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2011 Journal Article Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffoldsChan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141 |
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2011 Journal Article Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptorHalai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r |
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2011 Journal Article α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structureDekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2011). α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40), 15866-15869. doi: 10.1021/ja206408q |
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2011 Journal Article Isolation and characterization of cytotoxic cyclotides from Viola philippicaHe, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2011). Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8), 1719-1723. doi: 10.1016/j.peptides.2011.06.016 |
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2011 Journal Article Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted foldingDantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642 |
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2011 Journal Article Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activitiesHenriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393 |
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2011 Journal Article Discovery of an unusual biosynthetic origin for circular proteins in legumesPoth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L. and Craik, David J. (2011). Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United State of America, 108 (25), 10127-10132. doi: 10.1073/pnas.1103660108 |
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2011 Journal Article Bioactive cystine knot proteinsDaly, Norelle L. and Craik, David J. (2011). Bioactive cystine knot proteins. Current Opinion in Chemical Biology, 15 (3), 362-368. doi: 10.1016/j.cbpa.2011.02.008 |
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2011 Journal Article Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30 |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
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2011 Journal Article Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j |
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2011 Journal Article NMR and protein structure in drug design: Application to cyclotides and conotoxinsDaly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9 |
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2011 Journal Article Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculationsYu, Rilei, Craik, David J. and Kaas, Quentin (2011). Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 (3) e1002011, e1002011-1-e1002011-16. doi: 10.1371/journal.pcbi.1002011 |
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2011 Journal Article Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channelsDaly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170 |
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2011 Journal Article Understanding the structure/activity relationships of the iron regulatory peptide hepcidinClark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009 |
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2011 Journal Article Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapyAkcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r |
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2011 Conference Publication Naturally Occurring Cyclic Peptides as Templates in Drug DesignCraik, David J., Daly, Norelle L., Chan, Angeline, Mylne, Joshua S., Poth, Aaron and Colgrave, Michelle (2011). Naturally Occurring Cyclic Peptides as Templates in Drug Design. 22nd American Peptide Symposium, San Diego Ca, Jun 25-30, 2011. Malden MA, United States: Wiley-Blackwell Publishing. |
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2011 Journal Article Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of CyclotidesAboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112 |
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2011 Journal Article Conopeptides as novel options for pain managementDaly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066 |
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2011 Conference Publication Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptorAdams, D. J., Grishin, A. A., Hung, A., Clark, R. J., Akondi, K., Alewood, P. F. and Craik, D. J. (2011). Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor. nAChR2011: Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science, Washington, DC, U.S.A., 9-11 November 2011. Philadelphia, PA, U.S.A.: Elsevier. doi: 10.1016/j.bcp.2011.07.017 |
