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2014 Journal Article Practical lessons in murine thoracic lymph duct cannulations: Observations in female and male mice across four different strains that impact on cannulatabilityCaliph, Suzanne M., Shackleford, David M., Ascher, David B. and Kaminskas, Lisa M. (2014). Practical lessons in murine thoracic lymph duct cannulations: Observations in female and male mice across four different strains that impact on cannulatability. Journal of Pharmaceutical Sciences, 104 (3), 1207-1209. doi: 10.1002/jps.24312 |
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2014 Journal Article Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancersRyan, Gemma M., Kaminskas, Lisa M. and Porter, Christopher J.H. (2014). Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers. Journal of Controlled Release, 193, 241-256. doi: 10.1016/j.jconrel.2014.04.051 |
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2014 Journal Article Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapyKaminskas, Lisa M., McLeod, Victoria M., Ryan, Gemma M., Kelly, Brian D., Haynes, John M., Williamson, Mark, Thienthong, Neeranat, Owen, David J. and Porter, Christopher J. H. (2014). Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy. Journal of Controlled Release, 183 (1), 18-26. doi: 10.1016/j.jconrel.2014.03.012 |
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2014 Journal Article The lymphatic system plays a major role in the intravenous and subcutaneous pharmacokinetics of trastuzumab in ratsDahlberg, Annette M., Kaminskas, Lisa M., Smith, Alanna, Nicolazzo, Joseph A., Porter, Christopher J. H., Bulitta, Jürgen B. and McIntosh, Michelle P. (2014). The lymphatic system plays a major role in the intravenous and subcutaneous pharmacokinetics of trastuzumab in rats. Molecular Pharmaceutics, 11 (2), 496-504. doi: 10.1021/mp400464s |
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2013 Journal Article PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicinRyan, Gemma M., Kaminskas, Lisa M., Bulitta, Juergen B., McIntosh, Michelle P., Owen, David J. and Porter, Christopher J. H. (2013). PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin. Journal of Controlled Release, 172 (1), 128-136. doi: 10.1016/j.jconrel.2013.08.004 |
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2013 Journal Article Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: the effect of polymers on the formation of an amorphous matrix for glassy state stabilization of biomacromoleculesSou, Tomás, McIntosh, Michelle P., Kaminskas, Lisa M., Prankerd, Richard J. and Morton, David A. V. (2013). Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: the effect of polymers on the formation of an amorphous matrix for glassy state stabilization of biomacromolecules. Drying Technology, 31 (13-14), 1451-1458. doi: 10.1080/07373937.2013.788019 |
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2013 Journal Article Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependentRyan, Gemma M., Kaminskas, Lisa M., Kelly, Brian D., Owen, David J., McIntosh, Michelle P. and Porter, Christopher J. H. (2013). Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent. Molecular Pharmaceutics, 10 (8), 2986-2995. doi: 10.1021/mp400091n |
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2013 Journal Article Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniaeVelkov, Tony, Deris, Zakuan Z., Huang, Johnny X., Azad, Mohammad A. K., Butler, Mark, Sivanesan, Sivashangarie, Kiminskas, Lisa M., Dong, Yao-Da, Boyd, Ben, Baker, Mark A., Cooper, Matthew A., Nation, Roger L. and Li, Jian (2013). Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae. Innate Immunity, 20 (4), 350-363. doi: 10.1177/1753425913493337 |
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2013 Journal Article PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastasesKaminskas, Lisa M., Ascher, David B., McLeod, Victoria M., Herold, Marco J., Le, Caroline P., Sloan, Erica K. and Porter, Christopher J. H. (2013). PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases. Journal of Controlled Release, 168 (2), 200-208. doi: 10.1016/j.jconrel.2013.03.006 |
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2013 Journal Article The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromoleculesSou, Tomás, Kaminskas, Lisa M., Nguyen, Tri-Hung, Carlberg, Renée, McIntosh, Michelle P. and Morton, David A.V. (2013). The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules. European Journal of Pharmaceutics and Biopharmaceutics, 83 (2), 234-243. doi: 10.1016/j.ejpb.2012.10.015 |
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2012 Journal Article Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stressBurcham, Philip C., Raso, Albert and Kaminskas, Lisa M. (2012). Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stress. Molecular Pharmacology, 82 (5), 876-886. doi: 10.1124/mol.112.078956 |
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2012 Journal Article Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor modelsKaminskas, Lisa M., McLeod, Victoria M., Kelly, Brian D., Cullinane, Carleen, Sberna, Gian, Williamson, Mark, Boyd, Ben J., Owen, David J. and Porter, Christopher J. H. (2012). Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models. Molecular Pharmaceutics, 9 (3), 422-432. doi: 10.1021/mp200522d |
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2012 Journal Article Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulationKaminskas, Lisa M., McLeod, Victoria M., Porter, Christopher J. H. and Boyd, Ben J. (2012). Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation. Molecular Pharmaceutics, 9 (3), 355-373. doi: 10.1021/mp2005966 |
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2012 Journal Article A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systemsKaminskas, Lisa M., McLeod, Victoria M., Kelly, Brian D., Sberna, Gian, Boyd, Ben J., Williamson, Mark, Owen, David J. and Porter, Christopher J. H. (2012). A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems. Nanomedicine: Nanotechnology, Biology and Medicine, 8 (1), 103-111. doi: 10.1016/j.nano.2011.05.013 |
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2012 Journal Article Erratum: Dendrimer pharmacokinetics: The effect of size, structure and surface characteristics on ADME properties (Nanomedicine (2011) 6:6 (1063-1084))Kaminskas, Lisa M., Boyd, Ben J. and Porter, Christopher J.H. (2012). Erratum: Dendrimer pharmacokinetics: The effect of size, structure and surface characteristics on ADME properties (Nanomedicine (2011) 6:6 (1063-1084)). Nanomedicine, 7 (1). doi: 10.2217/nnm.11.173 |
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2011 Journal Article Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: a design of experiment approachSou, Tomas, Orlando, Laurence, McIntosh, Michelle P., Kaminskas, Lisa M. and Morton, David A. V. (2011). Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: a design of experiment approach. International Journal of Pharmaceutics, 421 (2), 220-229. doi: 10.1016/j.ijpharm.2011.09.018 |
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2011 Journal Article Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearanceKaminskas, Lisa M., Mcleod, Victoria M., Porter, Christopher J. H. and Boyd, Ben J. (2011). Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance. Journal of Pharmaceutical Sciences, 100 (11), 5069-5077. doi: 10.1002/jps.22682 |
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2011 Journal Article Targeting the lymphatics using dendritic polymers (dendrimers)Kaminskas, Lisa M. and Porter, Christopher J. H. (2011). Targeting the lymphatics using dendritic polymers (dendrimers). Advanced Drug Delivery Reviews, 63 (10-11), 890-900. doi: 10.1016/j.addr.2011.05.016 |
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2011 Journal Article Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME propertiesKaminskas, Lisa M., Boyd, Ben J. and Porter, Christopher J. H. (2011). Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties. Nanomedicine, 6 (6), 1063-1084. doi: 10.2217/nnm.11.67 |
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2011 Journal Article Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linkerKaminskas, Lisa M., Kelly, Brian D., McLeod, Victoria M., Sberna, Gian, Owen, David J., Boyd, Ben J. and Porter, Christopher J. H. (2011). Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker. Journal of Controlled Release, 152 (2), 241-248. doi: 10.1016/j.jconrel.2011.02.005 |
