
Overview
Background
Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Chronic sinusitis
Alternative treatment with probiotics
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Otitis Media
Alternative treatment with probiotics
Research impacts
Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics
Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.
Works
Search Professor Anders Cervin’s works on UQ eSpace
2024
Journal Article
Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus
Yarlagadda, Tejasri, Zhu, Yanshan, Snape, Natale, Carey, Alison, Bryan, Emily, Maresco-Pennisi, Diane, Coleman, Andrea, Cervin, Anders and Spann, Kirsten (2024). Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus. Journal of Applied Microbiology, 135 (2) lxae018. doi: 10.1093/jambio/lxae018
2024
Journal Article
Multi-disciplinary expert perspective on the management of type 2 inflammation-driven severe CRSwNP: a brief overview of pathophysiology and recent clinical insights
Toppila-Salmi, Sanna, Bjermer, Leif, Cardell, Lars-Olaf, Cervin, Anders, Heinikari, Tuuli, Lehtimäki, Lauri, Lundberg, Marie, Richter, Jens C. and Sillanpää, Saara (2024). Multi-disciplinary expert perspective on the management of type 2 inflammation-driven severe CRSwNP: a brief overview of pathophysiology and recent clinical insights. Journal of Asthma and Allergy, 17, 431-439. doi: 10.2147/JAA.S447093
2023
Journal Article
Impact of long-acting implantable LYR-210 corticosteroid matrices on quality of life of patients with chronic rhinosinusitis in the LANTERN study
Rimmer, Joanne, Cervin, Anders, Wrobel, Agnieszka, Gartung, Allison, Brayton, Lindsay, Shao, James and Belanger, Vineeta (2023). Impact of long-acting implantable LYR-210 corticosteroid matrices on quality of life of patients with chronic rhinosinusitis in the LANTERN study. International Forum of Allergy and Rhinology, 13 (9), 1821-1824. doi: 10.1002/alr.23139
2023
Journal Article
Upper airway microbiome transplantation for patients with chronic rhinosinusitis
Mårtensson, Anders, Cervin-Hoberg, Charlotte, Huygens, Flavia, Lindstedt, Malin, Sakellariou, Christina, Greiff, Lennart and Cervin, Anders (2023). Upper airway microbiome transplantation for patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 13 (6), 979-988. doi: 10.1002/alr.23122
2023
Journal Article
The EUFOREA pocket guide for chronic rhinosinusitis
Hellings, P. W., Fokkens, W. J., Orlandi, R., Adriaensen, G. F., Alobid, I., Baroody, F. M., Bjermer, L., Senior, B. A., Cervin, A., Cohen, N. A., Constantinidis, J., De Corso, E., Desrosiers, M., Diamant, Z., Douglas, R. G., Gane, S., Gevaert, P., Han, J. K., Harvey, R. J., Hopkins, C., Kern, R. C., Landis, B. N., Lee, J. T., Lee, S. E., Leunig, A., Lund, V. J., Bernal-Sprekelsen, M., Mullol, J., Philpott, C. ... Wagenmann, M. (2023). The EUFOREA pocket guide for chronic rhinosinusitis. Rhinology, 61 (1), 85-89. doi: 10.4193/Rhin22.344
2023
Journal Article
Consensus criteria for chronic rhinosinusitis disease control: an international Delphi Study*
Sedaghat, Ahmad R., Fokkens, Wytske J., Lund, Valerie J., Hellings, Peter W., Kern, Robert C., Reitsma, Sietze, Toppila-Salmi, Sanna, Bernal-Sprekelsen, Manuel, Mullol, Joaquim, Gevaert, Philippe, Teeling, Thijs, Alobid, Isam, Anselmo-Lima, Wilma T., Baroody, Fuad M., Cervin, Anders, Cohen, Noam A., Constantinidis, Jannis, Gabory, Ludovic De, Desrosiers, Martin, Harvey, Richard J., Kalogjera, Livije, Knill, Andrew, Landis, Basile N., Meco, Cem, Philpott, Carl M., Ryan, Dermot, Schlosser, Rodney J., Senior, Brent A., Smith, Timothy L. ... Hopkins, Claire (2023). Consensus criteria for chronic rhinosinusitis disease control: an international Delphi Study*. Rhinology, 61 (6), 519-530. doi: 10.4193/Rhin23.335
