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2006 Other Outputs Protein tyrosine pPhosphatase inhibitors and methods of use thereofBlaskovich, Mark A., Baughman, Ted, Little, Thomas, Patt, William, Qabar, Maher, Schultz, Lauri, Hong, Feng, Nagula, Gangadhar, Gage, Jennifer Lynn and Howbert, James Jeffry (2006). Protein tyrosine pPhosphatase inhibitors and methods of use thereof. WO/2006/055525. |
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2005 Journal Article Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-1Carrico, D, Blaskovich, MA, Bucher, CJ, Sebti, SM and Hamilton, AD (2005). Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-1. Bioorganic & Medicinal Chemistry, 13 (3), 677-688. doi: 10.1016/j.bmc.2004.10.053 |
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2004 Journal Article In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeabilityCarrico, D, Ohkanda, J, Kendrick, H, Yokoyama, K, Blaskovich, MA, Bucher, CJ, Buckner, FS, Van Voorhis, WC, Chakrabarti, D, Croft, SL, Gelb, MH, Sebti, SM and Hamilton, AD (2004). In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. Bioorganic & Medicinal Chemistry, 12 (24), 6517-6526. doi: 10.1016/j.bmc.2004.09.020 |
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2004 Journal Article Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screeningGasparetto, M, Gentry, T, Sebti, S, O'Bryan, E, Nimmanapalli, R, Blaskovich, MA, Bhalla, K, Rizzieri, D, Haaland, P, Dunne, J and Smith, C (2004). Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screening. Journal of Immunological Methods, 292 (1-2), 59-71. doi: 10.1016/j.jim.2004.06.003 |
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2003 Other Outputs Beta-sheet mimetics and composition and methods relating theretoOgbu, Cyprian O., Kim, Hwa-Ok and Blaskovich, Mark, A. (2003). Beta-sheet mimetics and composition and methods relating thereto. WO/2003/068237. |
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2003 Journal Article Design and synthesis of phosphotyrosine mimeticsYan, Zheng, Kahn, Michael, Qabar, Maher, Urban, Jan, Kim, Hwa-Ok and Blaskovich, Mark (2003). Design and synthesis of phosphotyrosine mimetics. Bioorganic & Medicinal Chemistry Letters, 13 (12), 2083-2085. doi: 10.1016/S0960-894X(03)00253-1 |
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2002 Journal Article Recent discovery and development of protein tyrosine phosphatase inhibitorsBlaskovich, Mark A. and Kim, Hwa-Ok (2002). Recent discovery and development of protein tyrosine phosphatase inhibitors. Expert Opinion on Therapeutic Patents, 12 (6), 871-905. doi: 10.1517/13543776.12.6.871 |
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2002 Journal Article Preparation of 1-[N-benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo[2.2.2] octane: [Carbamic acid, [1-(4-methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-2-oxoethyl]-, phenylmethyl ester, (S)-]Rose, Nicholas G. W., Blaskovich, Mark A., Evindar, Ghotas, Wilkinson, Scott, Luo, Yue, Fishlock, Dan, Reid, Chris, Lajoie, Gilles A., Gordon, Richard S. and Holmes, Andrew B. (2002). Preparation of 1-[N-benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo[2.2.2] octane: [Carbamic acid, [1-(4-methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-2-oxoethyl]-, phenylmethyl ester, (S)-]. Organic Syntheses, 79 doi: 10.15227/orgsyn.079.0216 |
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2002 Journal Article Preparation of 1-[N-Benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo-[2.2.2]octaneRose, Nicholas G.W., Blaskovich, Mark A., Evindar, Ghotas, Wilkinson, Scott, Luo, Yue, Reid, C. and Lajoie, Gilles A. (2002). Preparation of 1-[N-Benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo-[2.2.2]octane. Organic syntheses, 79, 216-221. doi: 10.1002/0471264180.os079.26 |
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2001 Conference Publication 4-substituted urazoles from amino acids: Useful building-blocks for the synthesis of beta-strand peptidomimetics.Paparin, JL, Hwang, SH, Nguyen, M, Zheng, Y, Ruan, FQ, Little, T and Blaskovich, MA (2001). 4-substituted urazoles from amino acids: Useful building-blocks for the synthesis of beta-strand peptidomimetics.. WASHINGTON: AMER CHEMICAL SOC. |
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2001 Conference Publication Facile synthesis of alpha-amino alcohols from alpha-amino acids.Hwang, SH, Blaskovich, M and Kim, HO (2001). Facile synthesis of alpha-amino alcohols from alpha-amino acids.. WASHINGTON: AMER CHEMICAL SOC. |
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2001 Conference Publication Design and synthesis of phosphotyrosine mimetic phenylalanine derivatives.Kim, HO, Yan, Z, Blaskovich, M and Kahn, M (2001). Design and synthesis of phosphotyrosine mimetic phenylalanine derivatives.. WASHINGTON: AMER CHEMICAL SOC. |
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2001 Journal Article Synthesis of enantiomerically enriched beta,gamma-unsaturated-alpha-amino acidsRose, Ngw, Blaskovich, MA, Wong, A and Lajoie, GA (2001). Synthesis of enantiomerically enriched beta,gamma-unsaturated-alpha-amino acids. Tetrahedron, 57 (8), 1497-1507. doi: 10.1016/S0040-4020(00)01146-7 |
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2000 Conference Publication Highly efficient and versatile construction of secondary structure peptide mimetic libraries: Application to biology and drug developmentBlaskovich, MA, Boatman, PD, Cao, BL, Eguchi, M, Kim, HO, Lee, M, Little, T, Mathew, F, McCann, I, Mehlin, C, Nakanishi, H, Nelson, S, Nguyen, M, Ogbu, C, Qabar, MN, Ruan, FQ, Shea, JP, Stasiak, M, Urban, J and Kahn, M (2000). Highly efficient and versatile construction of secondary structure peptide mimetic libraries: Application to biology and drug development. 16th American Peptide Symposium, Minneapolis Mn, Jun 26-Jul 01, 1999. DORDRECHT: SPRINGER. |
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1999 Journal Article Stereoselective synthesis of beta-substituted alpha,beta-diamino acids from beta-hydroxy amino acidsLuo, Y, Blaskovich, MA and Lajoie, GA (1999). Stereoselective synthesis of beta-substituted alpha,beta-diamino acids from beta-hydroxy amino acids. Journal of Organic Chemistry, 64 (16), 6106-6111. doi: 10.1021/jo9904718 |
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1998 Journal Article Highly efficient and versatile synthesis of libraries of constrained beta-strand mimeticsOgbu, CO, Qabar, MN, Boatman, PD, Urban, J, Meara, JP, Ferguson, MD, Tulinsky, J, Lum, C, Babu, S, Blaskovich, MA, Nakanishi, H, Ruan, FQ, Cao, BL, Minarik, R, Little, T, Nelson, S, Nguyen, M, Gall, A and Kahn, M (1998). Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics. Bioorganic & Medicinal Chemistry Letters, 8 (17), 2321-2326. doi: 10.1016/S0960-894X(98)00420-X |
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1998 Journal Article Polymer-supported acetylide addition to hexa-2,4-dienalBlaskovich, MA and Kahn, M (1998). Polymer-supported acetylide addition to hexa-2,4-dienal. Synthesis-Stuttgart (7), 965-966. |
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1998 Journal Article Stereoselective synthesis of Threo and Erythro beta-hydroxy and beta-disubstituted-beta-hydroxy alpha-amino acids (vol 63, pg 3635, 1998)Blaskovich, MA, Evindar, G, Rose, NGW, Wilkinson, S, Luo, Y and Lajoie, GA (1998). Stereoselective synthesis of Threo and Erythro beta-hydroxy and beta-disubstituted-beta-hydroxy alpha-amino acids (vol 63, pg 3635, 1998). Journal of Organic Chemistry, 63 (13), 4560-4560. doi: 10.1021/jo9849853 |
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1998 Journal Article Stereoselective synthesis of threo and erythro beta-hydroxy and beta-disubstituted-beta-hydroxy alpha-amino acidsBlaskovich, MA, Evindar, G, Rose, NGW, Wilkinson, S, Luo, Y and Lajoie, GA (1998). Stereoselective synthesis of threo and erythro beta-hydroxy and beta-disubstituted-beta-hydroxy alpha-amino acids. Journal of Organic Chemistry, 63 (11), 3631-3646. doi: 10.1021/jo972294l |
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1998 Journal Article Regiocontrol in alkylations of alpha-silyl hydrazonesBlaskovich, MA and Rickards, RW (1998). Regiocontrol in alkylations of alpha-silyl hydrazones. Tetrahedron Letters, 39 (21), 3617-3620. doi: 10.1016/S0040-4039(98)00564-4 |
