Overview
Background
Dr Brett Hughes graduated from the University of NSW with a Bachelor of Medical Science and Bachelor of Medicine and Surgery in 1997. He completed his postgraduate training in Canberra and Brisbane and was admitted as a Fellow of the Australian College of Physicians as a Specialist Medical Oncologist in 2005.
Dr Hughes is currently a Senior Staff Specialist Medical Oncologist at the RBWH and TPCH. He is also an Associate Professor at the University of Queensland since 2015. As the previous Clinical Director of Oncology (201-2017) and current Cancer Care Services Research lead at TPCH, Dr Hughes has established both an independent TPCH Oncology unit and continuing TPCH’s reputation as a lung cancer research centre of excellence.
Dr Hughes is an active senior member of the Thoracic Oncology Group Australasia (TOGA) and the Trans Tasman Radiation Oncology Group (TROG). He is also heavily involved in many pivotal multicentre trials of cancer therapy at both TPCH and RBWH with his principal research interests in Lung cancer, Head & Neck cancer, Mesothelioma, cutaneous SCC and Thyroid cancer. He has published over 100 peer review papers. Dr Hughes is also involved in undergraduate and post graduate teaching in his fields of research interest.
Availability
- Associate Professor Brett Hughes is:
- Available for supervision
Fields of research
Works
Search Professor Brett Hughes’s works on UQ eSpace
2014
Conference Publication
Single Agent Panitumumab in Patients With Incurable Cutaneous Squamous Cell Carcinoma: A Single-Center Phase 2 Study
Porceddu, S., Foote, M., McGrath, M., Guminski, A., Hughes, B., Meakin, J., Thomson, D., Thomson, D. and Simpson, F. (2014). Single Agent Panitumumab in Patients With Incurable Cutaneous Squamous Cell Carcinoma: A Single-Center Phase 2 Study. ELSEVIER SCIENCE INC. doi: 10.1016/j.ijrobp.2013.11.179
2013
Journal Article
Validated swallowing and nutrition guidelines for patients with head and neck cancer: Identification of high-risk patients for proactive gastrostomy
Brown, Teresa E., Spurgin, Ann-Louise, Ross, Lynda, Tripcony, Lee, Keller, Jacqui, Hughes, Brett G. M., Hodge, Rob, Walker, Quenten, Banks, Merrilyn, Kenny, Lizbeth Moira and Crombie, Jane (2013). Validated swallowing and nutrition guidelines for patients with head and neck cancer: Identification of high-risk patients for proactive gastrostomy. Head and Neck, 35 (10), 1385-1391. doi: 10.1002/hed.23146
2013
Journal Article
A phase II clinical trial of the vascular disrupting agent BNC105P as second line chemotherapy for advanced malignant pleural mesothelioma
Nowak, Anna K., Brown, Chris, Millward, Michael J., Creaney, Jenette, Byrne, Michael J., Hughes, Brett, Kremmidiotis, Gabriel, Bibby, David C., Leske, Annabell F., Mitchell, Paul L. R., Pavlakis, Nick, Boyer, Michael and Stockler, Martin R. (2013). A phase II clinical trial of the vascular disrupting agent BNC105P as second line chemotherapy for advanced malignant pleural mesothelioma. Lung Cancer, 81 (3), 422-427. doi: 10.1016/j.lungcan.2013.05.006
2013
Journal Article
Comment on 'The efficacy and toxicity of gemcitabine, carboplatin and bevacizumab in metastatic breast cancer'
Kitchen, D., O'Brien, M., Hughes, B., Gill, I., Rumbles, S., Ellis, P. and Stebbing, J. (2013). Comment on 'The efficacy and toxicity of gemcitabine, carboplatin and bevacizumab in metastatic breast cancer'. British Journal of Cancer, 109 (2), 526-528. doi: 10.1038/bjc.2013.279
2013
Journal Article
Other novel molecular targets in non-small cell lung cancer: it's not all about EGFR
Cruikshank, Ross and Hughes, Brett (2013). Other novel molecular targets in non-small cell lung cancer: it's not all about EGFR. Cancer Forum, 37 (2), 170-174.
