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2018 Journal Article Common disease is more complex than implied by the core gene omnigenic modelWray, Naomi R., Wijmenga, Cisca, Sullivan, Patrick F., Yang, Jian and Visscher, Peter M. (2018). Common disease is more complex than implied by the core gene omnigenic model. Cell, 173 (7), 1573-1580. doi: 10.1016/j.cell.2018.05.051 |
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2018 Journal Article Identifying gene targets for brain-related traits using transcriptomic and methylomic data from bloodQi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, eQTLGen Consortium, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications, 9 (1) 2282, 2282. doi: 10.1038/s41467-018-04558-1 |
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2018 Journal Article Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humansCuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M., Gaunt, Tom R., McRae, Allan, Visscher, Peter M., Montgomery, Grant W., Martin, Nicholas G., Hemani, Gibran, Suderman, Matthew, Relton, Caroline L., Davey Smith, George and Evans, David M. (2018). Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics, 27 (16), 2927-2939. doi: 10.1093/hmg/ddy206 |
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2018 Journal Article GWAS on family history of Alzheimer's diseaseMarioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6 |
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2018 Journal Article Erratum: evidence of directional and stabilizing selection in contemporary humans (Proceedings of the National Academy of Sciences of the United States of America (2017) 115 (151–156) DOI: 10.1073/pnas.1707227114)Sanjak, Jaleal S., Sidorenko, Julia, Robinson, Matthew R., Thornton, Kevin R. and Visscher, Peter M. (2018). Erratum: evidence of directional and stabilizing selection in contemporary humans (Proceedings of the National Academy of Sciences of the United States of America (2017) 115 (151–156) DOI: 10.1073/pnas.1707227114). Proceedings of the National Academy of Sciences of the United States of America, 115 (20). doi: 10.1073/pnas.1806837115 |
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2018 Journal Article Global genetic differentiation of complex traits shaped by natural selection in humansGuo, Jing, Wu, Yang, Zhu, Zhihong, Zheng, Zhili, Trzaskowski, Maciej, Zeng, Jian, Robinson, Matthew R., Visscher, Peter M. and Yang, Jian (2018). Global genetic differentiation of complex traits shaped by natural selection in humans. Nature Communications, 9 (1) 1865, 1865. doi: 10.1038/s41467-018-04191-y |
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2018 Journal Article Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressionWray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3 |
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2018 Journal Article Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traitsEvans, Luke M., Tahmasbi, Rasool, Vrieze, Scott I., Abecasis, Gonçalo R., Das, Sayantan, Gazal, Steven, Bjelland, Douglas W., de Candia, Teresa R., Haplotype Reference Consortium, Goddard, Michael E., Neale, Benjamin M., Yang, Jian, Visscher, Peter M. and Keller, Matthew C. (2018). Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits. Nature genetics, 50 (5), 737-745. doi: 10.1038/s41588-018-0108-x |
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2018 Journal Article Signatures of negative selection in the genetic architecture of human complex traitsZeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, McRae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics, 50 (5), 746-753. doi: 10.1038/s41588-018-0101-4 |
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2018 Journal Article Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)Hebert, Harry L., Shepherd, Bridget, Milburn, Keith, Veluchamy, Abirami, Meng, Weihua, Carr, Fiona, Donnelly, Louise A., Tavendale, Roger, Leese, Graham, Colhoun, Helen M., Dow, Ellie, Morris, Andrew D., Doney, Alexander S., Lang, Chim C., Pearson, Ewan R., Smith, Blair H. and Palmer, Colin N. A. (2018). Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS). International Journal of Epidemiology, 47 (2), 380-+. doi: 10.1093/ije/dyx140 |
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2018 Journal Article Narrow-sense heritability estimation of complex traits using identity-by-descent informationEvans, Luke M., Tahmasbi, Rasool, Jones, Matt, Vrieze, Scott I., Abecasis, Gonçalo R., Das, Sayantan, Bjelland, Douglas W., de Candia, Teresa R., Yang, Jian, Goddard, Michael E., Visscher, Peter M., Keller, Matthew C. and Haplotype Reference Consortium (2018). Narrow-sense heritability estimation of complex traits using identity-by-descent information. Heredity, 121 (6), 1-15. doi: 10.1038/s41437-018-0067-0 |
