Overview
Background
Since joining the Centre for Nutrition and Food Science in 2004, my work has focussed on food structure and how it changes during digestion and fermentation. I use NMR spectroscopy and wet chemistry techniques, to characterise polysaccharides particularly: starch, plant cell walls, dietary fibre and cellulose. My research has resulted in the publication of 93 papers with over 6000 citations and a H-index of 39 (scopus). I regularly review papers for Food Hydrocolloids and Carbohydrate polymers. I have co-supervised eight PhDs to completion and am currently co-supervising four PhD students and am principal supervisor to one PhD and two masters students.
After graduating with a Bachelor of Science (Honours, 1997, UQ) and PhD in Inorganic Chemistry (2002, UQ) I worked with Prof David Fairlie (h-index 104, 42, 140 citations) to study peptide synthesis and high-field, multi-dimensional NMR.
I have practical experience with in vitro and digestion and fermentation and havecollaborated to perfect a batch fermentation system to compare the fermentability of a number of complex dietary fibres using human faecal inoculum. Using this methodology, I have studied how the chemistry and architecture of dietary fibres affects the digestion and fermentation of starches and dietary fibres. My Skills in NMR spectroscopy have enabled me to develop methods for quantifying starch molecular order and to quantify Short Chain Fatty acids and other fermemetabolites.
Availability
- Dr Bernadine Flanagan is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Investigating food structure and how it affects digestibility and fermentability.
Characterising starch and dietary fibres and exploring how they change in response to differences in processing conditions. How does food architecture affect the digestibility and fermentability of food and feeds. Using spectroscopy and analytical chemistry techniques to explore the composition and structures of food and feeds. Determining how the interaction of plant cell wall polysaccharides influences their structure and function with particular focus on the interactions of cellulose hemicelluloses. How the density and solubility of plant cell wall components drives fermentability.
Research impacts
Over the last twenty years (13 years FTE) I have been part of many multi-disciplinary teams working with industry, government and fellow university based researchers nationally and internationally. For Six years as part of the CSIRO Food Futures Flagship and then for 7 years as a member of the ARC Centre of Excellence for Plant Cell walls, a team of over 80 researchers, based at UA, UM, ANSTO and international collaborators in the UK and Sweden. These collaborations lead to many multi-disciplinary publications with a focus of polysaccharide structure and function. Using NMR, I established new methods for polysaccharide structure analysis and increased our understanding of complex plant cell wall structure relationships.
In 2005 I was awarded a UQ New Staff Research Start Up Fund. In 2023 I was a CI on a successful $1.68 million ARC LIEF bid for a national network for magnetic resonance spectroscopy. I am a CI on a recently awarded a $788, 130 ARC Linkage grant, LP240100343, in this project I will lead the activities in polysaccharide structure and characterisation. As a result of my interest in plant polysaccharides, I was voted Vice Chair of Australasian Grain Science Association (AGSA) and was appointed 2025 AGSA Brisbane conference chair.
Works
Search Professor Bernadine Flanagan’s works on UQ eSpace
2009
Journal Article
Influence of different carbon sources on bacterial cellulose production by Gluconacetobacter xylinus strain ATCC 53524
Mikkelsen, D., Flanagan, B. M., Dykes, G. A. and Gidley, M. J. (2009). Influence of different carbon sources on bacterial cellulose production by Gluconacetobacter xylinus strain ATCC 53524. Journal of Applied Microbiology, 107 (2), 576-583. doi: 10.1111/j.1365-2672.2009.04226.x
2009
Journal Article
Effects of processing high amylose maize starches under controlled conditions on structural organisation and amylase digestibility
Htoon, A., Shrestha, A. K., Flanagan, B. M., Lopez-Rubio, A., Bird, A. R., Gilbert, E. P. and Gidley, M. J. (2009). Effects of processing high amylose maize starches under controlled conditions on structural organisation and amylase digestibility. Carbohydrate Polymers, 75 (2), 236-245. doi: 10.1016/j.carbpol.2008.06.016
2009
Conference Publication
NMR study of molecular interactions between bile salts and cereal non-starch polysaccharides
Gunness, P., Flanagan, B.M. and Gidley, M.J. (2009). NMR study of molecular interactions between bile salts and cereal non-starch polysaccharides. Australian Cereal Chemistry Conference, Wagga Wagga, Australia, 2009.
