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2020 Journal Article A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functionsAzimi, Iman, Stevenson, Ralph J., Zhang, Xuexin, Meizoso-Huesca, Aldo, Xin, Ping, Johnson, Martin, Flanagan, Jack U., Chalmers, Silke B., Yoast, Ryan E., Kapure, Jeevak S., Ross, Benjamin P., Vetter, Irina, Ashton, Mark R., Launikonis, Bradley S., Denny, William A., Trebak, Mohamed and Monteith, Gregory R. (2020). A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions. ACS Pharmacology and Translational Science, 3 (1) acsptsci.9b00081, 135-147. doi: 10.1021/acsptsci.9b00081 |
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2017 Journal Article Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cellsPeters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Wiegmans, A. P., Lim, H. F., Milevskiy, M. J. G., Azimi, I., Davis, F. M., Northwood, K. S., Pera, E., Marcial, D. L., Dray, E., Waterhouse, N. J., Cabot, P. J., Gonda, T. J., Kenny, P. A., Brown, M. A., Khanna, K. K., Roberts-Thomson, S. J. and Monteith, G. R. (2017). Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells. Oncogene, 36 (46), 6490-6500. doi: 10.1038/onc.2017.234 |
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2017 Journal Article The calcium-cancer signalling nexusMonteith, Gregory R., Prevarskaya, Natalia and Roberts-Thomson, Sarah J. (2017). The calcium-cancer signalling nexus. Nature Reviews Cancer, 17 (6), 367-380. doi: 10.1038/nrc.2017.18 |
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2014 Journal Article Targeting EMT in cancer: opportunities for pharmacological interventionDavis, Felicity M., Stewart, Teneale A., Thompson, Erik W. and Monteith, Gregory R. (2014). Targeting EMT in cancer: opportunities for pharmacological intervention. Trends in Pharmacological Sciences, 35 (9), 479-488. doi: 10.1016/j.tips.2014.06.006 |
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2014 Journal Article Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependentDavis, F. M., Azimi, I., Faville, R. A., Peters, A. A., Jalink, K., Putney Jr, J. W., Goodhill, G. J., Thompson, E. W., Roberts-Thomson, S. J. and Monteith, G. R. (2014). Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene, 33 (18), 2307-2316. doi: 10.1038/onc.2013.187 |
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2010 Journal Article Store-independent activation of Orai1 by SPCA2 in mammary tumorsFeng, Mingye, Grice, Desma, Faddy, Helen, Nguyen, Nguyen, Leitch, Sharon, Wang, Yingyu, Muend, Sabina, Kenny, Paraic A, Sukumar, Saraswati, Roberts-Thomson, Sarah J., Monteith, Gregory R. and Rao, Rajini (2010). Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell, 143 (1), 84-98. doi: 10.1016/j.cell.2010.08.040 |
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2007 Journal Article Calcium and cancer: targeting Ca2+ transportMonteith, Gregory R., McAndrew, Damara, Faddy, Helen M. and Roberts-Thomson, Sarah J. (2007). Calcium and cancer: targeting Ca2+ transport. Nature Reviews Cancer, 7 (7), 519-530. doi: 10.1038/nrc2171 |
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2020 Journal Article Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cellsAzimi, Iman, Robitaille, Mélanie, Armitage, Kaela, So, Choon Leng, Milevskiy, Michael J. G., Northwood, Korinne, Lim, Huai Fang, Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cells. International Journal of Molecular Sciences, 21 (24) 9417, 1-14. doi: 10.3390/ijms21249417 |
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2020 Journal Article Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancyTaylor, Jack, Azimi, Iman, Monteith, Gregory and Bebawy, Mary (2020). Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy. Journal of Extracellular Vesicles, 9 (1) 1734326, 1734326. doi: 10.1080/20013078.2020.1734326 |
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2020 Journal Article Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cellsBong, Alice H.L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 522 (2), 532-538. doi: 10.1016/j.bbrc.2019.11.136 |
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2020 Journal Article Transient receptor potential cation channel subfamily V and breast cancerSo, Choon Leng, Milevskiy, Michael J. G. and Monteith, Gregory R. (2020). Transient receptor potential cation channel subfamily V and breast cancer. Laboratory Investigation, 100 (2), 199-206. doi: 10.1038/s41374-019-0348-0 |
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2020 Journal Article Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuliStewart, Teneale A., Azimi, Iman, Marcial, Daneth, Peters, Amelia A., Chalmers, Silke B., Yapa, Kunsala T. D. S, Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli. Laboratory Investigation, 100 (2), 224-233. doi: 10.1038/s41374-019-0280-3 |
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2019 Journal Article NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicinBong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Molecular Oncology, 14 (1) 1878-0261.12589, 87-104. doi: 10.1002/1878-0261.12589 |
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2019 Journal Article Calcium signalling and breast cancerSo, Choon Leng, Saunus, Jodi M., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Calcium signalling and breast cancer. Seminars in Cell & Developmental Biology, 94, 74-83. doi: 10.1016/j.semcdb.2018.11.001 |
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2019 Journal Article The calcium-signaling toolkit in cancer: remodeling and targetingRoberts-Thomson, Sarah J., Chalmers, Silke B. and Monteith, Gregory R. (2019). The calcium-signaling toolkit in cancer: remodeling and targeting. Cold Spring Harbor Perspectives in Biology, 11 (8) a035204, a035204. doi: 10.1101/cshperspect.a035204 |
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2019 Journal Article ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responsesAzimi, Iman, Milevskiy, Michael J. G., Chalmers, Silke B., Yapa, Kunsala T. D. S., Robitaille, Mélanie, Henry, Christopher, Baillie, Gregory J., Thompson, Erik W., Roberts-Thomson, Sarah J and Monteith, Gregory R (2019). ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses. Cancers, 11 (2) 208, 208. doi: 10.3390/cancers11020208 |
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2018 Journal Article Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferationAzimi, Iman, Bong, Alice H., Poo, Greta X. H., Armitage, Kaela, Lok, Dawn, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation. Cellular and Molecular Life Sciences, 75 (24), 4525-4537. doi: 10.1007/s00018-018-2904-y |
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2018 Journal Article ORAI channels and cancerChalmers, Silke B. and Monteith, Gregory R. (2018). ORAI channels and cancer. Cell Calcium, 74, 160-167. doi: 10.1016/j.ceca.2018.07.011 |
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2018 Journal Article An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assayStevenson, Ralph J, Azimi, Iman, Flanagan, Jack U, Inserra, Marco, Vetter, Irina, Monteith, Gregory R and Denny, William A (2018). An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay. Bioorganic & Medicinal Chemistry, 26 (12), 3406-3413. doi: 10.1016/j.bmc.2018.05.012 |
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2018 Journal Article An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cellsKaemmerer, Elke, Turner, Dane, Peters, Amelia A., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells. Journal of pharmacological and toxicological methods, 92, 13-19. doi: 10.1016/j.vascn.2018.02.005 |
