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Professor Mark Smithers
Professor

Mark Smithers

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Overview

Background

Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.

He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.

He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.

Availability

Professor Mark Smithers is:
Not available for supervision
Media expert

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Honorary Fellow, American Surgical Association, American Surgical Association
  • Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
  • Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
  • Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England

Research interests

  • Cutaneous Melanoma

    epidemiology, public health issues and management of all stages

  • Management of Oesophageal and Gastric Cancer

    Investigation and management of benign and malignant diseases of the oesophagus and the stomach.

Works

Search Professor Mark Smithers’s works on UQ eSpace

414 works between 1983 and 2025

361 - 380 of 414 works

1999

Conference Publication

The role of chemoradiation on operable carcinoma of the oesophagus trial IG9401

Smithers, B. M. (1999). The role of chemoradiation on operable carcinoma of the oesophagus trial IG9401. Royal Australian College of Surgeons Country Scientific Meeting, John Lindell Theatre, Geelong Hospital, 15-17 Oct, 1999. Melbourne: Royal Australian College of Surgeons Country Scientific Meeting.

The role of chemoradiation on operable carcinoma of the oesophagus trial IG9401

1999

Conference Publication

Palliative chemoradiotherapy (CRT) in advanced oesophageal cancer

Harvey, J., Burmeister, B., Thomson, D., Walpole, E. T., Smithers, B. M. and Gotley, D. C. (1999). Palliative chemoradiotherapy (CRT) in advanced oesophageal cancer. COSA 26th Annual Scientific Meeting, Melbourne Exhibition and Convention Cen., 24-26 Nov, 1999. Melbourne: COSA 26th Annual Scientific Meeting.

Palliative chemoradiotherapy (CRT) in advanced oesophageal cancer

1999

Conference Publication

Elective laparoscopic fundoplication for reflux: 1000 consecutive cases with 1-5 year follow-up

Gotley, D. C., Smithers, B. M., Martin, I., Bessell, J., Doyle, L., Nathanson, L. K. and Menzies, B. L. (1999). Elective laparoscopic fundoplication for reflux: 1000 consecutive cases with 1-5 year follow-up. Australian Gastroenterology Week 1999, Brisbane Convention Cen., 4-8 Oct, 1999. Carlton, Vic.: Blackwell Science Asia.

Elective laparoscopic fundoplication for reflux: 1000 consecutive cases with 1-5 year follow-up

1999

Conference Publication

The role of chemoradiation for oesophageal cancer

Smithers, B. M. (1999). The role of chemoradiation for oesophageal cancer. 12th Biennial Congress of the Asian Surgical Association, Brisbane Convention Centre, 7-11 March 1999. Brisbane: 12th Biennial Congress of the Asian Surgical Association.

The role of chemoradiation for oesophageal cancer

1999

Journal Article

Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy

Thomas, R, Chambers, M, Boytar, R, Barker, K, Cavanagh, LL, MacFadyen, S, Smithers, M, Jenkins, M and Andersen, J (1999). Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy. Melanoma Research, 9 (5), 474-481. doi: 10.1097/00008390-199910000-00007

Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy

1999

Conference Publication

Trends in the management of cutaneous malignant melanoma

Smithers, B. M. (1999). Trends in the management of cutaneous malignant melanoma. Royal Australian College of Surgeons Country Scientific Meeting, John Lindell Theatre, Geelong Hospital, 15-17 Oct, 1999. Melbourne: Royal Aust. College of Surgeons Country Scientific Meeting.

Trends in the management of cutaneous malignant melanoma

1999

Conference Publication

Dysphagia after laparoscopic fundoplication in relation to oesophageal motility and type of wrap

Bessell, J., Finch, R., Gotley, D. C., Nathanson, L. K., Smithers, B. M. and Martin, I. (1999). Dysphagia after laparoscopic fundoplication in relation to oesophageal motility and type of wrap. Cairns International Hotel, 23-25 Sept, 1999. Brisbane: Univ. of Qld..

Dysphagia after laparoscopic fundoplication in relation to oesophageal motility and type of wrap

1999

Conference Publication

Management of pancreatic injuries

Smithers, B. M. (1999). Management of pancreatic injuries. General Surgeons Australia Inaugural Scientific Meeting, Sheraton Mirage, Gold Coast, 6-9 Oct 1999. Brisbane: General Surgeons Aust. Inaugural Scientific Meeting.

Management of pancreatic injuries

1999

Conference Publication

The role of chemoradiotherapy prescribed by a multi-disciplinary team for the palliative treatment of malignant dysphagia

Bessell, J., Smithers, B. M., Gotley, D. C., Martin, I., Harvey, J. and Burmeister, B. (1999). The role of chemoradiotherapy prescribed by a multi-disciplinary team for the palliative treatment of malignant dysphagia. Australian Gastroenterology Week 1999, Brisbane Convention Cen., 4-8 October, 1999. Carlton, Vic.: Blackwell Science Asia.

