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2014 Journal Article Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).Pedroso, Marcelo M., Ely, Fernanda, Mitic, Natasa, Carpenter, Margaret C., Gahan, Lawrence R., Wilcox, Dean E., Larrabee, James L., Ollis, David L. and Schenk, Gerhard (2014). Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).. Journal of Biological Inorganic Chemistry, 19 (8), 1263-1275. doi: 10.1007/s00775-014-1183-9 |
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2014 Journal Article Metallo-β-lactamases: a major threat to human healthPhelan, Emer K., Miraula, Manfred, Selleck, Christopher, Ollis, David L., Schenk, Gerhard and Mitic, Natasa (2014). Metallo-β-lactamases: a major threat to human health. American Journal of Molecular Biology, 4 (3), 89-104. doi: 10.4236/ajmb.2014.43011 |
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2014 Journal Article Metallo-beta-lactamases and their biomimetic complexesDaumann, Lena J., Schenk, Gerhard and Gahan, Lawrence R. (2014). Metallo-beta-lactamases and their biomimetic complexes. European Journal of Inorganic Chemistry, 2014 (18), 2869-2885. doi: 10.1002/ejic.201402203 |
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2014 Journal Article Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groupsFernandes, Christiane, Horn, Adolfo, Vieira-Da-Motta, Olney, Kanashiro, Milton M., Rocha, Michelle R., Moreira, Rafaela O., Morcelli, Samila R., Lopes, Bruna F., Mathias, Luciana da S., Borges, Franz V., Borges, Layla J. H., Freitas, William R., Visentin, Lorenzo C., Almeida, Joao C. de A. and Schenk, Gerhard (2014). Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups. Inorganica Chimica Acta, 416, 35-48. doi: 10.1016/j.ica.2014.02.040 |
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2014 Journal Article Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rateGuilfoyle, Amy P., Deshpande, Chandrika N., Vincent, Kimberley, Pedroso, Marcelo M., Schenk, Gerhard, Maher, Megan J. and Jormakka, Mika (2014). Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate. FEBS Journal, 281 (9), 2254-2265. doi: 10.1111/febs.12779 |
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2014 Journal Article The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginasesMcGeary, Ross P., Schenk, Gerhard and Guddat, Luke W. (2014). The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-beta-lactamases and arginases. European Journal of Medicinal Chemistry, 76, 132-144. doi: 10.1016/j.ejmech.2014.02.008 |
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2014 Journal Article Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetryPedroso, Marcelo M., Ely, Fernanda, Lonhienne, Thierry, Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2014). Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. Journal of Biological Inorganic Chemistry, 19 (3), 389-398. doi: 10.1007/s00775-013-1079-0 |
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2014 Journal Article Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymesHou, Chun-Feng D., Phelan, Emer K., Miraula, Manfredi, Ollis, David L., Schenk, Gerhard and Mitić, Nataša (2014). Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymes. American Journal of Molecular Biology, 4 (1), 11-15. doi: 10.4236/ajmb.2014.41002 |
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2014 Journal Article Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediationDaumann, Lena J., Larrabee, James A., Ollis, David, Schenk, Gerhard and Gahan, Lawrence R. (2014). Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation. Journal of Inorganic Biochemistry, 131, 1-7. doi: 10.1016/j.jinorgbio.2013.10.007 |
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2014 Journal Article Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexesDaumann, Lena J., Schenk, Gerhard, Ollis, David L. and Gahan, Lawrence R. (2014). Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Transactions, 43 (3), 910-928. doi: 10.1039/c3dt52287c |
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2014 Conference Publication Kinetics and Structural Analysis of Rv0805 from Mycobacterium tuberculosisPedroso, M., Ely, F., Gahan, L. R., Schenk, G., Ollis, D. L. and Larrabee, J. A. (2014). Kinetics and Structural Analysis of Rv0805 from Mycobacterium tuberculosis. 16th International Conference on Biological Inorganic Chemistry (ICBIC), Grenoble France, 22-26 July 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00775-014-1095-8 |
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2014 Book Chapter Catalytic mechanisms of metallohydrolases containing two metal ionsMitić, Nataša, Miraula, Manfredi, Selleck, Christopher, Hadler, Kieran S., Uribe, Elena, Pedroso, M. M. and Schenk, G. (2014). Catalytic mechanisms of metallohydrolases containing two metal ions. Metal-containing enzymes. (pp. 49-81) edited by Christo Z. Christov. Waltham, MA, United States: Academic Press. doi: 10.1016/bs.apcsb.2014.07.002 |
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2014 Conference Publication Characterization of novel metallo-beta-lactamases from the B3 subgroupMiraula, Manfredi, Schenk, Gerhard and Mitić, Nataša (2014). Characterization of novel metallo-beta-lactamases from the B3 subgroup. EuroBIC 12: 12th European Biological Inorganic Chemistry Conference, Zurich, Switzerland, 24-28 August, 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00775-014-1164-z |
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2013 Journal Article Highly efficient synthetic iron-dependent nucleases activate both intrinsic and extrinsic apoptotic death pathways in leukemia cancer cellsHorn, Adolfo, Jr., Fernandes, Christiane, Parrilha, Gabrieli L., Kanashiro, Milton M., Borges, Franz V., de Melo, Edesio J. T., Schenk, Gerhard, Terenzi, Hernan and Pich, Claus T. (2013). Highly efficient synthetic iron-dependent nucleases activate both intrinsic and extrinsic apoptotic death pathways in leukemia cancer cells. Journal of Inorganic Biochemistry, 128, 38-47. doi: 10.1016/j.jinorgbio.2013.07.019 |
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2013 Journal Article Identification and preliminary characterization of novel B3-type metallo-beta-lactamasesMiraula, Manfredi, Brunton, Conor S., Schenk, Gerhard and Mitić, Nataša (2013). Identification and preliminary characterization of novel B3-type metallo-beta-lactamases. American Journal of Molecular Biology, 3 (4), 198-203. doi: 10.4236/ajmb.2013.34026 |
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2013 Journal Article Identification and characterization of an unusual metallo-beta-lactamase from Serratia proteamaculansVella, Peter, Miraula, Manfredi, Phelan, Emer, Leung, Eleanor W. W., Ely, Fernanda, Ollis, David L., McGeary, Ross P., Schenk, Gerhard and Mitić, Nataša (2013). Identification and characterization of an unusual metallo-beta-lactamase from Serratia proteamaculans. Journal of Biological Inorganic Chemistry, 18 (7), 855-863. doi: 10.1007/s00775-013-1035-z |
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2013 Journal Article Asymmetric zinc(II) complexes as functional and structural models for phosphoesterasesDaumann, Lena J., Marty, Laurene, Schenk, Gerhard and Gahan, Lawrence R. (2013). Asymmetric zinc(II) complexes as functional and structural models for phosphoesterases. Dalton Transactions, 42 (26), 9574-9584. doi: 10.1039/c3dt50514f |
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2013 Journal Article Dinuclear cobalt(II) omplexes as metallo--lactamase mimicsDaumann, Lena J., Larrabee, James A., Comba, Peter, Schenk, Gerhard and Gahan, Lawrence R. (2013). Dinuclear cobalt(II) omplexes as metallo--lactamase mimics. European Journal of Inorganic Chemistry, 2013 (17), 3082-3089. doi: 10.1002/ejic.201300280 |
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2013 Journal Article Ligand modifications modulate the mechanism of binuclear phosphatase biomimeticsDalle, Kristian E., Daumann, Lena J., Schenk, Gerhard, McGeary, Ross P., Hanton, Lyall R. and Gahan, Lawrence R. (2013). Ligand modifications modulate the mechanism of binuclear phosphatase biomimetics. Polyhedron, 52, 1336-1343. doi: 10.1016/j.poly.2012.06.008 |
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2013 Journal Article Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexesDaumann, Lena J., Comba, Peter, Larrabee, James A., Schenk, Gerhard, Stranger, Robert, Cavigiasso, German and Gahan, Lawrence R. (2013). Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexes. Inorganic Chemistry, 52 (4), 2029-2043. doi: 10.1021/ic302418x |
