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Honorary Professor Anders Cervin
Honorary Professor

Anders Cervin

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Overview

Background

Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.

Availability

Honorary Professor Anders Cervin is:
Available for supervision
Media expert

Research interests

  • Chronic sinusitis

    Alternative treatment with probiotics

  • Otitis Media

    Alternative treatment with probiotics

Research impacts

Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics

Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.

Works

Search Professor Anders Cervin’s works on UQ eSpace

85 works between 1988 and 2024

1 - 20 of 85 works

2024

Journal Article

Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus

Yarlagadda, Tejasri, Zhu, Yanshan, Snape, Natale, Carey, Alison, Bryan, Emily, Maresco-Pennisi, Diane, Coleman, Andrea, Cervin, Anders and Spann, Kirsten (2024). Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus. Journal of Applied Microbiology, 135 (2) lxae018. doi: 10.1093/jambio/lxae018

Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus

2024

Journal Article

Multi-disciplinary expert perspective on the management of type 2 inflammation-driven severe CRSwNP: a brief overview of pathophysiology and recent clinical insights

Toppila-Salmi, Sanna, Bjermer, Leif, Cardell, Lars-Olaf, Cervin, Anders, Heinikari, Tuuli, Lehtimäki, Lauri, Lundberg, Marie, Richter, Jens C. and Sillanpää, Saara (2024). Multi-disciplinary expert perspective on the management of type 2 inflammation-driven severe CRSwNP: a brief overview of pathophysiology and recent clinical insights. Journal of Asthma and Allergy, 17, 431-439. doi: 10.2147/JAA.S447093

Multi-disciplinary expert perspective on the management of type 2 inflammation-driven severe CRSwNP: a brief overview of pathophysiology and recent clinical insights

2023

Journal Article

Impact of long-acting implantable LYR-210 corticosteroid matrices on quality of life of patients with chronic rhinosinusitis in the LANTERN study

Rimmer, Joanne, Cervin, Anders, Wrobel, Agnieszka, Gartung, Allison, Brayton, Lindsay, Shao, James and Belanger, Vineeta (2023). Impact of long-acting implantable LYR-210 corticosteroid matrices on quality of life of patients with chronic rhinosinusitis in the LANTERN study. International Forum of Allergy and Rhinology, 13 (9), 1821-1824. doi: 10.1002/alr.23139

Impact of long-acting implantable LYR-210 corticosteroid matrices on quality of life of patients with chronic rhinosinusitis in the LANTERN study

2023

Journal Article

Upper airway microbiome transplantation for patients with chronic rhinosinusitis

Mårtensson, Anders, Cervin-Hoberg, Charlotte, Huygens, Flavia, Lindstedt, Malin, Sakellariou, Christina, Greiff, Lennart and Cervin, Anders (2023). Upper airway microbiome transplantation for patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 13 (6), 979-988. doi: 10.1002/alr.23122

Upper airway microbiome transplantation for patients with chronic rhinosinusitis

2023

Journal Article

The EUFOREA pocket guide for chronic rhinosinusitis

Hellings, P. W., Fokkens, W. J., Orlandi, R., Adriaensen, G. F., Alobid, I., Baroody, F. M., Bjermer, L., Senior, B. A., Cervin, A., Cohen, N. A., Constantinidis, J., De Corso, E., Desrosiers, M., Diamant, Z., Douglas, R. G., Gane, S., Gevaert, P., Han, J. K., Harvey, R. J., Hopkins, C., Kern, R. C., Landis, B. N., Lee, J. T., Lee, S. E., Leunig, A., Lund, V. J., Bernal-Sprekelsen, M., Mullol, J., Philpott, C. ... Wagenmann, M. (2023). The EUFOREA pocket guide for chronic rhinosinusitis. Rhinology, 61 (1), 85-89. doi: 10.4193/Rhin22.344

The EUFOREA pocket guide for chronic rhinosinusitis

2023

Journal Article

Consensus criteria for chronic rhinosinusitis disease control: an international Delphi Study*

Sedaghat, Ahmad R., Fokkens, Wytske J., Lund, Valerie J., Hellings, Peter W., Kern, Robert C., Reitsma, Sietze, Toppila-Salmi, Sanna, Bernal-Sprekelsen, Manuel, Mullol, Joaquim, Gevaert, Philippe, Teeling, Thijs, Alobid, Isam, Anselmo-Lima, Wilma T., Baroody, Fuad M., Cervin, Anders, Cohen, Noam A., Constantinidis, Jannis, Gabory, Ludovic De, Desrosiers, Martin, Harvey, Richard J., Kalogjera, Livije, Knill, Andrew, Landis, Basile N., Meco, Cem, Philpott, Carl M., Ryan, Dermot, Schlosser, Rodney J., Senior, Brent A., Smith, Timothy L. ... Hopkins, Claire (2023). Consensus criteria for chronic rhinosinusitis disease control: an international Delphi Study*. Rhinology, 61 (6), 519-530. doi: 10.4193/Rhin23.335

Consensus criteria for chronic rhinosinusitis disease control: an international Delphi Study*

2022

Journal Article

Nasal administration of a probiotic assemblage in allergic rhinitis: a randomised placebo-controlled crossover trial

Mårtensson, Anders, Nordström, Franziska U., Cervin-Hoberg, Charlotte, Lindstedt, Malin, Sakellariou, Christina, Cervin, Anders and Greiff, Lennart (2022). Nasal administration of a probiotic assemblage in allergic rhinitis: a randomised placebo-controlled crossover trial. Clinical and Experimental Allergy, 52 (6), 774-783. doi: 10.1111/cea.14098

Nasal administration of a probiotic assemblage in allergic rhinitis: a randomised placebo-controlled crossover trial

2022

Journal Article

In vitro Inhibition of respiratory pathogens by lactobacillus and alpha haemolytic streptococci from Aboriginal and Torres Strait Islander children

Coleman, Andrea, Håkansson, Alexander, Grahn Håkansson, Eva, Cottrell, Kyra, Bialasiewicz, Seweryn, Zaugg, Julian and Cervin, Anders (2022). In vitro Inhibition of respiratory pathogens by lactobacillus and alpha haemolytic streptococci from Aboriginal and Torres Strait Islander children. Journal of Applied Microbiology, 132 (3), 2368-2378. doi: 10.1111/jam.15320

In vitro Inhibition of respiratory pathogens by lactobacillus and alpha haemolytic streptococci from Aboriginal and Torres Strait Islander children

2022

Journal Article

Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study

Cervin, Anders, Rimmer, Joanne, Wrobel, Agnieszka, Abelak, Yogen, Brayton, Lindsay and Kuang, Yina (2022). Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study. International Forum of Allergy and Rhinology, 12 (2), 147-159. doi: 10.1002/alr.22883

Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study

2021

Journal Article

Upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease

Coleman, Andrea, Zaugg, Julian, Wood, Amanda, Cottrell, Kyra, Håkansson, Eva Grahn, Adams, Jasmyn, Brown, Matthew, Cervin, Anders and Bialasiewicz, Seweryn (2021). Upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease. Microbiology Spectrum, 9 (2) e00367-21, e0036721. doi: 10.1128/spectrum.00367-21

Upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease

2021

Journal Article

A survey of Queensland medical education in otolaryngology

Yau, Stephanie, Wong, Michael and Cervin, Anders (2021). A survey of Queensland medical education in otolaryngology. Australian Journal of Otolaryngology, 4 (June) ajo2087. doi: 10.21037/ajo-20-87

A survey of Queensland medical education in otolaryngology

2021

Journal Article

COVID-19 swab-related skull base injury

Mistry, Sandeep G., Walker, Wallace, Earnshaw, James and Cervin, Anders (2021). COVID-19 swab-related skull base injury. Medical Journal of Australia, 214 (10), 457-459.e1. doi: 10.5694/mja2.51082

COVID-19 swab-related skull base injury

2021

Journal Article

Radiofrequency ablation in the treatment of inferior turbinate hypertrophy

Chaudhry, Sarah, Maresco-Pennisi, Diane and Cervin, Anders (2021). Radiofrequency ablation in the treatment of inferior turbinate hypertrophy. Australian Journal of Otolaryngology, 4 (March) 5. doi: 10.21037/ajo-20-52

Radiofrequency ablation in the treatment of inferior turbinate hypertrophy

2021

Journal Article

Upper respiratory microbiota in relation to ear and nose health among Australian Aboriginal and Torres Strait Islander children

Coleman, Andrea, Bialasiewicz, Seweryn, Marsh, Robyn L., Grahn Håkansson, Eva, Cottrell, Kyra, Wood, Amanda, Jayasundara, Nadeesha, Ware, Robert S., Zaugg, Julian, Sidjabat, Hanna E., Adams, Jasmyn, Ferguson, Josephine, Brown, Matthew, Roos, Kristian and Cervin, Anders (2021). Upper respiratory microbiota in relation to ear and nose health among Australian Aboriginal and Torres Strait Islander children. Journal of the Pediatric Infectious Diseases Society, 10 (4), 468-476. doi: 10.1093/jpids/piaa141

Upper respiratory microbiota in relation to ear and nose health among Australian Aboriginal and Torres Strait Islander children

2020

Journal Article

Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

Marsh, Robyn L., Aho, Celestine, Beissbarth, Jemima, Bialasiewicz, Seweryn, Binks, Michael, Cervin, Anders, Kirkham, Lea-Ann S., Lemon, Katherine P., Slack, Mary P.E. and Smith-Vaughan, Heidi C. (2020). Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures. International Journal of Pediatric Otorhinolaryngology, 130 (Supp. 1) 109836, 109836. doi: 10.1016/j.ijporl.2019.109836

Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

2020

Journal Article

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

Fokkens, W. J., Lund, V. J., Hopkins, C., Hellings, P. W., Kern, R., Reitsma, S., Toppila-Salmi, S., Bernal-Sprekelsen, M., Mullol, J., Alobid, I., Terezinha Anselmo-Lima, W., Bachert, C., Baroody, F., von Buchwald, C., Cervin, A., Cohen, N., Constantinidis, J., De Gabory, L., Desrosiers, M., Diamant, Z., Douglas, R. G., Gevaert, P. H., Hafner, A., Harvey, R. J., Joos, G. F., Kalogjera, L., Knill, A., Kocks, J. H., Landis, B. N. ... Stjarne, P. (2020). European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology, 58 (S29), 1-464. doi: 10.4193/Rhin20.600

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

2019

Journal Article

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials

Bachert, Claus, Han, Joseph K, Desrosiers, Martin, Hellings, Peter W, Amin, Nikhil, Lee, Stella E, Mullol, Joaquim, Greos, Leon S, Bosso, John V, Laidlaw, Tanya M, Cervin, Anders U, Maspero, Jorge F, Hopkins, Claire, Olze, Heidi, Canonica, G Walter, Paggiaro, Pierluigi, Cho, Seong H, Fokkens, Wytske J, Fujieda, Shigeharu, Zhang, Mei, Lu, Xin, Fan, Chunpeng, Draikiwicz, Steven, Kamat, Siddhesh A, Khan, Asif, Pirozzi, Gianluca, Patel, Naimish, Graham, Neil M H, Ruddy, Marcella ... Mannent, Leda P (2019). Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. The Lancet, 394 (10209), 1638-1650. doi: 10.1016/S0140-6736(19)31881-1

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials

2019

Journal Article

Oral corticosteroids for painful acute otitis externa (swimmer's ear): a triple-blind randomised controlled trial

Balch, Graeme, Heal, Clare, Cervin, Anders and Gunnarsson, Ronny (2019). Oral corticosteroids for painful acute otitis externa (swimmer's ear): a triple-blind randomised controlled trial. Australian Journal of General Practice, 48 (8), 565-572. doi: 10.31128/AJGP-12-18-4795

Oral corticosteroids for painful acute otitis externa (swimmer's ear): a triple-blind randomised controlled trial

2019

Journal Article

Inflammation and endotyping in chronic rhinosinusitis — a paradigm shift

Ahern, Sinead and Cervin, Anders (2019). Inflammation and endotyping in chronic rhinosinusitis — a paradigm shift. Medicina, 55 (4) 95, 95. doi: 10.3390/medicina55040095

Inflammation and endotyping in chronic rhinosinusitis — a paradigm shift

2019

Journal Article

Trends in the quality & quantity of otorhinolaryngology research in Australia: 1989-2018

Bell-Allen, Nicholas, Cervin, Anders and Vasani, Sarju (2019). Trends in the quality & quantity of otorhinolaryngology research in Australia: 1989-2018. Australian Journal of Otolaryngology, 2 (April) 12. doi: 10.21037/ajo.2019.03.02

Trends in the quality & quantity of otorhinolaryngology research in Australia: 1989-2018

Funding

Current funding

  • 2021 - 2025
    Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2020 - 2024
    Development of Phage Therapy to Combat Chronic Otitis Media in Indigenous Children
    NHMRC IDEAS Grants
    Open grant
  • 2017 - 2027
    Garnett Passe and Rodney Williams Memorial Foundation Chair in Otorhinolaryngology, Head and Neck Surgery
    Garnett Passe/Rodney Williams Memorial Foundation
    Open grant

Past funding

  • 2015 - 2019
    Microbiota of the human sinuses: Its role in health and disease
    Garnett Passe/Rodney Williams Memorial Foundation
    Open grant
  • 2015
    The role of the bacterial, fungal and viral sinus microbiome in chronic rhinosinusitis patients
    Royal Brisbane and Women's Hospital
    Open grant

Supervision

Availability

Honorary Professor Anders Cervin is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Probiotic treatment of Chronic Rhinosinusits

    The overall aim of the project is to improve quality of life in patients suffering from Chronic RhinoSinusitis (CRS). Specifically by manipulating mucosal immunology and reducing the load of microbial pathogens in CRS by topical administration of probiotic bacterial strains. You will work in a stimulating environment in close relationship with patients, ENT surgeons, microbiologists and other researchers. The project have international collaborators in the Netherlands and Sweden. The project is truly translational you will acquire skills in clinical trials (GCP), as well as gaining laboratory experience in microbiology and cytokine analysis.

Supervision history

Current supervision

  • Master Philosophy

    Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial

    Principal Advisor

    Other advisors: Dr Diane Maresco-Pennisi

Completed supervision

Media

Enquiries

Contact Honorary Professor Anders Cervin directly for media enquiries about:

  • sinusitis

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