. (2016). Product release is rate-limiting for catalytic processing by the Dengue virus protease. Scientific Reports, 6 (1) 37539, 37539. doi: 10.1038/srep37539 |
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2016 Journal Article New strategies to combat tuberculosisSchenk, Gerhard and Guddat, Luke W. (2016). New strategies to combat tuberculosis. Australasian Biotechnology, 26 (3), 52-53. |
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2016 Journal Article Metallohydrolase biomimetics with catalytic and structural flexibilityMendes, Luisa L., Englert, Daniel, Fernandes, Christiane, Gahan, Lawrence R., Schenk, Gerhard and Horn, Adolfo Jr. (2016). Metallohydrolase biomimetics with catalytic and structural flexibility. Dalton Transactions, 45 (46), 18510-18521. doi: 10.1039/c6dt03200a |
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2016 Journal Article PrefaceGahan, Lawrence, Comba, Peter, Schenk, Gerhard, Daumann, Lena, Hambley, Trevor and Berners-Price, Sue (2016). Preface. Journal of Inorganic Biochemistry, 162, 162-163. doi: 10.1016/j.jinorgbio.2016.09.011 |
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2016 Journal Article Promiscuous metallo-β-lactamases: MIM-1 and MIM-2 may play an essential role in quorum sensing networksMiraula, Manfredi, Schenk, Gerhard and Mitic, Natasa (2016). Promiscuous metallo-β-lactamases: MIM-1 and MIM-2 may play an essential role in quorum sensing networks. Journal of Inorganic Biochemistry, 162, 366-375. doi: 10.1016/j.jinorgbio.2015.12.014 |
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2016 Journal Article Organophosphate-degrading metallohydrolases: structure and function of potent catalysts for applications in bioremediationSchenk, Gerhard, Mateen, Irsa, Ng, Tee-Kheang, Pedroso, Marcelo M., Mitic, Natasa, Jafelicci, Miguel, Marques, Rodrigo F. C., Gahan, Lawrence R. and Ollis, David L. (2016). Organophosphate-degrading metallohydrolases: structure and function of potent catalysts for applications in bioremediation. Coordination Chemistry Reviews, 317, 122-131. doi: 10.1016/j.ccr.2016.03.006 |
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2016 Journal Article Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomeraseTadrowski, Sonya, Pedroso, Marcelo M., Sieber, Volker, Larrabee, James A., Guddat, Luke W. and Schenk, Gerhard (2016). Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomerase. Chemistry, 22 (22), 7427-7436. doi: 10.1002/chem.201600620 |
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2016 Journal Article Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1Arjomandi, Omid Khalili, Hussein, Waleed M., Vella, Peter, Yusof, Yusralina, Sidjabat, Hanna E., Schenk, Gerhard and McGeary, Ross P. (2016). Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1. European Journal of Medicinal Chemistry, 114, 318-327. doi: 10.1016/j.ejmech.2016.03.017 |
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2016 Journal Article Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discoveryYou, Lv, Kandale, Ajit, Wun, Shun Jie, McGeary, Ross P., Williams, Simon J., Kobe, Bostjan, Sieber, Volker, Schembri, Mark A., Schenk, Gerhard and Guddat, Luke W. (2016). Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discovery. Febs Journal, 283 (7), 1184-1196. doi: 10.1111/febs.13672 |
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2016 Journal Article Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolasesBrown, Joshua J., Gahan, Lawrence R., Schöffler, Anne, Krenske, Elizabeth H. and Schenk, Gerhard (2016). Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases. Journal of Inorganic Biochemistry, 162, 356-365. doi: 10.1016/j.jinorgbio.2016.02.008 |
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2016 Journal Article Captopril analogues as metallo-β-lactamase inhibitorsYusof, Yusralina, Tan, Daniel T. C., Arjomandi, Omid Khalili, Schenk, Gerhard and McGeary, Ross P. (2016). Captopril analogues as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry Letters, 26 (6), 1589-1593. doi: 10.1016/j.bmcl.2016.02.007 |
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2016 Journal Article Asymmetric mono- and dinuclear GaIII and ZnII complexes as models for purple acid phosphatasesBosch, Simone, Comba, Peter, Gahan, Lawrence R. and Schenk, Gerhard (2016). Asymmetric mono- and dinuclear GaIII and ZnII complexes as models for purple acid phosphatases. Journal of Inorganic Biochemistry, 162, 343-355. doi: 10.1016/j.jinorgbio.2015.12.028 |
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2016 Journal Article CaII binding regulates and dominates the reactivity of a transition-metal-ion-dependent diesterase from Mycobacterium tuberculosisPedroso, Marcelo M., Larrabee, James A., Ely, Fernanda, Gwee, Shuhui E., Mitic, Natasa, Ollis, David L., Gahan, Lawrence R. and Schenk, Gerhard (2016). CaII binding regulates and dominates the reactivity of a transition-metal-ion-dependent diesterase from Mycobacterium tuberculosis. Chemistry - A European Journal, 22 (3), 999-1009. doi: 10.1002/chem.201504001 |
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2015 Journal Article Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptorsFernandes, Christiane, Horn Jr, Adolfo, Lopes, Bruna F., Bull, Erika S., Azeredo, Nathália F., Kanashiro, Milton M., Borges, Franz V., Bortoluzzi, Adailton J., Szpoganicz, Bruno, Pires, Anderson B., Franco, Roberto W. A., de A. Almeida, João Carlos, Maciel, Leide L. F., Resende, Jackson A. L. C. and Schenk, Gerhard (2015). Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptors. Journal of Inorganic Biochemistry, 153, 68-87. doi: 10.1016/j.jinorgbio.2015.09.014 |
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2015 Journal Article Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatasesBosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Noble, Christopher, Schenk, Gerhard and Wadepohl, Hubert (2015). Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatases. Chemistry - A European Journal, 21 (50), 18269-18279. doi: 10.1002/chem.201503348 |
