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2007

Journal Article

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

Cemazar, M, Bernard, CCA and Craik, DJ (2007). Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis. Biopolymers, 88 (4), 523-523.

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

2007

Journal Article

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

Plan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

2007

Journal Article

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

Seydel, P., Gruber, C., Craik, D. J. and Dörnenburg, H. (2007). Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures. Applied Microbiology and Biotechnology, 77 (2), 275-284. doi: 10.1007/s00253-007-1159-6

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

2007

Conference Publication

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

Gruber, G. W., Cemazar, M., Clark, R., Horibe, T., Renda, R., Anderson, M. A. and Craik, D. J. (2007). Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides. 20th American-Peptide-Society Symposium, Montréal, Canada, 26-30 Jun 2007. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.20783

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

2007

Journal Article

Insecticidal plant cyclotides and related cystine knot toxins

Gruber, C. W, Cemazar, M., Anderson, MA and Craik, D. J (2007). Insecticidal plant cyclotides and related cystine knot toxins. Toxicon, 49 (4), 561-575. doi: 10.1016/j.toxicon.2006.11.018

Insecticidal plant cyclotides and related cystine knot toxins

2007

Journal Article

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

2007

Journal Article

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

Gruber, C. W, Cemazar, M., Clark, R. .J, Horibe, T, Renda, R. F., Anderson, M. A. and Craik, D. J. (2007). A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins. Journal of Biological Chemistry, 282 (28), 20435-20446. doi: 10.1074/jbc.M700018200

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

2007

Journal Article

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

Craik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

2007

Conference Publication

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

Craik, D. J. (2007). American Peptide Society - 20th Symposium: Peptide vaccine and drug development. American Peptide Society: 20th Symposium, Montreal, Canada, 26-30 June 2007. Nottingham, United Kingdom: Current Drugs.

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

2006

Journal Article

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

Rosengren, K. Johan, Daly, Norelle L., Fornander, Liselotte M., Jonsson, Linda M. H., Shirafuji, Yoshinori, Qu, Xiaoqing, Vogel, Hans J., Ouellette, Andre J. and Craik, David J. (2006). Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4. Journal of Biological Chemistry, 281 (38), 28068-28078. doi: 10.1074/jbc.M604992200

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

2006

Journal Article

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

2006

Journal Article

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability

Ireland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability. Journal of Peptide Science, 12 (S1), 143-143. doi: 10.1002/psc.797

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability

2006

Journal Article

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

Rosengren, K. J., Zhang, S., Lin, F., Daly, N. L., Scott, D. J., Hughes, R. A., Bathgate, R. A. D., Craik, D. J. and Wade, J. D. (2006). Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3. Journal of Biological Chemistry, 281 (38), 28287-28295. doi: 10.1074/jbc.M603829200

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

2006

Journal Article

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

Armishaw, Christopher J., Daly, Norelle L., Nevin, Simon T., Adams, David J., Craik, David J. and Alewood, Paul F. (2006). Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists. Journal of Biological Chemistry, 281 (20), 14136-14143. doi: 10.1074/jbc.M512419200

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

2006

Journal Article

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

Ireland, David C., Colgrave, Michelle L., Nguyencong, Philip, Daly, Norelle L. and Craik, David J. (2006). Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins. Journal of Molecular Biology, 357 (5), 1522-1535. doi: 10.1016/j.jmb.2006.01.051

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

2006

Journal Article

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

Rosengren, K. J., Lin, F., Bathgate, R. A. D., Tregear, G. W., Daly, N. L., Wade, J. D. and Craik, D. J. (2006). Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3. Journal of Biological Chemistry, 281 (9), 5845-5851. doi: 10.1074/jbc.M511210200

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

2006

Conference Publication

Bioengineered cyclic peptides for treatment of multiple sclerosis

Cemazar, M., Bernard, C. C. and Craik, D. J. (2006). Bioengineered cyclic peptides for treatment of multiple sclerosis. 29th European Peptide Symposium, Gdansk, Poland, 3 - 8 September, 2006. Chichester, England: John Wiley & Sons. doi: 10.1002/psc.797

Bioengineered cyclic peptides for treatment of multiple sclerosis

2006

Journal Article

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

Mulvenna, J. P., Mylne, J. S., Bharathi, R., Burton, R. A., Shirley, N. J., Fincher, G. B., Anderson, M. A. and Craik, D. J. (2006). Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?. Plant Cell, 18 (9), 2134-2144. doi: 10.1105/tpc.106.042812

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

2006

Journal Article

The cyclotides and related macrocyclic peptides as scaffolds in drug design

Craik, D. J., Cemazar, M. and Daly, N. L. (2006). The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 9 (2), 251-260.

The cyclotides and related macrocyclic peptides as scaffolds in drug design