2019 Other Outputs Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disordersByrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899 |
2019 Journal Article Identification of common genetic risk variants for autism spectrum disorderGrove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel ... Børglum, Anders D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51 (3), 431-444. doi: 10.1038/s41588-019-0344-8 |
2019 Journal Article Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypesLakhani, Chirag M., Tierney, Braden T., Manrai, Arjun K., Yang, Jian, Visscher, Peter M. and Patel, Chirag J. (2019). Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nature Genetics, 51 (4), 764-765. doi: 10.1038/s41588-019-0377-z |
2019 Other Outputs Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940 |
2019 Journal Article Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traitsVisscher, Peter M. and Bruce Walsh, J. (2019). Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits. International Journal of Epidemiology, 48 (1), 10-12. doi: 10.1093/ije/dyx129 |
2019 Journal Article Low-frequency variation in TP53 has large effects on head circumference and intracranial volumeHaworth, Simon, Shapland, Chin Yang, Hayward, Caroline, Prins, Bram P., Felix, Janine F., Medina-Gomez, Carolina, Rivadeneira, Fernando, Wang, Carol, Ahluwalia, Tarunveer S., Vrijheid, Martine, Guxens, Mònica, Sunyer, Jordi, Tachmazidou, Ioanna, Walter, Klaudia, Iotchkova, Valentina, Jackson, Andrew, Cleal, Louise, Huffmann, Jennifer, Min, Josine L., Sass, Lærke, Timmers, Paul R. H. J., Turki, Saeed Al, Anderson, Carl A., Anney, Richard, Antony, Dinu, Artigas, María Soler, Ayub, Muhammad, Bala, Senduran, Barrett, Jeffrey C. ... St Pourcain, Beate (2019). Low-frequency variation in TP53 has large effects on head circumference and intracranial volume. Nature Communications, 10 (1) 357. doi: 10.1038/s41467-018-07863-x |
2019 Other Outputs Improved polygenic prediction by Bayesian multiple regression on summary statisticsLloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961 |
2019 Journal Article Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypesLakhani, Chirag M., Tierney, Braden T., Manrai, Arjun K., Yang, Jian, Visscher, Peter M. and Patel, Chirag J. (2019). Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nature Genetics, 51 (2), 327-334. doi: 10.1038/s41588-018-0313-7 |
2019 Journal Article Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestryPulit, Sara L., Stoneman, Charli, Morris, Andrew P., Wood, Andrew R., Glastonbury, Craig A., Tyrrell, Jessica, Yengo, Loïc, Ferreira, Teresa, Marouli, Eirini, Ji, Yingjie, Yang, Jian, Jones, Samuel, Beaumont, Robin, Croteau-Chonka, Damien C., Winkler, Thomas W., Consortium, Giant, Hattersley, Andrew T., Loos, Ruth J F, Hirschhorn, Joel N., Visscher, Peter M., Frayling, Timothy M., Yaghootkar, Hanieh and Lindgren, Cecilia M. (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Human Molecular Genetics, 28 (1), 166-174. doi: 10.1093/hmg/ddy327 |
2019 Journal Article Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hinds, David A., Hromatka, Bethann S., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Benjamin, Daniel J. (2019). Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4). Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0469-9 |
2019 Conference Publication Equivalence of LD-score regression and individual-level-data methodsde Vlaming, R., Johannesson, M., Magnusson, P. K. E., Ikram, M. A. and Visscher, P. M. (2019). Equivalence of LD-score regression and individual-level-data methods. 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, Italy, 16-19 June 2018 . London, United Kingdom: Nature Publishing Group. |
2019 Journal Article A polygenic resilience score moderates the genetic risk for schizophreniaHess, Jonathan L., Tylee, Daniel S., Mattheisen, Manuel, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Andreassen, Ole A, Arranz, Maria J, Bacanu, Silviu A, Bakker, Steven, Band, Gavin, Barroso, Ines, Begemann, Martin, Bellenguez, Céline, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Bramon, Elvira, Brown, Matthew A ... Glatt, Stephen J. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry, 26 (3), 800-815. doi: 10.1038/s41380-019-0463-8 |
2019 Journal Article Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapyFoo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700 |
2019 Journal Article The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USAVennin, Emmanuelle, Bouton, Anthony, Bourillot, Raphael, Pace, Aurelie, Roche, Adeline, Brayard, Arnaud, Thomazo, Christophe, Virgone, Aurelien, Gaucher, Eric C., Desaubliaux, Guy and Visscher, Pieter T. (2019). The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA. Sedimentology, 66 (1), 165-204. doi: 10.1111/sed.12499 |
2019 Conference Publication Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traitsCouvy-Duchesne, Baptiste, Strike, Lachlan, Zhang, Futao, Wray, Naomi, Wright, Margaret, Visscher, Peter and Yang, Jian (2019). Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.140 |
2019 Conference Publication Effects of assortative mating on estimates of SNP heritabilityKeller, Matthew, de Candia, Teresa, Jones, Matt, Tahmasbi, Rasool, Evans, Luke, Evans, David, Eaves, Lindon, Yang, Jian, Visscher, Peter and Goddard, Mike (2019). Effects of assortative mating on estimates of SNP heritability. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.016 |
2019 Journal Article Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hinds, David A., Hromatka, Bethann S., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Benjamin, Daniel J. (2019). Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4). Nature Genetics, 51 (7), 1190-1190. doi: 10.1038/s41588-019-0444-5 |
2019 Conference Publication Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothersGratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167 |
2019 Conference Publication Exploring the genetic architecture of psychiatric disorders using partitioned heritability approachesEvans, Luke, Border, Richard, du Pont, Alta, Friedman, Naomi, Johnson, Emma, Yang, Jian, Visscher, Peter and Keller, Matthew (2019). Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2018.08.032 |
2018 Other Outputs Genetic analyses of medication-use and implications for precision medicineWu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049 |