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2006

Journal Article

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

Rosengren, K. J., Zhang, S., Lin, F., Daly, N. L., Scott, D. J., Hughes, R. A., Bathgate, R. A. D., Craik, D. J. and Wade, J. D. (2006). Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3. Journal of Biological Chemistry, 281 (38), 28287-28295. doi: 10.1074/jbc.M603829200

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

2006

Journal Article

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

Armishaw, Christopher J., Daly, Norelle L., Nevin, Simon T., Adams, David J., Craik, David J. and Alewood, Paul F. (2006). Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists. Journal of Biological Chemistry, 281 (20), 14136-14143. doi: 10.1074/jbc.M512419200

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

2006

Journal Article

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

Ireland, David C., Colgrave, Michelle L., Nguyencong, Philip, Daly, Norelle L. and Craik, David J. (2006). Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins. Journal of Molecular Biology, 357 (5), 1522-1535. doi: 10.1016/j.jmb.2006.01.051

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

2006

Journal Article

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

Rosengren, K. J., Lin, F., Bathgate, R. A. D., Tregear, G. W., Daly, N. L., Wade, J. D. and Craik, D. J. (2006). Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3. Journal of Biological Chemistry, 281 (9), 5845-5851. doi: 10.1074/jbc.M511210200

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

2006

Conference Publication

Bioengineered cyclic peptides for treatment of multiple sclerosis

Cemazar, M., Bernard, C. C. and Craik, D. J. (2006). Bioengineered cyclic peptides for treatment of multiple sclerosis. 29th European Peptide Symposium, Gdansk, Poland, 3 - 8 September, 2006. Chichester, England: John Wiley & Sons. doi: 10.1002/psc.797

Bioengineered cyclic peptides for treatment of multiple sclerosis

2006

Journal Article

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

Mulvenna, J. P., Mylne, J. S., Bharathi, R., Burton, R. A., Shirley, N. J., Fincher, G. B., Anderson, M. A. and Craik, D. J. (2006). Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?. Plant Cell, 18 (9), 2134-2144. doi: 10.1105/tpc.106.042812

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

2006

Journal Article

The cyclotides and related macrocyclic peptides as scaffolds in drug design

Craik, D. J., Cemazar, M. and Daly, N. L. (2006). The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 9 (2), 251-260.

The cyclotides and related macrocyclic peptides as scaffolds in drug design

2006

Book Chapter

Overview of NMR in the Pharmaceutical Sciences

Schirra, H. J. and Craik, D. J. (2006). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance Part 2: Applications in Medical and Pharmaceutical Sciences. (pp. 1177-1184) edited by Graham A. Webb. Netherlands: Springer.

Overview of NMR in the Pharmaceutical Sciences

2006

Conference Publication

Bioengineering cyclic peptides for treatment of multiple sclerosis

Cemazar, M, Bernard, C and Craik, DJ (2006). Bioengineering cyclic peptides for treatment of multiple sclerosis. 8th International Conference of Neuroimmunology, Nagoya Japan, Oct 15-19, 2006. AMSTERDAM: JOHN WILEY & SONS INC.

Bioengineering cyclic peptides for treatment of multiple sclerosis

2006

Conference Publication

Animal, Plant and Microbial Toxins - 15th World Congress - 23-28 July 2006, Glasgow, UK

Craik, D (2006). Animal, Plant and Microbial Toxins - 15th World Congress - 23-28 July 2006, Glasgow, UK. London: Current Drugs Ltd.

Animal, Plant and Microbial Toxins - 15th World Congress - 23-28 July 2006, Glasgow, UK

2006

Journal Article

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

Daly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

2006

Journal Article

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

Chen, B., Colgrave, M. L., Wang, C. N. and Craik, D. J. (2006). Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Journal of Natural Products, 69 (1), 23-28. doi: 10.1021/np050317i

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

2006

Journal Article

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold

Daly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold

2006

Journal Article

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

Ireland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochemical Journal, 400 (Part 1), 1-12. doi: 10.1042/BJ20060627

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

2006

Conference Publication

Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates

Craik, David J., Rosengren, K. Johan, Sando, Lillian and Simonsen, Shane S. (2006). Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_101

Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates

2006

Journal Article

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

Cemazar, M. and Craik, D. J. (2006). Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif. International Journal of Peptide Research And Therapeutics, 12 (3), 253-260. doi: 10.1007/s10989-006-9019-2

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

2006

Conference Publication

Peptides and therapeutic proteins - SRI Conference - New opportunities for macromolecule development, delivery and commercialization - 17-18 November 2005, Philadelphia, PA, USA

Craik, D. J. (2006). Peptides and therapeutic proteins - SRI Conference - New opportunities for macromolecule development, delivery and commercialization - 17-18 November 2005, Philadelphia, PA, USA. SRI conference, Philadelphia, 17-18 November 2005. London: Current Drugs Ltd.

Peptides and therapeutic proteins - SRI Conference - New opportunities for macromolecule development, delivery and commercialization - 17-18 November 2005, Philadelphia, PA, USA

2006

Journal Article

theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation

Gallo, S. A., Wang, W., Rawat, S. S., Jung, G., Waring, A. J., Cole, A. M., Lu, H., Yan, X. X., Daly, N. L., Craik, D. J., Jiang, S. B., Lehrer, R. I. and Blumenthal, R. (2006). theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation. Journal of Biological Chemistry, 281 (27), 18787-18792. doi: 10.1074/jbc.M602422200

theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation

2006

Journal Article

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

Gunasekera, S., Daly, N. L., Anderson, M. A. and Craik, D. J. (2006). Chemical synthesis and biosynthesis of the cyclotide family of circular proteins. Iubmb Life, 58 (9), 515-524. doi: 10.1080/15216540600889532

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

2006

Journal Article

CyBase: a database of cyclic protein sequence and structure

Mulvenna, J. P., Wang, C. and Craik, D. J. (2006). CyBase: a database of cyclic protein sequence and structure. Nucleic Acids Research, 34 (Sp. Iss. SI), D192-D194. doi: 10.1093/nar/gkj005

CyBase: a database of cyclic protein sequence and structure