Overview
Background
Peter Csurhes is an immunologist with a strong research track record in multiple sclerosis (MS) research within UQ that has spanned 30 years.
Together with Emeritus Professor Michael Pender, Peter’s work in a number of preclinical research studies into the role that immunity to Epstein-Barr virus (EBV) plays in MS disease pathogenesis has translated to clinical trials testing of potentially ground-breaking new T cell immunotherapeutic treatments for progressive MS. Collaborative links between QIMR Berghofer, Royal Brisbane and Women’s Hospital and commercial partners have been established and clinical trials are ongoing.
After the retirement of Professor Pender, Peter has taken on a chief investigator role, and in 2023 gained successful NHMRC MRFF funding to continue research into the biology of the Epstein-Barr virus and the role it plays in the multiple sclerosis disease process.
Peter has also been involved in studying the role of reactivity to autoantigens in MS and in diseases of the peripheral nervous system including Guillain-Barre syndrome and CIDP.
For several years he worked on the immunology of potential malaria vaccine candidates and also worked part-time for 18 months on research into EBV-related cancers within the QIMR-Berghofer Medical Research Institute.
Availability
- Mr Peter Csurhes is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
Works
Search Professor Peter Csurhes’s works on UQ eSpace
2005
Conference Publication
HLA-DR2 is associated with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in females, but not males
McCombe, P. A., Csurhes, P. A., Alizart, M. A. and Greer, J. M. (2005). HLA-DR2 is associated with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in females, but not males. 5th Annual Meeting of the Federation-of-Clinical-Immunology-Society, Boston, MA, U.S.A., 12-16 May 2005. Orlando, Florida: Academic Press.
2005
Journal Article
Variation in The Vitamin D Receptor Gene is Associated With Multiple Sclerosis in an Australian Population
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, Pender, Michael P. and Lea, Rod A. (2005). Variation in The Vitamin D Receptor Gene is Associated With Multiple Sclerosis in an Australian Population. Journal of Neurogenetics, 19 (1), 25-38. doi: 10.1080/01677060590949692
2004
Journal Article
Investigation Of An Inducible Nitric Oxide Synthase Gene (NOS2A) Polymorphism In A Multiple Sclerosis Population
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, Pender, Michael P. and Griffiths, Lyn R. (2004). Investigation Of An Inducible Nitric Oxide Synthase Gene (NOS2A) Polymorphism In A Multiple Sclerosis Population. Brain Research Bulletin, 64 (1), 9-13. doi: 10.1016/j.brainresbull.2004.04.019
2004
Journal Article
Effect Of Gender On T-Cell Proliferative Responses To Myelin Proteolipid Protein Antigens In Patients With Multiple Sclerosis And Controls
Greer, Judith M., Csurhes, Peter A., Pender, Michael P. and McCombe, Pamela A. (2004). Effect Of Gender On T-Cell Proliferative Responses To Myelin Proteolipid Protein Antigens In Patients With Multiple Sclerosis And Controls. Journal of Autoimmunity, 22 (4), 345-352. doi: 10.1016/j.jaut.2004.03.004
2004
Journal Article
Investigation of a Neuronal Nitric Oxide Synthase Gene (NOS1) Polymorphism in a Multiple Sclerosis Population
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., Pender, Michael P. and Griffiths, Lyn R. (2004). Investigation of a Neuronal Nitric Oxide Synthase Gene (NOS1) Polymorphism in a Multiple Sclerosis Population. Journal of the Neurological Sciences, 218 (1-2), 25-28. doi: 10.1016/j.jns.2003.10.006
2004
Conference Publication
Clinical and immunological findings in patients with concurrent MS and autoimmune thyroid disease
Greer, J. M., Tan, K. M., Wolfe, N. P., Csurhes, P. A. and Pender, M. P. (2004). Clinical and immunological findings in patients with concurrent MS and autoimmune thyroid disease. ACTRIMS 03, San Francisco, 19 October, 2003. United Kingdom: Arnold.
2003
Journal Article
Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Wolfe, Nigel P., Hooper, Kaye D., Good, Michael F., McCombe, Pamela A. and Greer, Judith M. (2003). Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis. Journal of Clinical Neuroscience, 10 (1), 63-66. doi: 10.1016/S0967-5868(02)00270-9
2003
Journal Article
Early pregnancy factor suppresses the infiltration of lymphocytes and macrophages in the spinal cord of rats during experimental autoimmune encephalomyelitis but has no effect on apoptosis
Athanasas-Platsis, S., Zhang, B., Hillyard, N. C., Cavanagh, A. C., Csurhes, P. A., Morton, H. and McCombe, P. A. (2003). Early pregnancy factor suppresses the infiltration of lymphocytes and macrophages in the spinal cord of rats during experimental autoimmune encephalomyelitis but has no effect on apoptosis. Journal of the Neurological Sciences, 214 (1-2), 27-36. doi: 10.1016/S0022-510X(03)00170-9
2002
Conference Publication
T cell responses to gangliosides in patients with inflammatory neuropathy
McCombe, P. A., Sullivan, A. A., Alizart, M. A., Csurhes, P. A., Greer, J. M. and Pender, M. P. (2002). T cell responses to gangliosides in patients with inflammatory neuropathy. Xth International Congress on Neuromuscular Diseases, Vancouver, Canada, 07-12 Jul 2002. Amsterda, The Netherlands: Elseiver. doi: 10.1016/S0022-510X(02)80069-7
2002
Conference Publication
Blood T-cell reactivity to gangliosides GM3 and GQ1b is increased in patients with primary progressive multiple sclerosis
Pender, M. P., Csurhes, P. A., Wolfe, N. P., Cameron, K. D., McCombe, P. A., Greer, J. M. and Good, M. F. (2002). Blood T-cell reactivity to gangliosides GM3 and GQ1b is increased in patients with primary progressive multiple sclerosis. 127th Annual Meeting of the American Neurological Association, New York City, NY, USA, October 12-16 2002. NEW YORK: WILEY-LISS.
2000
Journal Article
Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis than in Healthy Subjects
Pender, Michael P., Csurhes, Peter A., Greer, Judith M., Mowat, Paul D., Henderson, Robert D., Cameron, Kaye D., Purdie, David M., McCombe, Pamela A. and Good, Michael F. (2000). Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis than in Healthy Subjects. Journal of Immunology, 165 (9), 5322-5331. doi: 10.4049/jimmunol.165.9.5322
1999
Conference Publication
The role of PMP-22 as an autoantigen in GBS and CIDP
Sullivan, A., Csurhes, P. A., Alizart, M., Pender, M. P. and McCombe, P. A. (1999). The role of PMP-22 as an autoantigen in GBS and CIDP. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.
1999
Conference Publication
Fluctuations in the frequencies of circulating myelin-reactive T cells in healthy subjects and patients with multiple sclerosis
Pender, M. P., Csurhes, P. A., Greer, J. M., Mowat, P. D., Henderson, R. D., Cameron, K. D., McCombe, P. A. and Good, M. F. (1999). Fluctuations in the frequencies of circulating myelin-reactive T cells in healthy subjects and patients with multiple sclerosis. ECTRIMS/ACTRIMS'99, Basel, Switzerland, 15 - 18 Sept, 1999. Basingstoke, England: Stockton Press.
1998
Conference Publication
The frequency of circulating T cells reactive to PLP184-209 increases prior to MS relapse and development of new MR1 lesions
Cameron, K. D., Csurhes, P. A., Good, M. F., Greer, J. M., Henderson, R. D., McCombe, P. A., Mowat, P. D. and Pender, M. P. (1998). The frequency of circulating T cells reactive to PLP184-209 increases prior to MS relapse and development of new MR1 lesions. Fifth International Congress of the International Society of Neuroimmunology, Montreal, QC, Canada, 23-27 August 1998. doi: 10.1016/S0165-5728(98)91636-8
1997
Journal Article
Increased Immunoreactivity to Two Overlapping Peptides of Myelin Proteolipid Protein in Multiple Sclerosis
Greer, J. M., Csurhes, P. A., Cameron, K. D., McCombe, P. A., Good, M. F. and Pender, M. P. (1997). Increased Immunoreactivity to Two Overlapping Peptides of Myelin Proteolipid Protein in Multiple Sclerosis. Brain, 120 (8), 1447-1460. doi: 10.1093/brain/120.8.1447
1997
Journal Article
Corrigendum to "A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein" (J. Neuroimmunol. 70, 65-74)
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1997). Corrigendum to "A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein" (J. Neuroimmunol. 70, 65-74). Journal of Neuroimmunology, 73 (1-2), 213-213.
1997
Journal Article
Humoral immune responses of Solomon Islanders to the merozoite surface antigen 2 of Plasmodium falciparum show pronounced skewing towards antibodies of the immunoglobulin G3 subclass
Rzepczyk, Christine M., Hale, Kate, Woodroffe, Nick, Bobogare, Albino, Csurhes, Peter, Ishii, Akira and Ferrante, Antonio (1997). Humoral immune responses of Solomon Islanders to the merozoite surface antigen 2 of Plasmodium falciparum show pronounced skewing towards antibodies of the immunoglobulin G3 subclass. Infection and Immunity, 65 (3), 1098-1100.
1997
Journal Article
Erratum: A study of human T-cell lines generated from multiple sclerosis patients and controls by stimulation with peptides of myelin basic protein (J. Neuroimmunol. 70, 65-74 (1996))
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1997). Erratum: A study of human T-cell lines generated from multiple sclerosis patients and controls by stimulation with peptides of myelin basic protein (J. Neuroimmunol. 70, 65-74 (1996)). Journal of Neuroimmunology, 73 (1-2), 213-213. doi: 10.1016/S0165-5728(96)00222-6
1996
Journal Article
A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1996). A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein. Journal of Neuroimmunology, 70 (1), 65-74. doi: 10.1016/S0165-5728(96)00105-1
1996
Conference Publication
T-cell reactivity to peptides of proteolipid protein and myelin basic protein in multiple sclerosis
Pender, M. P., Greer, J. M., Csurhes, P. A., Cameron, K. D., McCombe, P. A. and Good, M. F. (1996). T-cell reactivity to peptides of proteolipid protein and myelin basic protein in multiple sclerosis. 121st Annual Meeting of the American Neurological Association, Miami, FL, U.S.A., 13-16 October 1996. BOSTON: LITTLE BROWN CO. doi: 10.1002/ana.410400326
Funding
Current funding
Media
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