2013
Journal Article
Decreased hospital stay and significant cost savings after routine use of prophylactic gastrostomy for high-risk patients with head and neck cancer receiving chemoradiotherapy at a tertiary cancer institution
Hughes, B. G. M., Jain, V. K., Brown, T., Spurgin, A. L., Hartnett, G., Keller, J., Tripcony, L., Appleyard, M. and Hodge, R. (2013). Decreased hospital stay and significant cost savings after routine use of prophylactic gastrostomy for high-risk patients with head and neck cancer receiving chemoradiotherapy at a tertiary cancer institution. Dysphagia, 28 (3). doi: 10.1007/s00455-013-9468-7
2013
Journal Article
Decreased hospital stay and significant cost savings after routine use of prophylactic gastrostomy for high-risk patients with head and neck cancer receiving chemoradiotherapy at a tertiary cancer institution
Hughes, Brett G. M., Jain, Vikram K., Brown, Teresa, Spurgin, Ann-Louise, Hartnett, Gemma, Keller, Jacqui, Tripcony, Lee, Appleyard, Mark and Hodge, Robert (2013). Decreased hospital stay and significant cost savings after routine use of prophylactic gastrostomy for high-risk patients with head and neck cancer receiving chemoradiotherapy at a tertiary cancer institution. Head and Neck, 35 (3), 436-442. doi: 10.1002/hed.22992
2013
Journal Article
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Savas, Peter, Hughes, Brett and Solomon, Benjamin (2013). Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer. Journal of Thoracic Disease, 5 (5), S579-S592. doi: 10.3978/j.issn.2072-1439.2013.08.52
2013
Conference Publication
Single agent panitumumab in patients with incurable cutaneous squamous cell carcinoma: A single centre phase II study
Foote, M., McGrath, M., Guminski, A., Hughes, B., Meakin, J., Thomson, D., Simpson, F. and Porceddu, S. (2013). Single agent panitumumab in patients with incurable cutaneous squamous cell carcinoma: A single centre phase II study. 17th ECCO / 38th ESMO / 32nd ESTRO European Cancer Congress on Reinforcing Multidisciplinarity, Amsterdam Netherlands, Sep 27-Oct 01, 2013. Oxford United Kingdom: Pergamon Press. doi: 10.1016/S0959-8049(13)70065-0
2012
Journal Article
Challenging the distal-to-proximal cannulation technique for administration of anticancer therapies: A prospective cohort study
Chan, Raymond Javan, Alexander, Alison, Bransdon, Maree, Webster, Joan, Hughes, Brett Gordon Maxwell, Brown, Leisa and Graham, Therese (2012). Challenging the distal-to-proximal cannulation technique for administration of anticancer therapies: A prospective cohort study. Cancer Nursing, 35 (5), E35-E40. doi: 10.1097/NCC.0b013e3182352916
2012
Conference Publication
Pulmonary Embolism in Medical Oncology Patients: Symptomatic Versus Incidental
Thaker, D. A., Blazak, J., Wyld, D., Steinke, K., Hughes, B. and Burge, M. (2012). Pulmonary Embolism in Medical Oncology Patients: Symptomatic Versus Incidental. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
The relationship between vitamin D and chemotherapy-induced toxicity-a pilot study
Kitchen, D., Hughes, B., Gill, I., O'Brien, M., Rumbles, S., Ellis, P., Harper, P., Stebbing, J. and Rohatgi, N. (2012). The relationship between vitamin D and chemotherapy-induced toxicity-a pilot study. British Journal of Cancer, 107 (1), 158-160. doi: 10.1038/bjc.2012.194
2012
Journal Article
Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib
Punnoose, Elizabeth A., Atwal, Siminder, Liu, Weiqun, Raja, Rajiv, Fine, Bernard M., Hughes, Brett G. M., Hicks, Rodney J., Hampton, Garret M., Amler, Lukas C., Pirzkall, Andrea and Lackner, Mark R. (2012). Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib. Clinical Cancer Research, 18 (8), 2391-2401. doi: 10.1158/1078-0432.CCR-11-3148
2012
Conference Publication
Safety of bevacizumab used in routine practice in patients with metastatic colorectal cancer
Dzienis, M., Malczewski, A., Goh, J., Hughes, B., Eastgate, M., Wyld, D. and Burge, M. (2012). Safety of bevacizumab used in routine practice in patients with metastatic colorectal cancer. Medical Oncology Group of Australia Incorporated Annual Scientific Meeting, Program and Abstracts: Targeting Cancer from Diagnosis to Cure & 5th Annual COGNO Annual Scientific Meeting, Brisbane, QLD Australia, 8-10 August 2012. Wiley-Blackwell Publishing.