2008
Journal Article
Characterization of cellulose production by a Gluconacetobacter xylinus strain from Kombucha
Nguyen, Vu Tuan, Flanagan, Bernadine M., Gidley, Michael J. and Dykes, Gary A. (2008). Characterization of cellulose production by a Gluconacetobacter xylinus strain from Kombucha. Current Microbiology, 57 (5), 449-453. doi: 10.1007/s00284-008-9228-3
2008
Journal Article
A novel approach for calculating starch crystallinity and its correlation with double helix content: a combined XRD and NMR study
Lopez-Rubio, Amparo, Flanagan, Bernadine M., Gilbert, Elliot P. and Gidley, Michael J. (2008). A novel approach for calculating starch crystallinity and its correlation with double helix content: a combined XRD and NMR study. Biopolymers, 89 (9), 761-768. doi: 10.1002/bip.21005
2008
Journal Article
Molecular rearrangement of starch during in vitro digestion: Toward a better understanding of enzyme resistant starch formation in processed starches
Lopez-Rubio, Amparo, Flanagan, Bernadine M., Shrestha, Ashok K., Gidley, Michael J. and Gilbert, Elliot P. (2008). Molecular rearrangement of starch during in vitro digestion: Toward a better understanding of enzyme resistant starch formation in processed starches. Biomacromolecules, 9 (7), 1951-1958. doi: 10.1021/bm800213h
2008
Conference Publication
Nutritional bioactives in tropical fruit
Wilkinson, A. S., Lin, C. N., Flanagan, B., Dietzgen, R., Shaw, P. N., Monteith, G. R., Roberts-Thomson, S. J. and Gidley, M. J. (2008). Nutritional bioactives in tropical fruit. Experimental Biology 2008: Today's Research: Tomorrow's Health, San Diego, U.S., 5-6 April, 2008.
2008
Conference Publication
Mechanisms behind the cholesterol-lowering effect of soluble dietary fibres
Gunness, P., Flanagan, B. M. and Gidley, M. J. (2008). Mechanisms behind the cholesterol-lowering effect of soluble dietary fibres. Nutrition Society of Australia 32nd Annual Scientific Meeting: Conference 2008, Stamford Grand Hotel, Adelaide, Australia, 30 November-3 December 2008. Adelaide, Australia: The Nutrition Society of Australia.
2008
Conference Publication
Bacterial cellulose composites: Models for primary plant cell walls of cereals and grasses
Mikkelsen, D., Flanagan, B., Dykes, G. and Gidley, M. (2008). Bacterial cellulose composites: Models for primary plant cell walls of cereals and grasses. ASM 2008: Annual Scientific Meeting & Exhibition of the Australian Society for Microbiology, Melbourne, VIC, Australia, 6-10 July 2008. Melbourne, VIC, Australia: Australian Society for Microbiology.
2007
Journal Article
Hepta and octapeptide agonists of protease-activated receptor 2
Devlin, M. G., Pfeiffer, B., Flanagan, B. M., Beyer, R., Cocks, T. M and Fairlie, D. P. (2007). Hepta and octapeptide agonists of protease-activated receptor 2. Journal of Peptide Science, 13 (12), 856-861. doi: 10.1002/psc.912
2007
Journal Article
A refined agonist pharmacophore for protease activated receptor 2
Barry, Grant D., Suen, Jacky Y., Low, Heng Boon, Pfeiffer, Bernhard, Flanagan, Bernadine, Halili, Maria, Le, Giang T. and Fairlie, David P. (2007). A refined agonist pharmacophore for protease activated receptor 2. Bioorganic & Medicinal Chemistry Letters, 17 (20), 5552-5557. doi: 10.1016/j.bmcl.2007.08.026
2007
Journal Article
A method for estimating the nature and relative proportions of amorphous, single, and double-helical components in starch granules by 13C CP/MAS NMR
Tan, Ihwa, Flanagan, Bernadine M., Halley, Peter J., Whittaker, Andrew K. and Gidley, Michael J. (2007). A method for estimating the nature and relative proportions of amorphous, single, and double-helical components in starch granules by 13C CP/MAS NMR. Biomacromolecules, 8 (3), 885-891. doi: 10.1021/bm060988a
2007
Conference Publication
Effect of processing high-amylose maize starches under controlled conditions on structural organization and amylase digestibility
Shrestha, A. K., Htoon, A., Flanagan, B. M., Lopez-Rubio, S., Uthayakumaran, S., Chanvrier, H., Bird, A. R., Gilbert, E. P. and Gidley, M. D. (2007). Effect of processing high-amylose maize starches under controlled conditions on structural organization and amylase digestibility. 14th European Carbohydrate Symposium, Lubeck, Germany, 2-7 September, 2007.
2007
Conference Publication
New insights into starch molecular conformation from solid state 13C NMR spectroscopy
Flanagan, B. M., Tan, I., Halley, P. J., Whittaker, A. K. and Gidley, M. (2007). New insights into starch molecular conformation from solid state 13C NMR spectroscopy. 56th Australian Cereal Chemistry Conference, Freemantle, 10-14 September 2006. North Melbourne: Royal Australian Chemical Institute.
2007
Conference Publication
Effects Of Mango Extracts and Components On Breast Cancer Cell Proliferation
Wilkinson, A. S., Lin, C. N., Flanagan, B. M., Dietzgen, R. G., Monteith, G. R., Shaw, P. N., Roberts-Thomson, S. J. and Gidley, M. J. (2007). Effects Of Mango Extracts and Components On Breast Cancer Cell Proliferation. 41st Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and 10th Southeast Asian Western Pacific Regional Meeting of Pharmacologists, Adelaide, South Australia, 2-6 December 2007. Victoria, Australia: ASCEPT.
