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2008

Book Chapter

Structure-based Drug Design and NMR-based screening

Craik, D. J. and Clark, R. J. (2008). Structure-based Drug Design and NMR-based screening. Pharmacology from drug development to gene therapy. (pp. 225-313) edited by R. A. Meyers. Weinheim: Wiley-VCH Verlag GMBH & Co.

Structure-based Drug Design and NMR-based screening

2008

Journal Article

Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

Aboye, T, Clark, Richard J., Craik, David J. and Goransson, U (2008). Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. ChemBioChem, 9 (1), 103-113. doi: 10.1002/cbic.200700357

Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

2008

Conference Publication

Selenocysteine in peptide folding and drug design

Muttenthaler, M., Nevin, S. T., Grishin, A. A., Ngo, S. T., Choy, P. T., Daly, N. L., Hu, S-H., Martin, J. L., Noakes, P. G., Craik, D. J., Adams, D. J. and Alewood, P. F. (2008). Selenocysteine in peptide folding and drug design. XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Vienna, Austria, 31 August - 4 September 2008.

Selenocysteine in peptide folding and drug design

2008

Journal Article

Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis

Wang, Conan K. L., Colgrave, Michelle L., Gustafson, Kirk R., Ireland, David C., Goransson, Ulf and Craik, David J. (2008). Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis. Journal of Natural Products, 71 (1), 47-52. doi: 10.1021/np070393g

Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis

2008

Conference Publication

Understanding the structure/activity relationships of hepcidin

Clark, Richard, Tan, Chia Chia, Nemeth, Elizabeta, Ganz, Thomas and Craik, David (2008). Understanding the structure/activity relationships of hepcidin. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090

Understanding the structure/activity relationships of hepcidin

2008

Journal Article

Cyclotides as natural anti-HIV agents

Ireland, David C., Wang, Conan K., Wilson, Jennifer A., Gustafson, Kirk R. and Craik, David J. (2008). Cyclotides as natural anti-HIV agents. Biopolymers: Peptide Science, 90 (1), 51-60. doi: 10.1002/bip.20886

Cyclotides as natural anti-HIV agents

2008

Conference Publication

Structural Aspects of Hepcidin-Ferroportin Binding

Preza, G, Fernandes, A, Clark, RJ, Craik, DJ, Ganz, T and Nemeth, E (2008). Structural Aspects of Hepcidin-Ferroportin Binding. 50th Annual Meeting of the American- Society-of-Hematology, San Francisco Ca, Dec 06-09, 2008. WASHINGTON: AMER SOC HEMATOLOGY.

Structural Aspects of Hepcidin-Ferroportin Binding

2008

Conference Publication

A combined chemistry and biology approach to the development of novel agents for protection against livestock pests

Huang, Yen-Hua, Colgrave, Michelle L., Kotze, Andrew C. and Craik, David J. (2008). A combined chemistry and biology approach to the development of novel agents for protection against livestock pests. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090

A combined chemistry and biology approach to the development of novel agents for protection against livestock pests

2008

Journal Article

Microwave-assisted Boc-solid phase peptide synthesis of cyclic cysteine-rich peptide

Cemazar, Masa and Craik, David J. (2008). Microwave-assisted Boc-solid phase peptide synthesis of cyclic cysteine-rich peptide. Journal of Peptide Science, 14 (6), 683-689. doi: 10.1002/psc.972

Microwave-assisted Boc-solid phase peptide synthesis of cyclic cysteine-rich peptide

2008

Conference Publication

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090

Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2

2007

Journal Article

Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?

Nevin, Simon T., Clark, Richard J., Klimis, H., Christie, M. J., Craik, David J. and Adams, David J. (2007). Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?. Molecular Pharmacology, 72 (6), 1406-1410. doi: 10.1124/mol.107.040568

Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?

2007

Journal Article

An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization

Saska, Ivana, Gillon, Amanda D., Hatsugai, Noriyuki, Dietzgen, Ralf G., Hara-Hishimura, Ikuko, Anderson, Marilyn A. and Craik, David J. (2007). An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization. Journal of Biological Chemistry, 282 (40), 29721-29728. doi: 10.1074/jbc.M705185200

An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization

2007

Journal Article

Chemical modification of conotoxins to improve stability and activity

Craik, David J. and Adams, David J. (2007). Chemical modification of conotoxins to improve stability and activity. ACS Chemical Biology, 2 (7), 457-468. doi: 10.1021/cb700091j

Chemical modification of conotoxins to improve stability and activity

2007

Journal Article

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

2007

Journal Article

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

Seydel, P., Gruber, C., Craik, D. J. and Dörnenburg, H. (2007). Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures. Applied Microbiology and Biotechnology, 77 (2), 275-284. doi: 10.1007/s00253-007-1159-6

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

2007

Conference Publication

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

Gruber, G. W., Cemazar, M., Clark, R., Horibe, T., Renda, R., Anderson, M. A. and Craik, D. J. (2007). Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides. 20th American-Peptide-Society Symposium, Montréal, Canada, 26-30 Jun 2007. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.20783

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

2007

Journal Article

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

Plan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

2007

Journal Article

Insecticidal plant cyclotides and related cystine knot toxins

Gruber, C. W, Cemazar, M., Anderson, MA and Craik, D. J (2007). Insecticidal plant cyclotides and related cystine knot toxins. Toxicon, 49 (4), 561-575. doi: 10.1016/j.toxicon.2006.11.018

Insecticidal plant cyclotides and related cystine knot toxins

2007

Journal Article

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin