Overview
Background
Dr Chris McMillan is a virologist who researches novel vaccine designs and delivery for viruses, including Polio, seasonal influenza, flaviviruses such as Dengue virus, as well as novel and emerging viruses such as SARS-CoV-2 and highly-pathogenic avian influenza.
His work uses a range of vaccine modalities, including recombinant proteins, virus-like particles, and more recently nucleic acid vaccines (DNA and mRNA).
To maximise vaccine efficacy, his research explores delivery of these vaccines using a high-density microarray patch delivery platform, which results in targeted vaccine delivery to the immune-rich layers of the skin. Recent work involves delivery of nucleic acid vaccines against SARS-CoV-2 and Influenza via the microarray patch system to create a potent, agile vaccine platform system to aid in Australia’s preparedness for future pandemics.
He was awarded an Advance Queensland Industry Research Fellowship in 2021.
Availability
- Dr Chris McMillan is:
- Available for supervision
Qualifications
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Chris McMillan’s works on UQ eSpace
2021
Journal Article
Adjuvant selection for influenza and RSV prefusion subunit vaccines
Isaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel and Chappell, Keith J. (2021). Adjuvant selection for influenza and RSV prefusion subunit vaccines. Vaccines, 9 (2) 71, 1-14. doi: 10.3390/vaccines9020071
2021
Journal Article
A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19
Idris, Adi, Davis, Alicia, Supramaniam, Aroon, Acharya, Dhruba, Kelly, Gabrielle, Tayyar, Yaman, West, Nic, Zhang, Ping, McMillan, Christopher L.D., Soemardy, Citradewi, Ray, Roslyn, O'Meally, Denis, Scott, Tristan A., McMillan, Nigel A.J. and Morris, Kevin V. (2021). A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19. Molecular Therapy, 29 (7), 2219-2226. doi: 10.1016/j.ymthe.2021.05.004
2021
Journal Article
The next generation of influenza vaccines: towards a universal solution
McMillan, Christopher L. D., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2021). The next generation of influenza vaccines: towards a universal solution. Vaccines, 9 (1) 26, 1-20. doi: 10.3390/vaccines9010026
2020
Journal Article
A novel purification procedure for active recombinant human DPP4 and the inability of DPP4 to bind SARS-CoV-2
Xi, Cecy R., Di Fazio, Arianna, Nadvi, Naveed Ahmed, Patel, Karishma, Xiang, Michelle Sui Wen, Zhang, Hui Emma, Deshpande, Chandrika, Low, Jason K K, Wang, Xiaonan Trixie, Chen, Yiqian, McMillan, Christopher L. D., Isaacs, Ariel, Osborne, Brenna, Vieira de Ribeiro, Ana Júlia, McCaughan, Geoffrey W., Mackay, Joel P., Church, W Bret and Gorrell, Mark D. (2020). A novel purification procedure for active recombinant human DPP4 and the inability of DPP4 to bind SARS-CoV-2. Molecules , 25 (22) 5392, 1-16. doi: 10.3390/molecules25225392
2019
Other Outputs
Rational design of a recombinant subunit influenza vaccine
McMillan, Christopher (2019). Rational design of a recombinant subunit influenza vaccine. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2019.923
2019
Journal Article
Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon
Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522
Funding
Current funding
Supervision
Availability
- Dr Chris McMillan is:
- Available for supervision
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Media
Enquiries
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