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2015 Journal Article Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcALuo, Zhenyao, Morey, Jacqueline R., McDevitt, Christopher A. and Kobe, Bostjan (2015). Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA. Acta Crystallographica: Section F Structural Biology Communications, 71 (12), 1459-1464. doi: 10.1107/S2053230X15021330 |
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2015 Journal Article Characterizing the conformational dynamics of metal-free PsaA usingmolecular dynamics simulations and electron paramagnetic resonance spectroscopyDeplazes, Evelyne, Begg, Stephanie L., van Wonderen, Jessica H., Campbell, Rebecca, Kobe, Bostjan, Paton, James C., MacMillan, Fraser, McDevitt, Christopher A. and O'Mara, Megan L. (2015). Characterizing the conformational dynamics of metal-free PsaA usingmolecular dynamics simulations and electron paramagnetic resonance spectroscopy. Biophysical Chemistry, 207, 51-60. doi: 10.1016/j.bpc.2015.08.004 |
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2015 Journal Article Computer-aided design of T-cell epitope-based vaccines: addressing population coverageOyarzun, P. and Kobe, B. (2015). Computer-aided design of T-cell epitope-based vaccines: addressing population coverage. International Journal of Immunogenetics, 42 (5), 313-321. doi: 10.1111/iji.12214 |
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2015 Journal Article Structural and biochemical analysis of a single amino-acid mutant of WzzBSF that alters Lipopolysaccharide O-antigen chain length in Shigella flexneriChang, Chiung-Wen, Tran, Elizabeth N. H., Ericsson, Daniel J., Casey, Lachlan W., Lonhienne, Thierry, Benning, Friederike, Morona, Renato and Kobe, Bostjan (2015). Structural and biochemical analysis of a single amino-acid mutant of WzzBSF that alters Lipopolysaccharide O-antigen chain length in Shigella flexneri. PLoS One, 10 (9) e0138266, e0138266. doi: 10.1371/journal.pone.0138266 |
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2015 Journal Article Fusion-protein-assisted protein crystallizationKobe, Bostjan, Ve, Thomas and Williams, Simon J. (2015). Fusion-protein-assisted protein crystallization. Acta Crystallographica. Section F Structural Biology Communications, 71 (7), 861-869. doi: 10.1107/S2053230X15011061 |
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2015 Journal Article Stability of the octameric structure affects plasminogen-binding capacity of Streptococcal enolaseCork, Amanda J., Ericsson, Daniel J., Law, Ruby H. P., Casey, Lachlan W., Valkov, Eugene, Bertozzi, Carlo, Stamp, Anna, Jovcevski, Blagojce, Aquilina, J. Andrew, Whisstock, James C., Walker, Mark J. and Kobe, Bostjan (2015). Stability of the octameric structure affects plasminogen-binding capacity of Streptococcal enolase. PLoS One, 10 (3) e0121764, 1-18. doi: 10.1371/journal.pone.0121764 |
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2015 Journal Article Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniaeBegg, Stephanie L., Eijkelkamp, Bart A., Luo, Zhenyao, Couñago, Rafael M., Morey, Jacqueline R., Maher, Megan J., Ong, Cheryl-lynn Y., McEwan, Alastair G., Kobe, Bostjan, O'Mara, Megan L., Paton, James C. and McDevitt, Christopher A. (2015). Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nature Communications, 6 (6418) 6418, 1-11. doi: 10.1038/ncomms7418 |
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2015 Journal Article A linker strategy for the production and crystallization of Toll/interleukin-1 receptor/resistance protein domain complexesWilliams, Simon J., Ve, Thomas and Kobe, Bostjan (2015). A linker strategy for the production and crystallization of Toll/interleukin-1 receptor/resistance protein domain complexes. Protein Engineering, Design and Selection, 28 (5), 137-145. doi: 10.1093/protein/gzv013 |
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2015 Journal Article Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approachBajaj, Megha, Mamidyala, Sreeman K., Zuegg, Johannes, Begg, Stephanie L., Ween, Miranda P., Luo, Zhenyao, Huang, Johnny Xiao, McEwan, Alastair G., Kobe, Bostjan, Paton, James C., McDevitt, Christopher A. and Cooper, Matthew A. (2015). Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach. ACS Chemical Biology, 10 (6), 1511-1520. doi: 10.1021/cb501032x |
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2015 Journal Article TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation.Thakar, Nilay Y., Ovchinnikov, Dmitry A., Hastie, Marcus L., Kobe, Bostjan, Gorman, Jeffrey J. and Wolvetang, Ernst J. (2015). TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation.. Molecular Biology of the Cell, 26 (5), 993-1006. doi: 10.1091/mbc.E14-08-1290 |
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2015 Journal Article A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: Application to emerging infectious diseases.Oyarzun, Patricio, Ellis, Jonathan J., Gonzalez-Galarza, Faviel F., Jones, Andrew R, Middleton, Derek, Boden, Mikael and Kobe, Bostjan (2015). A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: Application to emerging infectious diseases.. Vaccine, 33 (10), 1267-1273. doi: 10.1016/j.vaccine.2015.01.040 |
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2014 Journal Article Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains.Ve, Thomas, Williams, Simon J. and Kobe, Bostjan (2014). Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains.. Apoptosis, 20 (2), 250-261. doi: 10.1007/s10495-014-1064-2 |
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2014 Journal Article Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylationRoona, Gergely, Borsos, Mate, Ellis, Jonathan J., Mehdi, Ahmed M., Christie, Mary, Koornyei, Zsuzsanna, Neubrandt, Mate, Tooth, Judit, Bozooky, Zoltan, Buday, Laszlo, Madaraasz, Emilia, Bodaen, Mikael, Kobe, Bostjan and Veertessy, Beata G. (2014). Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation. Cell Cycle, 13 (22), 3551-3564. doi: 10.4161/15384101.2014.960740 |
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2014 Journal Article Diversity and variability of NOD-like receptors in fungiDyrka, Witold, Lamacchia, Marina, Durrens, Pascal, Kobe, Bostjan, Daskalov, Asen, Paoletti, Matthieu, Sherman, David J. and Saupe, Sven J. (2014). Diversity and variability of NOD-like receptors in fungi. Genome Biology and Evolution, 6 (12), 3137-3158. doi: 10.1093/gbe/evu251 |
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2014 Journal Article Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in toll-like receptor and interferon signalingObayed Ullah, M., Valkov, Eugene, Ve, Thomas, Williams, Simon, Mas, Caroline, Mansell, Ashley and Kobe, Bostjan (2014). Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in toll-like receptor and interferon signaling. Protein Expression and Purification, 106, 31-40. doi: 10.1016/j.pep.2014.09.019 |
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2014 Journal Article PhosphoPICK: modelling cellular context to map kinase-substrate phosphorylation eventsPatrick, Ralph, Lê Cao, Kim-Anh, Kobe, Bostjan and Bodén, Mikael (2014). PhosphoPICK: modelling cellular context to map kinase-substrate phosphorylation events. Bioinformatics, 31 (3), 382-389. doi: 10.1093/bioinformatics/btu663 |
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2014 Journal Article Factors influencing nucleo-cytoplasmic trafficking: which matter? Response to Alvisi & Jans' comment on Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insightsRóna, Gergely, Borsos, Máté, Kobe, Bostjan and Vértessy, Beáta G. (2014). Factors influencing nucleo-cytoplasmic trafficking: which matter? Response to Alvisi & Jans' comment on Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallographica. Section D: Biological Crystallography, 70 (10), 2777-2778. doi: 10.1107/S1399004714020501 |
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2014 Journal Article The nuclear immune receptor RPS4 is required for RRS1SLH1-dependent constitutive defense activation in Arabidopsis thaliana.Sohn, Kee Hoon, Segonzac, Cecile, Rallapalli, Ghanasyam, Sarris, Panagiotis F., Woo, Joo Yong, Williams, Simon J., Newman, Toby E., Paek, Kyung Hee, Kobe, Bostjan and Jones, Jonathan D. G. (2014). The nuclear immune receptor RPS4 is required for RRS1SLH1-dependent constitutive defense activation in Arabidopsis thaliana.. PLoS Genetics, 10 (10), e1004655. doi: 10.1371/journal.pgen.1004655 |
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2014 Journal Article The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4Verstak, Brett, Stack, Julianne, Ve, Thomas, Mangan, Matthew, Hjerrild, Kathryn, Jeon, Jannah, Stahl, Rainer, Latz, Eicke, Gay, Nick, Kobe, Bostjan, Bowie, Andrew G. and Mansell, Ashley (2014). The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4. Journal of Leukocyte Biology, 96 (3), 427-436. doi: 10.1189/jlb.2A0913-487R |
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2014 Conference Publication Importin alpha and nonclassical nuclear localization signalChang, Chiung-Wen, Couñago, Rafael, Williams, Simon, Bodén, Mikael and Kobe, Boštjan (2014). Importin alpha and nonclassical nuclear localization signal. XXIII IUCr Congress, Montreal, Canada, 5-12 August 2014. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s205327331408365x |
