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Dr Duy Phan
Dr

Duy Phan

Email: 
Phone: 
+61 7 344 36267

Overview

Background

I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.

Availability

Dr Duy Phan is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Cambridge

Works

Search Professor Duy Phan’s works on UQ eSpace

131 works between 2006 and 2024

1 - 20 of 131 works

Featured

2022

Journal Article

Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131

Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21

Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131

Featured

2021

Journal Article

Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component

Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697

Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component

Featured

2020

Journal Article

Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0

Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

Featured

2020

Journal Article

Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli

Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023

Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli

2024

Journal Article

The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization

Pham, Thi Mong Quynh, Nguyen, Thanh Nhan, Tran Nguyen, Bui Que, Diem Tran, Thi Phuong, Diem Pham, Nguyen My, Phuc Nguyen, Hoang Thien, Cuong Ho, Thi Kim, Linh Nguyen, Dinh Viet, Nguyen, Huu Thinh, Tran, Duc Huy, Tran, Thanh Sang, Pham, Truong Vinh Ngoc, Le, Minh Triet, Vy Nguyen, Thi Tuong, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2024). The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization. eLife, 13. doi: 10.7554/elife.94658.3

The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization

2024

Journal Article

Evolution of the pheV-tRNA integrated genomic island in Escherichia coli

Nhu, Nguyen Thi Khanh, Forde, Brian M., Ben Zakour, Nouri L., Phan, Minh-Duy, Roberts, Leah W., Beatson, Scott A. and Schembri, Mark A. (2024). Evolution of the pheV-tRNA integrated genomic island in Escherichia coli. PLoS Genetics, 20 (10) e1011459, e1011459. doi: 10.1371/journal.pgen.1011459

Evolution of the pheV-tRNA integrated genomic island in Escherichia coli

2024

Journal Article

Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests

Thien Nguyen, Chi Van, Hanh Nguyen, Thi Hue, Vo, Dac Ho, Vi Van, Thi Tuong, Huong Nguyen, Giang Thi, Tran, Trung Hieu, Nguyen, Trong Hieu, Khoa Huynh, Le Anh, Nguyen, Thanh Dat, Tran, Nhat-Huy, Thi Ha, Thi Minh, Quynh Le, Phan Tuong, Truong, Xuan Long, Nguyen, Hong-Dang Luu, Tran, Uyen Vu, Hoang, Thanh Quang, Nguyen, Viet Binh, Le, Van Cuong, Nguyen, Xuan Chung, Phuong Nguyen, Thi Minh, Nguyen, Van Hung, Nhat Tran, Nu Thien, Quynh Dang, Thi Ngoc, Tran, Manh Hoang, Nguyen, Phuc Nguyen, Dao, Thi Huyen, Phuc Nguyen, Huu Tam, Tran, Nhat-Thang, Phan, Thi Van ... Tran, Le Son (2024). Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests. Future Oncology, ahead-of-print (ahead-of-print), 1-11. doi: 10.1080/14796694.2024.2413266

Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests

2024

Journal Article

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales

Graf, Fabrice E., Goodman, Richard N., Gallichan, Sarah, Forrest, Sally, Picton-Barlow, Esther, Fraser, Alice J., Phan, Minh-Duy, Mphasa, Madalitso, Hubbard, Alasdair T. M., Musicha, Patrick, Schembri, Mark A., Roberts, Adam P., Edwards, Thomas, Lewis, Joseph M. and Feasey, Nicholas A. (2024). Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales. Nature Communications, 15 (1) 9019, 1-12. doi: 10.1038/s41467-024-53391-2

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales

2024

Journal Article

Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women

Vinh, Dao Nguyen, Thi Ngoc Nguyen, Thanh, Nguyen Tran, Tuan-Anh, Doan, Phuoc-Loc, Nguyen Hoang, Van-Anh, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia, Nguyen, Hue Thi and Tu, Lan N. (2024). Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women. BJC Reports, 2 (1) 80. doi: 10.1038/s44276-024-00100-7

Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women

2024

Journal Article

The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen

White, Rhys T., Ashcroft, Melinda M., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Minh-Duy, Roberts, Leah W., Rogers, Benjamin A., Schembri, Mark A., Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen. Access Microbiology, 6 (10). doi: 10.1099/acmi.0.000894.v3

The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen

2024

Journal Article

Modified Tn <i>7</i> transposon vectors for controlled chromosomal gene expression

