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Dr Duy Phan
Dr

Duy Phan

Email: 
Phone: 
+61 7 344 36267

Overview

Background

I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.

Availability

Dr Duy Phan is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Cambridge

Works

Search Professor Duy Phan’s works on UQ eSpace

120 works between 2006 and 2024

1 - 20 of 120 works

Featured

2022

Journal Article

Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131

Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21

Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131

Featured

2021

Journal Article

Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component

Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697

Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component

Featured

2020

Journal Article

Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0

Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

Featured

2020

Journal Article

Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli

Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023

Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli

2024

Conference Publication

A novel cell-free multi-omics approach for enhancing multi-cancer early detection

Nguyen, Thien-Chi Van Van, Nguyen, Anh-Nhu, Nguyen, Thien-Phuc Hoang, Nguyen, Hanh Thi-Hue, Tran, Trung-Hieu, Nguyen, Tien-Anh, Tran, Trang Thi, Nguyen, Trong Hieu, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai-Nghia and Tran, Le Son (2024). A novel cell-free multi-omics approach for enhancing multi-cancer early detection. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.103

A novel cell-free multi-omics approach for enhancing multi-cancer early detection

2024

Conference Publication

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

Doan, Nhu Nhat Tan, Nguyen, Trong Hieu, Tran, Trung Hieu, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology (ASCO). doi: 10.1200/jco.2024.42.23_suppl.224

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

2024

Conference Publication

Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants

Tran, Le Son, Nguyen, Thi Hue Hanh, Nguyen, Luu Hong Dang, Nguyen, Trong Hieu, Nguyen, Thanh Dat, Giang, Hoa, Phan, Minh Duy, Nguyen, Duy Sinh, Tang, Hung Sang and Nguyen, Hoai-Nghia (2024). Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.102

Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants

2024

Conference Publication

Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors

Van, Thi Tuong Vi, Nguyen, Hanh Thi-Hue, Nguyen, Thien-Chi Van Van, Vo, Dac Ho, Tran, Trung Hieu, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Huynh, Le Anh Khoa, Nguyen, Xuan Vinh, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai Nghia and Tran, Le Son (2024). Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.7

Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors

2024

Journal Article

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Tran, Trung Hieu, Huynh, Le Anh Khoa, Doan, Phuoc Loc, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Nguyen, Giang Thi Huong, Nguyen, Hoai-Nghia, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. Journal of Translational Medicine, 22 (1) 618. doi: 10.1186/s12967-024-05416-z

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

2024

Conference Publication

Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection

Tran, Le Son, Nguyen, Luu Hong Dang, Nguyen, Hanh Thi-Hue, Nguyen, Duy Sinh, Tang, Hung Sang, Giang, Hoa, Nguyen, Hoai-Nghia and Phan, Minh-Duy (2024). Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection. 2024 ASCO Annual Meeting, Chicago, IL United States, 31 May - 4 June 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.16_suppl.10548

Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection

2024

Journal Article

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

2024

Journal Article

The genetic landscape of chromosomal aberrations in 3776 Vietnamese fetuses with clinical anomalies during pregnancy

Tran, Danh-Cuong, Phan, Minh Ngoc, Dao, Hong-Thuy Thi, Nguyen, Hong-Dang Luu, Nguyen, Duy-Anh, Le, Quang Thanh, Hoang, Diem-Tuyet Thi, Tran, Nhat Thang, Thi Ha, Thi Minh, Dinh, Thuy Linh, Nguyen, Canh Chuong, Thi Doan, Kim Phuong, Thi Luong, Lan Anh, Vo, Ta Son, Nhat Trinh, Thu Huong, Nguyen, Van Thong, Vo, Phuong-Anh Ngoc, Nguyen, Yen-Nhi, Dinh, My-An, Doan, Phuoc-Loc, Do, Thanh-Thuy Thi, Nguyen, Quynh-Tho Thi, Truong, Dinh-Kiet, Nguyen, Hoai-Nghia, Phan, Minh-Duy, Tang, Hung-Sang and Giang, Hoa (2024). The genetic landscape of chromosomal aberrations in 3776 Vietnamese fetuses with clinical anomalies during pregnancy. Personalized Medicine, 1-9. doi: 10.2217/pme-2023-0113

The genetic landscape of chromosomal aberrations in 3776 Vietnamese fetuses with clinical anomalies during pregnancy

2024

Journal Article

A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria

Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4

A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria

2024

Journal Article

THIẾT LẬP VÀ ĐÁNH GIÁ QUI TRÌNH SÀNG LỌC TRƯỚC SINH KHÔNG XÂM LẤN CHO HỘI CHỨNG MẤT ĐOẠN 22Q11.2

Nguyễn, Phạm Trường Vinh, Phạm, Thị Thuỳ Trang, Đỗ, Thị Thanh Thủy, Trương, Đình Kiệt, Tăng, Hùng Sang, Nguyễn, Hoài Nghĩa, Nguyễn, Thị Tường Vy, Giang, Hoa, Phan, Minh Duy, Nguyễn, Vạn Thông, Võ, Tá Sơn, Trần, Nhật Thăng, Nguyễn, Cảnh Chương, Tăng, Xuân Hải, Phạm, Thái Hạ, Nguyễn, Thị Bích Vân and Hà, Thị Minh Thi (2024). THIẾT LẬP VÀ ĐÁNH GIÁ QUI TRÌNH SÀNG LỌC TRƯỚC SINH KHÔNG XÂM LẤN CHO HỘI CHỨNG MẤT ĐOẠN 22Q11.2. Tạp chí Y học Việt Nam, 535 (1B). doi: 10.51298/vmj.v535i1b.8400

THIẾT LẬP VÀ ĐÁNH GIÁ QUI TRÌNH SÀNG LỌC TRƯỚC SINH KHÔNG XÂM LẤN CHO HỘI CHỨNG MẤT ĐOẠN 22Q11.2

2024

Journal Article

Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant <i>Escherichia coli</i> ST131

Phan, Minh-Duy, Schirra, Horst Joachim, Nhu, Nguyen Thi Khanh, Peters, Kate M., Sarkar, Sohinee, Allsopp, Luke P., Achard, Maud E. S., Kappler, Ulrike and Schembri, Mark A. (2024). Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131. mBio, 15 (3), e0338823. doi: 10.1128/mbio.03388-23

Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant <i>Escherichia coli</i> ST131

2023

Journal Article

<i>De novo</i> variants of dominant monogenic disorders in Vietnam detected by a noninvasive prenatal test: a case series

Tran, Nhat-Thang, Vo, Son Ta, Nguyen, Duy-Anh, Nguyen, Canh-Chuong, Dinh, Linh Thuy, Tran, Minh-Thu Thi, Tran, Danh-Cuong, Luong, Lan-Anh Thi, Doan, Kim-Phuong, Huy Nguyen, Vu Quoc, Thi Ha, Thi Minh, Truong, Linh-Giang Thi, Cao, Phuong Thi-Mai, Tran, Vy Thi-Nhat, Nhut Trinh, Thu Huong, Le, Quang Thanh, Nguyen, Van Thong, Hoang, Diem-Tuyet Thi, Nguyen, My-Nhi Ba, Bui, Chi-Thuong, Tran, Son-Tra Thi, Lam, Duc-Tam, Le, Hong-Thinh, Nguyen, My-Ngoc Ba, Ho, Viet-Thang, Nguyen, Minh-Trung, Dao, Trang Thi, Nguyen, Phuong Minh, Nguyen, Thu-Hang Le ... Tang, Hung-Sang (2023). De novo variants of dominant monogenic disorders in Vietnam detected by a noninvasive prenatal test: a case series. Personalized Medicine, 20 (6), 467-475. doi: 10.2217/pme-2023-0105

<i>De novo</i> variants of dominant monogenic disorders in Vietnam detected by a noninvasive prenatal test: a case series

2023

Journal Article

Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam

Huynh, Tuan-Binh, Mai-Hoang, Thuy-Dung, Bui-Nguyen, Tram-Anh, Ha, Trinh Thi Phuong, Phan, Minh-Duy and Tran-Van, Hieu (2023). Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam. Aquaculture and Fisheries. doi: 10.1016/j.aaf.2023.10.004

Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam

2023

Journal Article

Effects of Ocimum basilicum mucilage on hyperlipidemia and gut microbiota on mice fed a high-fat diet

Nguyen-Le, Duy, Nguyen, Cao-Tri, Ngo-Phan, Minh-Vu, Tran, Thuoc Linh, Phan, Minh-Duy, Unno, Tatsuya and Tran-Van, Hieu (2023). Effects of Ocimum basilicum mucilage on hyperlipidemia and gut microbiota on mice fed a high-fat diet. Bioactive Carbohydrates and Dietary Fibre, 30 100384, 1-9. doi: 10.1016/j.bcdf.2023.100384

Effects of Ocimum basilicum mucilage on hyperlipidemia and gut microbiota on mice fed a high-fat diet

2023

Journal Article

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Pham, Thi Mong Quynh, Nguyen, Giang Thi Huong, Nguyen, Thanh Dat, Tran, Thuy Thi Thu, Vo, Duy Long, Phan, Thanh Hai, Jasmine, Thanh Xuan, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Trieu Vu, Nguyen, Thi Hue Hanh, Huynh, Le Anh Khoa, Tran, Trung Hieu, Dang, Quang Thong, Doan, Thuy Nguyen, Tran, Anh Minh, Nguyen, Viet Hai, Nguyen, Vu Tuan Anh, Ho, Le Minh Quoc, Tran, Quang Dat, Pham, Thi Thu Thuy, Ho, Tan Dat, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Nguyen, Thanh Dang, Phu, Dung Thai Bieu ... Tran, Le Son (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. eLife, 12 89083, 1-28. doi: 10.7554/eLife.89083

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

2023

Journal Article

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Pham, Thi Mong Quynh, Nguyen, Giang Thi Huong, Nguyen, Thanh Dat, Tran, Thuy Thi Thu, Vo, Duy Long, Phan, Thanh Hai, Jasmine, Thanh Xuan, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Trieu Vu, Nguyen, Thi Hue Hanh, Huynh, Le Anh Khoa, Tran, Trung Hieu, Dang, Quang Thong, Doan, Thuy Nguyen, Tran, Anh Minh, Nguyen, Viet Hai, Nguyen, Vu Tuan Anh, Ho, Le Minh Quoc, Tran, Quang Dat, Pham, Thi Thu Thuy, Ho, Tan Dat, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Nguyen, Thanh Dang, Phu, Dung Thai Bieu ... Tran, Le Son (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. eLife, 12, 1-28. doi: 10.7554/elife.89083.3

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Funding

Current funding

  • 2024 - 2028
    Unlocking the gut microbiome to track the spread of AMR genes and pathogens
    NHMRC MRFF - Global Health Initiative
    Open grant
  • 2021 - 2025
    How a multidrug resistant bacterial pathogen has become pandemic
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2023
    Understanding the role of specific virulence features in extra-intestinal E. coli clones
    NHMRC IDEAS Grants
    Open grant

Supervision

Availability

Dr Duy Phan is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

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