2022
Journal Article
Nasal administration of a probiotic assemblage in allergic rhinitis: a randomised placebo-controlled crossover trial
Mårtensson, Anders, Nordström, Franziska U., Cervin-Hoberg, Charlotte, Lindstedt, Malin, Sakellariou, Christina, Cervin, Anders and Greiff, Lennart (2022). Nasal administration of a probiotic assemblage in allergic rhinitis: a randomised placebo-controlled crossover trial. Clinical and Experimental Allergy, 52 (6), 774-783. doi: 10.1111/cea.14098
2022
Journal Article
In vitro Inhibition of respiratory pathogens by lactobacillus and alpha haemolytic streptococci from Aboriginal and Torres Strait Islander children
Coleman, Andrea, Håkansson, Alexander, Grahn Håkansson, Eva, Cottrell, Kyra, Bialasiewicz, Seweryn, Zaugg, Julian and Cervin, Anders (2022). In vitro Inhibition of respiratory pathogens by lactobacillus and alpha haemolytic streptococci from Aboriginal and Torres Strait Islander children. Journal of Applied Microbiology, 132 (3), 2368-2378. doi: 10.1111/jam.15320
2022
Journal Article
Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study
Cervin, Anders, Rimmer, Joanne, Wrobel, Agnieszka, Abelak, Yogen, Brayton, Lindsay and Kuang, Yina (2022). Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study. International Forum of Allergy and Rhinology, 12 (2), 147-159. doi: 10.1002/alr.22883
2021
Journal Article
Upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease
Coleman, Andrea, Zaugg, Julian, Wood, Amanda, Cottrell, Kyra, Håkansson, Eva Grahn, Adams, Jasmyn, Brown, Matthew, Cervin, Anders and Bialasiewicz, Seweryn (2021). Upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease. Microbiology Spectrum, 9 (2) e00367-21, e0036721. doi: 10.1128/spectrum.00367-21
2021
Journal Article
A survey of Queensland medical education in otolaryngology
Yau, Stephanie, Wong, Michael and Cervin, Anders (2021). A survey of Queensland medical education in otolaryngology. Australian Journal of Otolaryngology, 4 (June) ajo2087, 4. doi: 10.21037/ajo-20-87
2021
Journal Article
COVID-19 swab-related skull base injury
Mistry, Sandeep G., Walker, Wallace, Earnshaw, James and Cervin, Anders (2021). COVID-19 swab-related skull base injury. Medical Journal of Australia, 214 (10), 457-459.e1. doi: 10.5694/mja2.51082
2021
Journal Article
Radiofrequency ablation in the treatment of inferior turbinate hypertrophy
Chaudhry, Sarah, Maresco-Pennisi, Diane and Cervin, Anders (2021). Radiofrequency ablation in the treatment of inferior turbinate hypertrophy. Australian Journal of Otolaryngology, 4 (March) 5, 4. doi: 10.21037/ajo-20-52
2021
Journal Article
Upper respiratory microbiota in relation to ear and nose health among Australian Aboriginal and Torres Strait Islander children
Coleman, Andrea, Bialasiewicz, Seweryn, Marsh, Robyn L., Grahn Håkansson, Eva, Cottrell, Kyra, Wood, Amanda, Jayasundara, Nadeesha, Ware, Robert S., Zaugg, Julian, Sidjabat, Hanna E., Adams, Jasmyn, Ferguson, Josephine, Brown, Matthew, Roos, Kristian and Cervin, Anders (2021). Upper respiratory microbiota in relation to ear and nose health among Australian Aboriginal and Torres Strait Islander children. Journal of the Pediatric Infectious Diseases Society, 10 (4), 468-476. doi: 10.1093/jpids/piaa141
2020
Journal Article
Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures
Marsh, Robyn L., Aho, Celestine, Beissbarth, Jemima, Bialasiewicz, Seweryn, Binks, Michael, Cervin, Anders, Kirkham, Lea-Ann S., Lemon, Katherine P., Slack, Mary P.E. and Smith-Vaughan, Heidi C. (2020). Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures. International Journal of Pediatric Otorhinolaryngology, 130 (Supp. 1) 109836, 109836. doi: 10.1016/j.ijporl.2019.109836
2020
Journal Article
European Position Paper on Rhinosinusitis and Nasal Polyps 2020
Fokkens, W. J., Lund, V. J., Hopkins, C., Hellings, P. W., Kern, R., Reitsma, S., Toppila-Salmi, S., Bernal-Sprekelsen, M., Mullol, J., Alobid, I., Terezinha Anselmo-Lima, W., Bachert, C., Baroody, F., von Buchwald, C., Cervin, A., Cohen, N., Constantinidis, J., De Gabory, L., Desrosiers, M., Diamant, Z., Douglas, R. G., Gevaert, P. H., Hafner, A., Harvey, R. J., Joos, G. F., Kalogjera, L., Knill, A., Kocks, J. H., Landis, B. N. ... Stjarne, P. (2020). European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology, 58 (S29), 1-464. doi: 10.4193/Rhin20.600
2019
Journal Article
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
Bachert, Claus, Han, Joseph K, Desrosiers, Martin, Hellings, Peter W, Amin, Nikhil, Lee, Stella E, Mullol, Joaquim, Greos, Leon S, Bosso, John V, Laidlaw, Tanya M, Cervin, Anders U, Maspero, Jorge F, Hopkins, Claire, Olze, Heidi, Canonica, G Walter, Paggiaro, Pierluigi, Cho, Seong H, Fokkens, Wytske J, Fujieda, Shigeharu, Zhang, Mei, Lu, Xin, Fan, Chunpeng, Draikiwicz, Steven, Kamat, Siddhesh A, Khan, Asif, Pirozzi, Gianluca, Patel, Naimish, Graham, Neil M H, Ruddy, Marcella ... Mannent, Leda P (2019). Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. The Lancet, 394 (10209), 1638-1650. doi: 10.1016/S0140-6736(19)31881-1
2019
Journal Article
Oral corticosteroids for painful acute otitis externa (swimmer's ear): a triple-blind randomised controlled trial
Balch, Graeme, Heal, Clare, Cervin, Anders and Gunnarsson, Ronny (2019). Oral corticosteroids for painful acute otitis externa (swimmer's ear): a triple-blind randomised controlled trial. Australian Journal of General Practice, 48 (8), 565-572. doi: 10.31128/AJGP-12-18-4795
2019
Journal Article
Inflammation and endotyping in chronic rhinosinusitis — a paradigm shift
Ahern, Sinead and Cervin, Anders (2019). Inflammation and endotyping in chronic rhinosinusitis — a paradigm shift. Medicina, 55 (4) 95, 95. doi: 10.3390/medicina55040095
2019
Journal Article
Phase 1 clinical study to assess the safety of a novel drug delivery system providing long-term topical steroid therapy for chronic rhinosinusitis
Douglas, Richard G., Psaltis, Alkis J., Rimmer, Joanne, Kuruvilla, Tom, Cervin, Anders and Kuang, Yina (2019). Phase 1 clinical study to assess the safety of a novel drug delivery system providing long-term topical steroid therapy for chronic rhinosinusitis. International Forum of Allergy and Rhinology, 9 (4), 378-387. doi: 10.1002/alr.22288
Funding
Current funding
Supervision
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
Principal Advisor
Other advisors: Dr Diane Maresco-Pennisi
Completed supervision
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2021
Doctor Philosophy
The microbiome of otitis media and development of a probiotic to prevent otitis media in Indigenous Australian children
Principal Advisor
Other advisors: Dr Seweryn Bialasiewicz
Media
Enquiries
Contact Honorary Professor Anders Cervin directly for media enquiries about:
- sinusitis
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