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2012

Journal Article

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

Kaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012). ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 (D1), D325-D330. doi: 10.1093/nar/gkr886

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

2012

Book Chapter

Cyclotide isolation and characterization

Craik, David J., Henriques, Sonia Troeira, Mylne, Joshua S. and Wang, Conan K. (2012). Cyclotide isolation and characterization. Natural product biosynthesis by microorganisms and plants, part B. (pp. 37-62) edited by David A. Hopwood. Burlington, USA: Elsevier. doi: 10.1016/B978-0-12-394291-3.00024-1

Cyclotide isolation and characterization

2012

Conference Publication

Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors

Bao, Jennifer, Cai, Minying, Craik, David and Hruby, Victor (2012). Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors. Experimental Biology Meeting, San Diego Ca, 21-25 April 2012. Bethesda, MD, United States: Federation of American Societies for Experimental Biology (FASEB).

Biological evaluation of cyclized cystine knot peptides targeting human melanocortin receptors

2012

Conference Publication

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, R. J., Tan, C., Preza, G. C., Nemeth, E., Ganz, T. and Craik, D. J. (2012). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 2-7 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2012

Journal Article

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

2012

Conference Publication

Discovery and applications of cyclotides

Craik, D. J. (2012). Discovery and applications of cyclotides. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2446

Discovery and applications of cyclotides

2012

Conference Publication

Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds

Chan, L. A., Gunasekera, S., Henriques, S. T., Worth, N. F., Le, S., Clark, R. J., Campbell, J. H., Craik, D. J. and Daly, N. L. (2012). Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds

2012

Conference Publication

The Importance of the cell membrane on the mechanism of action of cyclotides

Henriques, S. T., Huang, Y. -H., Castanho, M. A. R. B., Daly, N. L. and Craik, D. J. (2012). The Importance of the cell membrane on the mechanism of action of cyclotides. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2449

The Importance of the cell membrane on the mechanism of action of cyclotides

2012

Journal Article

Engineering cyclic peptide toxins

Clark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3

Engineering cyclic peptide toxins

2011

Journal Article

Engineering of conotoxins for the treatment of pain

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401

Engineering of conotoxins for the treatment of pain

2011

Journal Article

A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor

Sando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel and Craik, David J. (2011). A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16), 2456-2462. doi: 10.1002/cbic.201100450

A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor

2011

Journal Article

Cyclotides: A patent review

Smith, Amanda B., Daly, Norelle L. and Craik, David J. (2011). Cyclotides: A patent review. Expert Opinion On Therapeutic Patents, 21 (11), 1657-1672. doi: 10.1517/13543776.2011.620606

Cyclotides: A patent review

2011

Journal Article

Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals

Conibear, Anne C. and Craik, David J. (2011). Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals. Israel Journal of Chemistry, 51 (8-9), 908-916. doi: 10.1002/ijch.201100067

Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals

2011

Journal Article

Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds

Chan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141

Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds

2011

Journal Article

Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor

Halai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r

Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor

2011

Journal Article

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure

Dekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2011). α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40), 15866-15869. doi: 10.1021/ja206408q

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure

2011

Journal Article

Isolation and characterization of cytotoxic cyclotides from Viola philippica

He, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2011). Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8), 1719-1723. doi: 10.1016/j.peptides.2011.06.016

Isolation and characterization of cytotoxic cyclotides from Viola philippica

2011

Journal Article

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

Dantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

2011

Journal Article

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

2011

Journal Article

Discovery of an unusual biosynthetic origin for circular proteins in legumes

Poth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L. and Craik, David J. (2011). Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United State of America, 108 (25), 10127-10132. doi: 10.1073/pnas.1103660108

Discovery of an unusual biosynthetic origin for circular proteins in legumes