Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
Featured
2022
Journal Article
Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131
Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21
Featured
2021
Journal Article
Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component
Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697
Featured
2020
Journal Article
Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB
Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0
Featured
2020
Journal Article
Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli
Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023
2026
Journal Article
Genomic and AHPND pathogenesis characterization of a novel Vibrio parahaemolyticus strain carrying an ISVal1-like insertion in pirBvp
Huynh, Tuan-Binh, Le, Manh-Liem, Bui-Nguyen, Tram-Anh, Ha, Thi Phuong Trinh, Van, Thi Thu Hao, Vo, Van-Tuan, Phan, Minh-Duy and Tran-Van, Hieu (2026). Genomic and AHPND pathogenesis characterization of a novel Vibrio parahaemolyticus strain carrying an ISVal1-like insertion in pirBvp. Journal of Invertebrate Pathology, 217 108606. doi: 10.1016/j.jip.2026.108606
2026
Journal Article
Natural maternal immunity protects neonates from Escherichia coli sepsis
Diep, Raymond E., Adhikari, Ujjwal, Gokce Tezel, Kubra, Pham, Giang, Burrell, Allison R., Staat, Mary A., Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Schembri, Mark A., Saunders, Scott H., Haslam, David B., Erickson, John J., Chavez-Bueno, Susana and Way, Sing Sing (2026). Natural maternal immunity protects neonates from Escherichia coli sepsis. Nature, 1-9. doi: 10.1038/s41586-026-10225-z
2026
Journal Article
Bacterial reporter–paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense
von Pein, Jessica B., Andersen, Stacey B., Xu, Jon, Phan, Minh-Duy, Dalton, Emma K., Koczerka, Michael, Stocks, Claudia J., Curson, James E. B., Vandeleur, Zoe, Condon, Nicholas D., Hancock, Steven J., Nefzger, Christian M., Palpant, Nathan J., Ramnath, Divya, Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2026). Bacterial reporter–paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense. Proceedings of the National Academy of Sciences, 123 (11) e2530503123, e2530503123. doi: 10.1073/pnas.2530503123
2026
Journal Article
NeuO-mediated O-acetylation of uropathogenic <i>Escherichia coli</i> K1 capsule enhances resistance to phage and neutrophil killing
Walker, Lachlan L., Nhu, Nguyen Thi Khanh, Lian, Zheng Jie, Peters, Kate M., Monteleone, Mercedes, Connolly, James P. R., Walker, Mark J., Forde, Brian M., Schroder, Kate, Sweet, Matthew J., Phan, Minh-Duy and Schembri, Mark A. (2026). NeuO-mediated O-acetylation of uropathogenic Escherichia coli K1 capsule enhances resistance to phage and neutrophil killing. Journal of Bacteriology, 208 (3) e00610-25, e0061025. doi: 10.1128/jb.00610-25
2026
Journal Article
Convergence of plasmid-driven virulence and antibiotic resistance in Escherichia coli
Lian, Zheng Jie, Nhu, Nguyen Thi Khanh, Ravi, Chitra, Chang, Chyden, Martinez-Roman, Irene, Phan, Minh-Duy and Schembri, Mark A. (2026). Convergence of plasmid-driven virulence and antibiotic resistance in Escherichia coli. Nature Communications, 17 (1) 505, 1-13. doi: 10.1038/s41467-025-67202-9
2025
Journal Article
Tumor Genomic and Transcriptomic Analysis Integrated With Liquid Biopsy <scp>ctDNA</scp> Monitoring: Analytical Validation and Clinical Insights
