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Dr Philip Sharpe
Dr

Philip Sharpe

Email: 
Phone: 
+61 7 336 59149

Overview

Background

My research interests are in the field of Chemistry education, particularly how students learn in the chemistry laboratory.

I teach biological inorganic chemistry at a second and Masters level, as well as a broad range of topics in first year chemistry. I also teach the ethics of chemistry in second year.

Availability

Dr Philip Sharpe is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Law, The University of Queensland
  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland
  • Member, Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Chemistry education

    I am interested in the ways that students learn to communicate Chemistry and how the barriers to effective learning in Chemistry can be reduced. I have a particular interest in learning in the laboratory setting.

Works

Search Professor Philip Sharpe’s works on UQ eSpace

48 works between 1996 and 2021

1 - 20 of 48 works

Featured

2014

Journal Article

Chemistry for the masses

Sharpe, Philip C. and Blanchfield, Joanne T. (2014). Chemistry for the masses. International Journal of Innovation in Science and Mathematics Education, 22 (4), 33-47.

Chemistry for the masses

Featured

2011

Journal Article

Synthetic and natural products as iron chelators

Sharpe, Philip C., Richardson, Des R., Kalinowski, Danuta S. and Bernhardt, Paul V. (2011). Synthetic and natural products as iron chelators. Current Topics in Medicinal Chemistry, 11 (5), 591-607. doi: 10.2174/156802611794785163

Synthetic and natural products as iron chelators

2021

Conference Publication

Online, virtual, and adaptive learning environments: improving the journey through large first year chemistry courses

Kartsonaki, Effie, Lawrie, Gwen, Sharpe, Philip and Bailey, Chantal (2021). Online, virtual, and adaptive learning environments: improving the journey through large first year chemistry courses. Australian Conference on Science and Mathematics Education, Brisbane, QLD Australia, 28-30 September 2015.

Online, virtual, and adaptive learning environments: improving the journey through large first year chemistry courses

2020

Book

Chemistry for Queensland Units 1 & 2 Student Workbook

Adriaans, Kate and Sharpe, Philip (2020). Chemistry for Queensland Units 1 & 2 Student Workbook. Oxford, United Kingdom: Oxford University Press.

Chemistry for Queensland Units 1 & 2 Student Workbook

2019

Book

Chemistry for Queensland units 3 & 4 student workbook

Drenen, Carolyn and Sharpe, Philip (2019). Chemistry for Queensland units 3 & 4 student workbook. Docklands, VIC, Australia: Oxford University Press.

Chemistry for Queensland units 3 & 4 student workbook

2019

Book

Chemistry for Queensland Units 3 & 4

Kuipers, Krystle, Devlin, Paul, Braebec, Martin, Sharpe, Philip and Bloomfield, Carrie (2019). Chemistry for Queensland Units 3 & 4. Oxford, United Kingdom: Oxford University Press.

Chemistry for Queensland Units 3 & 4

2018

Book

Chemistry for Queensland Units 1 & 2

Kuipers, Krystle, Devlin, Paul, Keillor, Paul, Sharpe, Philip, Bloomfield, Carrie and Silvester, Helen (2018). Chemistry for Queensland Units 1 & 2. Oxford, United Kingdom: Oxford University Press.

Chemistry for Queensland Units 1 & 2

2016

Journal Article

Novel mechanism of cytotoxicity for the selective selenosemicarbazone, 2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone (Ap44mSe): lysosomal membrane permeabilization

Al-Eisawi, Zaynab, Stefani, Christian, Jansson, Patric J., Arvind, Akanksha, Sharpe, Philip C., Basha, Maram T., Iskander, George M., Kumar, Naresh, Kovacevic, Zaklina, Lane, Darius J. R., Sahni, Sumit, Bernhardt, Paul V., Richardson, Des R. and Kalinowski, Danuta S. (2016). Novel mechanism of cytotoxicity for the selective selenosemicarbazone, 2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone (Ap44mSe): lysosomal membrane permeabilization. Journal of Medicinal Chemistry, 59 (1), 294-312. doi: 10.1021/acs.jmedchem.5b01399

Novel mechanism of cytotoxicity for the selective selenosemicarbazone, 2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone (Ap44mSe): lysosomal membrane permeabilization

2014

Journal Article

Electrochemically mediated enantioselective reduction of chiral sulfoxides

Chen, Kuan I., Challinor, Victoria L., Kielmann, Linda, Sharpe, Philip C., De Voss, James J., Kappler, Ulrike, McEwan, Alastair G. and Bernhardt, Paul V. (2014). Electrochemically mediated enantioselective reduction of chiral sulfoxides. Journal of Biological Inorganic Chemistry, 20 (2), 395-402. doi: 10.1007/s00775-014-1215-5

Electrochemically mediated enantioselective reduction of chiral sulfoxides

2013

Journal Article

Planar array of corrugated tapered slot antennas for ultrawideband biomedical microwave imaging system

Mohammed, Beada'a J., Abbosh, Amin M. and Sharpe, Philip (2013). Planar array of corrugated tapered slot antennas for ultrawideband biomedical microwave imaging system. International Journal of RF and Microwave Computer-Aided Engineering, 23 (1), 59-66. doi: 10.1002/mmce.20651

Planar array of corrugated tapered slot antennas for ultrawideband biomedical microwave imaging system

