Overview
Background
Professor Peter Sly is the Director, Children's Health and Environment Program. Professor Sly is a NHMRC Leadership Fellow (L3) and an emeritus paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. Professor Sly’s research aims to understand the mechanisms underlying chronic childhood lung diseases in order to improve clinical management and to delay or prevent their onset, with consequent reductions in adult lung diseases. A combination of basic science, longitudinal cohort studies and translation of research findings into clinical practice, including clinical trials, are included in three main areas: asthma, cystic fibrosis and children’s environmental health
Professor Sly is an advisor to the World Health Organisation Department of Public Health, Environmental and Social Determinants of Disease and currently serves on International Advisory Boards and committees, including: WHO network of Collaborating Centres in Children’s Environmental Health; Canadian Healthy Infant Longitudinal Development (CHILD) Study, Canada; the Infant Lung Health Study, Paarl, South Africa; and A SHARED Future: Achieving Strength, Health, and Autonomy, through Renewable Energy Development for the Future.
Availability
- Professor Peter Sly is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctoral Diploma of Medicine, University of Melbourne
- Doctoral Diploma of Science (Advanced), University of Western Australia
Research interests
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Asthma
Understanding mechanisms that underlie risks for developing asthma in susceptible children
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Cystic Fibrosis
Understanding the mechanisms underlying the development of lung disease early in life and why and how this progresses
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Impact of environmental exposures in early life
Improving methods of assessing environmental exposures during fetal development and in early postnatal life. Improving methods for assessing the effects of early life environmental exposures and understanding how these increase long-tern risk of chronic disease.
Works
Search Professor Peter Sly’s works on UQ eSpace
2024
Journal Article
Spatiotemporal hierarchical Bayesian analysis to identify factors associated with COVID-19 in suburban areas in Colombia
Cortes-Ramirez, J., Wilches-Vega, J.D., Caicedo-Velasquez, B., Paris-Pineda, O.M. and Sly, P.D. (2024). Spatiotemporal hierarchical Bayesian analysis to identify factors associated with COVID-19 in suburban areas in Colombia. Heliyon, 10 (9) e30182, 1-11. doi: 10.1016/j.heliyon.2024.e30182
2024
Book Chapter
Asthma, allergy, and the environment
Vilcins, Dwan and Sly, Peter D. (2024). Asthma, allergy, and the environment. Textbook of children's environmental health. (pp. 650-660) edited by Ruth A. Etzel and Philip J. Landrigan. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/oso/9780197662526.003.0048
2024
Journal Article
Blood lead, cadmium and hair mercury concentrations and association with soil, dust and occupational factors in e-waste recycling workers in Bangladesh
Parvez, Sarker Masud, Jahan, Farjana, Abedin, Jaynal, Rahman, Mahbubur, Hasan, Shaikh Sharif, Islam, Nafisa, Aich, Nirupam, Moniruzzaman, Mohammad, Islam, Zahir, Fujimura, Masatake, Raqib, Rubhana, Knibbs, Luke D. and Sly, Peter D. (2024). Blood lead, cadmium and hair mercury concentrations and association with soil, dust and occupational factors in e-waste recycling workers in Bangladesh. International Journal of Hygiene and Environmental Health, 257 114340, 114340. doi: 10.1016/j.ijheh.2024.114340
2024
Journal Article
Longitudinal tracking of intrabreath respiratory impedance in preschool children
Wong, Matthew D., Blake, Tamara L., Zahir, Syeda F., Suresh, Sadasivam, Hantos, Zoltán, Grimwood, Keith, Lambert, Stephen B., Ware, Robert S. and Sly, Peter D. (2024). Longitudinal tracking of intrabreath respiratory impedance in preschool children. Pediatric Pulmonology, 59 (7), 1885-1893. doi: 10.1002/ppul.26994
2024
Journal Article
Changes in urinary glutathione sulfonamide (GSA) levels between admission and discharge of patients with cystic fibrosis
Blake, Tamara L, Sly, Peter D, Andersen, Isabella, Wainwright, Claire E, Reid, David W, Bell, Scott C, Smith, Briana R, Kettle, Anthony J and Dickerhof, Nina (2024). Changes in urinary glutathione sulfonamide (GSA) levels between admission and discharge of patients with cystic fibrosis. Journal of Cystic Fibrosis. doi: 10.1016/j.jcf.2024.04.009
2024
Journal Article
Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort
McCready, Carlyle, Zar, Heather J, Chaya, Shaakira, Jacobs, Carvern, Workman, Lesley, Hantos, Zoltan, Hall, Graham L, Sly, Peter D, Nicol, Mark P, Stein, Dan J, Ullah, Anhar, Custovic, Adnan, Little, Francesca and Gray, Diane M (2024). Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort. The Lancet Child & Adolescent Health, 8 (6), 400-412. doi: 10.1016/s2352-4642(24)00072-5
2024
Journal Article
Indoor air pollution is associated with respiratory symptoms in children in urban Vietnam
Le, Hong H.T.C., Ngo, Hieu K.T., Hieu, Le Sy, Sly, Peter D., Phung, Dung, Le An, Pham, Vinh, Nguyen Nhu, Dang, Tran Ngoc, Thuong, Do Thi Hoai, Thanh, Huynh Ngoc and Thai, Phong K. (2024). Indoor air pollution is associated with respiratory symptoms in children in urban Vietnam. Science of the Total Environment, 917 170556, 170556. doi: 10.1016/j.scitotenv.2024.170556
2024
Journal Article
In utero smoking exposure induces changes to lung clearance index and modifies risk of wheeze in infants
De Queiroz Andrade, Ediane, Sena, Carla Rebeca Da Silva, de Gouveia Belinelo, Patricia, Robinson, Paul D., Blaxland, Anneliese, Sly, Peter D., Murphy, Vanessa E., Gibson, Peter G., Collison, Adam M. and Mattes, Joerg (2024). In utero smoking exposure induces changes to lung clearance index and modifies risk of wheeze in infants. Pediatric Pulmonology, 59 (6), 1686-1694. doi: 10.1002/ppul.26975
2024
Journal Article
Bronchiolitis hospital admission in infancy is associated with later preschool ventilation inhomogeneity
Sena, Carla Rebeca Da Silva, Morten, Matthew, Collison, Adam M., Shaar, Aida, Andrade, Ediane de Queiroz, Meredith, Joseph, Kepreotes, Elizabeth, Murphy, Vanessa E., Sly, Peter D., Whitehead, Bruce, Karmaus, Wilfried, Gibson, Peter G., Robinson, Paul D. and Mattes, Joerg (2024). Bronchiolitis hospital admission in infancy is associated with later preschool ventilation inhomogeneity. Pediatric Pulmonology, 59 (3), 632-641. doi: 10.1002/ppul.26793
2024
Journal Article
CFTR is required for zinc-mediated antibacterial defense in human macrophages
Das Gupta, Kaustav, Curson, James E. B., Tarique, Abdullah A., Kapetanovic, Ronan, Schembri, Mark A., Fantino, Emmanuelle, Sly, Peter D. and Sweet, Matthew J. (2024). CFTR is required for zinc-mediated antibacterial defense in human macrophages. Proceedings of the National Academy of Sciences, 121 (8) e2315190121, 1-11. doi: 10.1073/pnas.2315190121
2024
Journal Article
Exposure to endocrine-disrupting plasticisers and lung function in children and adolescents: a systematic review and meta-analysis
Boissiere-O’Neill, Thomas, Lee, Wen R., Blake, Tamara L., Sly, Peter D. and Vilcins, Dwan (2024). Exposure to endocrine-disrupting plasticisers and lung function in children and adolescents: a systematic review and meta-analysis. Environmental Research, 243 117751, 117751. doi: 10.1016/j.envres.2023.117751
2024
Journal Article
Cord blood lipid correlation network profiles are associated with subsequent attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms at 2 years: a prospective birth cohort study
Vacy, Kristina, Thomson, Sarah, Moore, Archer, Eisner, Alex, Tanner, Sam, Pham, Cindy, Saffery, Richard, Mansell, Toby, Burgner, David, Collier, Fiona, Vuillermin, Peter, O’Hely, Martin, Boon, Wah Chin, Meikle, Peter, Burugupalli, Satvika, Ponsonby, Anne-Louise, Tang, Mimi L.K., Gray, Lawrence, Ranganathan, Sarath, Sly, Peter (Barwon Infant Study Investigator Group), Mueller, Jochen (Barwon Infant Study Investigator Group), Dwyerm, Terry, Carlin, John and Barwon Infant Study Investigator Group (2024). Cord blood lipid correlation network profiles are associated with subsequent attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms at 2 years: a prospective birth cohort study. eBioMedicine, 100 104949, 1-19. doi: 10.1016/j.ebiom.2023.104949
2024
Journal Article
Association of antenatal and early childhood air pollution and greenspace exposures with respiratory pathogen upper airway acquisitions and respiratory health outcomes
Takashima, Mari D., Grimwood, Keith, Vilcins, Dwan, Knibbs, Luke D., Sly, Peter D., Lambert, Stephen B. and Ware, Robert S. (2024). Association of antenatal and early childhood air pollution and greenspace exposures with respiratory pathogen upper airway acquisitions and respiratory health outcomes. International Journal of Environmental Health Research, 34 (9), 3147-3160. doi: 10.1080/09603123.2023.2299225
2024
Journal Article
Azithromycin Augments Bacterial Uptake and Anti-Inflammatory Macrophage Polarization in Cystic Fibrosis
Tarique, Abdullah A., Tuladhar, Neeraj, Kelk, Dean, Begum, Nelufa, Lucas, Richard M., Luo, Lin, Stow, Jennifer L., Wainwright, Claire E., Bell, Scott C., Sly, Peter D. and Fantino, Emmanuelle (2024). Azithromycin Augments Bacterial Uptake and Anti-Inflammatory Macrophage Polarization in Cystic Fibrosis. Cells, 13 (2) 166, 166. doi: 10.3390/cells13020166
2024
Journal Article
Updates in air pollution: current research and future challenges
Vilcins, Dwan, Christofferson, Rebecca C., Yoon, Jin-Ho, Nazli, Siti Nurshahida, Sly, Peter D., Cormier, Stephania A. and Shen, Guofeng (2024). Updates in air pollution: current research and future challenges. Annals of Global Health, 90 (1) 9, 9. doi: 10.5334/aogh.4363
2024
Journal Article
The DmsABC S-oxide reductase is an essential component of a novel, hypochlorite-inducible system of extracellular stress defense in Haemophilus influenzae
Nasreen, Marufa, Ellis, Daniel, Hosmer, Jennifer, Essilfie, Ama-Tawiah, Fantino, Emmanuelle, Sly, Peter, McEwan, Alastair G. and Kappler, Ulrike (2024). The DmsABC S-oxide reductase is an essential component of a novel, hypochlorite-inducible system of extracellular stress defense in Haemophilus influenzae. Frontiers in Microbiology, 15 1359513. doi: 10.3389/fmicb.2024.1359513
2024
Journal Article
Emotional symptoms and inflammatory biomarkers in childhood: associations in two Australian birth cohorts
Lange, Katherine, Pham, Cindy, Fedyszyn, Izabela E., Cook, Fallon, Burgner, David P., Olsson, Craig A., Downes, Marnie, Priest, Naomi, Mansell, Toby, Tang, Mimi L.K., Ponsonby, Anne-Louise, Symeonides, Christos, Loughman, Amy, Vuillermin, Peter, Kerr, Jessica A., Gray, Lawrence, Sly, Peter D., Lycett, Kate, Carlin, John B., Saffery, Richard, Wake, Melissa and O'Connor, Meredith (2024). Emotional symptoms and inflammatory biomarkers in childhood: associations in two Australian birth cohorts. Journal of Affective Disorders, 344, 356-364. doi: 10.1016/j.jad.2023.10.042
2024
Journal Article
Microplastics in the Asia-Pacific region in the Plasticene Era: exposures and health risks
Sly, Peter, Nabhani, Khadija Al, Sripada, Kam and Kayama, Fujio (2024). Microplastics in the Asia-Pacific region in the Plasticene Era: exposures and health risks. Annals of Global Health, 90 (1), 8-15. doi: 10.5334/aogh.4326
2024
Journal Article
Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis
Chen, Yuxin, Charbonnier, Jean-Paul, Andrinopoulou, Eleni-Rosalina, Sly, Peter D., Stick, Stephen M. and Tiddens, Harm A.W.M. (2024). Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis. Journal of Cystic Fibrosis, 23 (5), 870-873. doi: 10.1016/j.jcf.2024.04.001
2023
Journal Article
Sustainable environments for Australian children's and young people's health and wellbeing: our young's welfare is threatened
Sly, Peter D. and Stanley, Fiona J. (2023). Sustainable environments for Australian children's and young people's health and wellbeing: our young's welfare is threatened. Medical Journal of Australia, 219 (S10), S40-S43. doi: 10.5694/mja2.52133
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Sly is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Respiratory Guidelines for the Management of Paediatric Neuromuscular Disease
Principal Advisor
Other advisors: Dr Zephanie Tyack
-
Doctor Philosophy
Role of airway obstruction in the development of asthma
Principal Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Characterising the Environmental Burden of E-waste and its Impacts on Children¿s and Women's Health
Principal Advisor
-
Doctor Philosophy
Maternal exposure to phthalates and allergic disease in children
Principal Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia: From research to policy
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
-
Doctor Philosophy
Evaluation of Integrated Surveillance of Antimicrobial Resistance in South and South East Asian Countries
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
Completed supervision
-
2023
Doctor Philosophy
Traffic-related air pollution: impact on respiratory health and attitudes to self-protective behaviours amongst urban Vietnamese children
Principal Advisor
Other advisors: Associate Professor Phong Thai, Dr Dung Phung
-
2020
Doctor Philosophy
Enteropathogen infection and Household Factors Associated with Linear Child Growth in Bangladesh
Principal Advisor
-
2020
Doctor Philosophy
Novel green space measures and birthweight in Queensland, Australia
Principal Advisor
Other advisors: Professor Paul Jagals, Dr Peter Baker
-
2019
Doctor Philosophy
Incorporating Epidemiological Studies into Integrated Environmental Health Impact Assessment of Coal Mining
Principal Advisor
Other advisors: Professor Paul Jagals
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2019
Doctor Philosophy
Evaluating the Effects of Atmospheric Environment on Children's Health in Hanoi, Vietnam
Principal Advisor
Other advisors: Professor Jochen Mueller, Associate Professor Phong Thai, Dr Dung Phung
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2018
Doctor Philosophy
Assessing Exposure of Young Australian Children to Toxicants in the Home Environment using a Web-Based Questionnaire
Principal Advisor
Other advisors: Professor Paul Jagals
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2018
Doctor Philosophy
Improving the clinical utility of the Forced Oscillation Technique in preschool-aged children
Principal Advisor
-
2023
Doctor Philosophy
Children's Environmental Health in Least Developed Countries: a modelling approach to support policy decisions
Associate Advisor
Other advisors: Professor Paul Jagals
-
2023
Doctor Philosophy
Trajectories of asthma symptom and their associations with family, neighbourhood, and psychosocial environmental factors among children in Australia
Associate Advisor
Other advisors: Associate Professor Abdullah Mamun
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2022
Master Philosophy
Investigating the molecular mechanisms of macrophage polarisation
Associate Advisor
Other advisors: Dr Abdullah Tarique, Dr Emmanuelle Fantino
-
2022
Doctor Philosophy
The airway epithelium: oxidative stress and environment
Associate Advisor
Other advisors: Dr Emmanuelle Fantino
-
2021
Doctor Philosophy
Assessing Early-life Human Exposure to Selected Pesticides Using Urinary Biomarkers
Associate Advisor
Other advisors: Professor Jochen Mueller
-
2020
Doctor Philosophy
Statistical methods for analysing the health effects of prenatal exposure to mixtures of correlated endocrine-disrupting chemicals
Associate Advisor
-
2020
Doctor Philosophy
Early Life Predictors of Peak Lung function at 21 years Findings from a Longitudinal Cohort Study
Associate Advisor
Other advisors: Associate Professor Abdullah Mamun
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2019
Doctor Philosophy
Establishing a wound healing model in well differentiated cultures of primary human nasal epithelial cells
Associate Advisor
Other advisors: Dr Emmanuelle Fantino
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2017
Doctor Philosophy
Assessing body burden of persistent organic pollutants (POPs) in infants/toddlers through analysis of faeces
Associate Advisor
Other advisors: Professor Jochen Mueller
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2016
Doctor Philosophy
The antiviral defects of the airway epithelium associated with wheeze and atopy in children and asthma in adults
Associate Advisor
Other advisors: Dr Emmanuelle Fantino
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2016
Doctor Philosophy
Macrophage polarization and function in cystic fibrosis
Associate Advisor
Other advisors: Dr Emmanuelle Fantino
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2015
Doctor Philosophy
Immunomodulation of allergic airway inflammation by mesenchymal stem cells
Associate Advisor
-
2014
Doctor Philosophy
Acute lower respiratory infections in infants in the tropics: Environmental drivers of seasonal epidemics
Associate Advisor
Other advisors: Emeritus Professor Gail Williams
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2014
Doctor Philosophy
Assessing environmental exposures in Australian children. A case study of bisphenol A
Associate Advisor
Other advisors: Professor Jochen Mueller
Media
Enquiries
Contact Professor Peter Sly directly for media enquiries about:
- Child health
- Children and environment
- Cystic fibrosis
- Paediatric asthma
- Respiratory physiology
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