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2019

Journal Article

A polygenic resilience score moderates the genetic risk for schizophrenia

Hess, Jonathan L., Tylee, Daniel S., Mattheisen, Manuel, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Andreassen, Ole A, Arranz, Maria J, Bacanu, Silviu A, Bakker, Steven, Band, Gavin, Barroso, Ines, Begemann, Martin, Bellenguez, Céline, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Bramon, Elvira, Brown, Matthew A ... Glatt, Stephen J. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry, 26 (3), 800-815. doi: 10.1038/s41380-019-0463-8

A polygenic resilience score moderates the genetic risk for schizophrenia

2019

Journal Article

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

Foo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

2019

Conference Publication

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

Couvy-Duchesne, Baptiste, Strike, Lachlan, Zhang, Futao, Wray, Naomi, Wright, Margaret, Visscher, Peter and Yang, Jian (2019). Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.140

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

2019

Conference Publication

Effects of assortative mating on estimates of SNP heritability

Keller, Matthew, de Candia, Teresa, Jones, Matt, Tahmasbi, Rasool, Evans, Luke, Evans, David, Eaves, Lindon, Yang, Jian, Visscher, Peter and Goddard, Mike (2019). Effects of assortative mating on estimates of SNP heritability. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.016

Effects of assortative mating on estimates of SNP heritability

2019

Journal Article

The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA

Vennin, Emmanuelle, Bouton, Anthony, Bourillot, Raphael, Pace, Aurelie, Roche, Adeline, Brayard, Arnaud, Thomazo, Christophe, Virgone, Aurelien, Gaucher, Eric C., Desaubliaux, Guy and Visscher, Pieter T. (2019). The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA. Sedimentology, 66 (1), 165-204. doi: 10.1111/sed.12499

The lacustrine microbial carbonate factory of the successive Lake Bonneville and Great Salt Lake, Utah, USA

2019

Journal Article

Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hinds, David A., Hromatka, Bethann S., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Benjamin, Daniel J. (2019). Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4). Nature Genetics, 51 (7), 1190-1190. doi: 10.1038/s41588-019-0444-5

Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG (Nature Genetics, (2018), 50, 2, (229-237), 10.1038/s41588-017-0009-4)

2019

Conference Publication

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

2019

Conference Publication

Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches

Evans, Luke, Border, Richard, du Pont, Alta, Friedman, Naomi, Johnson, Emma, Yang, Jian, Visscher, Peter and Keller, Matthew (2019). Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2018.08.032

Exploring the genetic architecture of psychiatric disorders using partitioned heritability approaches

2018

Journal Article

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Yap, Chloe X., Sidorenko, Julia, Wu, Yang, Kemper, Kathryn E., Yang, Jian, Wray, Naomi R., Robinson, Matthew R. and Visscher, Peter M. (2018). Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. Nature Communications, 9 (1) 5407, 5407. doi: 10.1038/s41467-018-07862-y

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

2018

Journal Article

Identification of 55,000 replicated DNA methylation QTL

McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w

Identification of 55,000 replicated DNA methylation QTL

2018

Journal Article

Leveraging GWAS for complex traits to detect signatures of natural selection in humans

Guo, Jing, Yang, Jian and Visscher, Peter M. (2018). Leveraging GWAS for complex traits to detect signatures of natural selection in humans. Current Opinion in Genetics and Development, 53, 9-14. doi: 10.1016/j.gde.2018.05.012

Leveraging GWAS for complex traits to detect signatures of natural selection in humans

2018

Journal Article

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, Aleix, Adams, Mark J., Hayward, Caroline, Thomson, Pippa A., Porteous, David, Campbell, Archie, Smith, Blair H., Black, Corri, Padmanabhan, Sandosh, McIntosh, Andrew, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Sullivan, Patrick F. (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS ONE, 13 (12) e0209160, e0209160. doi: 10.1371/journal.pone.0209160

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

2018

Journal Article

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome

Yengo, Loic and Visscher, Peter M. (2018). Assortative mating on complex traits revisited: Double first cousins and the X-chromosome. Theoretical Population Biology, 124, 51-60. doi: 10.1016/j.tpb.2018.09.002

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome

2018

Journal Article

Imprint of assortative mating on the human genome

Yengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3

Imprint of assortative mating on the human genome

2018

Journal Article

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))

Yap, Chloe X., Sidorenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537)). Nature communications, 9 (1) 4953, 4953. doi: 10.1038/s41467-018-07400-w

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))

2018

Journal Article

Epigenetic signatures of starting and stopping smoking

McCartney, Daniel L., Stevenson, Anna J., Hillary, Robert F., Walker, Rosie M., Bermingham, Mairead L., Morris, Stewart W., Clarke, Toni-Kim, Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Visscher, Peter M., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J. and Marioni, Riccardo E. (2018). Epigenetic signatures of starting and stopping smoking. EBioMedicine, 37, 214-220. doi: 10.1016/j.ebiom.2018.10.051

Epigenetic signatures of starting and stopping smoking

2018

Journal Article

Disentangling the drivers of functional complexity at the metagenomic level in Shark Bay microbial mat microbiomes

Wong, Hon Lun, White, Richard Allen, Visscher, Pieter T., Charlesworth, James C., Vazquez-Campos, Xabier and Burns, Brendan P. (2018). Disentangling the drivers of functional complexity at the metagenomic level in Shark Bay microbial mat microbiomes. Isme Journal, 12 (11), 2619-2639. doi: 10.1038/s41396-018-0208-8

Disentangling the drivers of functional complexity at the metagenomic level in Shark Bay microbial mat microbiomes

2018

Journal Article

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Zhang, Qian, Marioni, Riccardo E., Robinson, Matthew R., Higham, Jon, Sproul, Duncan, Wray, Naomi R., Deary, Ian J., McRae, Allan F. and Visscher, Peter M. (2018). Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine, 10 (1) 75, 75. doi: 10.1186/s13073-018-0585-7

Genotype effects contribute to variation in longitudinal methylome patterns in older people

2018

Journal Article

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

Yengo, Loic, Sidorenko, Julia, Kemper, Kathryn E., Zheng, Zhili, Wood, Andrew R., Weedon, Michael N., Frayling, Timothy M., Hirschhorn, Joel, Yang, Jian and Visscher, Peter M. (2018). Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry. Human Molecular Genetics, 27 (20), 3641-3649. doi: 10.1093/hmg/ddy271

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

2018

Journal Article

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder