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2010

Journal Article

Isolation, sequencing, and structure - Activity relationships of cyclotides

Ireland, David C., Clark, Richard J., Daly, Norelle L. and Craik, David J. (2010). Isolation, sequencing, and structure - Activity relationships of cyclotides. Journal of Natural Products, 73 (9), 1610-1622. doi: 10.1021/np1000413

Isolation, sequencing, and structure - Activity relationships of cyclotides

2010

Journal Article

Chemical synthesis and structure of the prokineticin Bv8

Morales, Rodrigo A. V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, MacDonald J., King, Glenn F., Alewood, Paul F. and Durek, Thomas (2010). Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13), 1882-1888. doi: 10.1002/cbic.201000330

Chemical synthesis and structure of the prokineticin Bv8

2010

Journal Article

The engineering of an orally active conotoxin for the treatment of neuropathic pain

Clark, Richard J., Jensen, Jonas, Nevin, Simon T., Callaghan, Brid P., Adams, David J. and Craik, David J. (2010). The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angewandte Chemie (International Edition), 49 (37), 6545-6548. doi: 10.1002/anie.201000620

The engineering of an orally active conotoxin for the treatment of neuropathic pain

2010

Journal Article

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

Dunse, K. M., Kaas, Q., Guarino, R. F., Barton, P. A., Craik, D. J. and Anderson, M. A. (2010). Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America., 107 (34), 15016-15021. doi: 10.1073/pnas.1009327107

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

2010

Journal Article

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 31 (8), 1434-1440. doi: 10.1016/j.peptides.2010.05.004

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

2010

Journal Article

Stability studies of oxazolidine-based compounds using 1H NMR spectroscopy

Moloney, Gerard P., Iskander, Magdy N. and Craik, David J. (2010). Stability studies of oxazolidine-based compounds using 1H NMR spectroscopy. Journal of Pharmaceutical Sciences, 99 (8), 3362-3371. doi: 10.1002/jps.22108

Stability studies of oxazolidine-based compounds using 1H NMR spectroscopy

2010

Journal Article

Conopeptide characterization and classifications: An analysis using ConoServer

Kaas, Quentin, Westermann, Jan-Christoph and Craik, David J. (2010). Conopeptide characterization and classifications: An analysis using ConoServer. Toxicon, 55 (8), 1491-1509. doi: 10.1016/j.toxicon.2010.03.002

Conopeptide characterization and classifications: An analysis using ConoServer

2010

Conference Publication

Structure and activity of the leaf-specific cyclotide vhl-2

Daly, Norelle L., Chen, Bin, Nguyencong, Philip and Craik, David J. (2010). Structure and activity of the leaf-specific cyclotide vhl-2. doi: 10.1071/CH10007

Structure and activity of the leaf-specific cyclotide vhl-2

2010

Journal Article

Cyclotide interactions with the nematode external surface

Colgrave, Michelle L., Huang, Yen-Hua, Craik, David J. and Kotze, Andrew C. (2010). Cyclotide interactions with the nematode external surface. Antimicrobial Agents and Chemotherapy, 54 (5), 2160-2166. doi: 10.1128/AAC.01306-09

Cyclotide interactions with the nematode external surface

2010

Journal Article

Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha 3 beta 2 nicotinic receptor

Luo, Sulan, Akondi, Kalyana Bharati, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Christensen, Sean, Dowell, Cheryl, Daly, Norelle L., Craik, David J., Wang, Ching-I. Anderson, Lewis, Richard J., Alewood, Paul F. and McIntosh, J. Michael (2010). Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha 3 beta 2 nicotinic receptor. Journal of Biological Chemistry, 285 (16), 12355-12366. doi: 10.1074/jbc.M109.079012

Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha 3 beta 2 nicotinic receptor

2010

Journal Article

Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity

Huang, Yen-Hua (黃彥華), Colgrave, Michelle L., Clark, Richard J., Kotze, Andrew C. and Craik, David J. (2010). Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity. Journal of Biological Chemistry, 285 (14), 10797-10805. doi: 10.1074/jbc.M109.089854

Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity

2010

Journal Article

Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogues

Armishaw, Christopher J., Dutton, Julie L., Craik, David J. and Alewood, Paul F. (2010). Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogues. Biopolymers: Peptide Science, 94 (3), 307-313. doi: 10.1002/bip.21360

Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogues

2010

Journal Article

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

Muttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

2010

Journal Article

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

Qin, Qiaoping, McCallum, Emily J., Kaas, Quentin, Suda, Jan, Saska, Ivana, Craik, David J. and Mylne, Joshua S. (2010). Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis. BMC Genomics, 11 (111) 111, 1-11. doi: 10.1186/1471-2164-11-111

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

2010

Conference Publication

Discovery and distribution of circular peptides in flowering plants

Gruber, C. W., Craik, D. and Kopp, B. (2010). Discovery and distribution of circular peptides in flowering plants. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1301

Discovery and distribution of circular peptides in flowering plants

2010

Journal Article

Cyclotides are a component of the innate defense of Oldenlandia affinis

Mylne, Joshua S, Wang, Conan K, van der Weerden, Nicole L and Craik, David J (2010). Cyclotides are a component of the innate defense of Oldenlandia affinis. Biopolymers, 94 (5), 635-646. doi: 10.1002/bip.21419

Cyclotides are a component of the innate defense of Oldenlandia affinis

2010

Conference Publication

PepTalk - CHI's ninth annual meeting - Engineering protein & Peptide therapeutics: Peptides - conference report

Craik, David J. (2010). PepTalk - CHI's ninth annual meeting - Engineering protein & Peptide therapeutics: Peptides - conference report. PepTalk, Nottingham, United Kingdom, 14-15 January 2010. U.K.: Current Drugs Ltd.

PepTalk - CHI's ninth annual meeting - Engineering protein & Peptide therapeutics: Peptides - conference report

2010

Book Chapter

NMR-based screening and drug discovery

Craik, David J., Smith, Philippa A. and Clark, Richard James (2010). NMR-based screening and drug discovery. Burger's medicinal chemistry, drug discovery, and development. (pp. 359-437) edited by Donald J. Abraham, David P. Rotella and Alfred Burger. Hoboken, N.J.: Wiley. doi: 10.1002/0471266949

NMR-based screening and drug discovery

2010

Conference Publication

Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice

Burman, Robert, Svedlund, Erika, Felth, Jenny, Hassan, Saadia, Hermann, Anders, Clark, Richard James, Craik, David J., Bohlin, Lars, Claeson, Per, Goransson, Ulf and Gullbo, Joachim (2010). Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October, 2009. Hoboken, NJ, U.S.A: Wiley Interscience. doi: 10.1002/bip.21408

Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice

2010

Journal Article

Cyclotide proteins and precursors from the genus Gloeospermum: Filling a blank spot in the cyclotide map of Violaceae

Burman, Robert, Gruber, Christian W., Rizzardi, Kristina, Herrmann, Anders, Craik, David J., Gupta, Mahabir P. and Goransson, Ulf (2010). Cyclotide proteins and precursors from the genus Gloeospermum: Filling a blank spot in the cyclotide map of Violaceae. Phytochemistry, 71 (1), 13-20. doi: 10.1016/j.phytochem.2009.09.023

Cyclotide proteins and precursors from the genus Gloeospermum: Filling a blank spot in the cyclotide map of Violaceae