Overview
Background
Biography
Senior Lecturer Dr Ramon Ganigué leads a research program on microbial biotechnologies for sustainable manufacturing, addressing critical challenges such as climate change and circular resource management for the benefit of people and planet.
He obtained his PhD in Environmental Engineering from the University of Girona, Spain. Prior to joining The University of Queensland (UQ), Ramon held academic and research positions across Europe and Australia, including Assistant Professor (2017–2022) and Associate Professor (2022–2026) in the Department of Biotechnology at Ghent University, Belgium, alongside postdoctoral appointments at Ghent University, the University of Girona, and UQ.
He has published over 100 peer‑reviewed articles and established extensive international collaborations spanning Europe, Australia, China, and North America. Ramon has led multiple large-scale, multi-partner research projects and, over the past five years, has secured approximately AUD 10 million in competitive European funding to support his team’s activities. In 2024, he was appointed Associate Editor of Frontiers in Bioprocess Engineering.
Research
Vision: To harness the diversity and functionality of microbial systems to enable sustainable, circular manufacturing processes that decouple production from fossil resources and support the transition to a net-zero bioeconomy.
Mission: To engineer robust, scalable microbial bioprocesses that convert complex, non-refined feedstocks into high-value products for the benefit of people and planet. His team integrates microbial physiology, community engineering, and process design to unlock the potential of non-model microorganisms and microbiomes, while developing intensified and industrially relevant bioprocess platforms.
Dr Ramon Ganigué’s research lies at the intersection of microbial biotechnology, chemical engineering, and sustainability, with a focus on engineering microbial bioprocesses for sustainable production systems. His team applies an integrated toolbox spanning microbial physiology, community engineering, metabolic and process modelling, and bioprocess intensification to develop next-generation biotechnologies.
Central to this approach is a deep understanding of microbial physiology and metabolism. The research places particular emphasis on non-model microorganisms, including anaerobes, extremophiles, and complex microbiomes, which offer unique and underexploited capabilities for sustainable bioproduction. These systems are leveraged to convert non-refined and complex feedstocks into value-added products, such as biochemicals, biofuels, bioplastics, and alternative proteins.
A key focus of the program is addressing the operational and engineering challenges that limit industrial deployment. This includes the development of continuous, intensified, and non-axenic bioprocesses, as well as innovative reactor configurations designed to enhance robustness, efficiency, and scalability. Through this integrated approach, the research aims to bridge the gap between fundamental microbiology and industrial application, enabling practical and scalable solutions for sustainable manufacturing.
While sustainable biomanufacturing remains a core focus, the group actively explores the application of its microbial biotechnology toolbox to other systems and challenges aligned with sustainability goals for people and planet.
Teaching & learning contributions
Ramon is an experienced educator contributing across undergraduate and postgraduate programs. He currently lectures in key courses including Principles of Biomedical and Bioprocess Engineering (BIOE1001), Environmental Systems (ENVE2501), and the capstone Process Engineering Design Project (CHEE4001). He is also co-editor of the 2024 IWA Scientific Book Resource Recovery from Water: Principles and Application, and has contributed to MOOCs on resource recovery from wastewater and carbon capture and utilisation technologies.
Availability
- Dr Ramon Ganigue is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Environmental Sciences, Universitat de Girona
- Masters (Research) of Environmental Biotechnology, Universitat de Girona
- Doctor of Philosophy, Universitat de Girona
Works
Search Professor Ramon Ganigue’s works on UQ eSpace
2025
Journal Article
Large-sized aerobic granular biofilm: stable biotechnology to improve nitrogen removal and reduce sludge yield
Ma, Haibo, Chen, Sihao, Lv, Linhuan, Ye, Zhou, Yang, Jiaqi, Wang, Binbin, Zou, Jinte, Li, Jun and Ganigue, Ramon (2025). Large-sized aerobic granular biofilm: stable biotechnology to improve nitrogen removal and reduce sludge yield. Bioresource Technology, 429 132543, 1-10. doi: 10.1016/j.biortech.2025.132543
2025
Journal Article
Characterization of solvents and extractants for selective recovery of n-caproic acid
Fernandez-Blancoa, Carla, Sabbeb, Kevin, Veigaa, Maria C., Kennesa, Christian and Ganigue, Ramon (2025). Characterization of solvents and extractants for selective recovery of n-caproic acid. Separation and Purification Technology, 361 131411, 1-9. doi: 10.1016/j.seppur.2025.131411
2025
Journal Article
Implementation of a Clostridium luticellarii genome-scale model for upgrading syngas fermentations
Scott, William T., Rockx, Siemen, Marien, Quinten, Regueira, Alberte, Candry, Pieter, Ganigue, Ramon, Koehorst, Jasper J. and Schaap, Peter J. (2025). Implementation of a Clostridium luticellarii genome-scale model for upgrading syngas fermentations. Computational and Structural Biotechnology Journal, 27, 649-660. doi: 10.1016/j.csbj.2025.01.013
2024
Journal Article
Editorial: Microbial biorefineries for a more sustainable, circular economy
Sakarika, Myrsini, Matassa, Silvio, Carvajal-Arroyo, Jose M. and Ganigue, Ramon (2024). Editorial: Microbial biorefineries for a more sustainable, circular economy. Frontiers in Bioengineering and Biotechnology, 12 1512756. doi: 10.3389/fbioe.2024.1512756
2024
Journal Article
Isobutyric and n-butyric acid production from H2 and CO2 by Clostridium luticellarii in a hollow fiber membrane biofilm reactor: Reactor operation and process modelling
Marien, Quinten, Flores-Alsina, Xavier, Aslam, Umair, Gernaey, Krist V., Regueira, Alberte and Ganigue, Ramon (2024). Isobutyric and n-butyric acid production from H2 and CO2 by Clostridium luticellarii in a hollow fiber membrane biofilm reactor: Reactor operation and process modelling. Chemical Engineering Journal, 495 153216, 1-13. doi: 10.1016/j.cej.2024.153216
2024
Journal Article
Comprehensive comparative study on n-caproate production by Clostridium kluyveri: batch vs. continuous operation modes
Fernandez-Blanco, Carla, Pereira, Alexandra, Veiga, Maria C., Kennes, Christian and Ganigue, Ramon (2024). Comprehensive comparative study on n-caproate production by Clostridium kluyveri: batch vs. continuous operation modes. Bioresource Technology, 408 131138, 1-9. doi: 10.1016/j.biortech.2024.131138
2024
Journal Article
Editorial: Microbial chain elongation-carbon recovering biorefineries for the circular economy
Strik, David P. B. T. B. and Ganigue, Ramon (2024). Editorial: Microbial chain elongation-carbon recovering biorefineries for the circular economy. Frontiers in Bioengineering and Biotechnology, 12 1448975. doi: 10.3389/fbioe.2024.1448975
2024
Journal Article
Conditions for successful nitrogen removal from source-separated urine by partial nitritation/anammox
Faust, Valentin, Markus, Philipp, Schielke-Jenni, Sarina, Timmer, Marijn J., De Paepe, Jolien, Ganigue, Ramon, Vlaeminck, Siegfried E. and Udert, Kai M. (2024). Conditions for successful nitrogen removal from source-separated urine by partial nitritation/anammox. PLoS Water, 3 (5) e0000235, 1-23. doi: 10.1371/journal.pwat.0000235
