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2008

Conference Publication

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

2008

Conference Publication

Selenocysteine in peptide drug design

Adams, D. J., Alewood, P. F., Choy, P. T., Craik, D. J., Daly, N. L., Grishin, A. A., Hu, S-H., Martin, J. L., Muttenthaler, M., Nevin, S. T., Ngo, S. T. and Noakes, P. G. (2008). Selenocysteine in peptide drug design. Royal Australian Chemical Institute (RACI) Annual Scientific Meeting: Drug Discovery and Development, Couran Cove Island Resort, Queensland, Australia, 13 - 17 July 2008.

Selenocysteine in peptide drug design

2008

Journal Article

Cyclotides and conotoxins ultra-stable disulfide-rich peptides

Craik, David J., Clark, Richard J. and Daly, Norelle L. (2008). Cyclotides and conotoxins ultra-stable disulfide-rich peptides. Chimica Oggi -Chemistry Today, 26 (4), 20-22.

Cyclotides and conotoxins ultra-stable disulfide-rich peptides

2008

Journal Article

Biosynthesis of circular proteins in plants

Gillon, Amanda D, Saska, Ivana, Jennings, Cameron V., Guarino, Rosemary F., Craik, David J. and Anderson, Marilyn A. (2008). Biosynthesis of circular proteins in plants. The Plant Journal, 53 (3), 505-515. doi: 10.1111/j.1365-313X.2007.03357.x

Biosynthesis of circular proteins in plants

2008

Conference Publication

The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design

Craik, David, Saska, Ivana, Gruber, Christian, Gillon, Amanda and Anderson, Marilyn (2008). The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1089

The biosynthesis and evolution of cyclotides: macrocyclic peptides from plants, with applications in drug design

2007

Journal Article

Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?

Nevin, Simon T., Clark, Richard J., Klimis, H., Christie, M. J., Craik, David J. and Adams, David J. (2007). Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?. Molecular Pharmacology, 72 (6), 1406-1410. doi: 10.1124/mol.107.040568

Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?

2007

Journal Article

An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization

Saska, Ivana, Gillon, Amanda D., Hatsugai, Noriyuki, Dietzgen, Ralf G., Hara-Hishimura, Ikuko, Anderson, Marilyn A. and Craik, David J. (2007). An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization. Journal of Biological Chemistry, 282 (40), 29721-29728. doi: 10.1074/jbc.M705185200

An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization

2007

Journal Article

Chemical modification of conotoxins to improve stability and activity

Craik, David J. and Adams, David J. (2007). Chemical modification of conotoxins to improve stability and activity. ACS Chemical Biology, 2 (7), 457-468. doi: 10.1021/cb700091j

Chemical modification of conotoxins to improve stability and activity

2007

Journal Article

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

2007

Journal Article

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

2007

Journal Article

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

Craik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

2007

Conference Publication

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

Craik, D. J. (2007). American Peptide Society - 20th Symposium: Peptide vaccine and drug development. American Peptide Society: 20th Symposium, Montreal, Canada, 26-30 June 2007. Nottingham, United Kingdom: Current Drugs.

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

2007

Journal Article

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

Gruber, C. W, Cemazar, M., Clark, R. .J, Horibe, T, Renda, R. F., Anderson, M. A. and Craik, D. J. (2007). A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins. Journal of Biological Chemistry, 282 (28), 20435-20446. doi: 10.1074/jbc.M700018200

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

2007

Journal Article

NMR as a tool for elucidating the structures of circular and knotted proteins

Craik, D. J and Daly, N. L (2007). NMR as a tool for elucidating the structures of circular and knotted proteins. Molecular Biosystems, 3 (4), 257-265. doi: 10.1039/b616856f

NMR as a tool for elucidating the structures of circular and knotted proteins

2007

Journal Article

The chemistry and biology of cyclotides

Craik, D. J., Cemazar, M. and Daly, N. L. (2007). The chemistry and biology of cyclotides. Current Opinion In Drug Discovery & Development, 10 (2), 176-184.

The chemistry and biology of cyclotides

2007

Journal Article

The discovery and development of a natural combinatorial peptide template: the cyclotides

Ireland, DC and Craik, DJ (2007). The discovery and development of a natural combinatorial peptide template: the cyclotides. Biopolymers, 88 (4), 540-540.

The discovery and development of a natural combinatorial peptide template: the cyclotides

2007

Journal Article

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis

Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis. International Journal of Biochemistry & Cell Biology, 39 (12), 2252-2264. doi: 10.1016/j.biocel.2007.06.016

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis

2007

Journal Article

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

Cemazar, M, Bernard, CCA and Craik, DJ (2007). Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis. Biopolymers, 88 (4), 523-523.

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

2007

Conference Publication

The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis

Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007 . Hoboken, NJ, United States: John Wiley & Sons.

The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis