Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
Featured
2022
Journal Article
Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131
Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21
Featured
2021
Journal Article
Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component
Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697
Featured
2020
Journal Article
Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB
Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0
Featured
2020
Journal Article
Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli
Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023
2024
Journal Article
The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization
Pham, Thi Mong Quynh, Nguyen, Thanh Nhan, Tran Nguyen, Bui Que, Diem Tran, Thi Phuong, Diem Pham, Nguyen My, Phuc Nguyen, Hoang Thien, Cuong Ho, Thi Kim, Linh Nguyen, Dinh Viet, Nguyen, Huu Thinh, Tran, Duc Huy, Tran, Thanh Sang, Pham, Truong Vinh Ngoc, Le, Minh Triet, Vy Nguyen, Thi Tuong, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2024). The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization. eLife, 13. doi: 10.7554/elife.94658.3
2024
Journal Article
Evolution of the pheV-tRNA integrated genomic island in Escherichia coli
Nhu, Nguyen Thi Khanh, Forde, Brian M., Ben Zakour, Nouri L., Phan, Minh-Duy, Roberts, Leah W., Beatson, Scott A. and Schembri, Mark A. (2024). Evolution of the pheV-tRNA integrated genomic island in Escherichia coli. PLoS Genetics, 20 (10) e1011459, e1011459. doi: 10.1371/journal.pgen.1011459
2024
Journal Article
Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests
Thien Nguyen, Chi Van, Hanh Nguyen, Thi Hue, Vo, Dac Ho, Vi Van, Thi Tuong, Huong Nguyen, Giang Thi, Tran, Trung Hieu, Nguyen, Trong Hieu, Khoa Huynh, Le Anh, Nguyen, Thanh Dat, Tran, Nhat-Huy, Thi Ha, Thi Minh, Quynh Le, Phan Tuong, Truong, Xuan Long, Nguyen, Hong-Dang Luu, Tran, Uyen Vu, Hoang, Thanh Quang, Nguyen, Viet Binh, Le, Van Cuong, Nguyen, Xuan Chung, Phuong Nguyen, Thi Minh, Nguyen, Van Hung, Nhat Tran, Nu Thien, Quynh Dang, Thi Ngoc, Tran, Manh Hoang, Nguyen, Phuc Nguyen, Dao, Thi Huyen, Phuc Nguyen, Huu Tam, Tran, Nhat-Thang, Phan, Thi Van ... Tran, Le Son (2024). Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests. Future Oncology, ahead-of-print (ahead-of-print), 1-11. doi: 10.1080/14796694.2024.2413266
2024
Journal Article
Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales
Graf, Fabrice E., Goodman, Richard N., Gallichan, Sarah, Forrest, Sally, Picton-Barlow, Esther, Fraser, Alice J., Phan, Minh-Duy, Mphasa, Madalitso, Hubbard, Alasdair T. M., Musicha, Patrick, Schembri, Mark A., Roberts, Adam P., Edwards, Thomas, Lewis, Joseph M. and Feasey, Nicholas A. (2024). Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales. Nature Communications, 15 (1) 9019, 1-12. doi: 10.1038/s41467-024-53391-2
2024
Journal Article
Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women
Vinh, Dao Nguyen, Thi Ngoc Nguyen, Thanh, Nguyen Tran, Tuan-Anh, Doan, Phuoc-Loc, Nguyen Hoang, Van-Anh, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia, Nguyen, Hue Thi and Tu, Lan N. (2024). Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women. BJC Reports, 2 (1) 80. doi: 10.1038/s44276-024-00100-7
2024
Journal Article
The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen
White, Rhys T., Ashcroft, Melinda M., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Minh-Duy, Roberts, Leah W., Rogers, Benjamin A., Schembri, Mark A., Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen. Access Microbiology, 6 (10). doi: 10.1099/acmi.0.000894.v3
2024
Journal Article
Modified Tn <i>7</i> transposon vectors for controlled chromosomal gene expression
Chang, Chyden, Phan, Minh-Duy and Schembri, Mark A. (2024). Modified Tn 7 transposon vectors for controlled chromosomal gene expression. Applied and Environmental Microbiology, 90 (10) e01556-24, e0155624. doi: 10.1128/aem.01556-24
2024
Journal Article
A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study
Dang Nguyen, Luu Hong, Tieu, Ba Linh, Nguyen, Thi Thanh, Ha, Nhung Phuong, Huong Nguyen, Giang Thi, Hanh Nguyen, Thi Hue, Le, Van Hoi, Bui, Vinh Quang, Nguyen, Lan Hieu, Pham, Nhu Hiep, Phan, Thanh Hai, Nguyen, Huu Thinh, Tran, Van Song, Bui, Chi Viet, Vo, Van Kha, Nhan Nguyen, Pham Thanh, Phuoc Dang, Ha Huu, Pham, Van Dung, Cao, Van Thinh, Phan, Ngoc Minh, Nguyen, Van Tung, Quyen Le, Thi Le, Luong, Thi Lan-Anh, Phuong Doan, Thi Kim, Phan, Canh Duy, Nguyen, Thanh Xuan, Pham, Nguyen Tuong, Nguyen, Bao Toan, Thuy Pham, Thi Thu ... Nguyen, Duy Sinh (2024). A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study. Future Science OA, 10 (1). doi: 10.1080/20565623.2024.2395244
2024
Other Outputs
The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.
