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2011 Journal Article Bioactive cystine knot proteinsDaly, Norelle L. and Craik, David J. (2011). Bioactive cystine knot proteins. Current Opinion in Chemical Biology, 15 (3), 362-368. doi: 10.1016/j.cbpa.2011.02.008 |
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2011 Journal Article Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30 |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
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2011 Journal Article Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j |
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2011 Journal Article NMR and protein structure in drug design: Application to cyclotides and conotoxinsDaly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9 |
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2011 Journal Article Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculationsYu, Rilei, Craik, David J. and Kaas, Quentin (2011). Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 (3) e1002011, e1002011-1-e1002011-16. doi: 10.1371/journal.pcbi.1002011 |
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2011 Journal Article Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channelsDaly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170 |
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2011 Journal Article Understanding the structure/activity relationships of the iron regulatory peptide hepcidinClark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009 |
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2011 Journal Article Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapyAkcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r |
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2011 Conference Publication Naturally Occurring Cyclic Peptides as Templates in Drug DesignCraik, David J., Daly, Norelle L., Chan, Angeline, Mylne, Joshua S., Poth, Aaron and Colgrave, Michelle (2011). Naturally Occurring Cyclic Peptides as Templates in Drug Design. 22nd American Peptide Symposium, San Diego Ca, Jun 25-30, 2011. Malden MA, United States: Wiley-Blackwell Publishing. |
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2011 Journal Article Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of CyclotidesAboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112 |
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2011 Journal Article Conopeptides as novel options for pain managementDaly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066 |
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2011 Conference Publication Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptorAdams, D. J., Grishin, A. A., Hung, A., Clark, R. J., Akondi, K., Alewood, P. F. and Craik, D. J. (2011). Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor. nAChR2011: Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science, Washington, DC, U.S.A., 9-11 November 2011. Philadelphia, PA, U.S.A.: Elsevier. doi: 10.1016/j.bcp.2011.07.017 |
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2011 Conference Publication Sunflower trypsin inhibitor-1: chemical v. biological synthesisElliott, Alysha G., Craik, David J. and Mylne, Joshua S. (2011). Sunflower trypsin inhibitor-1: chemical v. biological synthesis. 22nd American Peptide Symposium, San Diego, United States, 25-30 June 2011. San Diego, United States: Prompt Scientific Publishing. |
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2011 Book Chapter Conotoxin-based leads in drug designAkcan, Muharrem and Craik, David J. (2011). Conotoxin-based leads in drug design. Peptide drug discovery and development: Translational research in academia and industry. (pp. 119-137) edited by Miguel Castanho and Nuno C. Santos. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527636730.ch5 |
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2011 Book Chapter Cystine knot folding in cyclotidesDaly, Norelle L., Gruber, Christian W., Goransson, Ulf and Craik, David J. (2011). Cystine knot folding in cyclotides. Folding of disulfide proteins. (pp. 43-61) edited by Chang, RJY and Ventura, S. New York , NY, U.S.A.: Springer. doi: 10.1007/978-1-4419-7273-6 |
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2011 Conference Publication Discovery and applications of naturally occurring cyclic peptidesCraik, D., Poth, A., Colgrave, M., Akcan, M., Oku, B., Chan, A. and Daly, N. (2011). Discovery and applications of naturally occurring cyclic peptides. 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Antalya, Turkey, 4-9 September 2011. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0031-1282086 |
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2011 Conference Publication Conotoxins - blueprints for GPCR drug discovery?Muttenthaler, M., Gruber, C. W., Andersson, A., Vetter, I., Nevin, S. T., Grishin, A. A., Dutertre, S., Daly, N. L., Craik, D. J., Adams, D. J., Lewis, R. J. and Alewood, P. F. (2011). Conotoxins - blueprints for GPCR drug discovery?. 22nd American Peptide Symposium, San Diego, CA, United States, 25-30 June 2011. Hoboken, NJ, United States: John Wiley & Sons. |
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2011 Journal Article Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclizationLovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068 |
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2011 Journal Article Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptidesCascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424 |
