Overview
Background
Dr Kieran O'Brien is a Siemens Healthcare Adjunct Research Fellow at the Centre for Advanced Imaging. He completed his Bachelor of Biomedical Engineering (Honours, 2005) and PhD in Bioengineering from the University of Auckland in 2009. After being awarded his PhD Kieran worked in Postdoctoral positions at the University of Auckland and the University of Geneva Centre d'Imagerie BioMédicale before joining Siemens as a Senior Scientist in 2013.
His research interests are include improving RF pulses at high field (≥3T) to overcome imaging inhomogeneity and B1 limitations for Neuro, MSK and Cardiac applications; bi-exponential diffusion imaging; and, phase imaging for quantitative susceptibility mapping and measuring motion.
Availability
- Dr Kieran O'Brien is:
- Available for supervision
Fields of research
Research impacts
Kieran has developed expertise as a sequence and image reconstruction software programmer for Siemens MR Scanners; developing, implementing and validating new advanced image acquisition and reconstruction techniques that overcome clinical and physical problems into commercial products. He has been responsible for leading the management of sequence projects to translate basic research from the lab on to Siemens scanners as software products that can be distributed to researchers worldwide. Of particular note is his involvement in the upgrade and development of the software for the new 7T Terra clinical system.
Works
Search Professor Kieran O'Brien’s works on UQ eSpace
2016
Conference Publication
Contribution of cortical layer cytoarchitecture to quantitative susceptibility mapping
Sood, Surabhi, Urriola, Javier, Reutens, David C., Bollmann, Steffen, O'Brien, Kieran, Barth, Markus and Vegh, Viktor (2016). Contribution of cortical layer cytoarchitecture to quantitative susceptibility mapping. Organisation of the Human Brain Mapping, Geneva, Switzerland, 26-30 June, 2016.
2016
Conference Publication
Selective combination of MRI phase images
Vegh, Viktor, O'Brien, Kieran, Reutens, David C., Bollmann, Steffen and Barth, Markus (2016). Selective combination of MRI phase images. International Symposium on Magnetic Resonance in Medicine, Singapore, 7-13 May, 2016.
2015
Journal Article
Selective channel combination of MRI signal phase
Vegh, Viktor, O'Brien, Kieran, Barth, Markus and Reutens, David C. (2015). Selective channel combination of MRI signal phase. Magnetic Resonance in Medicine, 76 (5), 1469-1477. doi: 10.1002/mrm.26057
2015
Journal Article
Functional mapping of the human visual cortex with intravoxel incoherent motion MRI
Federau, Christian, O'Brien, Kieran, Birbaumer, Adrien, Meuli, Reto, Hagmann, Patric and Maeder, Philippe (2015). Functional mapping of the human visual cortex with intravoxel incoherent motion MRI. PLoS ONE, 10 (2) e0117706, e0117706. doi: 10.1371/journal.pone.0117706
2015
Journal Article
Increased brain perfusion contrast with T2-prepared intravoxel incoherent motion (T2prep IVIM) MRI
Federau, Christian and O'Brien, Kieran (2015). Increased brain perfusion contrast with T2-prepared intravoxel incoherent motion (T2prep IVIM) MRI. NMR in Biomedicine, 28 (1), 9-16. doi: 10.1002/nbm.3223
2015
Conference Publication
In-vivo measurements of axon radius and density in the corpus callosum using anomalous diffusion from diffusion MRI
Yu, Qiang, Vegh, Viktor, O'Brien, Kieran, Feiweier, Thorsten and Reutens, David C. (2015). In-vivo measurements of axon radius and density in the corpus callosum using anomalous diffusion from diffusion MRI. International Symposium on Magnetic Resonance in Medicine, Toronto, Canada, 30 May - 5 June 2015. ISMRM.
2014
Journal Article
Dielectric pads and low-B1+ adiabatic pulses: complementary techniques to optimize structural T1w whole-brain MP2RAGE scans at 7 tesla
O'Brien, Kieran R., Magill, Arthur W., Delacoste, Jean, Marques, Jose P., Kober, Tobias, Fautz, Hans-Peter, Lazeyras, Francois and Krueger, Gunnar (2014). Dielectric pads and low-B1+ adiabatic pulses: complementary techniques to optimize structural T1w whole-brain MP2RAGE scans at 7 tesla. Journal of Magnetic Resonance Imaging, 40 (4), 804-812. doi: 10.1002/jmri.24435
2014
Journal Article
Decline of fiber tract integrity over the adult age range: a diffusion spectrum imaging study
Teipel, Stefan J., Lerche, Maximilian, Kilimann, Ingo, O'Brien, Kieran, Grothe, Michel, Meyer, Peter, Li, Xingfeng, Saenger, Peter and Hauenstein, Karlheinz (2014). Decline of fiber tract integrity over the adult age range: a diffusion spectrum imaging study. Journal of Magnetic Resonance Imaging, 40 (2), 348-359. doi: 10.1002/jmri.24420
2014
Journal Article
Intravoxel incoherent motion perfusion imaging in acute stroke: initial clinical experience
Federau, C., Sumer, S., Becce, F., Maeder, P., O'Brien, K., Meuli, R. and Wintermark, M. (2014). Intravoxel incoherent motion perfusion imaging in acute stroke: initial clinical experience. Neuroradiology, 56 (8), 629-635. doi: 10.1007/s00234-014-1370-y
2014
Journal Article
Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models
Kunz, Nicolas, Zhang, Hui, Vasung, Lana, O'Brien, Kieran R., Assaf, Yaniv, Lazeyras, Francois, Alexander, Daniel C. and Hueppi, Petra S. (2014). Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models. NeuroImage, 96, 288-299. doi: 10.1016/j.neuroimage.2014.03.057
2014
Journal Article
Robust T1-weighted structural brain imaging and morphometry at 7T using MP2RAGE
O'Brien, Kieran R., Kober, Tobias, Hagmann, Patric, Maeder, Philippe, Marques, Jose, Lazeyras, Francois, Krueger, Gunnar and Roche, Alexis (2014). Robust T1-weighted structural brain imaging and morphometry at 7T using MP2RAGE. PLoS ONE, 9 (6) e99676, e99676. doi: 10.1371/journal.pone.0099676
2014
Journal Article
Are glutamate and lactate increases ubiquitous to physiological activation? A H-1 functional MR spectroscopy study during motor activation in human brain at 7 Tesla
Schaller, Benoit, Xin, Lijing, O'Brien, Kieran, Magill, Arthur W. and Gruetter, Rolf (2014). Are glutamate and lactate increases ubiquitous to physiological activation? A H-1 functional MR spectroscopy study during motor activation in human brain at 7 Tesla. NeuroImage, 93 (Part 1), 138-145. doi: 10.1016/j.neuroimage.2014.02.016
2014
Journal Article
Improving T2-weighted imaging at high field through the use of kT-points
Eggenschwiler, Florent, O'Brien, Kieran R., Gruetter, Rolf and Marques, Jose P. (2014). Improving T2-weighted imaging at high field through the use of kT-points. Magnetic Resonance in Medicine, 71 (4), 1478-1488. doi: 10.1002/mrm.24805
2014
Journal Article
Measuring brain perfusion with intravoxel incoherent motion (IVIM): initial clinical experience
Federau, Christian, O'Brien, Kieran, Meuli, Reto, Hagmann, Patric and Maeder, Philippe (2014). Measuring brain perfusion with intravoxel incoherent motion (IVIM): initial clinical experience. Journal of Magnetic Resonance Imaging, 39 (3), 624-632. doi: 10.1002/jmri.24195
2014
Journal Article
Perfusion measurement in brain gliomas with intravoxel incoherent motion MRI
Federau, C., Meuli, R., O'Brien, K., Maeder, P. and Hagmann, P. (2014). Perfusion measurement in brain gliomas with intravoxel incoherent motion MRI. American Journal of Neuroradiology, 35 (2), 256-262. doi: 10.3174/ajnr.A3686
2014
Journal Article
Quantification of aortic flow by phase-contrast magnetic resonance in patients with bicuspid aortic valve
Muzzarelli, S., Monney, P., O'Brien, K., Faletra, F., Moccetti, T., Vogt, P. and Schwitter, J. (2014). Quantification of aortic flow by phase-contrast magnetic resonance in patients with bicuspid aortic valve. European Heart Journal Cardiovascular Imaging, 15 (1) O37, 77-84. doi: 10.1093/ehjci/jet129
2014
Conference Publication
Simulation-based evaluation of susceptibility distortion correction methods in diffusion mri for connectivity analysis
Esteban, Oscar, Daducci, Alessandro, Caruyer, Emmanuel, O'Brien, Kieran, Ledesma-Carbayo, María J., Bach-Cuadra, Meritxell and Santos, Andrés (2014). Simulation-based evaluation of susceptibility distortion correction methods in diffusion mri for connectivity analysis. 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014, Beijing, China, 29 April - 2 May 2014. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/ISBI.2014.6867976
2013
Journal Article
Dependence of brain intravoxel incoherent motion perfusion parameters on the cardiac cycle
Federau, Christian, Hagmann, Patric, Maeder, Philippe, Mueller, Markus, Meuli, Reto, Stuber, Matthias and O'Brien, Kieran (2013). Dependence of brain intravoxel incoherent motion perfusion parameters on the cardiac cycle. PLoS ONE, 8 (8) e72856, e72856. doi: 10.1371/journal.pone.0072856
2013
Journal Article
3-D residual eddy current field characterisation: applied to diffusion weighted magnetic resonance imaging
O'Brien, Kieran, Daducci, Alessandro, Kickler, Nils, Lazeyras, Francois, Gruetter, Rolf, Feiweier, Thorsten and Krueger, Gunnar (2013). 3-D residual eddy current field characterisation: applied to diffusion weighted magnetic resonance imaging. IEEE Transactions on Medical Imaging, 32 (8) 6514081, 1515-1525. doi: 10.1109/TMI.2013.2259249
2012
Journal Article
Quantitative measurement of brain perfusion with intravoxel incoherent motion MR imaging
Federau, Christian, Maeder, Philippe, O'Brien, Kieran, Browaeys, Patrick, Meuli, Reto and Hagmann, Patric (2012). Quantitative measurement of brain perfusion with intravoxel incoherent motion MR imaging. Radiology, 265 (3), 874-881. doi: 10.1148/radiol.12120584
Funding
Past funding
Supervision
Availability
- Dr Kieran O'Brien is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
AI in the detection and diagnosis of preclinical and early osteoarthritis
Associate Advisor
Other advisors: Associate Professor Craig Engstrom, Dr Shakes Chandra
-
Doctor Philosophy
Evaluating Magnetic Resonance Spectroscopy and Spectroscopic Imaging Techniques in Motor Neuron Disease at 3T and 7T
Associate Advisor
Other advisors: Dr Thomas Shaw, Professor Markus Barth
Completed supervision
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2025
Doctor Philosophy
Towards QSM validation: reference measurement, doping materials, and anthropomorphic phantoms
Associate Advisor
Other advisors: Dr Monique Tourell, Professor Markus Barth
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2023
Doctor Philosophy
Automated Quantitative Susceptibility Mapping for Clinical Applications
Associate Advisor
Other advisors: Professor Markus Barth, Dr Monique Tourell, Dr Steffen Bollmann
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2021
Doctor Philosophy
Sequence Development to Improve Image Quality for T2- and Diffusion Weighted Imaging at 7T
Associate Advisor
Other advisors: Dr Steffen Bollmann, Professor Markus Barth
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2019
Doctor Philosophy
Radiofrequency safety and shimming near metal hip prostheses at high and ultra-high field MRI
Associate Advisor
Other advisors: Professor Feng Liu, Professor Markus Barth, Emeritus Professor Stuart Crozier
Media
Enquiries
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