Overview
Availability
- Dr Jennifer Smith is:
- Available for supervision
Qualifications
- Masters (Research) of Molecular Biology, The University of Queensland
- Doctor of Philosophy of Immunology, The University of Queensland
Works
Search Professor Jennifer Smith’s works on UQ eSpace
2025
Journal Article
Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas
Quandt, Zoe, Young, Arabella, Barlow, Graham Larson, Smith, Jennifer A, Kusmartseva, Irina, Dong, Shen, Shapiro, Melanie R, Kang, Jee Hye, Felton, Jamie L, Nguyen, Vinh Q, Szot, Greg, Hassoun, Assad A, Perdigoto, Ana Luisa, Herold, Kevan C, Nolan, Garry, Bollyky, Paul L, Brusko, Todd M, Nakayama, Maki, Cooper, Stewart and Anderson, Mark S (2025). Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas. Journal for immunotherapy of cancer, 13 (8) e011818, 1-9. doi: 10.1136/jitc-2025-011818
2024
Journal Article
Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones
Smith, Jennifer A., Yuen, Benjamin T. K., Purtha, Whitney, Balolong, Jared M., Phipps, Jonah D., Crawford, Frances, Bluestone, Jeffrey A., Kappler, John W. and Anderson, Mark S. (2024). Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Proceedings of the National Academy of Sciences of the United States of America, 121 (20) e2320268121, 1-10. doi: 10.1073/pnas.2320268121
2024
Journal Article
Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model
Yin, Mianmian, Smith, Jennifer A, Chou, Marissa, Chan, Jackie, Jittayasothorn, Yingyos, Gould, Douglas B, Caspi, Rachel R, Anderson, Mark S and DeFranco, Anthony L (2024). Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America, 121 (5) e2311487121, 1-12. doi: 10.1073/pnas.2311487121
2022
Journal Article
Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
VanDyke, Derek, Iglesias, Marcos, Tomala, Jakub, Young, Arabella, Smith, Jennifer, Perry, Joseph A., Gebara, Edward, Cross, Amy R., Cheung, Laurene S., Dykema, Arbor G., Orcutt-Jahns, Brian T., Henclova, Tereza, Golias, Jaroslav, Balolong, Jared, Tomasovic, Luke M., Funda, David, Meyer, Aaron S., Pardoll, Drew M., Hester, Joanna, Issa, Fadi, Hunter, Christopher A., Anderson, Mark S., Bluestone, Jeffrey A., Raimondi, Giorgio and Spangler, Jamie B. (2022). Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Reports, 41 (3) 111478, 111478. doi: 10.1016/j.celrep.2022.111478
2021
Journal Article
A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance
Warshauer, Jeremy T, Belk, Julia A, Chan, Alice Y, Wang, Jiaxi, Gupta, Alexander R, Shi, Quanming, Skartsis, Nikolaos, Peng, Yani, Phipps, Jonah D, Acenas, Dante, Smith, Jennifer A, Tamaki, Stanley J, Tang, Qizhi, Gardner, James M, Satpathy, Ansuman T and Anderson, Mark S (2021). A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance. The Journal of Experimental Medicine, 218 (8) e20210759, 1-18. doi: 10.1084/jem.20210759
2021
Journal Article
Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
Hendley, Audrey M, Rao, Arjun A, Leonhardt, Laura, Ashe, Sudipta, Smith, Jennifer A, Giacometti, Simone, Peng, Xianlu L, Jiang, Honglin, Berrios, David I, Pawlak, Mathias, Li, Lucia Y, Lee, Jonghyun, Collisson, Eric A, Anderson, Mark S, Fragiadakis, Gabriela K, Yeh, Jen Jen, Ye, Chun Jimmie, Kim, Grace E, Weaver, Valerie M and Hebrok, Matthias (2021). Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. eLife, 10 e67776, 1-29. doi: 10.7554/eLife.67776
2020
Journal Article
Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis
Lee, James C., Mehdizadeh, Sadaf, Smith, Jennifer, Young, Arabella, Mufazalov, Ilgiz A., Mowery, Cody T., Daud, Adil and Bluestone, Jeffrey A. (2020). Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis. Science Immunology, 5 (52) eaba0759, 1-14. doi: 10.1126/sciimmunol.aba0759
2020
Journal Article
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