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2018 Journal Article A multi-trait Bayesian method for mapping QTL and genomic predictionKemper, Kathryn E., Bowman, Philip J., Hayes, Benjamin J., Visscher, Peter M. and Goddard, Michael E. (2018). A multi-trait Bayesian method for mapping QTL and genomic prediction. Genetics Selection Evolution, 50 (1) 10, 10. doi: 10.1186/s12711-018-0377-y |
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2018 Journal Article Improving genetic prediction by leveraging genetic correlations among human diseases and traitsMaier, Robert M, Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M, Stahl, Eli A, Ripke, Stephan, Wray, Naomi R, Yang, Jian, Visscher, Peter M and Robinson, Matthew R (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications, 9 (1) 989, 989. doi: 10.1038/s41467-017-02769-6 |
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2018 Journal Article Integrative analysis of omics summary data reveals putative mechanisms underlying complex traitsWu, Yang, Zeng, Jian, Zhang, Futao, Zhu, Zhihong, Qi, Ting, Zheng, Zhili, Lloyd-Jones, Luke R., Marioni, Riccardo E., Martin, Nicholas G., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications, 9 (918) 918, 918. doi: 10.1038/s41467-018-03371-0 |
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2018 Journal Article Reply to Kardos et al.: estimation of inbreeding depression from SNP dataYengo, Loic, Zhu, Zhihong, Wray, Naomi R., Weir, Bruce S., Yang, Jian, Robinson, Matthew R. and Visscher, Peter M. (2018). Reply to Kardos et al.: estimation of inbreeding depression from SNP data. Proceedings of the National Academy of Sciences, 115 (11), E2494-E2495. doi: 10.1073/pnas.1718598115 |
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2018 Journal Article Transformation of summary statistics from linear mixed model association on all-or-none traits to odds ratioLloyd-Jones, Luke R., Robinson, Matthew R., Yang, Jian and Visscher, Peter M. (2018). Transformation of summary statistics from linear mixed model association on all-or-none traits to odds ratio. Genetics, 208 (4), 1397-1408. doi: 10.1534/genetics.117.300360 |
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2018 Journal Article Seasonal Variability of Mineral Formation in Microbial Mats Subjected to Drying and Wetting Cycles in Alkaline and Hypersaline Sedimentary EnvironmentsCabestrero, O., Sanz-Montero, M. E., Arregui, L., Serrano, S. and Visscher, P. T. (2018). Seasonal Variability of Mineral Formation in Microbial Mats Subjected to Drying and Wetting Cycles in Alkaline and Hypersaline Sedimentary Environments. Aquatic Geochemistry, 24 (1), 79-105. doi: 10.1007/s10498-018-9333-2 |
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2018 Journal Article GWAS of epigenetic aging rates in blood reveals a critical role for TERTLu, Ake T., Xue, Luting, Salfati, Elias L., Chen, Brian H., Ferrucci, Luigi, Levy, Daniel, Joehanes, Roby, Murabito, Joanne M., Kiel, Douglas P., Tsai, Pei-Chien, Yet, Idil, Bell, Jordana T., Mangino, Massimo, Tanaka, Toshiko, McRae, Allan F., Marioni, Riccardo E., Visscher, Peter M., Wray, Naomi R., Deary, Ian J., Levine, Morgan E., Quach, Austin, Assimes, Themistocles, Tsao, Philip S., Absher, Devin, Stewart, James D., Li, Yun, Reiner, Alex P., Hou, Lifang, Baccarelli, Andrea A. ... Horvath, Steve (2018). GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications, 9 (1) 387, 387. doi: 10.1038/s41467-017-02697-5 |
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2018 Journal Article Causal associations between risk factors and common diseases inferred from GWAS summary dataZhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J, Visscher, Peter M, Wray, Naomi R and Yang, Jian (2018). Causal associations between risk factors and common diseases inferred from GWAS summary data. Nature Communications, 9 (1) 224, 224. doi: 10.1038/s41467-017-02317-2 |
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2018 Journal Article Evidence of directional and stabilizing selection in contemporary humansSanjak, Jaleal S., Sidorenko, Julia, Robinson, Matthew R., Thornton, Kevin R. and Visscher, Peter M. (2018). Evidence of directional and stabilizing selection in contemporary humans. Proceedings of the National Academy of Sciences of the United States of America, 115 (1), 151-156. doi: 10.1073/pnas.1707227114 |
