Overview
Background
Peter Csurhes is an immunologist with a strong research track record in multiple sclerosis (MS) research within UQ that has spanned 30 years.
Together with Emeritus Professor Michael Pender, Peter’s work in a number of preclinical research studies into the role that immunity to Epstein-Barr virus (EBV) plays in MS disease pathogenesis has translated to clinical trials testing of potentially ground-breaking new T cell immunotherapeutic treatments for progressive MS. Collaborative links between QIMR Berghofer, Royal Brisbane and Women’s Hospital and commercial partners have been established and clinical trials are ongoing.
After the retirement of Professor Pender, Peter has taken on a chief investigator role, and in 2023 gained successful NHMRC MRFF funding to continue research into the biology of the Epstein-Barr virus and the role it plays in the multiple sclerosis disease process.
Peter has also been involved in studying the role of reactivity to autoantigens in MS and in diseases of the peripheral nervous system including Guillain-Barre syndrome and CIDP.
For several years he worked on the immunology of potential malaria vaccine candidates and also worked part-time for 18 months on research into EBV-related cancers within the QIMR-Berghofer Medical Research Institute.
Availability
- Mr Peter Csurhes is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
Works
Search Professor Peter Csurhes’s works on UQ eSpace
2011
Journal Article
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Ritchie, Matthew E., Liu, Ruijie, Carvalho, Benilton S., The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Irizarry, Rafael A., Brown, Matthew A., Csurhes, Peter A., Danoy, Patrick, Greer, Judith M., Hadler, Johanna, Pryce, Karena and Pender, Michael P. (2011). Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips. BMC Bioinformatics, 12 (4) 68, 68.1-68.12. doi: 10.1186/1471-2105-12-68
2010
Journal Article
Strains of Epstein-Barr virus infecting multiple sclerosis patients
Brennan, R. M., Burrows, J. M., Bell, M. J., Bromham, L., Csurhes, P. A., Lenarczyk, A., Sverndal, J., Klintenstedt, J., Pender, M. P. and Burrows, S. R. (2010). Strains of Epstein-Barr virus infecting multiple sclerosis patients. Multiple Sclerosis, 16 (6), 643-651. doi: 10.1177/1352458510364537
2010
Journal Article
Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis
Szvetko, Attila, Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter, Greer, Judith, Pender, Michael and Griffiths, Lyn (2010). Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis. Neurological Research [electronic resource], 32 (4), 438-441. doi: 10.1179/174313209X405155
2010
Journal Article
T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1
McCombe, P. A. and Csurhes, P. A. (2010). T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1. Journal of Clinical Neuroscience, 17 (4), 537-538. doi: 10.1016/j.jocn.2009.07.096
2010
Journal Article
Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies
Bahlo, Melanie, Stankovich, Jim, Danoy, Patrick, Hickey, Peter F., Taylor, Bruce V., Browning, Sharon R., The Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Brown, Matthew A., Rubio, Justin P., Csurhes, Peter A., Greer, Judith, Pender, Michael P. and Pryce, Karena (2010). Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiology, Biomarkers and Prevention, 19 (3), 794-798. doi: 10.1158/1055-9965.EPI-09-0812
2009
Journal Article
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Bahlo, Melanie, Booth, David R., Broadley, Simon A., Brown, Matthew A., Foote, Simon J., Griffiths, Lyn R., Kilpatrick, Trevour J., Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M., Rubio, Justin P., Scott, Rodney J., Stankovich, Jim, Stewart, Graeme J., Taylor, Bruce V., Wiley, James, Clarke, Glynnis, Cox, Mathew B., Csurhes, Peter A., Danoy, Patrick, Drysdale, Karen, Field, Judith, Foote, Simon J., Greer, Judith M., Griffiths, Lyn R, Hadler, Johanna, McMorran, Brendan J., Jensen, Cathy J., Johnson, Laura J. ... Willoughby, Ernest (2009). Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics, 41 (7), 824-828. doi: 10.1038/ng.396
2009
Journal Article
Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population
Mackenzie, Jason, Tajouri, Lotti, Szvetko, Attila, Weth, Verena, Moreau, Julie, Greer, Judith M., Csurhes, Peter A., Pender, Michael P. and Griffiths, Lyn R. (2009). Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population. Journal of the Neurological Sciences, 280 (1-2), 62-64. doi: 10.1016/j.jns.2009.01.026
2009
Journal Article
An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population
Szvetko, Attila L., Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter A., Greer, Judith M., Pender, Michael P. and Griffiths, Lyn R. (2009). An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population. Brain Research, 1255, 148-152. doi: 10.1016/j.brainres.2008.12.017
2009
Journal Article
Decreased T cell reactivity to Epstein–Barr virus infected lymphoblastoid cell lines in multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Lenarczyk, Aleksandra, Pfluger, Casey M. M. and Burrows, S. R. (2009). Decreased T cell reactivity to Epstein–Barr virus infected lymphoblastoid cell lines in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 80 (5), 498-505. doi: 10.1136/jnnp.2008.161018