2012

Journal Article

Novel second-generation Di-2-Pyridylketone Thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo

Lovejoy, David B., Sharp, Danae M., Seebacher, Nicole, Obeidy, Peyman, Prichard, Thomas, Stefani, Christian, Basha, Maram T., Sharpe, Philip C., Jansson, Patric J., Kalinowski, Danuta S., Bernhardt, Paul V. and Richardson, Des R. (2012). Novel second-generation Di-2-Pyridylketone Thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo. Journal of Medicinal Chemistry, 55 (16), 7230-7244. doi: 10.1021/jm300768u

Novel second-generation Di-2-Pyridylketone Thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo

2012

Journal Article

Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect

Quach, Patricia, Gutierrez, Elaine, Basha, Maram Talal, Kalinowski, Danuta S., Sharpe, Philip C., Lovejoy, David B., Bernhardt, Paul V., Jansson, Patric J. and Richardson, Des R. (2012). Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect. Molecular Pharmacology, 82 (1), 105-114. doi: 10.1124/mol.112.078964

Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect

2012

Conference Publication

Who's afraid of the chemistry lab?

Sharpe, Philip C. (2012). Who's afraid of the chemistry lab?. Australian Conference on Science and Mathematics Education 2012, Sydney, Australia, 26-28th September 2012. Sydney, Australia: The University of Sydney, UniServe Science.

Who's afraid of the chemistry lab?

2012

Conference Publication

Head phantom for testing microwave systems for head imaging

Mohammed, Beada’a, Abbosh, Amin, Henin, Bassem and Sharpe, Philip (2012). Head phantom for testing microwave systems for head imaging. 2012 Cairo International Biomedical Engineering Conference (CIBEC), Cairo, Egypt, 20 - 22 December 2012. Piscataway, NJ, United States: IEEE. doi: 10.1109/CIBEC.2012.6473320

Head phantom for testing microwave systems for head imaging

2011

Journal Article

Halogenated 2′-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: Relationship to intracellular redox activity

Stefani, Christian, Punnia-Moorthy, Gaya, Lovejoy, David B., Jansson, Patric J., Kalinowski, Danuta S., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2011). Halogenated 2′-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: Relationship to intracellular redox activity. Journal of Medicinal Chemistry, 54 (19), 6936-6948. doi: 10.1021/jm200924c

Halogenated 2′-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: Relationship to intracellular redox activity

2011

Journal Article

Heterogeneous breast phantom for ultra wideband microwave imaging

Abu Bakar, A, Abbosh, A, Sharpe, P, Bialkowski, ME and Wang, YF (2011). Heterogeneous breast phantom for ultra wideband microwave imaging. Microwave and Optical Technology Letters, 53 (7), 1595-1598. doi: 10.1002/mop.26046

Heterogeneous breast phantom for ultra wideband microwave imaging

2011

Journal Article

The medicinal chemistry of novel iron chelators for the treatment of cancer

Kovacevic, Zaklina, Kalinowski, Danuta S., Lovejoy, David B., Yu, Yu, Rahmanto, Yohan Suryo, Sharpe, Phillip C., Bernhardt, Paul V. and Richardson, Des R. (2011). The medicinal chemistry of novel iron chelators for the treatment of cancer. Current Topics in Medicinal Chemistry, 11 (5), 483-499. doi: 10.2174/156802611794785190

The medicinal chemistry of novel iron chelators for the treatment of cancer

2011

Journal Article

Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates

Singh, Yogendra, Sharpe, Philip C., Hoang, Huy N., Lucke, Andrew J., McDowall, Alasdair W., Bottomley, Stephen P. and Fairlie, David P. (2011). Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates. Chemistry: A European Journal, 17 (1), 151-160. doi: 10.1002/chem.201002500

Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates

2010

Journal Article

Novel thiosemicarbazones of the ApT and DpT Series and their copper complexes: Identification of pronounced redox activity and characterization of their antitumor activity

Jansson, Patric J., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2010). Novel thiosemicarbazones of the ApT and DpT Series and their copper complexes: Identification of pronounced redox activity and characterization of their antitumor activity. Journal of Medicinal Chemistry, 53 (15), 5759-5769. doi: 10.1021/jm100561b

Novel thiosemicarbazones of the ApT and DpT Series and their copper complexes: Identification of pronounced redox activity and characterization of their antitumor activity

2010

Conference Publication

Artificial breast phantom for microwave imaging modality

Abu Bakar, Aslina, Abbosh, Amin, Sharpe, Philip and Bialkowski, Marek (2010). Artificial breast phantom for microwave imaging modality. IEEE EMBS Conference on Biomedical Engineering and Sciences 2010, Kuala Lumpur, Malaysia, 30 November - 2 December 2010. United States: IEEE (Institute for Electrical and Electronic Engineers). doi: 10.1109/IECBES.2010.5742267

Artificial breast phantom for microwave imaging modality

Funding

Past funding

  • 2015 - 2016
    Online, virtual and adaptive learning environments: improving the journey through large first year chemistry courses
    Technology-Enhanced Learning Grants
    Open grant
  • 2005 - 2007
    Chemical Insights to Peptide Helix-Sheet-Nanofibre Equilibria
    ARC Discovery Projects
    Open grant

Supervision

Availability

Dr Philip Sharpe is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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communications@uq.edu.au