2012
Journal Article
Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review
So, W. K. W., Chan, R. J., Chan, D. N. S., Hughes, B. G. M., Chair, S. Y., Choi, K. C. and Chan, C. W. H. (2012). Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review. European Journal of Cancer, 48 (15), 2391-2408. doi: 10.1016/j.ejca.2012.04.005
2011
Journal Article
Medical management of mesothelioma
Bowman, Rayleen, Relan, Vandana and Hughes, Brett (2011). Medical management of mesothelioma. Australian Prescriber, 34 (5), 144-147. doi: 10.18773/austprescr.2011.076
2011
Journal Article
Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib
Mileshkin, Linda, Hicks, Rodney J., Hughes, Brett G. M., Mitchell, Paul L. R., Charu, Veena, Gitlitz, Barbara J., Macfarlane, David, Solomon, Benjamin, Amler, Lukas C., Yu, Wei, Pirzkall, Andrea and Fine, Bernard M. (2011). Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib. Clinical Cancer Research, 17 (10), 3304-3315. doi: 10.1158/1078-0432.CCR-10-2763
2011
Journal Article
Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer
Tran, Khoi, Bigby, Kieron J., Hughes, Brett G., Lee, Lawrence and Allison, Roger (2011). Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer. Asia-Pacific Journal of Clinical Oncology, 7 (1), 11-14. doi: 10.1111/j.1743-7563.2010.01332.x
2011
Conference Publication
Challenging the distal-to-proximal technique in the administration of anti-cancer therapies: A prospective cohort study
Alexander, Alison, Chan, Raymond, Bransdon, Maree, Hughes, Brett, Brown, Leisa and Graham, Therese (2011). Challenging the distal-to-proximal technique in the administration of anti-cancer therapies: A prospective cohort study. The 20th annual RBWH Health Care Symposium: Personalised Health Care, Herston, Brisbane, QLD, Australia, 10-14 October 2011.
2011
Conference Publication
The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit
Rassam, L. J., Sinhal, N. P., Mackenzie, H., Bowman, R. V., Fong, K. M., Yang, I. A., Pratt, G., Fay, M., Hughes, B., Windsor, M. F. and Matar, K. (2011). The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia PA, United States: Lippincott Willams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc
Supervision
Availability
- Associate Professor Brett Hughes is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The changing face of head and neck cancer: addressing and advancing best-practice nutritional care to improve outcomes for patients with human papillomavirus-associated disease
Associate Advisor
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Doctor Philosophy
Developing predictive biomarkers for immunotherapy using deep spatial profiling
Associate Advisor
Other advisors: Associate Professor Arutha Kulasinghe
Completed supervision
-
2025
Doctor Philosophy
The investigation of the tumour microenvironment in head and neck squamous cell carcinoma to identify predictive biomarkers of response to immunotherapy
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor Arutha Kulasinghe
Media
Enquiries
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