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2006 Journal Article Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporterLovelace, E. S., Armishaw, C. J., Colgrave, M. L., Wahlstrom, M. E., Alewood, P. F., Daly, N. L. and Craik, D. J. (2006). Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. Journal of Medicinal Chemistry, 49 (22), 6561-6568. doi: 10.1021/jm060299h |
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2006 Journal Article NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acidsMarx, U. C., Daly, N. L. and Craik, D. J. (2006). NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids. Magnetic Resonance In Chemistry, 44 (Sp. Iss. SI), S41-S50. doi: 10.1002/mrc.1821 |
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2006 Journal Article Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug designClark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691 |
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2006 Conference Publication Bioengineered cyclic peptides for treatment of multiple sclerosisCemazar, M., Bernard, C. C. and Craik, D. J. (2006). Bioengineered cyclic peptides for treatment of multiple sclerosis. 29th European Peptide Symposium, Gdansk, Poland, 3 - 8 September, 2006. Chichester, England: John Wiley & Sons. doi: 10.1002/psc.797 |
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2006 Journal Article Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?Mulvenna, J. P., Mylne, J. S., Bharathi, R., Burton, R. A., Shirley, N. J., Fincher, G. B., Anderson, M. A. and Craik, D. J. (2006). Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?. Plant Cell, 18 (9), 2134-2144. doi: 10.1105/tpc.106.042812 |
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2006 Journal Article The cyclotides and related macrocyclic peptides as scaffolds in drug designCraik, D. J., Cemazar, M. and Daly, N. L. (2006). The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 9 (2), 251-260. |
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2006 Book Chapter Overview of NMR in the Pharmaceutical SciencesSchirra, H. J. and Craik, D. J. (2006). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance Part 2: Applications in Medical and Pharmaceutical Sciences. (pp. 1177-1184) edited by Graham A. Webb. Netherlands: Springer. |
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2006 Conference Publication Bioengineering cyclic peptides for treatment of multiple sclerosisCemazar, M, Bernard, C and Craik, DJ (2006). Bioengineering cyclic peptides for treatment of multiple sclerosis. 8th International Conference of Neuroimmunology, Nagoya Japan, Oct 15-19, 2006. AMSTERDAM: JOHN WILEY & SONS INC. |
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2006 Conference Publication Animal, Plant and Microbial Toxins - 15th World Congress - 23-28 July 2006, Glasgow, UKCraik, D (2006). Animal, Plant and Microbial Toxins - 15th World Congress - 23-28 July 2006, Glasgow, UK. London: Current Drugs Ltd. |
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2006 Journal Article Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motifDaly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371 |
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2006 Journal Article Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceaeChen, B., Colgrave, M. L., Wang, C. N. and Craik, D. J. (2006). Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Journal of Natural Products, 69 (1), 23-28. doi: 10.1021/np050317i |
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2006 Journal Article The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffoldDaly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200 |
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2006 Journal Article A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stabilityIreland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochemical Journal, 400 (Part 1), 1-12. doi: 10.1042/BJ20060627 |
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2006 Conference Publication Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templatesCraik, David J., Rosengren, K. Johan, Sando, Lillian and Simonsen, Shane S. (2006). Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_101 |
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2006 Journal Article Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motifCemazar, M. and Craik, D. J. (2006). Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif. International Journal of Peptide Research And Therapeutics, 12 (3), 253-260. doi: 10.1007/s10989-006-9019-2 |
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2006 Conference Publication Peptides and therapeutic proteins - SRI Conference - New opportunities for macromolecule development, delivery and commercialization - 17-18 November 2005, Philadelphia, PA, USACraik, D. J. (2006). Peptides and therapeutic proteins - SRI Conference - New opportunities for macromolecule development, delivery and commercialization - 17-18 November 2005, Philadelphia, PA, USA. SRI conference, Philadelphia, 17-18 November 2005. London: Current Drugs Ltd. |
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2006 Journal Article theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formationGallo, S. A., Wang, W., Rawat, S. S., Jung, G., Waring, A. J., Cole, A. M., Lu, H., Yan, X. X., Daly, N. L., Craik, D. J., Jiang, S. B., Lehrer, R. I. and Blumenthal, R. (2006). theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation. Journal of Biological Chemistry, 281 (27), 18787-18792. doi: 10.1074/jbc.M602422200 |
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2006 Journal Article Chemical synthesis and biosynthesis of the cyclotide family of circular proteinsGunasekera, S., Daly, N. L., Anderson, M. A. and Craik, D. J. (2006). Chemical synthesis and biosynthesis of the cyclotide family of circular proteins. Iubmb Life, 58 (9), 515-524. doi: 10.1080/15216540600889532 |
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2006 Journal Article CyBase: a database of cyclic protein sequence and structureMulvenna, J. P., Wang, C. and Craik, D. J. (2006). CyBase: a database of cyclic protein sequence and structure. Nucleic Acids Research, 34 (Sp. Iss. SI), D192-D194. doi: 10.1093/nar/gkj005 |
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2006 Journal Article Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediateCemazar, M., Daly, N. L., Haggblad, S., Lo, K. P., Yulyaningsih, E. and Craik, D. J. (2006). Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate. Journal of Biological Chemistry, 281 (12), 8224-8232. doi: 10.1074/jbc.M513399200 |