Whitman, Jeffrey D., Hiatt, Joseph, Mowery, Cody T., Shy, Brian R., Yu, Ruby, Yamamoto, Tori N., Rathore, Ujjwal, Goldgof, Gregory M., Whitty, Caroline, Woo, Jonathan M., Gallman, Antonia E., Miller, Tyler E., Levine, Andrew G., Nguyen, David N., Bapat, Sagar P., Balcerek, Joanna, Bylsma, Sophia A., Lyons, Ana M., Li, Stacy, Wong, Allison Wai-yi, Gillis-Buck, Eva Mae, Steinhart, Zachary B., Lee, Youjin, Apathy, Ryan, Lipke, Mitchell J., Smith, Jennifer Anne, Zheng, Tina, Boothby, Ian C., Isaza, Erin ... Marson, Alexander (2020). Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nature Biotechnology, 38 (10), 1174-1183. doi: 10.1038/s41587-020-0659-0
2019
Journal Article
Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage
Tuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0
2018
Journal Article
Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer
Bridge, Jennifer A., Lee, James C., Daud, Adil, Wells, James W. and Bluestone, Jeffrey A. (2018). Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer. Frontiers in Medicine, 5 (DEC) 351, 351. doi: 10.3389/fmed.2018.00351
2017
Journal Article
CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin
Overgaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R
2017
Journal Article
Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipients
Burke, Michael Thomas, Sambira Nahum, Lauren C., Isbel, Nicole M., Carroll, Robert P., Soyer, Hans Peter, Francis, Ross, Bridge, Jennifer Anne, Hawley, Carmel, Oliver, Kimberly, Staatz, Christine E. and Wells, James William (2017). Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipients. Transplantation Direct, 3 (7), e171. doi: 10.1097/TXD.0000000000000694
2017
Other Outputs
Uncovering novel regulators of CD8+ T-cell function in the skin
Bridge, Jennifer Anne (2017). Uncovering novel regulators of CD8+ T-cell function in the skin. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2017.812
2016
Conference Publication
Effects of immunosuppression and sun exposure on immune cell populations in skin and blood of kidney transplant recipients
Burke, M., Nahum, L., Isbel, N., Carroll, R., Soyer, H., Francis, R., Bridge, J., Staatz, C. and Wells, J. (2016). Effects of immunosuppression and sun exposure on immune cell populations in skin and blood of kidney transplant recipients. American Transplant Congress, Boston, MA USA, 11-15 June 2016. Hoboken, NJ USA: Wiley-Blackwell Publishing.
2016
Journal Article
Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection
Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418
2016
Journal Article
MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland
Wronski, A., Sandhu, G. K., Milevskiy, M. J., Brewster, B. L., Bridge, J. A., Shewan, A. M., Edwards, S. L., French, J. D. and Brown, M. A. (2016). MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland. Oncogenesis, 5 (4) e218, e218.1-e218.9. doi: 10.1038/oncsis.2016.27
2016
Conference Publication
CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin
Cruz, Gonzalez J. L., Overgaard, N. H., Bridge, J. A., Jung, J. -W, He, J., Nel, H. J., Watson, K., Frazer, I. H., La Gruta, N. L., Steptoe, R. J. and Wells, J. W. (2016). CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
2016
Conference Publication
Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions
Steptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.
2016
Conference Publication
Novel regulators of CD8(+) T-cell functions in the skin
Bridge, J. A., Overgaard, N. H., Cruz, J. L. G., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Novel regulators of CD8(+) T-cell functions in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-16 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
2016
Conference Publication
Uncovering novel regulators of CD8(+) T-cell functions in the skin
Bridge, J. A., Overgaard, N. H., Cruz, J. L., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Uncovering novel regulators of CD8(+) T-cell functions in the skin. Asia-Pacific Combined Dermatology Research Conference, Noosa, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/ajd.12584
Funding
Current funding
Supervision
Availability
- Dr Jennifer Smith is:
- Available for supervision
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Media
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