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Associate Professor Brett Hughes
Associate Professor

Brett Hughes

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Overview

Background

Dr Brett Hughes graduated from the University of NSW with a Bachelor of Medical Science and Bachelor of Medicine and Surgery in 1997. He completed his postgraduate training in Canberra and Brisbane and was admitted as a Fellow of the Australian College of Physicians as a Specialist Medical Oncologist in 2005.

Dr Hughes is currently a Senior Staff Specialist Medical Oncologist at the RBWH and TPCH. He is also an Associate Professor at the University of Queensland since 2015. As the previous Clinical Director of Oncology (201-2017) and current Cancer Care Services Research lead at TPCH, Dr Hughes has established both an independent TPCH Oncology unit and continuing TPCH’s reputation as a lung cancer research centre of excellence.

Dr Hughes is an active senior member of the Thoracic Oncology Group Australasia (TOGA) and the Trans Tasman Radiation Oncology Group (TROG). He is also heavily involved in many pivotal multicentre trials of cancer therapy at both TPCH and RBWH with his principal research interests in Lung cancer, Head & Neck cancer, Mesothelioma, cutaneous SCC and Thyroid cancer. He has published over 100 peer review papers. Dr Hughes is also involved in undergraduate and post graduate teaching in his fields of research interest.

Availability

Associate Professor Brett Hughes is:
Available for supervision

Works

Search Professor Brett Hughes’s works on UQ eSpace

194 works between 2004 and 2025

181 - 194 of 194 works

2012

Journal Article

Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib

Punnoose, Elizabeth A., Atwal, Siminder, Liu, Weiqun, Raja, Rajiv, Fine, Bernard M., Hughes, Brett G. M., Hicks, Rodney J., Hampton, Garret M., Amler, Lukas C., Pirzkall, Andrea and Lackner, Mark R. (2012). Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib. Clinical Cancer Research, 18 (8), 2391-2401. doi: 10.1158/1078-0432.CCR-11-3148

Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib

2012

Conference Publication

Safety of bevacizumab used in routine practice in patients with metastatic colorectal cancer

Dzienis, M., Malczewski, A., Goh, J., Hughes, B., Eastgate, M., Wyld, D. and Burge, M. (2012). Safety of bevacizumab used in routine practice in patients with metastatic colorectal cancer. Medical Oncology Group of Australia Incorporated Annual Scientific Meeting, Program and Abstracts: Targeting Cancer from Diagnosis to Cure & 5th Annual COGNO Annual Scientific Meeting, Brisbane, QLD Australia, 8-10 August 2012. Wiley-Blackwell Publishing.

Safety of bevacizumab used in routine practice in patients with metastatic colorectal cancer

2012

Journal Article

Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review

So, W. K. W., Chan, R. J., Chan, D. N. S., Hughes, B. G. M., Chair, S. Y., Choi, K. C. and Chan, C. W. H. (2012). Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review. European Journal of Cancer, 48 (15), 2391-2408. doi: 10.1016/j.ejca.2012.04.005

Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review

2011

Journal Article

Medical management of mesothelioma

Bowman, Rayleen, Relan, Vandana and Hughes, Brett (2011). Medical management of mesothelioma. Australian Prescriber, 34 (5), 144-147. doi: 10.18773/austprescr.2011.076

Medical management of mesothelioma

2011

Journal Article

Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib

Mileshkin, Linda, Hicks, Rodney J., Hughes, Brett G. M., Mitchell, Paul L. R., Charu, Veena, Gitlitz, Barbara J., Macfarlane, David, Solomon, Benjamin, Amler, Lukas C., Yu, Wei, Pirzkall, Andrea and Fine, Bernard M. (2011). Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib. Clinical Cancer Research, 17 (10), 3304-3315. doi: 10.1158/1078-0432.CCR-10-2763

Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib

2011

Journal Article

Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer

Tran, Khoi, Bigby, Kieron J., Hughes, Brett G., Lee, Lawrence and Allison, Roger (2011). Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer. Asia-Pacific Journal of Clinical Oncology, 7 (1), 11-14. doi: 10.1111/j.1743-7563.2010.01332.x

Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer

2011

Conference Publication

The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit

Rassam, L. J., Sinhal, N. P., Mackenzie, H., Bowman, R. V., Fong, K. M., Yang, I. A., Pratt, G., Fay, M., Hughes, B., Windsor, M. F. and Matar, K. (2011). The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-8 October 2011. Philadelphia PA, United States: Lippincott Willams & Wilkins. doi: 10.1097/01.JTO.0000394634.73009.dc

The lung cancer journey - a review from the prince charles hospital pulmonary malignancy unit

2011

Conference Publication

Challenging the distal-to-proximal technique in the administration of anti-cancer therapies: A prospective cohort study

Alexander, Alison, Chan, Raymond, Bransdon, Maree, Hughes, Brett, Brown, Leisa and Graham, Therese (2011). Challenging the distal-to-proximal technique in the administration of anti-cancer therapies: A prospective cohort study. The 20th annual RBWH Health Care Symposium: Personalised Health Care, Herston, Brisbane, QLD, Australia, 10-14 October 2011.

Challenging the distal-to-proximal technique in the administration of anti-cancer therapies: A prospective cohort study

2010

Journal Article

Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme

Francesconi, Alessandra B., Dupre, Simon, Matos, Marco, Martin, David, Hughes, Brett G., Wyld, David K. and Lickliter, Jason D. (2010). Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme. Journal of Clinical Neuroscience, 17 (8), 970-974. doi: 10.1016/j.jocn.2009.12.009

Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme

2009

Journal Article

The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT

Lee, Joseph C., Hartnett, Gemma F., Hughes, Brett G.M. and Ravi Kumar, Aravind S. (2009). The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT. Nuclear Medicine Communications, 30 (5), 333-337. doi: 10.1097/MNM.0b013e32832999fa

The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT

2005

Journal Article

Life-threatening interaction between complementary medicines: Cyanide toxicity following ingestion of amygdalin and vitamin C

Bromley, Jonathan, Hughes, Brett G.M., Leong, David C.S. and Buckley, Nicholas A. (2005). Life-threatening interaction between complementary medicines: Cyanide toxicity following ingestion of amygdalin and vitamin C. Annals of Pharmacotherapy, 39 (9), 1566-1569. doi: 10.1345/aph.1E634

Life-threatening interaction between complementary medicines: Cyanide toxicity following ingestion of amygdalin and vitamin C

2005

Journal Article

Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): Randomized controlled trial

Greenhalgh, R. M., Brown, L. C., Epstein, D., Kwong, G. P.S., Powell, J. T., Sculpher, M. J., Thompson, S. G., Greenhalgh, R. M., Allison, D. J., Bell, P. R.F., Buxton, M. J., Harris, P. L., Hopkinson, B. R., Powell, J. T., Russell, I. T., Thompson, S. G., Brown, L. C., Barton, G., Epstein, D., Kwong, G. P.S., Macran, S., Manca, A., Reise, J. A., Williams, A., Greenhalgh, R. M., Beard, J. D., Buxton, M. J., Harris, P. L., Powell, J. T. ... Wilson, L. (2005). Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): Randomized controlled trial. The Lancet, 365 (9478), 2179-2186. doi: 10.1016/S0140-6736(05)66627-5

Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): Randomized controlled trial

2005

Journal Article

Docetaxel-induced myositis: Report of a novel side-effect [1]

Hughes, B. G.M. and Stuart-Harris, R. (2005). Docetaxel-induced myositis: Report of a novel side-effect [1]. Internal Medicine Journal, 35 (6), 369-370. doi: 10.1111/j.1445-5994.2005.00846.x

Docetaxel-induced myositis: Report of a novel side-effect [1]

2004

Journal Article

Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: Case report

Hughes, Brett, Yip, Desmond, Goldstein, David, Waring, Paul, Beshay, Victoria and Chong, Guan (2004). Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: Case report. BMC Cancer, 4 (1) 74. doi: 10.1186/1471-2407-4-74

Cerebral relapse of metastatic gastrointestinal stromal tumor during treatment with imatinib mesylate: Case report

Funding

Current funding

  • 2024 - 2026
    From Pixels to Prognosis: Harnessing single-cell spatial analysis to predict and improve immunotherapy response in lung cancer
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2026
    Developing a multi-omic, high-dimensional assessment of head and neck cancer
    Garnett Passe and Rodney Williams Memorial Foundation Conjoint Grant
    Open grant

Past funding

  • 2014 - 2016
    NITRO Trial: A randomised phase III trial of adding nitroglycerin to first line chemotherapy for advanced non-small cell lung cancer (NHMRC Project Grant administered by the University of Sydney)
    University of Sydney
    Open grant
  • 2013 - 2016
    Improving quality of life in high-risk cancer populations: a randomised trial of a structured intervention for head and neck cancer survivors
    NHMRC Project Grant
    Open grant

Supervision

Availability

Associate Professor Brett Hughes is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    The changing face of head and neck cancer: addressing and advancing best-practice nutritional care to improve outcomes for patients with human papillomavirus-associated disease

    Associate Advisor

  • Doctor Philosophy

    Developing predictive biomarkers for immunotherapy using deep spatial profiling

    Associate Advisor

    Other advisors: Associate Professor Arutha Kulasinghe

Completed supervision

Media

Enquiries

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