Dr Lucia Zacchi
Dr

Lucia Zacchi

Email: 

Background

I am a microbiologist, molecular cellular biologist, and genetic engineer with expertise in antibody discovery and characterization, yeast and mammalian cell line development, and mass spectrometry proteomics (with a focus on post-translational modifications).

I graduated from Universidad Nacional de Río Cuarto, Argentina. I then obtained a Fulbright Scholarship to pursue my Ph.D. in Microbiology, Immunology, and Cancer Biology at the University of Minnesota, USA. For my dissertation I studied genetic and epigenetic mechanisms of phenotypic variation in the pathogenic yeast Candida albicans. I did post-doctoral work in the laboratories of Dr. Jeffrey Brodsky (University of Pittsburgh, USA), Dr. Julio Caramelo (Fundación Instituto Leloir, Argentina), Dr. Benjamin L. Schulz (SCMB, UQ), and the ARC Training Centre for Biopharmaceutical Innovation (AIBN, UQ). I have received Fellowships from the Dystonia Medical Research Foundation, CONICET-Argentina, Endeavour-Australia, and The University of Queensland.

Research Area and Impact

In my team, we believe we can help prevent, diagnose, treat, and cure diseases; and we work every day to design new antibody-based therapies and to develop novel approaches to discovering antibodies against difficult targets.

Availability

Dr Lucia Zacchi is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, University of Minnesota

Search Professor Lucia Zacchi’s works on UQ eSpace

31 works between 2007 and 2024
All (31) Journal Article (28) Book Chapter (2) Conference Publication (1)

21 - 31 of 31 works

2017

Journal Article

N-glycosylation triggers a dual selection pressure in eukaryotic secretory proteins

Medus, Maximo L., Gomez, Gabriela E., Zacchi, Lucia F., Couto, Paula M., Labriola, Carlos A., Labanda, Maria S., Bielsa, Rodrigo Corti, Clérico, Eugenia M., Schulz, Benjamin L. and Caramelo, Julio J. (2017). N-glycosylation triggers a dual selection pressure in eukaryotic secretory proteins. Scientific Reports, 7 (1) 8788, 8788. doi: 10.1038/s41598-017-09173-6

N-glycosylation triggers a dual selection pressure in eukaryotic secretory proteins

2016

Book Chapter

Endoplasmic reticulum-associated degradation and protein quality control

Zacchi, L.F., Caramelo, J.J., McCracken, A.A. and Brodsky, J.L. (2016). Endoplasmic reticulum-associated degradation and protein quality control. Encyclopedia of cell biology. (pp. 596-611) edited by Ralph A. Bradshaw and Philip D. Stahl. Waltham, MA, United States: Academic Press. doi: 10.1016/B978-0-12-394447-4.10072-0

Endoplasmic reticulum-associated degradation and protein quality control

2014

Journal Article

Erratum to: Biocontrol and PGPR features in native strains isolated from saline soils of Argentina

Principe, Analia, Alvarez, Florencia, Castro, Marina G., Zacchi, Lucia F., Fischer, Sonia E., Mori, Gladys B. and Jofre, Edgardo (2014). Erratum to: Biocontrol and PGPR features in native strains isolated from saline soils of Argentina. Current Microbiology, 69 (3), 404-404. doi: 10.1007/s00284-014-0601-0

Erratum to: Biocontrol and PGPR features in native strains isolated from saline soils of Argentina

2014

Journal Article

The BiP molecular chaperone plays multiple roles during the biogenesis of TorsinA, an AAA+ ATPase associated with the neurological disease Early-Onset Torsion Dystonia

Zacchi, Lucía F., Wu, Hui-Chuan, Bell, Samantha L., Millen, Linda, Paton, Adrienne W., Paton, James C., Thomas, Philip J., Zolkiewski, Michal and Brodsky, Jeffrey L. (2014). The BiP molecular chaperone plays multiple roles during the biogenesis of TorsinA, an AAA+ ATPase associated with the neurological disease Early-Onset Torsion Dystonia. Journal of Biological Chemistry, 289 (18), 12727-12747. doi: 10.1074/jbc.M113.529123

The BiP molecular chaperone plays multiple roles during the biogenesis of TorsinA, an AAA+ ATPase associated with the neurological disease Early-Onset Torsion Dystonia

2014

Journal Article

Intracellular Complexes of the Early-Onset Torsion Dystonia-Associated AAA+ ATPase TorsinA

Li, Hui, Wu, Hui-Chuan, Liu, Zhonghua, Zacchi, Lucia F., Brodsky, Jeffrey L. and Zolkiewski, Michal (2014). Intracellular Complexes of the Early-Onset Torsion Dystonia-Associated AAA+ ATPase TorsinA. SpringerPlus, 3 (1) 743, 743.1-743.5. doi: 10.1186/2193-1801-3-743

Intracellular Complexes of the Early-Onset Torsion Dystonia-Associated AAA+ ATPase TorsinA

2013

Journal Article

Shuttle vectors for facile cloning through gap repair and integration into a neutral locus in Candida albicans

Gerami-Nejad, Maryam, Zacchi, Lucia F., McClellan, Mark, Matter, Kathleen and Berman, Judith (2013). Shuttle vectors for facile cloning through gap repair and integration into a neutral locus in Candida albicans. Microbiology, 159 (Part 3), 565-579. doi: 10.1099/mic.0.064097-0

Shuttle vectors for facile cloning through gap repair and integration into a neutral locus in Candida albicans

2012

Conference Publication

The ER chaperones BiP and Jem1/Scj1 are genetic modifiers of TorsinA, the AAA plus ATPase associated with the neurological disease primary torsion dystonia

Zacchi, Lucia Florencia, Wu, Hui-Chuan, Niemeyer, Katie, Bell, Samantha, Zolkiewski, Michal and Brodsky, Jeffrey (2012). The ER chaperones BiP and Jem1/Scj1 are genetic modifiers of TorsinA, the AAA plus ATPase associated with the neurological disease primary torsion dystonia. Experimental Biology Meeting, San Diego, CA, United States, 21-25 April 2012. Hoboken, NJ, United States: John Wiley & Sons.

The ER chaperones BiP and Jem1/Scj1 are genetic modifiers of TorsinA, the AAA plus ATPase associated with the neurological disease primary torsion dystonia

2010

Journal Article

HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis

Zacchi, Lucia F., Schulz, Wade L. and Davis, Dana A. (2010). HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis. PLoS One, 5 (8), e12171.1-e12171.7. doi: 10.1371/journal.pone.0012171

HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis

2010

Journal Article

Mds3 regulates morphogenesis in Candida albicans through the TOR pathway

Zacchi, Lucia F., Gomez-Raja, Jonathan and Davis, Dana A. (2010). Mds3 regulates morphogenesis in Candida albicans through the TOR pathway. Molecular and Cellular Biology, 30 (14), 3695-3710. doi: 10.1128/MCB.01540-09

Mds3 regulates morphogenesis in Candida albicans through the TOR pathway

2010

Journal Article

Low dosage of histone H4 leads to growth defects and morphological changes in Candida albicans

Zacchi, Lucia F., Selmecki, Anna M., Berman, Judith and Davis, Dana A. (2010). Low dosage of histone H4 leads to growth defects and morphological changes in Candida albicans. PLoS One, 5 (5), e10629.1-e10629.12. doi: 10.1371/journal.pone.0010629

Low dosage of histone H4 leads to growth defects and morphological changes in Candida albicans

2007

Journal Article

Biocontrol and PGPR features in native strains isolated from saline soils of Argentina

Principe, Analia, Alvarez, Florencia, Castro, Marina G., Zacchi, Lucia, Fischer, Sonia E., Mori, Gladys B. and Jofre, Edgardo (2007). Biocontrol and PGPR features in native strains isolated from saline soils of Argentina. Current Microbiology, 55 (4), 314-322. doi: 10.1007/s00284-006-0654-9

Biocontrol and PGPR features in native strains isolated from saline soils of Argentina

Availability

Dr Lucia Zacchi is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Dr Lucia Zacchi directly for media enquiries about:

  • Dystonia
  • Glycobiology
  • Proteomics
  • Yeast genetic engineering

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