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2024

Journal Article

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2

Rahaman, Md. Habibur, Thygesen, Sara J., Maxwell, Michael J., Kim, Hyoyoung, Mudai, Prerna, Nanson, Jeffrey D., Jia, Xinying, Vajjhala, Parimala R., Hedger, Andrew, Vetter, Irina, Haselhorst, Thomas, Robertson, Avril A. B., Dymock, Brian, Ve, Thomas, Mobli, Mehdi, Stacey, Katryn J. and Kobe, Bostjan (2024). o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2. Journal of Enzyme Inhibition and Medicinal Chemistry, 39 (1) 2313055, 2313055. doi: 10.1080/14756366.2024.2313055

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2

2024

Journal Article

Mixed-organism enzyme in plant defense

Thynne, Elisha and Kobe, Bostjan (2024). Mixed-organism enzyme in plant defense. Science, 383 (6684), 707-708. doi: 10.1126/science.adn8306

Mixed-organism enzyme in plant defense

2024

Journal Article

Hfe permease and Haemophilus influenzae manganese homeostasis

Ganio, Katherine, Nasreen, Marufa, Yang, Zihao, Maunders, Eve A., Luo, Zhenyao, Hossain, Sheikh Imamul, Ngu, Dalton H. Y., Ellis, Daniel, Gu, Jin, Neville, Stephanie L., Wilksch, Jonathan, Gunn, Adam P., Whittall, Jonathan J., Kobe, Boštjan, Deplazes, Evelyne, Kappler, Ulrike and McDevitt, Christopher A. (2024). Hfe permease and Haemophilus influenzae manganese homeostasis. ACS Infectious Diseases, 10 (2), 436-452. doi: 10.1021/acsinfecdis.3c00407

Hfe permease and Haemophilus influenzae manganese homeostasis

2024

Journal Article

TIR-mediated immune signalling through the EDS1:PAD4:ADR1 node is conserved in monocots and dicots

Maruta, Natsumi, Sorbello, Mitchell and Kobe, Bostjan (2024). TIR-mediated immune signalling through the EDS1:PAD4:ADR1 node is conserved in monocots and dicots. Molecular Plant, 18 (2), 192-194. doi: 10.1016/j.molp.2024.12.017

TIR-mediated immune signalling through the EDS1:PAD4:ADR1 node is conserved in monocots and dicots

2023

Journal Article

Mildew RALPHs up in arms with cereals

Maruta, Natsumi, Outram, Megan A. and Kobe, Bostjan (2023). Mildew RALPHs up in arms with cereals. Proceedings of the National Academy of Sciences, 120 (36) e2311817120, 1-3. doi: 10.1073/pnas.2311817120

Mildew RALPHs up in arms with cereals

2023

Conference Publication

Structural and functional characterisation of plant TIR domains and their role in plant innate immunity

Lim, Bryan Y. J., Sorbello, Mitchell, Ngu, Dalton H. Y., Burdett, Hayden, Maruta, Natsumi and Kobe, Boštjan (2023). Structural and functional characterisation of plant TIR domains and their role in plant innate immunity. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087752

Structural and functional characterisation of plant TIR domains and their role in plant innate immunity

2023

Conference Publication

Development of 3D-ED/MicroED facility at the University of Queensland

Arachchige, K. S. A., Koifman, N., Gu, W., Kobe, B., Clegg, J. K., Xu, H. and Wepf, R. (2023). Development of 3D-ED/MicroED facility at the University of Queensland. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086461

Development of 3D-ED/MicroED facility at the University of Queensland

2023

Conference Publication

Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins

Qian, Xiaoqi, Nanson, Jeffrey and Kobe, Boštjan (2023). Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s205327332308662x

Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins

2023

Conference Publication

Activated bacterial TIR proteins: NADase activity and filamentous assemblies

Li, Sulin, Manik, Mohammad Kawsar, Ve, Thomas, Nanson, Jeffrey D. and Kobe, Bostjan (2023). Activated bacterial TIR proteins: NADase activity and filamentous assemblies. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086904

Activated bacterial TIR proteins: NADase activity and filamentous assemblies

2023

Conference Publication

Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1

Shi, Y., Nanson, J., Gu, W., Masic, V., Mosaiab, T., Landsberg, M., Kobe, B. and Ve, T. (2023). Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087776

Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1

2023

Conference Publication

Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis

Ngu, Dalton H. Y., Maunders, Eve. A., Lim, Bryan Y. J., Luo, Zhenyao, McDevitt, Christopher A. and Kobe, Boštjan (2023). Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323089477

Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis

2023

Conference Publication

TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways

Nanson, J. D., Muusse, T. W., Li, Y., Pan, M., Landsberg, M. J., Vajjhala, P. R., Ve, T., Stacey, K. J. and Kobe, B. (2023). TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086631

TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways

2023

Conference Publication

Structural and functional characterization of interleukin-1 receptor 8

Alenzi, Athyah, Nimma, Surekha and Kobe, Bostjan (2023). Structural and functional characterization of interleukin-1 receptor 8. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086667

Structural and functional characterization of interleukin-1 receptor 8

2023

Conference Publication

Structural and functional characterisation of plant innate immune receptors

Maruta, Natsumi, Burdett, Hayden, Sorbello, Mitchell, Lim, Bryan Ying Jie, Ngu, Dalton and Kobe, Bostjan (2023). Structural and functional characterisation of plant innate immune receptors. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087764

Structural and functional characterisation of plant innate immune receptors

2023

Conference Publication

Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology

Kobe, Bostjan, Nanson, Jeffrey D., Manik, Mohammad K., Li, Sulin, Gu, Weixi, Pan, Mengqi, Li, Yan, Muusse, Timothy W., Vajjhala, Parimala R, Stacey, Katryn J., Holmes, Susannah, Darmanin, Connie, Clabbers, Max T. B., Xu, Hongyi, Shi, Yun and Ve, Thomas (2023). Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323093658

Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology

2023

Conference Publication

Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration

McGuinness, Helen Ying, Rosell, Arnau Llobert, Gu, Weixi, Nanson, Jeffrey, Ve, Thomas and Kobe, Bostjan (2023). Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087661

Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration

2023

Conference Publication

Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED)

Li, Y., Nanson, J. D., Pacoste, L. C., Xu, H. and Kobe, B. (2023). Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED). XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323093993

Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED)

2023

Conference Publication

Allosteric regulation of SARM1, the executioner of axon degeneration

Gu, W., Luo, Z., Nanson, J. D., Ve, T. and Kobe, B. (2023). Allosteric regulation of SARM1, the executioner of axon degeneration. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323089398

Allosteric regulation of SARM1, the executioner of axon degeneration

2023

Conference Publication

Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers

Kwah, Kayden, Gu, Weixi, Arachchige, Kasun S. A., He, Yaowu, Landsberg, Michael, Kobe, Bostjan and Hooper, John (2023). Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323084449

Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers

2023

Journal Article

Toll/interleukin-1 receptor domains in bacterial and plant immunity

Li, Sulin, Manik, Mohammad K., Shi, Yun, Kobe, Bostjan and Ve, Thomas (2023). Toll/interleukin-1 receptor domains in bacterial and plant immunity. Current Opinion in Microbiology, 74 102316, 1-10. doi: 10.1016/j.mib.2023.102316

Toll/interleukin-1 receptor domains in bacterial and plant immunity