2007
Conference Publication
Applications of fourier transform infrared microspectroscopy in cereals
Flanagan, B. M. and Gidley, M. (2007). Applications of fourier transform infrared microspectroscopy in cereals. 57th Australian Cereal Chemistry Conference, Melbourne, Victoria, 5-10 August 2007. North Melbourne: Cereal Chemistry Division.
2006
Journal Article
Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops
Singh, Y, Hoang, HN, Flanagan, B and Fairlie, DP (2006). Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops. Organic Letters, 8 (6), 1053-1056. doi: 10.1021/ol052842e
2006
Conference Publication
Digestibility of starches: effects of polymer conformation and food structure
Gidley, M, Flanagan, B M, Shrestha, A K, Rubio, A.L., Gilbert,, Htoon,, Chanvrier,, Uthayakumaran,, Lillford, P.J., Xhou, X.K., Bird, A.R. and Topping, D.L. (2006). Digestibility of starches: effects of polymer conformation and food structure. Thirtieth Annual Scientific Meeting of the Nutr Soc of Aust, Sydney, 29 November - 2 December 2006. Melbourne: HEC Press.
2006
Conference Publication
Nutritional bioactives in tropical fruit
Wilkinson, A, Hewavitharana, A, Flanagan, B M, Dietzgen, R G, Monteith, G R, Shaw, P N, Roberts-Thomson, S J and Gidley, M (2006). Nutritional bioactives in tropical fruit. The 3rd Australian Health & Medical Research Congress, Melbourne Convention Centre, Melbourne, Australia, 26 November-1 December, 2006. Melbourne, Vic, Australia: National Health and Medical Research Council.
2005
Conference Publication
Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models
Sutherland, A., Hewavitharana, A., Flanagan, B. M., Monteith, G. R., Shaw, N., Roberts-Thomson, S. J. and Gidley, M. (2005). Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models. 29th Annual Scientific Meeting of Nutrition Society of Australia, Melbourne, Vic, Australia, 30 November-3 December, 2005. Clayton, Vic., Australia: Blackwell Science Asia.
Supervision
Availability
- Dr Bernadine Flanagan is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Improving protein digestion in broiler chicken by application of exogenous enzymes
Principal Advisor
Other advisors: Professor Mike Gidley, Professor Eugeni Roura
-
Doctor Philosophy
Controlling feed digestion in pigs to remove the need for antimicrobials
Associate Advisor
Other advisors: Professor Eugeni Roura, Professor Mike Gidley
-
Doctor Philosophy
Sustainable Precision Feeding in Broiler Chickens in Australia
Associate Advisor
Other advisors: Professor Mike Gidley, Professor Eugeni Roura
-
Doctor Philosophy
Utilization of non-protein fractions of legumes in the food industry
Associate Advisor
Other advisors: Professor Mike Gidley
-
Doctor Philosophy
Understanding the relationship between the shape, size and local density of food gels and their functionality in vitro
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Heather Shewan, Professor Mike Gidley
Completed supervision
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2025
Doctor Philosophy
Xylo-oligosaccharides, gastrointestinal function and microbiota in broiler chickens
Associate Advisor
Other advisors: Dr Conny Turni, Dr Lida Omaleki, Professor Eugeni Roura
-
2024
Doctor Philosophy
Wattleseeds for nutritional foods
Associate Advisor
Other advisors: Professor Heather Smyth, Professor Mike Gidley
-
2024
Doctor Philosophy
Microbiota interactions and functionality in response to nut consumption and in vitro fermentation
Associate Advisor
Other advisors: Professor Mike Gidley, Dr Deirdre Mikkelsen
-
2023
Doctor Philosophy
Dietary fibre concentration and particle size drive in vitro gut microbial fermentation behaviours
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Mike Gidley
-
2022
Doctor Philosophy
Preparation and characterization of chemically modified wheat starch as a depressant of pyrite and graphite
Associate Advisor
Other advisors: Professor Mike Gidley
-
2021
Doctor Philosophy
In Vitro Fermentation of Insoluble Dietary Fibers and Undigested Fractions from Plant Food Sources
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Mike Gidley
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2021
Doctor Philosophy
In vitro gut microbial fermentation of models for plant dietary fibre
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Mike Gidley
-
2019
Doctor Philosophy
BACTERIAL MEDIATED ENZYMATIC METABOLISM OF ARABINOXYLAN AND GALACTOXYLOGLUCAN UNDER IN VITRO FERMENTATION CONDITIONS
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Mike Gidley
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2012
Doctor Philosophy
Mechanisms behind the cholesterol-reducing effect of cereal soluble dietary fibres: (1,3:1,4) beta glucan & arabinoxylan
Associate Advisor
Other advisors: Professor Mike Gidley
Media
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