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2008

Journal Article

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

Simonsen, S. M., Sando, L., Rosengren, K. J., Wang, C. K., Colgrave, M. L., Daly, N. L. and Craik, D. J. (2008). Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. Journal of Biological Chemistry, 283 (15), 9805-9813. doi: 10.1074/jbc.M709303200

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

2008

Journal Article

Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations

Combelles, C., Gracy, J., Heitz, A., Craik, D. J. and Chiche, L. (2008). Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations. Proteins, 73 (1), 87-103. doi: 10.1002/prot.22054

Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations

2008

Journal Article

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

Dutertre, Sébastien, Croker, Daniel, Daly, Norelle L., Andersson, Åsa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles and Lewis, Richard J. (2008). Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide. Journal of Biological Chemistry, 283 (11), 7100-7108. doi: 10.1074/jbc.M706477200

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

2008

Journal Article

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA

Clark, Richard J., Daly, Norelle L., Halai, Reena, Nevin, Simon T., Adams, David J. and Craik, David J. (2008). The three-dimensional structure of the analgesic alpha-conotoxin, RgIA. FEBS Letters, 582 (5), 597-602. doi: 10.1016/j.febslet.2008.01.027

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA

2008

Journal Article

ConoServer, a database for conopeptide sequences and structures

Kaas, Quentin, Westermann, Jan, Halai, Reena, Wang, Conan and Craik, David J. (2008). ConoServer, a database for conopeptide sequences and structures. Bioinformatics, 24 (3), 445-446. doi: 10.1093/bioinformatics/btm596

ConoServer, a database for conopeptide sequences and structures

2008

Journal Article

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity

Herrman, Anders, Burman, Robert, Mylne, Joshua S., Karlsson, Gustav, Gullbo, Joachim, Craik, David J., Clark, Richard J. and Goransson, Ulf (2008). The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity. Phytochemistry, 69 (4), 939-952. doi: 10.1016/j.phytochem.2007.10.023

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity

2008

Journal Article

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Barbeta, Barbara L., Marshall, Alan T., Gillon, Amanda D., Craik, David J. and Anderson, Marilyn A. (2008). Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae. Proceedings of the National Acadamy of Sciences of the United State of America, 105 (4), 1221-1225. doi: 10.1073/pnas.0710338104

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

2008

Journal Article

Kappa-/beta-carrageenans from Australian red algae of the Acrotylaceae (Gigartinales, Rhodophyta)

Chiovitti, A, Kraft, G, Bacic, A, Craik, David J. and Liao, M-L (2008). Kappa-/beta-carrageenans from Australian red algae of the Acrotylaceae (Gigartinales, Rhodophyta). Phycologia, 47 (1), 35-40. doi: 10.2216/07-10.1

Kappa-/beta-carrageenans from Australian red algae of the Acrotylaceae (Gigartinales, Rhodophyta)

2008

Conference Publication

Selenocysteine in peptide drug design

Adams, D. J., Alewood, P. F., Choy, P. T., Craik, D. J., Daly, N. L., Grishin, A. A., Hu, S-H., Martin, J. L., Muttenthaler, M., Nevin, S. T., Ngo, S. T. and Noakes, P. G. (2008). Selenocysteine in peptide drug design. Royal Australian Chemical Institute (RACI) Annual Scientific Meeting: Drug Discovery and Development, Couran Cove Island Resort, Queensland, Australia, 13 - 17 July 2008.

Selenocysteine in peptide drug design

2008

Journal Article

Cyclotides and conotoxins ultra-stable disulfide-rich peptides

Craik, David J., Clark, Richard J. and Daly, Norelle L. (2008). Cyclotides and conotoxins ultra-stable disulfide-rich peptides. Chimica Oggi -Chemistry Today, 26 (4), 20-22.

Cyclotides and conotoxins ultra-stable disulfide-rich peptides

2008

Journal Article

Biosynthesis of circular proteins in plants

Gillon, Amanda D, Saska, Ivana, Jennings, Cameron V., Guarino, Rosemary F., Craik, David J. and Anderson, Marilyn A. (2008). Biosynthesis of circular proteins in plants. The Plant Journal, 53 (3), 505-515. doi: 10.1111/j.1365-313X.2007.03357.x

Biosynthesis of circular proteins in plants

2008

Conference Publication

The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design

Craik, David, Saska, Ivana, Gruber, Christian, Gillon, Amanda and Anderson, Marilyn (2008). The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1089

The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design

2008

Journal Article

Conotoxin modulation of voltage-gated sodium channels

Ekberg, J, Craik, DJ and Adams, DJ (2008). Conotoxin modulation of voltage-gated sodium channels. The International Journal of Biochemistry & Cell Biology, 40 (11), 2363-2368. doi: 10.1016/j.biocel.2007.08.017

Conotoxin modulation of voltage-gated sodium channels

2008

Book Chapter

NMR in peptide drug development

Jan Westermann and Craik, David J. (2008). NMR in peptide drug development. Peptide-Based Drug Design (Methods in Molecular Biology). (pp. 87-113) edited by Laszlo Otvos. New York: Humana Press. doi: 10.1007/978-1-59745-419-3

NMR in peptide drug development

2008

Conference Publication

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, 3-8 August 2008. Germany: Georg Thieme Verlag.

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

2008

Conference Publication

Selenocysteine in peptide folding and drug design

Muttenthaler, M., Nevin, S. T., Grishin, A. A., Ngo, S. T., Choy, P. T., Daly, N. L., Hu, S-H., Martin, J. L., Noakes, P. G., Craik, D. J., Adams, D. J. and Alewood, P. F. (2008). Selenocysteine in peptide folding and drug design. XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Vienna, Austria, 31 August - 4 September 2008.

Selenocysteine in peptide folding and drug design

2008

Book Chapter

Structure-based Drug Design and NMR-based screening

Craik, D. J. and Clark, R. J. (2008). Structure-based Drug Design and NMR-based screening. Pharmacology from drug development to gene therapy. (pp. 225-313) edited by R. A. Meyers. Weinheim: Wiley-VCH Verlag GMBH & Co.

Structure-based Drug Design and NMR-based screening

2008

Journal Article

Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

Aboye, T, Clark, Richard J., Craik, David J. and Goransson, U (2008). Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. ChemBioChem, 9 (1), 103-113. doi: 10.1002/cbic.200700357

Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

2008

Journal Article

Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis

Wang, Conan K. L., Colgrave, Michelle L., Gustafson, Kirk R., Ireland, David C., Goransson, Ulf and Craik, David J. (2008). Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis. Journal of Natural Products, 71 (1), 47-52. doi: 10.1021/np070393g

Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis

2008

Conference Publication

Understanding the structure/activity relationships of hepcidin

Clark, Richard, Tan, Chia Chia, Nemeth, Elizabeta, Ganz, Thomas and Craik, David (2008). Understanding the structure/activity relationships of hepcidin. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090

Understanding the structure/activity relationships of hepcidin