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2012

Journal Article

Insights into processing and cyclization events associated with biosynthesis of the cyclic peptide kalata B1

Conlan, Brendon F., Colgrave, Michelle L., Gillon, Amanda D., Guarino, Rosemary, Craik, David J. and Anderson, Marilyn A. (2012). Insights into processing and cyclization events associated with biosynthesis of the cyclic peptide kalata B1. Journal of Biological Chemistry, 287 (33), 28037-28046. doi: 10.1074/jbc.M112.347823

Insights into processing and cyclization events associated with biosynthesis of the cyclic peptide kalata B1

2012

Journal Article

Cyclic peptides from plants and their promise in drug design

Daly, Norelle, David Wilson and Craik, David (2012). Cyclic peptides from plants and their promise in drug design. Australian Biochemist, 43 (2), 7-9.

Cyclic peptides from plants and their promise in drug design

2012

Journal Article

Quantification of small cyclic disulfide-rich peptides

Conibear, Anne, Daly, Norelle L. and Craik, David J. (2012). Quantification of small cyclic disulfide-rich peptides. Biopolymers, 98 (6), 518-524. doi: 10.1002/bip.22121

Quantification of small cyclic disulfide-rich peptides

2012

Journal Article

Discovery and applications of disulfide-rich cyclic peptides

Cemazar, M., Kwon, S., Mahatmanto, T., Ravipati, A. S. and Craik, David J. (2012). Discovery and applications of disulfide-rich cyclic peptides. Current Topics in Medicinal Chemistry, 12 (14), 1534-1545. doi: 10.2174/156802612802652484

Discovery and applications of disulfide-rich cyclic peptides

2012

Journal Article

Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis

Mylne, Joshua S., Chan, Lai Yue, Chanson, Aurelie H., Daly, Norelle L., Schaefer, Hanno, Bailey, Timothy L., Nguyencong, Philip, Cascales, Laura and Craik, David J. (2012). Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis. Plant Cell, 24 (7), 2765-2778. doi: 10.1105/tpc.112.099085

Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis

2012

Journal Article

Thematic minireview series on circular proteins

Craik, David J. and Allewell, Norma M. (2012). Thematic minireview series on circular proteins. Journal of Biological Chemistry, 287 (32), 26999-27000. doi: 10.1074/jbc.R112.390344

Thematic minireview series on circular proteins

2012

Journal Article

Therapeutic potential of conopeptides

Schroeder, Christina I. and Craik, David J. (2012). Therapeutic potential of conopeptides. Future Medicinal Chemistry, 4 (10), 1243-1255. doi: 10.4155/FMC.12.70

Therapeutic potential of conopeptides

2012

Journal Article

Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor

Yu, Rilei, Kaas, Quentin and Craik, David J. (2012). Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor. The Journal of Physical Chemistry B, 116 (21), 6097-6105. doi: 10.1021/jp301352d

Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor

2012

Journal Article

Discovery and applications of naturally occurring cyclic peptides

Thorstholm, L. and Craik, D. J. (2012). Discovery and applications of naturally occurring cyclic peptides. Drug Discovery Today: Technologies, 9 (1), e13-e21. doi: 10.1016/j.ddtec.2011.07.005

Discovery and applications of naturally occurring cyclic peptides

2012

Journal Article

Dermatophytic defensin with antiinfective potential

Zhu, Shunyi, Gao, Bin, Harvey, Peta J. and Craik, David J. (2012). Dermatophytic defensin with antiinfective potential. Proceedings of the National Academy of Sciences of the United States of America, 109 (22), 8495-8500. doi: 10.1073/pnas.1201263109

Dermatophytic defensin with antiinfective potential

2012

Journal Article

Importance of the cell membrane on the mechanism of action of cyclotides

Henriques, Sonia Troeira and Craik, David J. (2012). Importance of the cell membrane on the mechanism of action of cyclotides. ACS Chemical Biology, 7 (4), 626-636. doi: 10.1021/cb200395f

Importance of the cell membrane on the mechanism of action of cyclotides

2012

Journal Article

Cyclization of conotoxins to improve their biopharmaceutical properties

Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012). Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4), 446-455. doi: 10.1016/j.toxicon.2010.12.003

Cyclization of conotoxins to improve their biopharmaceutical properties

2012

Journal Article

Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012). Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 (8) doi: 10.2174/138161212799315858

Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)

2012

Journal Article

Cyclotides as a basis for drug design

Craik, David J., Swedberg, Joakim E., Mylne, Joshua S. and Cemazar, Masa (2012). Cyclotides as a basis for drug design. Expert Opinion On Drug Discovery, 7 (3), 179-194. doi: 10.1517/17460441.2012.661554

Cyclotides as a basis for drug design

2012

Journal Article

Host-defense activities of cyclotides

Craik, David J. (2012). Host-defense activities of cyclotides. Toxins, 4 (2), 139-156. doi: 10.3390/toxins4020139

Host-defense activities of cyclotides

2012

Journal Article

RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs

Franco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams. David J. and Mari, Frank (2012). RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs. Biochemical Pharmacology, 83 (3), 419-426. doi: 10.1016/j.bcp.2011.11.006

RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs

2012

Journal Article

Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane

Pinto, Michelle F. S., Fensterseifer, Isabel C. M., Migliolo, Ludovico, Sousa, Daniel A., de Capdville, Guy, Arboleda, Jorge W., Colgrave, Michelle, Craik, David J., Magalhaes, Beatriz S., Dias, Simoni C. and Franco, Octavio L. (2012). Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane. The Journal of Biological Chemistry, 287 (1), 134-147. doi: 10.1074/jbc.M111.294009

Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane

2012

Conference Publication

Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors

Bao, Jennifer, Cai, Minying, Craik, David and Hruby, Victor (2012). Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors. Experimental Biology Meeting, San Diego Ca, 21-25 April 2012. Bethesda, MD, United States: Federation of American Societies for Experimental Biology (FASEB).

Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors

2012

Conference Publication

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, R. J., Tan, C., Preza, G. C., Nemeth, E., Ganz, T. and Craik, D. J. (2012). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 2-7 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2012

Journal Article

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance