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2011

Journal Article

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2011

Journal Article

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

2011

Journal Article

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

Akcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

2011

Conference Publication

Discovery and applications of naturally occurring cyclic peptides

Craik, D., Poth, A., Colgrave, M., Akcan, M., Oku, B., Chan, A. and Daly, N. (2011). Discovery and applications of naturally occurring cyclic peptides. 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Antalya, Turkey, 4-9 September 2011. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0031-1282086

Discovery and applications of naturally occurring cyclic peptides

2011

Conference Publication

Conotoxins - blueprints for GPCR drug discovery?

Muttenthaler, M., Gruber, C. W., Andersson, A., Vetter, I., Nevin, S. T., Grishin, A. A., Dutertre, S., Daly, N. L., Craik, D. J., Adams, D. J., Lewis, R. J. and Alewood, P. F. (2011). Conotoxins - blueprints for GPCR drug discovery?. 22nd American Peptide Symposium, San Diego, CA, United States, 25-30 June 2011. Hoboken, NJ, United States: John Wiley & Sons.

Conotoxins - blueprints for GPCR drug discovery?

2011

Journal Article

The folding of disulfide-rich proteins

Craik, David J. (2011). The folding of disulfide-rich proteins. Antioxidants and Redox Signaling, 14 (1), 61-64. doi: 10.1089/ars.2010.3656

The folding of disulfide-rich proteins

2011

Journal Article

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization

Lovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization

2011

Journal Article

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

2011

Conference Publication

Naturally Occurring Cyclic Peptides as Templates in Drug Design

Craik, David J., Daly, Norelle L., Chan, Angeline, Mylne, Joshua S., Poth, Aaron and Colgrave, Michelle (2011). Naturally Occurring Cyclic Peptides as Templates in Drug Design. 22nd American Peptide Symposium, San Diego Ca, Jun 25-30, 2011. Malden MA, United States: Wiley-Blackwell Publishing.

Naturally Occurring Cyclic Peptides as Templates in Drug Design

2011

Journal Article

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

Aboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

2011

Journal Article

Conopeptides as novel options for pain management

Daly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066

Conopeptides as novel options for pain management

2011

Conference Publication

Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor

Adams, D. J., Grishin, A. A., Hung, A., Clark, R. J., Akondi, K., Alewood, P. F. and Craik, D. J. (2011). Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor. nAChR2011: Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science, Washington, DC, U.S.A., 9-11 November 2011. Philadelphia, PA, U.S.A.: Elsevier. doi: 10.1016/j.bcp.2011.07.017

Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor

2011

Book Chapter

Conotoxin-based leads in drug design

Akcan, Muharrem and Craik, David J. (2011). Conotoxin-based leads in drug design. Peptide drug discovery and development: Translational research in academia and industry. (pp. 119-137) edited by Miguel Castanho and Nuno C. Santos. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527636730.ch5

Conotoxin-based leads in drug design

2011

Book Chapter

Cystine knot folding in cyclotides

Daly, Norelle L., Gruber, Christian W., Goransson, Ulf and Craik, David J. (2011). Cystine knot folding in cyclotides. Folding of disulfide proteins. (pp. 43-61) edited by Chang, RJY and Ventura, S. New York , NY, U.S.A.: Springer. doi: 10.1007/978-1-4419-7273-6

Cystine knot folding in cyclotides

2011

Conference Publication

Sunflower trypsin inhibitor-1: chemical v. biological synthesis

Elliott, Alysha G., Craik, David J. and Mylne, Joshua S. (2011). Sunflower trypsin inhibitor-1: chemical v. biological synthesis. 22nd American Peptide Symposium, San Diego, United States, 25-30 June 2011. San Diego, United States: Prompt Scientific Publishing.

Sunflower trypsin inhibitor-1: chemical v. biological synthesis

2010

Journal Article

Discovery and applications of the plant cyclotides

Craik, David J. (2010). Discovery and applications of the plant cyclotides. Toxicon, 56 (7), 1092-1102. doi: 10.1016/j.toxicon.2010.02.021

Discovery and applications of the plant cyclotides

2010

Journal Article

Naturally occurring circular proteins: Distribution, biosynthesis and evolution

Cascales, Laura and Craik, David J. (2010). Naturally occurring circular proteins: Distribution, biosynthesis and evolution. Organic and Biomolecular Chemistry, 8 (22), 5035-5047. doi: 10.1039/c0ob00139b

Naturally occurring circular proteins: Distribution, biosynthesis and evolution

2010

Journal Article

Peptide rope tricks

Rosengren, K. Johan and Craik, David J. (2010). Peptide rope tricks. Chimica Oggi, 28 (6), 28-32.

Peptide rope tricks

2010

Journal Article

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of Bioactive Cyclotides from Viola labrilorica. Helvetica Chimica Acta, 93 (11), 2287-2295. doi: 10.1002/hlca.201000115

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

2010

Journal Article

Structural and functional analysis of human liver-expressed antimicrobial peptide 2

Henriques, Sonia Troeira, Tan, Chia Chia, Craik, David J. and Clark, Richard J. (2010). Structural and functional analysis of human liver-expressed antimicrobial peptide 2. ChemBioChem, 11 (15), 2148-2157. doi: 10.1002/cbic.201000400

Structural and functional analysis of human liver-expressed antimicrobial peptide 2