2024
Journal Article
Resource-efficient nitrogen removal from source-separated urine with partial nitritation/anammox in a membrane-aerated biofilm reactor
Timmer, Marijn J., De Paepe, Jolien, Van Winckel, Tim, Spiller, Marc, Spacova, Irina, De Paepe, Kim, Pintelon, Isabel, Lebeer, Sarah, De Vos, Winnok H., Lasseur, Christophe, Ganigue, Ramon, Udert, Kai M. and Vlaeminck, Siegfried E. (2024). Resource-efficient nitrogen removal from source-separated urine with partial nitritation/anammox in a membrane-aerated biofilm reactor. ACS ES&T Engineering, 4 (7), 1609-1621. doi: 10.1021/acsestengg.4c00058
2024
Journal Article
Radiotolerance of N-cycle bacteria and their transcriptomic response to low-dose space-analogue ionizing irradiation
Verbeelen, Tom, Fernandez, Celia Alvarez, Nguyen, Thanh Huy, Gupta, Surya, Leroy, Baptiste, Wattiez, Ruddy, Vlaeminck, Siegfried E., Leys, Natalie, Ganigue, Ramon and Mastroleo, Felice (2024). Radiotolerance of N-cycle bacteria and their transcriptomic response to low-dose space-analogue ionizing irradiation. iScience, 27 (5) 109596, 1-20. doi: 10.1016/j.isci.2024.109596
2024
Journal Article
Why do lactic acid bacteria thrive in chain elongation microbiomes?
Ulcar, Barbara, Regueira, Alberte, Podojstersek, Maja, Boon, Nico and Ganigue, Ramon (2024). Why do lactic acid bacteria thrive in chain elongation microbiomes?. Frontiers in Bioengineering and Biotechnology, 11 1291007, 1-17. doi: 10.3389/fbioe.2023.1291007
2024
Journal Article
Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity
Verbeelen, Tom, Fernandez, Celia Alvarez, Nguyen, Thanh Huy, Gupta, Surya, Aarts, Raf, Tabury, Kevin, Leroy, Baptiste, Wattiez, Ruddy, Vlaeminck, Siegfried E., Leys, Natalie, Ganigue, Ramon and Mastroleo, Felice (2024). Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity. npj Microgravity, 10 (1) 3, 1-19. doi: 10.1038/s41526-024-00345-z
2024
Journal Article
Steerable isobutyric and butyric acid production from CO2 and H2 by Clostridium luticellarii
Marien, Quinten, Regueira, Alberte and Ganigue, Ramon (2024). Steerable isobutyric and butyric acid production from CO2 and H2 by Clostridium luticellarii. Microbial Biotechnology, 17 (1) e14321, 1-16. doi: 10.1111/1751-7915.14321
2023
Journal Article
Influence of pH on urine nitrification: Community shifts of ammonia-oxidizing bacteria and inhibition of nitrite-oxidizing bacteria
Faust, Valentin, Vlaeminck, Siegfried E., Ganigue, Ramon and Udert, Kai M. (2023). Influence of pH on urine nitrification: Community shifts of ammonia-oxidizing bacteria and inhibition of nitrite-oxidizing bacteria. ACS ES&T Engineering, 4 (2), 342-353. doi: 10.1021/acsestengg.3c00320
2023
Journal Article
Trophic interactions shape the spatial organization of medium-chain carboxylic acid producing granular biofilm communities
Candry, Pieter, Chadwick, Grayson L., Caravajal-Arroyo, Jose Maria, Lacoere, Tim, Winkler, Mari-Karoliina Henriikka, Ganigue, Ramon, Orphan, Victoria J. and Rabaey, Korneel (2023). Trophic interactions shape the spatial organization of medium-chain carboxylic acid producing granular biofilm communities. ISME Journa, 17 (11), 2014-2022. doi: 10.1038/s41396-023-01508-8
2023
Journal Article
Optimizing control strategies for urine nitrification: narrow pH control band enhances process stability and reduces nitrous oxide emissions
Faust, Valentin, Boon, Nico, Ganigue, Ramon, Vlaeminck, Siegfried E. and Udert, Kai M. (2023). Optimizing control strategies for urine nitrification: narrow pH control band enhances process stability and reduces nitrous oxide emissions. Frontiers in Environmental Science, 11 1275152, 1-14. doi: 10.3389/fenvs.2023.1275152
2023
Journal Article