White, Rhys T., Ashcroft, Melinda A., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Duy, Roberts, Leah W., Rogers, Benjamin, Schembri, Mark, Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.. doi: 10.1099/acmi.0.000894.v2
2024
Conference Publication
A novel cell-free multi-omics approach for enhancing multi-cancer early detection
Nguyen, Thien-Chi Van Van, Nguyen, Anh-Nhu, Nguyen, Thien-Phuc Hoang, Nguyen, Hanh Thi-Hue, Tran, Trung-Hieu, Nguyen, Tien-Anh, Tran, Trang Thi, Nguyen, Trong Hieu, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai-Nghia and Tran, Le Son (2024). A novel cell-free multi-omics approach for enhancing multi-cancer early detection. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.103
2024
Conference Publication
Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
Doan, Nhu Nhat Tan, Nguyen, Trong Hieu, Tran, Trung Hieu, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology (ASCO). doi: 10.1200/jco.2024.42.23_suppl.224
2024
Conference Publication
Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants
Tran, Le Son, Nguyen, Thi Hue Hanh, Nguyen, Luu Hong Dang, Nguyen, Trong Hieu, Nguyen, Thanh Dat, Giang, Hoa, Phan, Minh Duy, Nguyen, Duy Sinh, Tang, Hung Sang and Nguyen, Hoai-Nghia (2024). Comprehensive validation of a cell-free DNA-based assay for multi-cancer detection: A Vietnamese longitudinal prospective cohort study of 9,024 participants. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.102
2024
Conference Publication
Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors
Van, Thi Tuong Vi, Nguyen, Hanh Thi-Hue, Nguyen, Thien-Chi Van Van, Vo, Dac Ho, Tran, Trung Hieu, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Huynh, Le Anh Khoa, Nguyen, Xuan Vinh, Giang, Hoa, Phan, Minh-Duy, Nguyen, Hoai Nghia and Tran, Le Son (2024). Multimodal analysis of methylation and fragmentomic profiles in plasma cell free DNA for differentiation of benign and malignant breast tumors. ASCO Breakthrough 2024, Yokohama, Japan, 8-10 August 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.23_suppl.7
2024
Journal Article
Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Tran, Trung Hieu, Huynh, Le Anh Khoa, Doan, Phuoc Loc, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Nguyen, Giang Thi Huong, Nguyen, Hoai-Nghia, Giang, Hoa, Tran, Le Son and Phan, Minh Duy (2024). Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks. Journal of Translational Medicine, 22 (1) 618. doi: 10.1186/s12967-024-05416-z
2024
Conference Publication
Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection
Tran, Le Son, Nguyen, Luu Hong Dang, Nguyen, Hanh Thi-Hue, Nguyen, Duy Sinh, Tang, Hung Sang, Giang, Hoa, Nguyen, Hoai-Nghia and Phan, Minh-Duy (2024). Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection. 2024 ASCO Annual Meeting, Chicago, IL United States, 31 May - 4 June 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.16_suppl.10548
2024
Journal Article
High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
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