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2007

Journal Article

Chemical modification of conotoxins to improve stability and activity

Craik, David J. and Adams, David J. (2007). Chemical modification of conotoxins to improve stability and activity. ACS Chemical Biology, 2 (7), 457-468. doi: 10.1021/cb700091j

Chemical modification of conotoxins to improve stability and activity

2007

Journal Article

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28

Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics

2007

Journal Article

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

2007

Journal Article

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

Gruber, C. W, Cemazar, M., Clark, R. .J, Horibe, T, Renda, R. F., Anderson, M. A. and Craik, D. J. (2007). A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins. Journal of Biological Chemistry, 282 (28), 20435-20446. doi: 10.1074/jbc.M700018200

A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins

2007

Journal Article

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

Craik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

2007

Conference Publication

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

Craik, D. J. (2007). American Peptide Society - 20th Symposium: Peptide vaccine and drug development. American Peptide Society: 20th Symposium, Montreal, Canada, 26-30 June 2007. Nottingham, United Kingdom: Current Drugs.

American Peptide Society - 20th Symposium: Peptide vaccine and drug development

2007

Journal Article

NMR as a tool for elucidating the structures of circular and knotted proteins

Craik, D. J and Daly, N. L (2007). NMR as a tool for elucidating the structures of circular and knotted proteins. Molecular Biosystems, 3 (4), 257-265. doi: 10.1039/b616856f

NMR as a tool for elucidating the structures of circular and knotted proteins

2007

Journal Article

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis

Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis. International Journal of Biochemistry & Cell Biology, 39 (12), 2252-2264. doi: 10.1016/j.biocel.2007.06.016

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis

2007

Journal Article

The chemistry and biology of cyclotides

Craik, D. J., Cemazar, M. and Daly, N. L. (2007). The chemistry and biology of cyclotides. Current Opinion In Drug Discovery & Development, 10 (2), 176-184.

The chemistry and biology of cyclotides

2007

Journal Article

The discovery and development of a natural combinatorial peptide template: the cyclotides

Ireland, DC and Craik, DJ (2007). The discovery and development of a natural combinatorial peptide template: the cyclotides. Biopolymers, 88 (4), 540-540.

The discovery and development of a natural combinatorial peptide template: the cyclotides

2007

Conference Publication

The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis

Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007 . Hoboken, NJ, United States: John Wiley & Sons.

The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis

2007

Journal Article

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

Cemazar, M, Bernard, CCA and Craik, DJ (2007). Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis. Biopolymers, 88 (4), 523-523.

Sequential overlapping fractionation (SOFT) approach to molecular grafting yields novel cyclic peptides for the treatment of multiple sclerosis

2007

Journal Article

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

Plan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097

The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides

2007

Journal Article

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

Seydel, P., Gruber, C., Craik, D. J. and Dörnenburg, H. (2007). Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures. Applied Microbiology and Biotechnology, 77 (2), 275-284. doi: 10.1007/s00253-007-1159-6

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

2007

Conference Publication

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

Gruber, G. W., Cemazar, M., Clark, R., Horibe, T., Renda, R., Anderson, M. A. and Craik, D. J. (2007). Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides. 20th American-Peptide-Society Symposium, Montréal, Canada, 26-30 Jun 2007. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.20783

Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides

2007

Journal Article

Insecticidal plant cyclotides and related cystine knot toxins

Gruber, C. W, Cemazar, M., Anderson, MA and Craik, D. J (2007). Insecticidal plant cyclotides and related cystine knot toxins. Toxicon, 49 (4), 561-575. doi: 10.1016/j.toxicon.2006.11.018

Insecticidal plant cyclotides and related cystine knot toxins

2006

Journal Article

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

Rosengren, K. Johan, Daly, Norelle L., Fornander, Liselotte M., Jonsson, Linda M. H., Shirafuji, Yoshinori, Qu, Xiaoqing, Vogel, Hans J., Ouellette, Andre J. and Craik, David J. (2006). Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4. Journal of Biological Chemistry, 281 (38), 28068-28078. doi: 10.1074/jbc.M604992200

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

2006

Journal Article

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

2006

Journal Article

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability

Ireland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability. Journal of Peptide Science, 12 (S1), 143-143. doi: 10.1002/psc.797

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability