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2013

Journal Article

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

Chen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013). The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 (5), 774-784. doi: 10.1107/S0907444913001558

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

2013

Journal Article

DLocalMotif: a discriminative approach for discovering local motifs in protein sequences

Mehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2013). DLocalMotif: a discriminative approach for discovering local motifs in protein sequences. Bioinformatics, 29 (1), 39-46. doi: 10.1093/bioinformatics/bts654

DLocalMotif: a discriminative approach for discovering local motifs in protein sequences

2013

Journal Article

The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site in plant nuclear import factor importin-α

Chang, Chiung-Wen, Counago, Rafael Miguez, Williams, Simon J., Boden, Mikael and Kobe, Bostjan (2013). The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site in plant nuclear import factor importin-α. Plant Signaling and Behavior, 8 (10), e25976.1-e25976.6. doi: 10.4161/psb.25976

The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site in plant nuclear import factor importin-α

2013

Book Chapter

Protein phosphorylation

Ellis, Jonathan J. and Kobe, Boštjan (2013). Protein phosphorylation. Encyclopedia of biophysics. (pp. 2037-2040) edited by Gordon C. K. Roberts. Berlin, Germany: Springer-Verlag. doi: 10.1007/978-3-642-16712-6_184

Protein phosphorylation

2012

Journal Article

Crystal structure of rice importin-alpha and structural basis of its interaction with plant-specific nuclear localization signals

Chang, Chiung-Wen, Counago, Rafael Lemos Miguez, Williams, Simon J., Boden, Mikael and Kobe, Bostjan (2012). Crystal structure of rice importin-alpha and structural basis of its interaction with plant-specific nuclear localization signals. Plant Cell, 24 (12), 5074-5088. doi: 10.1105/tpc.112.104422

Crystal structure of rice importin-alpha and structural basis of its interaction with plant-specific nuclear localization signals

2012

Journal Article

Intramolecular interaction influences binding of the flax L5 and L6 resistance proteins to their AvrL567 ligands

Ravensdale, Michael, Bernoux, Maud, Ve, Thomas, Kobe, Bostjan, Thrall, Peter H., Ellis, Jeffrey G. and Dodds, Peter N. (2012). Intramolecular interaction influences binding of the flax L5 and L6 resistance proteins to their AvrL567 ligands. PloS Pathogens, 8 (11) e1003004, e1003004. doi: 10.1371/journal.ppat.1003004

Intramolecular interaction influences binding of the flax L5 and L6 resistance proteins to their AvrL567 ligands

2012

Journal Article

De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans

Morrow, Carl A., Valkov, Eugene, Stamp, Anna, Chow, Eve W. L., Lee, I. Russel, Wronski, Ania, Williams, Simon J., Hill, Justine M., Djordjevic, Julianne T., Kappler, Ulrke, Kobe, Bostjan and Fraser, James A. (2012). De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans. PLoS Pathogens, 8 (10) e1002957, e1002957. doi: 10.1371/journal.ppat.1002957

De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans

2012

Journal Article

Wzy-dependent bacterial capsules as potential drug targets

Ericsson, Daniel J., Standish, Alistair, Kobe, Bostjan and Morona, Renata (2012). Wzy-dependent bacterial capsules as potential drug targets. Current Drug Targets, 13 (11), 1421-1431. doi: 10.2174/138945012803530279

Wzy-dependent bacterial capsules as potential drug targets

2012

Journal Article

Prokaryotic substrate-binding proteins as targets for antimicrobial therapies

Counago, Rafael M., McDevitt, Christopher A., Ween, Miranda P. and Kobe, Bostjan (2012). Prokaryotic substrate-binding proteins as targets for antimicrobial therapies. Current Drug Targets, 13 (11), 1400-1410. doi: 10.2174/138945012803530170

Prokaryotic substrate-binding proteins as targets for antimicrobial therapies

2012

Journal Article

Adaptors in toll-like receptor signaling and their potential as therapeutic targets

Ve, Thomas, Gay, Nicholas J., Mansell, Ashley, Kobe, Bostjan and Kellie, Stuart (2012). Adaptors in toll-like receptor signaling and their potential as therapeutic targets. Current Drug Targets, 13 (11), 1360-1374. doi: 10.2174/138945012803530260

Adaptors in toll-like receptor signaling and their potential as therapeutic targets

2012

Journal Article

Computational modelling of linear motif-mediated protein interactions

Kobe, Bostjan and Boden, Mikael (2012). Computational modelling of linear motif-mediated protein interactions. Current Topics in Medicinal Chemistry, 12 (14), 1553-1561. doi: 10.2174/156802612802652439

Computational modelling of linear motif-mediated protein interactions

2012

Journal Article

Structural basis of nuclear import of flap endonuclease 1 (FEN1)

de Barros, Andrea C., Takeda, Agnes A. S., Chang, Chiung-Wen, Kobe, Bostjan and Fontes, Marcos R. M. (2012). Structural basis of nuclear import of flap endonuclease 1 (FEN1). Acta Crystallographica Section D: Biological Crystallography, 68 (7), 743-750. doi: 10.1107/S0907444912010281

Structural basis of nuclear import of flap endonuclease 1 (FEN1)

2012

Journal Article

Mapping the stabilome: a novel computational method for classifying metabolic protein stability

Patrick, Ralph, Cao, Kim-Anh L., Davis, Melissa, Kobe, Bostjan and Bodén, Mikael (2012). Mapping the stabilome: a novel computational method for classifying metabolic protein stability. BMC Systems Biology, 6 (1) 60, 60.1-60.15. doi: 10.1186/1752-0509-6-60

Mapping the stabilome: a novel computational method for classifying metabolic protein stability

2012

Journal Article

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

Chen, Kai-En, Richards, Ayanthi A., Arrifin, Juliana K., Ross, Ian L., Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer L. (2012). The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallographica Section D: Biological Crystallography, 68 (6), 637-648. doi: 10.1107/S0907444912006592

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

2012

Journal Article

Structural basis of high-affinity nuclear localization signal interactions with importin-alpha

Marfori, Mary, Lonhienne, Thierry G., Forwood, Jade K. and Kobe, Bostjan (2012). Structural basis of high-affinity nuclear localization signal interactions with importin-alpha. Traffic, 13 (4), 532-548. doi: 10.1111/j.1600-0854.2012.01329.x

Structural basis of high-affinity nuclear localization signal interactions with importin-alpha

2012

Journal Article

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

Stark, Mitchell S., Woods, Susan L., Gartside, Michael G., Bonazzi, Vanessa F., Dutton-Regester, Ken, Aoude, Lauren G., Chow, Donald, Sereduk, Chris, Niemi, Natalie M., Tang, Nanyun, Ellis, Jonathan J., Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M., Pollak, Thomas, Youngkin, David, Brooks, Bradford R., Lanagan, Catherine, Schmidt, Christopher W., Kobe, Bostjan, MacKeigan, Jeffrey P., Yin, Hongwei, Brown, Kevin M., Gibbs, Richard, Trent, Jeffrey and Hayward, Nicholas K. (2012). Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nature Genetics, 44 (2), 165-169. doi: 10.1038/ng.1041

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

2012

Journal Article

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

Henningham, Anna, Chiarot, Emiliano, Gillen, Christine M., Cole, Jason N., Rohde, Manfred, Fulde, Marcus, Ramachandran, Vidiya, Cork, Amanda J., Hartas, Jon, Magor, Graham, Djordjevic, Steven P., Cordwell, Stuart J., Kobe, Bostjan, Sriprakash, Kabada S., Nizet, Victor, Chhatwal, G. S., Margarit, Immaculada Y. R., Batzloff, Michael R. and Walker, Mark J. (2012). Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine, 90 (10), 1197-1207. doi: 10.1007/s00109-012-0897-9

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

2012

Journal Article

Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding

Watterson, Daniel, Kobe, Bostjan and Young, Paul R. (2012). Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding. Journal of General Virology, 93 (1), 72-82. doi: 10.1099/vir.0.037317-0

Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding

2011

Journal Article

Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM

Ve, Thomas, Williams, Simon J., Stamp, Anna, Valkov, Eugene, Dodds, Peter N., Anderson, Peter A. and Kobe, Bostjan (2011). Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 67 (12), 1603-1607. doi: 10.1107/S1744309111037675

Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM

2011

Journal Article

A molecular mechanism for bacterial susceptibility to zinc

McDevitt, Christopher A., Ogunniyi, Abiodun D., Valkov, Eugene, Lawrence, Michael C., Kobe, Bostjan, McEwan, Alastair G. and Paton, James C. (2011). A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7 (11) e1002357, e1002357.1-e1002357.9. doi: 10.1371/journal.ppat.1002357

A molecular mechanism for bacterial susceptibility to zinc