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2019

Journal Article

Quinolone antibiotics

Pham, Thu D. M., Ziora, Zyta M. and Blaskovich, Mark A. T. (2019). Quinolone antibiotics. MedChemComm, 10 (10), 1719-1739. doi: 10.1039/c9md00120d

Quinolone antibiotics

2019

Journal Article

Effects of microplate type and broth additives on microdilution MIC susceptibility assays

Kavanagh, Angela, Ramu, Soumya, Gong, Yujing, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Effects of microplate type and broth additives on microdilution MIC susceptibility assays. Antimicrobial Agents and Chemotherapy, 63 (1) e01760-18. doi: 10.1128/aac.01760-18

Effects of microplate type and broth additives on microdilution MIC susceptibility assays

2018

Journal Article

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

Jarrad, Angie M., Ang, Chee Wei, Debnath, Anjan, Hahn, Hye Jee, Woods, Kyra, Tan, Lendl, Sykes, Melissa L., Jones, Amy J., Pelingon, Ruby, Butler, Mark S., Avery, Vicky M., West, Nicholas P., Karoli, Tomislav, Blaskovich, Mark A. T. and Cooper, Matthew A. (2018). Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity. Journal of Medicinal Chemistry, 61 (24) acs.jmedchem.8b01578, 11349-11371. doi: 10.1021/acs.jmedchem.8b01578

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

2018

Journal Article

Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate

Pitt, Miranda E., Cao, Minh Duc, Butler, Mark S., Ramu, Soumya, Ganesamoorthy, Devika, Blaskovich, Mark A. T., Coin, Lachlan J. M. and Cooper, Matthew A. (2018). Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate. The Journal of Antimicrobial Chemotherapy, 74 (3), 582-593. doi: 10.1093/jac/dky458

Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate

2018

Journal Article

Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017)

Sim, Wilson, Barnard, Ross, Blaskovich, M.A.T. and Ziora, Zyta (2018). Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017). Antibiotics, 7 (4) 93, 93. doi: 10.3390/antibiotics7040093

Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017)

2018

Journal Article

Silver bullets: a new lustre on an old antimicrobial agent

Möhler, Jasper S., Sim, Wilson, Blaskovich, Mark A. T., Cooper, Matthew A. and Ziora, Zyta M. (2018). Silver bullets: a new lustre on an old antimicrobial agent. Biotechnology Advances, 36 (5), 1391-1411. doi: 10.1016/j.biotechadv.2018.05.004

Silver bullets: a new lustre on an old antimicrobial agent

2018

Journal Article

Detection and investigation of Eagle effect resistance to vancomycin in Clostridium difficile with an ATP-bioluminescence assay

Jarrad, Angie M., Blaskovich, Mark A. T., Prasetyoputri, Anggia, Karoli, Tomislav, Hansford, Karl A. and Cooper, Matthew A. (2018). Detection and investigation of Eagle effect resistance to vancomycin in Clostridium difficile with an ATP-bioluminescence assay. Frontiers in Microbiology, 9 (JUL) 1420, 1420. doi: 10.3389/fmicb.2018.01420

Detection and investigation of Eagle effect resistance to vancomycin in Clostridium difficile with an ATP-bioluminescence assay

2018

Other Outputs

Visualisation Constructs

Mark Blaskovich, Matt Cooper, Mark Butler, Rhia Stone and Wanida Phetsang (2018). Visualisation Constructs. WO/2018/102890.

Visualisation Constructs

2018

Other Outputs

Glycopeptide Antibiotic Constructs

Mark Blaskovich, Matt Cooper, Andrea Ranzoni, Wanida Phetsang and Marwa Hassan (2018). Glycopeptide Antibiotic Constructs. WO/2018/102889.

Glycopeptide Antibiotic Constructs

2018

Journal Article

The fight against antimicrobial resistance is confounded by a global increase in antibiotic usage

Blaskovich, Mark A. T. (2018). The fight against antimicrobial resistance is confounded by a global increase in antibiotic usage. ACS Infectious Diseases, 4 (6), 868-870. doi: 10.1021/acsinfecdis.8b00109

The fight against antimicrobial resistance is confounded by a global increase in antibiotic usage

2018

Journal Article

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

Pitt, Miranda E., Elliott, Alysha G., Cao, Minh Duc, Ganesamoorthy, Devika, Karaiskos, Ilias, Giamarellou, Helen, Abboud, Cely S., Blaskovich, Mark A. T., Cooper, Matthew A. and Coin, Lachlan J. M. (2018). Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae. Microbial Genomics, 4 (3) 000158. doi: 10.1099/mgen.0.000158

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

2018

Journal Article

Developments in Glycopeptide Antibiotics

Blaskovich, Mark A. T., Hansford, Karl A., Butler, Mark S., Jia, ZhiGuang, Mark, Alan E. and Cooper, Matthew A. (2018). Developments in Glycopeptide Antibiotics. ACS Infectious Diseases, 4 (5), 715-735. doi: 10.1021/acsinfecdis.7b00258

Developments in Glycopeptide Antibiotics

2017

Journal Article

A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase

Paparella, Ashleigh S., Feng, Jiage, Blanco-Rodriguez, Beatriz, Feng, Zikai, Phetsang, Wanida, Blaskovich, Mark A. T., Cooper, Matthew A., Booker, Grant W., Polyak, Steven W. and Abell, Andrew D. (2017). A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase. Tetrahedron, 74 (12), 1175-1183. doi: 10.1016/j.tet.2017.10.032

A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase

2017

Journal Article

Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1

Edwards, Ingrid A, Elliott, Alysha G, Kavanagh, Angela M, Blaskovich, Mark A T and Cooper, Matthew A (2017). Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1. ACS infectious diseases, 3 (12), 917-926. doi: 10.1021/acsinfecdis.7b00123

Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1

2017

Journal Article

Nitroimidazoles: Molecular fireworks that combat a broad spectrum of infectious diseases

Ang, Chee Wei, Jarrad, Angie M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2017). Nitroimidazoles: Molecular fireworks that combat a broad spectrum of infectious diseases. Journal of Medicinal Chemistry, 60 (18), 7636-7657. doi: 10.1021/acs.jmedchem.7b00143

Nitroimidazoles: Molecular fireworks that combat a broad spectrum of infectious diseases

2017

Journal Article

Investigating the interaction of octapeptin A3 with model bacterial membranes

Han, Mei-Ling, Shen, Hsin-Hui, Hansford, Karl A., Schneider, Elena K., Sivanesan, Sivashangarie, Roberts, Kade D., Thompson, Philip E., Le Brun, Anton P., Zhu, Yan, Sani, Marc-Antoine, Separovic, Frances, Blaskovich, Mark A. T., Baker, Mark A., Moskowitz, Samuel M., Cooper, Matthew A., Li, Jian and Velkov, Tony (2017). Investigating the interaction of octapeptin A3 with model bacterial membranes. ACS Infectious Diseases, 3 (8), 606-619. doi: 10.1021/acsinfecdis.7b00065

Investigating the interaction of octapeptin A3 with model bacterial membranes

2017

Journal Article

From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators

Hussein, Maytham H., Schneider, Elena K., Elliott, Alysha G., Han, Meiling, Reyes-Ortega, Felisa, Morris, Faye, Blaskovich, Mark A. T., Jasim, Raad, Currie, Bart, Mayo, Mark, Baker, Mark, Cooper, Matthew A., Li, Jian and Velkov, Tony (2017). From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators. Microbial Drug Resistance, 23 (5), 640-650. doi: 10.1089/mdr.2016.0196

From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators

2017

Journal Article

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria

Becker, Bernd, Butler, Mark S., Hansford, Karl A., Gallardo-Godoy, Alejandra, Elliott, Alysha G., Huang, Johnny X., Edwards, David J., Blaskovich, Mark A. T. and Cooper, Matthew A. (2017). Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria. Bioorganic and Medicinal Chemistry Letters, 27 (11), 2407-2409. doi: 10.1016/j.bmcl.2017.04.027

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria

2017

Journal Article

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

Desselle, Mathilde R., Neale, Ruth, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2017). Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals. Future Science OA, 3 (2) FSO171, FSO171. doi: 10.4155/fsoa-2016-0093

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

2017

Journal Article

Polishing the tarnished silver bullet: the quest for new antibiotics

Blaskovich, Mark A. T., Butler, Mark S. and Cooper, Matthew A. (2017). Polishing the tarnished silver bullet: the quest for new antibiotics. Antimicrobial Resistance, 61 (1), 103-114. doi: 10.1042/EBC20160077

Polishing the tarnished silver bullet: the quest for new antibiotics