Chang, Chyden, Phan, Minh-Duy and Schembri, Mark A. (2024). Modified Tn 7 transposon vectors for controlled chromosomal gene expression. Applied and Environmental Microbiology, 90 (10) e01556-24, e0155624. doi: 10.1128/aem.01556-24

Modified Tn <i>7</i> transposon vectors for controlled chromosomal gene expression

2024

Journal Article

A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study

Dang Nguyen, Luu Hong, Tieu, Ba Linh, Nguyen, Thi Thanh, Ha, Nhung Phuong, Huong Nguyen, Giang Thi, Hanh Nguyen, Thi Hue, Le, Van Hoi, Bui, Vinh Quang, Nguyen, Lan Hieu, Pham, Nhu Hiep, Phan, Thanh Hai, Nguyen, Huu Thinh, Tran, Van Song, Bui, Chi Viet, Vo, Van Kha, Nhan Nguyen, Pham Thanh, Phuoc Dang, Ha Huu, Pham, Van Dung, Cao, Van Thinh, Phan, Ngoc Minh, Nguyen, Van Tung, Quyen Le, Thi Le, Luong, Thi Lan-Anh, Phuong Doan, Thi Kim, Phan, Canh Duy, Nguyen, Thanh Xuan, Pham, Nguyen Tuong, Nguyen, Bao Toan, Thuy Pham, Thi Thu ... Nguyen, Duy Sinh (2024). A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study. Future Science OA, 10 (1). doi: 10.1080/20565623.2024.2395244

A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study

2024

Other Outputs

The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.

White, Rhys T., Ashcroft, Melinda A., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Duy, Roberts, Leah W., Rogers, Benjamin, Schembri, Mark, Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.. doi: 10.1099/acmi.0.000894.v2

The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.

2024

Conference Publication

A novel cell-free multi-omics approach for enhancing multi-cancer early detection

Nguyen, Thien-Chi Van Van, Nguyen, Anh-Nhu, Nguyen, Thien-Phuc Hoang, Nguyen, Hanh Thi-Hue, Tran, Trung-Hieu, Nguyen, Tien-Anh, Tran, Trang Thi, Nguyen, Trong Hieu, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai-Nghia and Tran, Le Son (2024). A novel cell-free multi-omics approach for enhancing multi-cancer early detection. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.103

A novel cell-free multi-omics approach for enhancing multi-cancer early detection

2024

Conference Publication

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

Doan, Nhu Nhat Tan, Nguyen, Trong Hieu, Tran, Trung Hieu, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology (ASCO). doi: 10.1200/jco.2024.42.23_suppl.224

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

2024

Conference Publication

Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants

Tran, Le Son, Nguyen, Thi Hue Hanh, Nguyen, Luu Hong Dang, Nguyen, Trong Hieu, Nguyen, Thanh Dat, Giang, Hoa, Phan, Minh Duy, Nguyen, Duy Sinh, Tang, Hung Sang and Nguyen, Hoai-Nghia (2024). Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.102

Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants

2024

Conference Publication

Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors

Van, Thi Tuong Vi, Nguyen, Hanh Thi-Hue, Nguyen, Thien-Chi Van Van, Vo, Dac Ho, Tran, Trung Hieu, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Huynh, Le Anh Khoa, Nguyen, Xuan Vinh, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai Nghia and Tran, Le Son (2024). Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.7

Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors

2024

Journal Article

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Tran, Trung Hieu, Huynh, Le Anh Khoa, Doan, Phuoc Loc, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Nguyen, Giang Thi Huong, Nguyen, Hoai-Nghia, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. Journal of Translational Medicine, 22 (1) 618. doi: 10.1186/s12967-024-05416-z

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

2024

Conference Publication

Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection

Tran, Le Son, Nguyen, Luu Hong Dang, Nguyen, Hanh Thi-Hue, Nguyen, Duy Sinh, Tang, Hung Sang, Giang, Hoa, Nguyen, Hoai-Nghia and Phan, Minh-Duy (2024). Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection. 2024 ASCO Annual Meeting, Chicago, IL United States, 31 May - 4 June 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.16_suppl.10548

Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection

2024

Journal Article

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

Funding

Current funding

  • 2024 - 2028
    Unlocking the gut microbiome to track the spread of AMR genes and pathogens
    NHMRC MRFF - Global Health Initiative
    Open grant
  • 2021 - 2025
    How a multidrug resistant bacterial pathogen has become pandemic
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2023
    Understanding the role of specific virulence features in extra-intestinal E. coli clones
    NHMRC IDEAS Grants
    Open grant

Supervision

Availability

Dr Duy Phan is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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