2008
Journal Article
Correlation of blood T cell and antibody reactivity to myelin proteins with HLA type and lesion localization in multiple sclerosis
Greer, Judith M., Csurhes, Peter A., Muller, Diane M. and Pender, Michael P. (2008). Correlation of blood T cell and antibody reactivity to myelin proteins with HLA type and lesion localization in multiple sclerosis. Journal of Immunology, 180 (9), 6402-6410. doi: 10.4049/jimmunol.180.9.6402
2008
Conference Publication
Role of autoreactivity against myelin proteolipid protein in multiple sclerosis
Greer, Judith, Csurhes, Peter, Muller, Diane and Pender, Michael (2008). Role of autoreactivity against myelin proteolipid protein in multiple sclerosis. ISNI 2008: 9th International Congress of Neuroimmunology, Fort Worth, TX, U.S.A., October 26-30, 2008. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jneuroim.2008.08.001
2008
Conference Publication
Infection with specific strains of Epstein-Barr virus are a risk factor for multiple sclerosis
Brennan, Rebekah M., Burrows, Jacqueline M., Bell, Melissa J., Lenarczyk, Aleksandra, Csurhes, Peter A., Pender, Michael. and Burrows, Scott R. (2008). Infection with specific strains of Epstein-Barr virus are a risk factor for multiple sclerosis. Joint World Congress on Treatment and Research in Multiple Sclerosis: 13th Annnual Meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis / 24th Congress of the European Committee for Treatment and Research in Multiple Sclerosis / 5th Congress of the Latin American Committee for Treatment and Research in Multiple Sclerosis, Montréal, QC, Canada, 17-20 September 2008. London, U.K.: Sage Publications. doi: 10.1177/1352458508096399
2007
Journal Article
Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflammatory demyelinating neuropathy
Inglis, H. R., Csurhes, P. A. and McCombe, P. A. (2007). Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflammatory demyelinating neuropathy. Journal of Neurology, Neurosurgery & Psychiatry, 78 (4), 419-422. doi: 10.1136/jnnp.2006.106617
2007
Journal Article
Allelic Variation Investigation of the Estrogen Receptor Within an Australian Multiple Sclerosis Population
Tajouri, Lotti, Fernandez, Francesca, Tajouri, Sophie, Detriche, Geraldine, Szvetko, Attila, Colson, Natalie, Csurhes, Peter, Pender, M. P. and Griffiths, Lyn R. (2007). Allelic Variation Investigation of the Estrogen Receptor Within an Australian Multiple Sclerosis Population. Journal of the Neurological Sciences, 252 (1), 9-12. doi: 10.1016/j.jns.2006.09.018
2007
Journal Article
No Association Between MTHFR A1298C and MTRR A66G Polymorphisms, and MS in an Australian Cohort
Szvetko, A. L., Fowdar, J., Nelson, J., Colson, N., Tajouri, L., Csurhes, P. A., Pender, M. P. and Griffiths, L. R. (2007). No Association Between MTHFR A1298C and MTRR A66G Polymorphisms, and MS in an Australian Cohort. Journal of the Neurological Sciences, 252 (1), 49-52. doi: 10.1016/j.jns.2006.10.006
2006
Journal Article
Studies of HLA associations in male and female patients with Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
McCombe, Pamela A., Csurhes, Peter A. and Greer, Judith M. (2006). Studies of HLA associations in male and female patients with Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Journal of Neuroimmunology, 180 (1-2), 172-177. doi: 10.1016/j.jneuroim.2006.07.017
2006
Journal Article
Genetic Investigation of Methylenetetrahydrofolate Reductase (MTHFR) and Catechol-O-Methyl Transferase (COMT) in Multiple Sclerosis
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., Haupt, Larisa M., Csurhes, Peter, Pender, Michael P. and Griffiths, Lyn R. (2006). Genetic Investigation of Methylenetetrahydrofolate Reductase (MTHFR) and Catechol-O-Methyl Transferase (COMT) in Multiple Sclerosis. Brain Research Bulletin, 69 (3), 327-331. doi: 10.1016/j.brainresbull.2006.01.005
2006
Conference Publication
T-cell reactivity to myelin proteolipid protein drives the development of brainstem and cerebellar lesions in multiple sclerosis
Pender, M. P., Csurhes, P. A. and Greer, J. M. (2006). T-cell reactivity to myelin proteolipid protein drives the development of brainstem and cerebellar lesions in multiple sclerosis. 8th International Conference on Neuroimmunology, Nagoya, Japan, 15-19 October 2006. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.jneuroim.2006.07.002
2005
Journal Article
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy
Csurhes, P. A., Sullivan, A-A., Green, K., Pender, M. P. and McCombe, P. A. (2005). T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. Journal of Neurology, Neurosurgery, and Psychiatry, 76 (10), 1431-1439. doi: 10.1136/jnnp.2004.052282
2005
Journal Article
Increased Circulating T Cell Reactivity to GM1 Ganglioside in Patients with Guillain-Barre Syndrome
Csurhes, Peter A., Sullivan, Alice-Ann, Green, Kerryn, Greer, Judith M., Pender, Michael P. and McCombe, Pamela A. (2005). Increased Circulating T Cell Reactivity to GM1 Ganglioside in Patients with Guillain-Barre Syndrome. Journal of Clinical Neuroscience, 12 (4), 409-415. doi: 10.1016/j.jocn.2004.04.006
Funding
Current funding
Media
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