The role of chemoradiotherapy prescribed by a multi-disciplinary team for the palliative treatment of malignant dysphagia

1999

Conference Publication

High grade dysplasia in Barrett's oesophagus

Sanders, G., Smithers, B. M., Gotley, D. C. and Clouston, A. (1999). High grade dysplasia in Barrett's oesophagus. ArrayAustralian Gastroenterology Week 1999, Brisbane Convention Cen., 4-8 Oct, 1999. Carlton, Vic.: Blackwell Science, Asia.

High grade dysplasia in Barrett's oesophagus

1998

Journal Article

Laparoscopy in the management of diaphragmatic rupture due to blunt trauma

Martin, Ian, O'Rourke, Nicholas, Gotley, David and Smithers, Mark (1998). Laparoscopy in the management of diaphragmatic rupture due to blunt trauma. Australian and New Zealand Journal of Surgery, 68 (8), 584-586. doi: 10.1111/j.1445-2197.1998.tb02105.x

Laparoscopy in the management of diaphragmatic rupture due to blunt trauma

1998

Conference Publication

Automated red cell exchange in sickle cell disease

Cinkotai, KI, Kadkhodaei-Elyaderani, M, Smithers, B, Godbert, F and Adamson, M (1998). Automated red cell exchange in sickle cell disease. OXFORD: BLACKWELL SCIENCE LTD.

Automated red cell exchange in sickle cell disease

1998

Journal Article

Characterization of titanium hydride film after long-term air interaction: SEM, ARXPS and AES depth profile studies

Lisowski, W, van den Berg, AHJ and Smithers, M (1998). Characterization of titanium hydride film after long-term air interaction: SEM, ARXPS and AES depth profile studies. Surface and Interface Analysis, 26 (3), 213-219. doi: 10.1002/(SICI)1096-9918(199803)26:33.3.CO;2-7

Characterization of titanium hydride film after long-term air interaction: SEM, ARXPS and AES depth profile studies

1997

Journal Article

Automated red cell exchange in sickle cell disease [1] (multiple letters)

Olujohungbe, A., Smithers, B., Godbert, F., Adamson, M., Cinkotai, K., Janes, S. L. and Bevan, D. H. (1997). Automated red cell exchange in sickle cell disease [1] (multiple letters). British Journal of Haematology, 99 (1)

Automated red cell exchange in sickle cell disease [1] (multiple letters)

1997

Journal Article

Combined modality therapy for carcinoma of the oesophagus: Current status and future directions

Burmeister, B. H., Smithers, B. M. and Denham, J. W. (1997). Combined modality therapy for carcinoma of the oesophagus: Current status and future directions. Medical Journal of Australia, 167 (7), 349-350. doi: 10.5694/j.1326-5377.1997.tb125097.x

Combined modality therapy for carcinoma of the oesophagus: Current status and future directions

1997

Journal Article

Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb

Wu, Z. Y., Smithers, B. M. and Roberts, M. S. (1997). Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb. Melanoma Research, 7 (3), 252-264. doi: 10.1097/00008390-199706000-00010

Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb

1997

Journal Article

A combined modality approach to the management of oesophageal cancer

Smithers, B. Mark, Devitt, Peter, Jamieson, Glyn G., Bessell, Justin, Gotley, David, Gill, P. Grantley, Neely, Mervyn, Joseph, David J., Yeoh, Eric K., Burmeister, Bryan and Denham, James W. (1997). A combined modality approach to the management of oesophageal cancer. European Journal of Surgical Oncology, 23 (3), 219-223. doi: 10.1016/S0748-7983(97)92364-7

A combined modality approach to the management of oesophageal cancer

1997

Journal Article

Relative dispersion of intravascular transit times during isolated human limb perfusions for recurrent melanoma

Roberts, MS, Wu, ZY, Rivory, LP, Smithers, BM, Egerton, WS and Weiss, M (1997). Relative dispersion of intravascular transit times during isolated human limb perfusions for recurrent melanoma. British Journal of Clinical Pharmacology, 44 (4), 347-351. doi: 10.1046/j.1365-2125.1997.t01-1-00593.x

Relative dispersion of intravascular transit times during isolated human limb perfusions for recurrent melanoma

1997

Journal Article

The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft

Wu, Z. Y., Smithers, B. M., Parsons, P. G. and Roberts, M. S. (1997). The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft. British Journal of Cancer, 75 (8), 1160-1166. doi: 10.1038/bjc.1997.200

The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft

1997

Journal Article

Isolated limb perfusion with melphalan for human melanoma xenografts in the hindlimb of nude rats: A surviving animal model

Wu, ZY, Roberts, MS, Parsons, PG and Smithers, BM (1997). Isolated limb perfusion with melphalan for human melanoma xenografts in the hindlimb of nude rats: A surviving animal model. Melanoma Research, 7 (1), 19-26. doi: 10.1097/00008390-199702000-00004

Isolated limb perfusion with melphalan for human melanoma xenografts in the hindlimb of nude rats: A surviving animal model

Funding

Current funding

  • 2024 - 2025
    Optimising the Diagnosis and Management of Unilateral Primary Aldosteronism (MSH SERTA Grant led by Metro South HHS)
    Metro South Hospital and Health Service
    Open grant
  • 2023 - 2026
    iCare - An interactive online portal to improve health and wellbeing for people living with complex cancers, and their informal carers: a Phase II randomised controlled trial (Ex led Deakin MRFF CTA)
    Deakin University
    Open grant
  • 2021 - 2026
    AGITG TOP GEAR: A randomised phase II/III trial of preoperative chemoradiotherapy versus preoperative chemotherapy for resectable gastric cancer (CTCS: led by USyd)
    University of Sydney
    Open grant
  • 2019 - 2026
    A Randomised Phase II Trial of Adjuvant Avelumab in Patients with Early Stage Merkel Cell Carcinoma
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2019 - 2025
    Melanoma Margins Trial II - A Phase III, Multi-centre Randomised Controlled Trial Investigating 1cm v 2cm Wide Surgical Excision Margins.. (NHMRC Project Grant led by the University of Melbourne).
    University of Melbourne
    Open grant

Past funding

  • 2021 - 2024
    Advanced technological approach to predicting survival in patients diagnosed with locally invasive cutaneous melanoma
    Cancer Council Queensland
    Open grant
  • 2021 - 2024
    Establishing Australia's First Familial Melanoma Clinic (MSH RSS SERTA Program Grant led by Metro South Hospital and Health Service)
    Metro South Hospital and Health Service
    Open grant
  • 2020 - 2021
    Cancer Evolution Biobank
    PA Research Foundation
    Open grant
  • 2017 - 2019
    Predictors of mortality in thin melanomas
    Cancer Council Queensland
    Open grant
  • 2013 - 2015
    To identify and assess markers of prognosis, response and resistance to therapy in patients with Stage III metastatic melanoma
    Cancer Bequest Fund
    Open grant
  • 2011
    DOCetaxel with or without radiation Therapy for resectable Oesophageal adenocarcinoma based on early PET Response to induction chemotherapy (DOCTOR)
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Effects of nevogenesis susceptibility genes and phenotypic correlation with dermoscopic characteristics of nevi
    NHMRC Project Grant
    Open grant
  • 2010 - 2014
    Comparison of pre- and perioperative immunonutrition in patients undergoing surgical resection of oesophageal cancer (NHMRC Project Grant administered by the University of Adelaide)
    University of Adelaide
    Open grant
  • 2001 - 2002
    The epidemiology of oesophageal cancer: Risk and molecular markers
    Queensland Cancer Fund
    Open grant
  • 2000
    The role of TAP and MHC class I expression in the response to melanoma immunotherapy using autologous dendritic cells
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 1999 - 2000
    A phase II clinical trial in patients with metastatic melanoma comparing autologous dendritic cells pulsed with autologous tumour peptides and melanoma associated peptides linked to the endoplasmic re
    Queensland Cancer Fund
    Open grant
  • 1998
    A Phase I/II Clinical Trial to Test Tumour Vaccines Comprising with Protein or Autologous Tumour Antigen Autologous Dandritic Cells Generated in a Closed Bag System Pulsed
    Mayne Bequest Fund
    Open grant
  • 1998
    Isolated limb infusion of melphalan and microdialysis technique in treatment of recurrent malignant melanoma
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 1998 - 2000
    Treatment of Recurrent Malignant Melanoma by Limb Infusion of Cytotoxic Drugs and Other Techniques
    NHMRC Project Grant
    Open grant
  • 1997 - 1998
    Pharmacokinetics of tumour necrosis factor (TNF) in isolated rat hindlimb perfusions and infusions related to melanoma therapy
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 1996 - 1997
    Targeting and monitoring drug delivery in specific tissues using iontophoresis and microdialysis
    Quality Funds Round 3
    Open grant
  • 1995 - 1997
    Pharmacokinetics of melphalan in isolated limb perfusion and infusion
    Queensland Cancer Fund
    Open grant

Supervision

Availability

Professor Mark Smithers is:
Not available for supervision

Supervision history

Current supervision

  • Master Philosophy

    Assessment of the impact of treating service characteristics on surgical and oncological outcomes for patients with Retroperitoneal and Inguinal Sarcomas in Queensland

    Principal Advisor

    Other advisors: Professor Andrew Barbour

  • Doctor Philosophy

    New tools for the multi-modal evaluation of pancreatic cancer and its precursor neoplasms.

    Associate Advisor

    Other advisors: Dr David Cavallucci

  • Master Philosophy

    Factors Influencing Anastomotic Complications after Oesophagectomy

    Associate Advisor

Completed supervision

Media

Enquiries

Contact Professor Mark Smithers directly for media enquiries about:

  • Advanced endoscopic surgery
  • Cancer surgery
  • Endoscopic surgery
  • General surgery
  • Melanoma
  • Surgery - cancer
  • Surgery - oesophageal, gastric cancer
  • Surgery - upper GI
  • Upper GI surgery

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