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2026 Journal Article Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial InfarctionHume, Robert, Warwick, Jessica, Shim, Woo Jun, Malecki, Cassandra, Li, Mengbo, Harney, Dylan, Slaughter, Eugene, Wang, XiaoSuo, Nguyen, Lisa, Cole, Louise, Edelman, James, Rashid, Fairooj, Houlahan, Callum, Gao, Antony, Ferguson, Angela, Chong, James, Larance, Mark, O'Sullivan, John, Palpant, Nathan, Bannon, Paul and Lal, Sean (2026). Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction. Journal of Molecular and Cellular Cardiology Plus, 15 100505, 100505. doi: 10.1016/j.jmccpl.2025.100505 |
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2026 Journal Article Hi1a delivered in various modes reduces myocardial infarct size in miceWu, Jianxin, Gao, Ling, Villanueva, Jeanette, Doyle, Aoife, Dutta, Sanjay, Joshi, Yashutosh, MacLean, Campbell, Kesteven, Scott, King, Glenn, Palpant, Nathan, Feneley, Michael, Iismaa, Siiri, Graham, Robert and Macdonald, Peter (2026). Hi1a delivered in various modes reduces myocardial infarct size in mice. Journal of Molecular and Cellular Cardiology Plus, 15 100753, 100753. doi: 10.1016/j.jmccpl.2025.100753 |
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2026 Journal Article Nanopatterned cell sheet assembly of biomimetic cardiac laminae for modeling structure-function relationshipsJiao, Alex, Macadangdang, Jesse, Kim, Jinsung, Moerk, Charles Travis, Palpant, Nathan J., Mengsteab, Paulos Y., Park, Hyeon-Cheol, Murry, Charles E. and Kim, Deok-Ho (2026). Nanopatterned cell sheet assembly of biomimetic cardiac laminae for modeling structure-function relationships. Biomaterials Research, 30 0339, 1-12. doi: 10.34133/bmr.0339 |
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2025 Journal Article Epigenomics and transcriptomics profiles of developing zebrafish heart cellsChahal, Gulrez, Eichenlaub, Michael P., Tondl, Markus, Pawlak, Michał, Mohenska, Monika, Grimm, Lin, Bottrell, Lauren, Drvodelic, Mark, Alaei, Sara, Hallab, Jeannette, Waylen, Lisa N., Polo, Jose M., Blanpain, Cédric, Palpant, Nathan, Rossello, Fernando J., Änkö, Minna-Liisa, Currie, Peter D., Hogan, Benjamin M., Winata, Cecilia, Salimova, Ekaterina, Nim, Hieu T. and Ramialison, Mirana (2025). Epigenomics and transcriptomics profiles of developing zebrafish heart cells. Scientific Data, 12 (1) 1620, 1-10. doi: 10.1038/s41597-025-05895-9 |
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2025 Journal Article A pluripotent stem cell atlas of multilineage differentiationShen, Sophie, Werner, Tessa, Chiu, Han Sheng, Chen, Xiaoli, Nguyen, Quan and Palpant, Nathan J. (2025). A pluripotent stem cell atlas of multilineage differentiation. Scientific Data, 12 (1) 1238, 1238. doi: 10.1038/s41597-025-05549-w |
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2025 Journal Article Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetesCao, Yuanzhao, Redd, Meredith, Outhwaite, Jennifer, Mizikovsky, Dalia, Shim, Woo Jun, Fang, Chen, Wu, Zhixuan, Daygon, Dara, Stark, Terra, Palfreyman, Robin, Chiu, Han Sheng, Tan, Clarissa, Thomas, Ulrich, Dragicevic, Elena, Sng, Julian, Barrett, Helen, Dorey, Emily, Shah, Sonia, Short, Kirsty and Palpant, Nathan J. (2025). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. doi: 10.1101/2025.01.29.635173 |
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2025 Journal Article Human hearts intrinsically increase cardiomyocyte mitosis after myocardial infarctionHume, Robert D., Warwick, Jessica, Shim, Woo Jun, Malecki, Cassandra, Li, Mengbo, Seth, Lakshay, Harney, Dylan, Dagher, Julien, Lum, Trina, Tierney, Geraldine, Cooper, Wendy, Slaughter, Eugene, Wang, Xiaosuo, Nguyen, Lisa, Cole, Louise, Edelman, James, Rashid, Fairooj, Houlahan, Callum, Gao, Antony, Ferguson, Angela L., Chong, James J.H., Larance, Mark, O’Sullivan, John, Palpant, Nathan J., Bannon, Paul and Lal, Sean (2025). Human hearts intrinsically increase cardiomyocyte mitosis after myocardial infarction. Circulation Research, 138 (2) e327486, 367-382. doi: 10.1161/circresaha.125.327486 |
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2025 Journal Article TRIAGE: an R package for regulatory gene analysisZhao, Qiongyi, Shim, Woo Jun, Sun, Yuliangzi, Sinniah, Enakshi, Shen, Sophie, Boden, Mikael and Palpant, Nathan J. (2025). TRIAGE: an R package for regulatory gene analysis. Briefings in Bioinformatics, 26 (1) bbaf004, 1-13. doi: 10.1093/bib/bbaf004 |
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2024 Journal Article Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionSinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z |
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Featured 2024 Journal Article A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cellsChow, Chris Siu Yeung, Negi, Sumedha, Bao, Shaine, Fang, Chen, Hudson, James, Shim, Woo Jun, Yuanzhao Cao and Palpant, Nathan (2024). A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cells. doi: 10.1101/2024.09.04.611313 |
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2024 Journal Article High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venomsKramer, Simon, Kotapati, Charan, Cao, Yuanzhao, Fry, Bryan G., Palpant, Nathan J., King, Glenn F. and Cardoso, Fernanda C. (2024). High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms. Toxicon: X, 21 100184, 100184. doi: 10.1016/j.toxcx.2024.100184 |
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2024 Journal Article Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmiasSelvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3 |
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2023 Journal Article A village in a dish model system for population-scale hiPSC studiesNeavin, Drew R., Steinmann, Angela M., Farbehi, Nona, Chiu, Han Sheng, Daniszewski, Maciej S., Arora, Himanshi, Bermudez, Yasmin, Moutinho, Cátia, Chan, Chia-Ling, Bax, Monique, Tyebally, Mubarika, Gnanasambandapillai, Vikkitharan, Lam, Chuan E., Nguyen, Uyen, Hernández, Damián, Lidgerwood, Grace E., Graham, Robert M., Hewitt, Alex W., Pébay, Alice, Palpant, Nathan J. and Powell, Joseph E. (2023). A village in a dish model system for population-scale hiPSC studies. Nature Communications, 14 (1) 3240, 1-12. doi: 10.1038/s41467-023-38704-1 |
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2023 Journal Article Vascular cells improve functionality of human cardiac organoidsVoges, Holly K., Foster, Simon R., Reynolds, Liam, Parker, Benjamin L., Devilée, Lynn, Quaife-Ryan, Gregory A., Fortuna, Patrick R.J., Mathieson, Ellen, Fitzsimmons, Rebecca, Lor, Mary, Batho, Christopher, Reid, Janice, Pocock, Mark, Friedman, Clayton E., Mizikovsky, Dalia, Francois, Mathias, Palpant, Nathan J., Needham, Elise J., Peralta, Marina, Monte-Nieto, Gonzalo del, Jones, Lynelle K., Smyth, Ian M., Mehdiabadi, Neda R., Bolk, Francesca, Janbandhu, Vaibhao, Yao, Ernestene, Harvey, Richard P., Chong, James J.H., Elliott, David A. ... Hudson, James E. (2023). Vascular cells improve functionality of human cardiac organoids. Cell Reports, 42 (5) 112322, 1-22. doi: 10.1016/j.celrep.2023.112322 |
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2023 Journal Article New drug targets and preclinical modelling recommendations for treating acute myocardial infarctionCao, Yuanzhao, Redd, Meredith A., Fang, Chen, Mizikovsky, Dalia, Li, Xichun, Macdonald, Peter S., King, Glenn F. and Palpant, Nathan J. (2023). New drug targets and preclinical modelling recommendations for treating acute myocardial infarction. Heart, Lung and Circulation, 32 (7), 852-869. doi: 10.1016/j.hlc.2022.12.015 |
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2023 Journal Article PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial InfarctionHume, Robert D., Deshmukh, Tejas, Doan, Tram, Shim, Woo Jun, Kanagalingam, Shaan, Tallapragada, Vikram, Rashid, Fairooj, Marcuello, Maria, Blessing, Daniel, Selvakumar, Dinesh, Raguram, Kalyan, Pathan, Faraz, Graham, Dinny, Ounzain, Samir, Kizana, Eddy, Harvey, Richard P., Palpant, Nathan J. and Chong, James J.H. (2023). PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction. JACC: Basic to Translational Science, 8 (6), 658-674. doi: 10.1016/j.jacbts.2022.11.006 |
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2023 Journal Article Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiationAlavattam, Kris G., Mitzelfelt, Katie A., Bonora, Giancarlo, Fields, Paul A., Yang, Xiulan, Chiu, Han Sheng, Pabon, Lil, Bertero, Alessandro, Palpant, Nathan J., Noble, William S. and Murry, Charles E. (2023). Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation. Stem Cell Reports, 18 (1), 159-174. doi: 10.1016/j.stemcr.2022.11.003 |
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2023 Journal Article A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specificationPlaisance, Isabelle, Chouvardas, Panagiotis, Sun, Yuliangzi, Nemir, Mohamed, Aghagolzadeh, Parisa, Aminfar, Farhang, Shen, Sophie, Shim, Woo Jun, Rochais, Francesca, Johnson, Rory, Palpant, Nathan and Pedrazzini, Thierry (2023). A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification. Cardiovascular Research, 119 (6), 1361-1376. doi: 10.1093/cvr/cvac191 |
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2022 Journal Article The ins and outs of cellular pH during cardiac ischemiaCao, Yuanzhao and Palpant, Nathan J. (2022). The ins and outs of cellular pH during cardiac ischemia. Journal of Molecular and Cellular Cardiology, 174, 133-134. doi: 10.1016/j.yjmcc.2022.12.004 |
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2022 Journal Article Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated CardiomyopathyMehdiabadi, Neda R., Boon Sim, Choon, Phipson, Belinda, Kalathur, Ravi K.R., Sun, Yuliangzi, Vivien, Celine J., ter Huurne, Menno, Piers, Adam T., Hudson, James E., Oshlack, Alicia, Weintraub, Robert G., Konstantinov, Igor E., Palpant, Nathan J., Elliott, David A. and Porrello, Enzo R. (2022). Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy. Circulation, 146 (14), 1105-1108. doi: 10.1161/circulationaha.121.057763 |