RNA extraction protocol from low-biomass bacterial Nitrosomonas europaea and Nitrobacter winogradskyi cultures for whole transcriptome studies
Verbeelen, Tom, Van Houdt, Rob, Leys, Natalie, Ganigue, Ramon and Mastroleo, Felice (2023). RNA extraction protocol from low-biomass bacterial Nitrosomonas europaea and Nitrobacter winogradskyi cultures for whole transcriptome studies. STAR Protocols, 4 (3) 102358, 1-9. doi: 10.1016/j.xpro.2023.102358
2023
Journal Article
Predicting the performance of chain elongating microbiomes through flow cytometric fingerprinting
Sabbe, Kevin, D'Haen, Liese, Boon, Nico and Ganigu, Ramon (2023). Predicting the performance of chain elongating microbiomes through flow cytometric fingerprinting. Water Research, 243 120323, 1-11. doi: 10.1016/j.watres.2023.120323
2023
Journal Article
Plant and microbial science and technology as cornerstones to Bioregenerative Life Support Systems in space
De Micco, Veronica, Amitrano, Chiara, Mastroleo, Felice, Aronne, Giovanna, Battistelli, Alberto, Carnero-Diaz, Eugenie, De Pascale, Stefania, Detrell, Gisela, Dussap, Claude-Gilles, Ganigue, Ramon, Jakobsen, Oyvind Mejdell, Poulet, Lucie, Van Houdt, Rob, Verseux, Cyprien, Vlaeminck, Siegfried E., Willaert, Ronnie and Leys, Natalie (2023). Plant and microbial science and technology as cornerstones to Bioregenerative Life Support Systems in space. npj Microgravity, 9 (1) 69, 1-12. doi: 10.1038/s41526-023-00317-9
2023
Journal Article
Methylotrophs: from C1 compounds to food (vol 75, 102685,2022)
Sakarika, Myrsini, Ganigue, Ramon and Rabaey, Korneel (2023). Methylotrophs: from C1 compounds to food (vol 75, 102685,2022). Current Opinion in Biotechnology, 82 102964. doi: 10.1016/j.copbio.2023.102964
Funding
Past funding
Supervision
Availability
- Dr Ramon Ganigue is:
- Available for supervision
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Available projects
-
Engineering scalable single cell oil production for sustainable manufacturing of oleochemicals
Single cell oils (SCO) production provides a powerful route to generate sustainable oils and oleochemicals from renewable and non-refined feedstocks, decoupling lipid supply from conventional agriculture.
Harnessing the metabolic capacity of oleaginous microorganisms, SCO systems convert diverse carbon sources into energy-dense triacylglycerols, offering high productivity and flexibility compared to traditional oil crops.
However, maximising lipid yields while maintaining process efficiency and scalability remains a central challenge, requiring an integrated understanding of microbial metabolism and bioprocess operation.
This PhD project will address these challenges by developing advanced SCO production strategies that optimise carbon partitioning, process performance, and industrial feasibility.
-
Engineering scalable microbial protein production from sustainable feedstocks
Microbial protein (MP) production offers a promising route to decouple protein supply from conventional agriculture, enabling sustainable, high-efficiency conversion of renewable feedstocks into nutritious biomass.
Leveraging the metabolic versatility of microorganisms, MP systems can valorise low-value and non-refined resources into high-quality protein, contributing to circular and low-carbon manufacturing.
However, achieving both high productivity and desirable protein quality remains a key challenge, requiring an integrated approach that combines microbial physiology, process engineering, and bioprocess intensification.
This PhD project will address these challenges by developing next-generation MP production strategies that balance growth performance, product quality, and process scalability for industrial deployment.
Media
Enquiries
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