2014 Journal Article Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymesHou, Chun-Feng D., Phelan, Emer K., Miraula, Manfredi, Ollis, David L., Schenk, Gerhard and Mitić, Nataša (2014). Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymes. American Journal of Molecular Biology, 4 (1), 11-15. doi: 10.4236/ajmb.2014.41002 |
2014 Conference Publication Kinetics and Structural Analysis of Rv0805 from Mycobacterium tuberculosisPedroso, M., Ely, F., Gahan, L. R., Schenk, G., Ollis, D. L. and Larrabee, J. A. (2014). Kinetics and Structural Analysis of Rv0805 from Mycobacterium tuberculosis. 16th International Conference on Biological Inorganic Chemistry (ICBIC), Grenoble France, 22-26 July 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00775-014-1095-8 |
2014 Book Chapter Catalytic mechanisms of metallohydrolases containing two metal ionsMitić, Nataša, Miraula, Manfredi, Selleck, Christopher, Hadler, Kieran S., Uribe, Elena, Pedroso, M. M. and Schenk, G. (2014). Catalytic mechanisms of metallohydrolases containing two metal ions. Metal-containing enzymes. (pp. 49-81) edited by Christo Z. Christov. Waltham, MA, United States: Academic Press. doi: 10.1016/bs.apcsb.2014.07.002 |
2014 Conference Publication Characterization of novel metallo-beta-lactamases from the B3 subgroupMiraula, Manfredi, Schenk, Gerhard and Mitić, Nataša (2014). Characterization of novel metallo-beta-lactamases from the B3 subgroup. EuroBIC 12: 12th European Biological Inorganic Chemistry Conference, Zurich, Switzerland, 24-28 August, 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00775-014-1164-z |
2014 Journal Article Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediationDaumann, Lena J., Larrabee, James A., Ollis, David, Schenk, Gerhard and Gahan, Lawrence R. (2014). Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation. Journal of Inorganic Biochemistry, 131, 1-7. doi: 10.1016/j.jinorgbio.2013.10.007 |
2014 Journal Article Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexesDaumann, Lena J., Schenk, Gerhard, Ollis, David L. and Gahan, Lawrence R. (2014). Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Transactions, 43 (3), 910-928. doi: 10.1039/c3dt52287c |
2013 Journal Article Highly efficient synthetic iron-dependent nucleases activate both intrinsic and extrinsic apoptotic death pathways in leukemia cancer cellsHorn, Adolfo, Jr., Fernandes, Christiane, Parrilha, Gabrieli L., Kanashiro, Milton M., Borges, Franz V., de Melo, Edesio J. T., Schenk, Gerhard, Terenzi, Hernan and Pich, Claus T. (2013). Highly efficient synthetic iron-dependent nucleases activate both intrinsic and extrinsic apoptotic death pathways in leukemia cancer cells. Journal of Inorganic Biochemistry, 128, 38-47. doi: 10.1016/j.jinorgbio.2013.07.019 |
2013 Journal Article Identification and preliminary characterization of novel B3-type metallo-beta-lactamasesMiraula, Manfredi, Brunton, Conor S., Schenk, Gerhard and Mitić, Nataša (2013). Identification and preliminary characterization of novel B3-type metallo-beta-lactamases. American Journal of Molecular Biology, 3 (4), 198-203. doi: 10.4236/ajmb.2013.34026 |
2013 Journal Article Identification and characterization of an unusual metallo-beta-lactamase from Serratia proteamaculansVella, Peter, Miraula, Manfredi, Phelan, Emer, Leung, Eleanor W. W., Ely, Fernanda, Ollis, David L., McGeary, Ross P., Schenk, Gerhard and Mitić, Nataša (2013). Identification and characterization of an unusual metallo-beta-lactamase from Serratia proteamaculans. Journal of Biological Inorganic Chemistry, 18 (7), 855-863. doi: 10.1007/s00775-013-1035-z |
2013 Journal Article Asymmetric zinc(II) complexes as functional and structural models for phosphoesterasesDaumann, Lena J., Marty, Laurene, Schenk, Gerhard and Gahan, Lawrence R. (2013). Asymmetric zinc(II) complexes as functional and structural models for phosphoesterases. Dalton Transactions, 42 (26), 9574-9584. doi: 10.1039/c3dt50514f |
2013 Journal Article Dinuclear cobalt(II) omplexes as metallo--lactamase mimicsDaumann, Lena J., Larrabee, James A., Comba, Peter, Schenk, Gerhard and Gahan, Lawrence R. (2013). Dinuclear cobalt(II) omplexes as metallo--lactamase mimics. European Journal of Inorganic Chemistry, 2013 (17), 3082-3089. doi: 10.1002/ejic.201300280 |
2013 Journal Article Ligand modifications modulate the mechanism of binuclear phosphatase biomimeticsDalle, Kristian E., Daumann, Lena J., Schenk, Gerhard, McGeary, Ross P., Hanton, Lyall R. and Gahan, Lawrence R. (2013). Ligand modifications modulate the mechanism of binuclear phosphatase biomimetics. Polyhedron, 52, 1336-1343. doi: 10.1016/j.poly.2012.06.008 |
2013 Journal Article Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexesDaumann, Lena J., Comba, Peter, Larrabee, James A., Schenk, Gerhard, Stranger, Robert, Cavigiasso, German and Gahan, Lawrence R. (2013). Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexes. Inorganic Chemistry, 52 (4), 2029-2043. doi: 10.1021/ic302418x |
2013 Journal Article Purple acid phosphatase: a journey into the function and mechanism of a colorful enzymeSchenk, Gerhard, Mitić, Nataša, Hanson, Graeme R. and Comba, Peter (2013). Purple acid phosphatase: a journey into the function and mechanism of a colorful enzyme. Coordination Chemistry Reviews, 257 (2), 473-482. doi: 10.1016/j.ccr.2012.03.020 |
2013 Journal Article Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQDaumann, Lena J., McCarthy, Bianca Y., Hadler, Kieran S., Murray, Tracy P., Gahan, Lawrence R., Larrabee, James A., Ollis, David L. and Schenk, Gerhard (2013). Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1834 (1), 425-432. doi: 10.1016/j.bbapap.2012.02.004 |
2012 Journal Article Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeuticsFeder, Daniel, Hussein, Waleed M., Clayton, Daniel J., Kan, Meng-Wei, Schenk, Gerhard, McGeary, Ross P. and Guddat, Luke W. (2012). Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics. Chemical Biology and Drug Design, 80 (5), 665-674. doi: 10.1111/cbdd.12001 |
2012 Journal Article Spectroscopic characterization of the active (FeFeIII)-Fe-III and (FeFeII)-Fe-III forms of a purple acid phosphatase model systemComba, Peter, Gahan, Lawrence R., Mereacre, Valeriu, Hanson, Graeme R., Powell, Annie K., Schenk, Gerhard and Zajaczkowski-Fischer, Marta (2012). Spectroscopic characterization of the active (FeFeIII)-Fe-III and (FeFeII)-Fe-III forms of a purple acid phosphatase model system. Inorganic Chemistry, 51 (22), 12195-12209. doi: 10.1021/ic301347t |
2012 Journal Article Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosaHussein, Waleed M., Fatahala, Samar S., Mohamed, Zainab M., McGeary, Ross P., Schenk, Gerhard, Ollis, David L. and Mohamed, Mosaad S. (2012). Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa. Chemical Biology and Drug Design, 80 (4), 500-515. doi: 10.1111/j.1747-0285.2012.01440.x |
2012 Journal Article Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycleWong, Sze-Ho, Lonhienne, Thierry G. A., Winzor, Donald J., Schenk, Gerhard and Guddat, Luke W. (2012). Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle. Journal of Molecular Biology, 424 (3-4), 168-179. doi: 10.1016/j.jmb.2012.09.018 |
2012 Journal Article Binuclear metallohydrolases: Complex mechanistic strategies for a simple chemical reactionSchenk, Gerhard, Mitić, Nataša, Gahan, Lawrence R., Ollis, David L., McGeary, Ross P. and Guddat, Luke W. (2012). Binuclear metallohydrolases: Complex mechanistic strategies for a simple chemical reaction. Accounts of Chemical Research, 45 (9), 1593-1603. doi: 10.1021/ar300067g |