Tran, Nam H. B., Nguyen, Thien‐Phuc Hoang, Bui, Vinh Quang, Le, Vu Thuong, Mai, Trong Khoa, Nguyen Hoang, Van‐Anh, Nguyen, Tien Anh, Nguyen, Minh‐Duc, Pham, Ha‐Hieu, Vo, Tho Thi Le, Ngo, My T. T., Nguyen, Du Quyen, Nguyen, Duy Sinh, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy, Giang, Hoa and Tu, Lan N. (2025). Tumor Genomic and Transcriptomic Analysis Integrated With Liquid Biopsy ctDNA Monitoring: Analytical Validation and Clinical Insights. Cancer Medicine, 14 (23) e71465. doi: 10.1002/cam4.71465
2025
Journal Article
Emergence of a carbapenem-resistant atypical uropathogenic Escherichia coli clone as an increasing cause of urinary tract infection
Walker, Lachlan L., Phan, Minh-Duy, Permana, Budi, Lian, Zheng Jie, Nhu, Nguyen Thi Khanh, Cuddihy, Thom, Peters, Kate M., Ramsay, Kay A., Stewart, Chelsea, Pfennigwerth, Niels, Kidd, Timothy J., Harris, Patrick N. A., Paterson, David L., Sweet, Matthew J., Forde, Brian M. and Schembri, Mark A. (2025). Emergence of a carbapenem-resistant atypical uropathogenic Escherichia coli clone as an increasing cause of urinary tract infection. Nature Communications, 16 (1) 8200, 1-10. doi: 10.1038/s41467-025-63477-0
2025
Journal Article
Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals
Van, Thi Tuong Vi, Tran, Trung Hieu, Nguyen, Thi Hue Hanh, Nguyen, Van Thien Chi, Vo, Dac Ho, Nguyen, Giang Thi Huong, Nguyen, Trong Hieu, To, Kim Sang, Nguyen, Anh Luan, Tran, Cao Hong An, Jasmine, Thanh Xuan, Vo, Thi Loan, Nai, Thi Huong Thoang, Tran, Thuy Trang, Truong, My Hoang, Tran, Ngan Chau, Le, Thi Loc, Nguyen, Thi Hong Nhung, Tu, Ngoc Hieu, Tran, Thanh Son, Le, Bao Toan, Tang, Van Phong, Nguyen, Pham Thanh Nhan, Nguyen, Khac Tien, Ho, Van Chien, Nguyen, Xuan Vinh, Doan, Nhu Nhat Tan, Tran, Thi Trang, Tran, Thi Minh Thu ... Tran, Le Son (2025). Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals. Bmc Biology, 23 (1) 259. doi: 10.1186/s12915-025-02371-z
2025
Journal Article
Cost-effective shallow genome-wide sequencing for profiling plasma cfDNA signatures to enhance lung cancer detection
Nguyen, Van Thien Chi, Vo, Dac Ho, Tran, Thi Trang, Tran, Thanh Truong, Nguyen, Thi Hue Hanh, Vo, Truong Dang Huy, Van, Thi Tuong Vi, Vu, Thi Luyen, Lam, Minh Quang, Nguyen, Giang Thi Huong, Tran, Trung Hieu, Pham, Ngoc Tan, Trac, Quang Thinh, Nguyen, Trong Hieu, Phan, Thi Van, Dao, Thi Huyen, Nguyen, Huu Tam Phuc, Nguyen, Luu Hong Dang, Nguyen, Duy Sinh, Tang, Hung Sang, Giang, Hoa, Phan, Minh Duy, Nguyen, Hoai-Nghia and Tran, Le Son (2025). Cost-effective shallow genome-wide sequencing for profiling plasma cfDNA signatures to enhance lung cancer detection. Future Oncology, 21 (11), 1391-1402. doi: 10.1080/14796694.2025.2483154
2025
Journal Article
Targeting cognitive biases to improve social cognition and social emotional health
Birch, Susan A. J., Stewardson, Charlotte I., Rho, Kate, Kataria, Ashali, Craig, Shannon M., Phan, Minh D. H., Savi, Irene, Voronkova, Kseniia, Lee, Jenny, Choudhary, Gayatri and Torjani, Diba (2025). Targeting cognitive biases to improve social cognition and social emotional health. Frontiers in Psychology, 16 1534125. doi: 10.3389/fpsyg.2025.1534125
2025
Journal Article
Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam
Huynh, Tuan-Binh, Mai-Hoang, Thuy-Dung, Bui-Nguyen, Tram-Anh, Ha, Trinh Thi Phuong, Phan, Minh-Duy and Tran-Van, Hieu (2025). Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam. Aquaculture and Fisheries, 10 (2), 202-209. doi: 10.1016/j.aaf.2023.10.004
2025
Journal Article
Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults
Nguyen, Luu Hong Dang, Nguyen, Thi Hue Hanh, Le, Van Hoi, Bui, Vinh Quang, Nguyen, Lan Hieu, Pham, Nhu Hiep, Phan, Thanh Hai, Nguyen, Huu Thinh, Tran, Van Song, Bui, Chi Viet, Vo, Van Kha, Nguyen, Pham Thanh Nhan, Dang, Ha Huu Phuoc, Pham, Van Dung, Cao, Van Thinh, Phan, Ngoc Minh, Tieu, Ba Linh, Nguyen, Giang Thi Huong, Vo, Dac Ho, Tran, Trung Hieu, Nguyen, Thanh Dat, Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Tran, Vu Uyen, Le, Minh Phong, Tran, Thi Minh Thu, Nguyen Nguyen, Minh, Van, Thi Tuong Vi, Nguyen, Anh Nhu ... Tran, Le Son (2025). Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults. BMC Medicine, 23 (1) 90. doi: 10.1186/s12916-025-03929-y
2025
Journal Article
Combination of hotspot mutations with methylation and fragmentomic profiles to enhance multi‐cancer early detection
Nguyen, Thi Hue Hanh, Vu, Giang Hoang, Nguyen, Tu Thi, Nguyen, Tuan Anh, Tran, Vu Uyen, Vu, Luyen Thi, Nguyen, Giang Thi Huong, Nguyen, Nhat Duy, Tran, Trung Hieu, Nguyen, Van Thien Chi, Nguyen, Thanh Dat, Nguyen, Trong Hieu, Vo, Dac Ho, Van, Thi Tuong Vi, Do, Thanh Thi, Le, Minh Phong, Huynh, Le Anh Khoa, Nguyen, Duy Sinh, Tang, Hung Sang, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy, Giang, Hoa, Tu, Lan N. and Tran, Le Son (2025). Combination of hotspot mutations with methylation and fragmentomic profiles to enhance multi‐cancer early detection. Cancer Medicine, 14 (1) e70575. doi: 10.1002/cam4.70575
2024
Journal Article
epiTCR-KDA: knowledge distillation model on dihedral angles for TCR-peptide prediction
Pham, My-Diem Nguyen, Su, Chinh Tran-To, Nguyen, Thanh-Nhan, Nguyen, Hoai-Nghia, Nguyen, Dinh Duy An, Giang, Hoa, Nguyen, Dinh-Thuc, Phan, Minh-Duy and Nguyen, Vy (2024). epiTCR-KDA: knowledge distillation model on dihedral angles for TCR-peptide prediction. Bioinformatics Advances, 4 (1) vbae190. doi: 10.1093/bioadv/vbae190
2024
Journal Article
The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization
Pham, Thi Mong Quynh, Nguyen, Thanh Nhan, Tran Nguyen, Bui Que, Diem Tran, Thi Phuong, Diem Pham, Nguyen My, Phuc Nguyen, Hoang Thien, Cuong Ho, Thi Kim, Linh Nguyen, Dinh Viet, Nguyen, Huu Thinh, Tran, Duc Huy, Tran, Thanh Sang, Pham, Truong Vinh Ngoc, Le, Minh Triet, Vy Nguyen, Thi Tuong, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2024). The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization. eLife, 13 RP94658, 1-21. doi: 10.7554/elife.94658.3
2024
Journal Article
An ovine septic shock model of live bacterial infusion
Obonyo, Nchafatso G., Raman, Sainath, Suen, Jacky Y., Peters, Kate M., Phan, Minh-Duy, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Palmieri, Chiara, White, Nicole, Sato, Kei, Farah, Samia M., Gandini, Lucia, Liu, Keibun, Fior, Gabriele, Heinsar, Silver, Ijuin, Shinichi, Kyun Ro, Sun, Abbate, Gabriella, Ainola, Carmen, Sato, Noriko, Lundon, Brooke, Portatadino, Sofia, Rachakonda, Reema H., Schneider, Bailey, Harley, Amanda, See Hoe, Louise E., Schembri, Mark A. ... Fraser, John F. (2024). An ovine septic shock model of live bacterial infusion. Intensive Care Medicine Experimental, 12 (1) 94, 1-20. doi: 10.1186/s40635-024-00684-x
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Contribution of the E. coli O-antigen Towards Virulence
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Global regulation of virulence and resistance in uropathogenic E. coli
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
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