
Overview
Availability
- Dr Simon de Veer is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Queensland University of Technology
Works
Search Professor Simon de Veer’s works on UQ eSpace
2024
Journal Article
Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligation
de Veer, Simon J., Craik, David J. and Rehm, Fabian B. H. (2024). Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligation. Journal of the American Chemical Society, 147 (1), 557-565. doi: 10.1021/jacs.4c11964
2024
Journal Article
Display technologies for expanding the pharmaceutical applications of cyclotides
Xie, Jing, Kan, Meng‐Wei, de Veer, Simon J., Wang, Conan and Craik, David J. (2024). Display technologies for expanding the pharmaceutical applications of cyclotides. Israel Journal of Chemistry, 64 (8-9) e202400010. doi: 10.1002/ijch.202400010
2024
Journal Article
Enhancing the intrinsic antiplasmodial activity and improving the stability and selectivity of a tunable peptide scaffold derived from human platelet factor 4
Lawrence, Nicole, Handley, Thomas N. G., de Veer, Simon J., Harding, Maxim D., Andraszek, Alicja, Hall, Lachlan, Raven, Karoline D., Duffy, Sandra, Avery, Vicky M., Craik, David J., Malins, Lara R. and McMorran, Brendan J. (2024). Enhancing the intrinsic antiplasmodial activity and improving the stability and selectivity of a tunable peptide scaffold derived from human platelet factor 4. ACS Infectious Diseases, 10 (8), 2899-2912. doi: 10.1021/acsinfecdis.4c00276
2024
Journal Article
Nucleation of a key beta-turn promotes cyclotide oxidative folding
Tian, Sixin, de Veer, Simon J., Durek, Thomas, Wang, Conan K. and Craik, David J. (2024). Nucleation of a key beta-turn promotes cyclotide oxidative folding. Journal of Biological Chemistry, 300 (4) 107125, 107125. doi: 10.1016/j.jbc.2024.107125
2024
Journal Article
Tertiary amide bond formation by an engineered asparaginyl ligase
de Veer, Simon J., Zhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Tertiary amide bond formation by an engineered asparaginyl ligase. Chemical Science, 15 (14) 06352, 5248-5255. doi: 10.1039/d3sc06352f
2022
Journal Article
Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIa
Tian, Sixin, Durek, Thomas, Wang, Conan K., Zdenek, Christina N., Fry, Bryan G., Craik, David J. and de Veer, Simon J. (2022). Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIa. Journal of Medicinal Chemistry, 65 (23), 15698-15709. doi: 10.1021/acs.jmedchem.2c01080
2022
Journal Article
Cystine knot peptides with tuneable activity and mechanism
Li, Choi Yi, Rehm, Fabian B. H., Yap, Kuok, Zdenek, Christina N., Harding, Maxim D., Fry, Bryan G., Durek, Thomas, Craik, David J. and Veer, Simon J. (2022). Cystine knot peptides with tuneable activity and mechanism. Angewandte Chemie, 61 (19) e202200951, e202200951. doi: 10.1002/ange.202200951
2022
Journal Article
Enzymatic C‐to‐C Protein Ligation
Rehm, Fabian B. H., Tyler, Tristan J., Veer, Simon J., Craik, David J. and Durek, Thomas (2022). Enzymatic C‐to‐C Protein Ligation. Angewandte Chemie International Edition, 134 (11) e202116672, e202116672. doi: 10.1002/anie.202116672
2022
Journal Article
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
Wu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9
2021
Journal Article
Enzymatic C-terminal protein engineering with amines
Rehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, de Veer, Simon J., Craik, David J. and Durek, Thomas (2021). Enzymatic C-terminal protein engineering with amines. Journal of the American Chemical Society, 143 (46) jacs.1c08976, 19498-19504. doi: 10.1021/jacs.1c08976
2021
Journal Article
An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffold
Liu, Wenyu, de Veer, Simon J., Huang, Yen-Hua, Sengoku, Toru, Okada, Chikako, Ogata, Kazuhiro, Zdenek, Christina N., Fry, Bryan G., Swedberg, Joakim E., Passioura, Toby, Craik, David J. and Suga, Hiroaki (2021). An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffold. Journal of the American Chemical Society, 143 (44) jacs.1c07574, 18481-18489. doi: 10.1021/jacs.1c07574
2021
Journal Article
Melanocortin 1 receptor agonists based on a bivalent, bicyclic peptide framework
Durek, Thomas, Kaas, Quentin, White, Andrew M., Weidmann, Joachim, Fuaad, Abdullah Ahmad, Cheneval, Olivier, Schroeder, Christina I., de Veer, Simon J., Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Plowright, Alleyn T. and Craik, David J. (2021). Melanocortin 1 receptor agonists based on a bivalent, bicyclic peptide framework. Journal of Medicinal Chemistry, 64 (14) acs.jmedchem.1c00095, 9906-9915. doi: 10.1021/acs.jmedchem.1c00095
2021
Journal Article
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases
Yap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2021). Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature Protocols, 16 (3), 1-23. doi: 10.1038/s41596-020-00483-0
2020
Journal Article
Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie
Veer, Simon J., White, Andrew M. and Craik, David J. (2020). Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie. Angewandte Chemie, 133 (15), 8128-8151. doi: 10.1002/ange.202006919
2020
Journal Article
Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology
de Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition), 59 (15), 2-24. doi: 10.1002/anie.202006919
2020
Journal Article
An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides
Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h
2020
Journal Article
Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713
2020
Journal Article
Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713
2020
Journal Article
Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435
2020
Journal Article
Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors
Li, Choi Yi, Yap, Kuok, Swedberg, Joakim E., Craik, David J. and de Veer, Simon J. (2020). Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b01811, 816-826. doi: 10.1021/acs.jmedchem.9b01811
Funding
Past funding
Supervision
Availability
- Dr Simon de Veer is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of novel peptide based drug leads for chronic myeloid leukaemia
Associate Advisor
Other advisors: Dr Thomas Durek, Professor David Craik
Completed supervision
-
2023
Doctor Philosophy
Structural Modifications to Optimise the Oxidative Folding and Activity of Cyclotides
Associate Advisor
Other advisors: Dr Conan Wang, Professor David Craik
-
2021
Doctor Philosophy
Engineering serine protease inhibitors using cyclic peptides and sequence-defined libraries
Associate Advisor
Other advisors: Professor David Craik
Media
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