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2019

Other Outputs

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

2019

Journal Article

Identification of common genetic risk variants for autism spectrum disorder

Grove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel ... Børglum, Anders D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51 (3), 431-444. doi: 10.1038/s41588-019-0344-8

Identification of common genetic risk variants for autism spectrum disorder

2019

Journal Article

Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

Lakhani, Chirag M., Tierney, Braden T., Manrai, Arjun K., Yang, Jian, Visscher, Peter M. and Patel, Chirag J. (2019). Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nature Genetics, 51 (4), 764-765. doi: 10.1038/s41588-019-0377-z

Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

2019

Other Outputs

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

2019

Journal Article

Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits

Visscher, Peter M. and Bruce Walsh, J. (2019). Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits. International Journal of Epidemiology, 48 (1), 10-12. doi: 10.1093/ije/dyx129

Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits

2019

Journal Article

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Haworth, Simon, Shapland, Chin Yang, Hayward, Caroline, Prins, Bram P., Felix, Janine F., Medina-Gomez, Carolina, Rivadeneira, Fernando, Wang, Carol, Ahluwalia, Tarunveer S., Vrijheid, Martine, Guxens, Mònica, Sunyer, Jordi, Tachmazidou, Ioanna, Walter, Klaudia, Iotchkova, Valentina, Jackson, Andrew, Cleal, Louise, Huffmann, Jennifer, Min, Josine L., Sass, Lærke, Timmers, Paul R. H. J., Turki, Saeed Al, Anderson, Carl A., Anney, Richard, Antony, Dinu, Artigas, María Soler, Ayub, Muhammad, Bala, Senduran, Barrett, Jeffrey C. ... St Pourcain, Beate (2019). Low-frequency variation in TP53 has large effects on head circumference and intracranial volume. Nature Communications, 10 (1) 357. doi: 10.1038/s41467-018-07863-x

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

2019

Other Outputs

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961

Improved polygenic prediction by Bayesian multiple regression on summary statistics

2019

Journal Article

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

Lakhani, Chirag M., Tierney, Braden T., Manrai, Arjun K., Yang, Jian, Visscher, Peter M. and Patel, Chirag J. (2019). Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nature Genetics, 51 (2), 327-334. doi: 10.1038/s41588-018-0313-7

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

2019

Journal Article

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

Pulit, Sara L., Stoneman, Charli, Morris, Andrew P., Wood, Andrew R., Glastonbury, Craig A., Tyrrell, Jessica, Yengo, Loïc, Ferreira, Teresa, Marouli, Eirini, Ji, Yingjie, Yang, Jian, Jones, Samuel, Beaumont, Robin, Croteau-Chonka, Damien C., Winkler, Thomas W., Consortium, Giant, Hattersley, Andrew T., Loos, Ruth J F, Hirschhorn, Joel N., Visscher, Peter M., Frayling, Timothy M., Yaghootkar, Hanieh and Lindgren, Cecilia M. (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Human Molecular Genetics, 28 (1), 166-174. doi: 10.1093/hmg/ddy327

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

2019

Journal Article

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hinds, David A., Hromatka, Bethann S., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Benjamin, Daniel J. (2019). Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4). Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0469-9

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

2019

Conference Publication

Equivalence of LD-score regression and individual-level-data methods

de Vlaming, R., Johannesson, M., Magnusson, P. K. E., Ikram, M. A. and Visscher, P. M. (2019). Equivalence of LD-score regression and individual-level-data methods. 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, Italy, 16-19 June 2018 . London, United Kingdom: Nature Publishing Group.

Equivalence of LD-score regression and individual-level-data methods

2019

Journal Article

A polygenic resilience score moderates the genetic risk for schizophrenia

Hess, Jonathan L., Tylee, Daniel S., Mattheisen, Manuel, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Andreassen, Ole A, Arranz, Maria J, Bacanu, Silviu A, Bakker, Steven, Band, Gavin, Barroso, Ines, Begemann, Martin, Bellenguez, Céline, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Bramon, Elvira, Brown, Matthew A ... Glatt, Stephen J. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry, 26 (3), 800-815. doi: 10.1038/s41380-019-0463-8

A polygenic resilience score moderates the genetic risk for schizophrenia

2019

Journal Article

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

Foo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

2019

Journal Article

The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA

Vennin, Emmanuelle, Bouton, Anthony, Bourillot, Raphael, Pace, Aurelie, Roche, Adeline, Brayard, Arnaud, Thomazo, Christophe, Virgone, Aurelien, Gaucher, Eric C., Desaubliaux, Guy and Visscher, Pieter T. (2019). The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA. Sedimentology, 66 (1), 165-204. doi: 10.1111/sed.12499

The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA

2019

Conference Publication

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

Couvy-Duchesne, Baptiste, Strike, Lachlan, Zhang, Futao, Wray, Naomi, Wright, Margaret, Visscher, Peter and Yang, Jian (2019). Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.140

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

2019

Conference Publication

Effects of assortative mating on estimates of SNP heritability

Keller, Matthew, de Candia, Teresa, Jones, Matt, Tahmasbi, Rasool, Evans, Luke, Evans, David, Eaves, Lindon, Yang, Jian, Visscher, Peter and Goddard, Mike (2019). Effects of assortative mating on estimates of SNP heritability. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.016

Effects of assortative mating on estimates of SNP heritability

2019

Journal Article

Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hinds, David A., Hromatka, Bethann S., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Benjamin, Daniel J. (2019). Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4). Nature Genetics, 51 (7), 1190-1190. doi: 10.1038/s41588-019-0444-5

Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

2019

Conference Publication

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

2019

Conference Publication

Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches

Evans, Luke, Border, Richard, du Pont, Alta, Friedman, Naomi, Johnson, Emma, Yang, Jian, Visscher, Peter and Keller, Matthew (2019). Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2018.08.032

Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches

2018

Other Outputs

Genetic analyses of medication-use and implications for precision medicine

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049

Genetic analyses of medication-use and implications for precision medicine